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PODCAST

Talking Biotech with Dr. Kevin Folta

Talking Biotech is a weekly podcast that uncovers the stories, ideas and research of people at the frontier of biology and engineering. Each episode explores how science and technology will transform agriculture, protect the environment, and feed 10 billion people by 2050. Interviews are led by Dr. Kevin Folta, a professor of molecular biology and genomics.

science life sciences

All Episodes

44:04

Resistance to Correction, Breaking Trust in Science -...

Talking Biotech with Dr. Kevin Folta ·

2024/07/21

Disinformation clouds the public understanding of science, especially technology in agriculture and medicine. So when a leading journal publishes false information, academic experts have an obligation to help correct the process. This may be done via a variety of methods, but cordial and collegial discussion is the first step. When that fails, notes to editors and authors are in order. When that fails, written point-by-point rebuttals are required. But what happens when that fails? An

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42:32

Your Role in Editing Wikipedia - Susan Gerbic

Talking Biotech with Dr. Kevin Folta ·

2024/06/29

Wikipedia is the go-to source for many people when starting to research a subject. But is the information correct, or does the information even exist in Wikipedia at all? Susan Gerbic has been training people to edit Wikipedia pages through the Gorilla Skeptics of Wikipedia project. They have edited tens of thousands of pages with over 16 million views. Susan describes the process as well as how you can be involved in correcting online false information.

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32:06

Gene Editing in Specialty Crops - Dr. Tom Adams, CEO...

Talking Biotech with Dr. Kevin Folta ·

2024/06/22

Crop genetic engineering has focused primarily on large-acreage crops like corn. But what about the universe of specialty crops that tantalize consumers, things like blackberries or salad greens? Pairwise has used precision twists on gene editing to change specific traits in fruit and vegetable crops. Pairwise founder and CEO, Dr. Tom Adams, discusses the current progress, general philosophy, and moonshot plans for bringing exciting new specialty crops to market.

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33:33

Special Panel - From Pre-Clinical to Clinical Trials

Talking Biotech with Dr. Kevin Folta ·

2024/06/15

Advancement of a new drug from pre-clinical trials to clinical trials is a pivotal time in validation of its therapeutic effects and safety. A panel of experts discusses the process.

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63:32

Talking Biotech Begins Year 10! with Dr. Liza Dunn

Talking Biotech with Dr. Kevin Folta ·

2024/06/08

Today's episode marks the beginning of the 10th year of the Talking Biotech Podcast. To celebrate, Drs. Liza Dunn and Kevin Folta discuss the last decade of biotech breakthroughs and communications efforts, the fight against technology and the amazing progress in gene editing and human genetic therapies. Plus, what you can do to help the effort going forward.

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47:33

Targeting Chronic Inflammation Via the Inflamasome -...

Talking Biotech with Dr. Kevin Folta ·

2024/06/02

Chronic inflammation goes hand-in-hand with many diseases, complicating symptoms and affecting routes of treatment. What is the molecular basis of inflammation, and can it be targeted by new drugs? Scientists have studied the molecular basis of the inflammatory response and have identified specific proteins that complex to initiate the response. New drugs are showing promise in breaking the inflammatory cascade. Studies of genealogical records revealed additional targets that modify known

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29:40

Development of Biotech Partnerships

Talking Biotech with Dr. Kevin Folta ·

2024/05/25

Strategic partnerships are becoming more important in development and deployment of biotechnology solutions. Today's panel discusses the way partnerships are formed, some of the important considerations with IP and licensing, and how relationships are managed.

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27:59

Journal Club - Were "High Levels" of Glyphosate Found...

Talking Biotech with Dr. Kevin Folta ·

2024/05/22

The news reports say that scientists have found "high levels" of herbicide in human sperm, and suggest it is a cause of infertility. But what do the data really say? Dr. Andrea Love and I discuss the paper. A report by Vasseur et al., in the June 2024 Ecotoxicology and Environmental Safety entitled Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population strongly implies a tight connection between the herbicide

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47:53

Standardizing Therapeutic Protein Production in...

Talking Biotech with Dr. Kevin Folta ·

2024/05/18

Where many therapeutic compounds are raised in bacteria or fungi, plants sometimes offer many advantages as bioreactors. Capital and production costs are lower, and products may be edible instead of injectable. The problem tends to be standardization, and conditions that ensure that the desired proteins are produced This episode features Jim Wilson from Zea Biologics, where cleanrooms, precise regulation of all aspects of the plant growth environment, and massive data collection, allow for

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27:00

Canadian Rules for Gene Editing - Jennifer Hubert

Talking Biotech with Dr. Kevin Folta ·

2024/05/11

Canada has a unique approach to plant genetic improvement that follows the product, not the process. In other words, if there is potential risk from any genetic manipulation technique, from polyploidization to transgenic to gene edits, Canadian regulators assess the relative risk in the final product. But what does the regulatory climate look like going forward as gene editing becomes more routine? Today's podcast is a conversation with Jennifer Hubert, Executive Director of Biotechnology

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46:50

Overcoming CAR-T Cell Bottlenecks - Dr. Andy Scherenberg

Talking Biotech with Dr. Kevin Folta ·

2024/05/04

Immunotherapy is weaponizing the body's immune system against cancer or other disease. One of the most promising approaches is CAR-T cell therapy, yet as this technology has been implemented, it's limitations have been identified. Dr. Andy Schernberg described the current drawbacks of CAR-T cells and how his company, Umoja, is re-engineering CAR-T cells in vivo to create more effective therapies, including approaches that can address solid tumors. Co-hosted by Donald

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61:33

The FDA Regulatory Ecosystem- Expert Panel Discusses...

Talking Biotech with Dr. Kevin Folta ·

2024/04/27

How do new drug applications move forward to approval? Four experts discuss the partnership between the FDA, the drug developer, and the data needed to move a product forward. It is a surprising discussion that reveals the depth of the FDA process. Joined by Dr. Debra Webster, Dr. Julia Marre, Dr. Michael Matthews and Dr. Jonathan Helfgott.

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41:35

The Psychology of Risk - Dr. Felicia Wu

Talking Biotech with Dr. Kevin Folta ·

2024/04/20

We live in amazing times of technological advance, but how are the real benefits of new tech lost to an inflated sense of risk? Dr. Felicia Wu from Michigan State University shares her expertise in describing the psychological basis of risk and applying it to questions like glyphosate and aspartame.

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31:49

Restoring the Forest with GE American Chestnut - Dr....

Talking Biotech with Dr. Kevin Folta ·

2024/04/06

This is an update on the American Chestnut Restoration Project, as discussed previously on the podcast. The American Chestnut dominated the forests of Appalachia until an imported fungus destroyed the entire range. Efforts to restore the chestnut and its ecology have employed a biotechnology approach, integrating a gene from wheat that limits the mechanism the fungus uses to attack the tree. Dr. Andy Newhouse and Erik Carlson join the podcast to discuss progress in the project.

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40:12

Addressing Disparities in Women's Healthcare -...

Talking Biotech with Dr. Kevin Folta ·

2024/03/30

Despite being over half of the population women's health care lags behind other areas of drug development. The problem is caused by many facets, but is augmented by the fact that many of the conditions are not life threatening or are functions of aging. Sabrina Johnson, CEO of Daré Biosciences, discusses how the disparity exists, the pipeline of drugs that seek to mitigate female-specific conditions, and how smaller, leaner businesses can have significant impacts in this space.

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30:20

Return of Talking Biotech; Stories in the News

Talking Biotech with Dr. Kevin Folta ·

2024/03/23

After a three month hiatus the Talking Biotech Podcast is back. Today's episode is a visit with Colarbra CEO Aoi Senju about his view for the podcast, followed by synopsis of three major news stories that broke since the last Talking Biotech Podcast. The new format includes a video component, and I'll be speaking with panels and also discussing recent news stories. It is an exciting opportunity to capture a new audience, expand listenership, and provide new levels of programming to the

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7:18

Temporary Hiatus, Changes Coming!

Talking Biotech with Dr. Kevin Folta ·

2023/11/27

After 8.5 years of weekly podcasts I'm going to take a 5 week break and plan new episodes for 2024. I'm going through a medical glitch that has me unable to do my normal work. On top of this we're going to switch to an audio plus video format to find a wider audience. So check back in 2024 for the next episode. Have a great rest of 2023, thank you for listening, and looking forward to better times.

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35:46

A Novel RNAi Approach to Crop Protection - Todd Hauser

Talking Biotech with Dr. Kevin Folta ·

2023/11/18

Even under the best conditions, crops need our assistance to survive the numerous threats that limit production. Classically, synthetic and natural compounds have been used to control insects, fungi and weeds, sometimes with negative collateral effects or fostering resistance of genetically tolerant genotypes. Todd Hauser from Trillium Ag describes his company's novel RNAi approach. RNAi can be used to target specific insect species, and his company's design and particle-based technology

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42:07

Drugs from the Rainforest - Lisa Conte

Talking Biotech with Dr. Kevin Folta ·

2023/11/11

There is tremendous variation in the plant kingdom, as plants have adapted to many ecological niches with discrete challenges. Part of adaptation is production of novel secondary metabolites, compounds not required for central metabolism that serve a role in the plant, such as defense or attraction of pollinators. The rainforest is replete with unusual plants and their resident metabolites. Indigenous peoples have identified therapeutic qualities of specific plants. How can this knowledge

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49:16

Proposed Gene Editing Changes in the EU -Dr. Emma Kovak

Talking Biotech with Dr. Kevin Folta ·

2023/11/04

Gene editing is a powerful and specific technique that allows customized changes to DNA. Because there are no additional sequences transferred, and alternations match what could happen naturally over time, the technology is considered less invasive and less prone to regulatory oversight. That's true in the USA, Canada, China and other nations. However, the European Court of Justice determined that these techniques should be regulated in a manner identical to transgenics, where the EU has

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477 results

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