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PODCAST

The Joe Cohen Show

Unlock the secrets of your DNA and optimize your health with The Joe Cohen Show. Join Joe, biohacker and founder of SelfDecode, as he interviews world-class health experts and shares cutting-edge research and strategies for biohacking your body and brain. From functional medicine tips and supplement recommendations to longevity and performance optimization, each episode is packed with insights to help you achieve your health goals. Whether you"re interested in genetics, biohacking, alternative

health & fitness alternative health

All Episodes

01:05:41

Dr. Michael Snyder | How To Boost Your Longevity with...

The Joe Cohen Show ·

2024/07/05

In this episode, we dive deep into the world of precision health with Dr. Michael Snyder, a renowned professor of genetics at Stanford University and the chair of the genetics department. Join us as Dr. Snyder shares his groundbreaking insights on the latest advancements in precision medicine, biohacking, and personalized healthcare. Discover how cutting-edge technology, supplements, and genetic research can optimize your longevity and overall wellness. Tune in to learn how you can leverage

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00:47:55

Biohacking, Fitness and Longevity with Jean Fallacara

The Joe Cohen Show ·

2024/06/14

In this episode, Joe speaks with Jean Fallacara, a multifaceted entrepreneur, neuroscientist, and calisthenics enthusiast. Jean shares insights on how he maintains peak performance through biohacking, focusing on supplements, exercise routines, and meditation practices. Joe and Jean dive deep into the realms of precision health, genetic testing, and maintaining a balanced, enjoyable lifestyle while pursuing optimal health. Tune in for an engaging discussion on fitness tips, the importance of

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00:12:08

How Proline Can Make You A Hypochondriac | Supplement...

The Joe Cohen Show ·

2024/06/07

In this episode, Joe dives into the complex world of proline supplementation.He discusses the impacts proline has on collagen synthesis, aiming for improved skin health, enhanced wound healing, and better exercise recovery. However, the journey took an unexpected turn as Joe explains the biomechanics behind why he experienced several side effects such as anxiety, restlessness, and hypochondriac behaviors. Throughout the episode, Joe explores: The intended benefits of proline for collagen

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00:18:13

Can This Outperform Caffeine for Better Focus? |...

The Joe Cohen Show ·

2024/05/31

Join Joe as he takes a closer look at saffron, a spice revered not just for its flavor but for its impressive health benefits. In this deep dive, Joe explores how saffron could potentially outshine caffeine in enhancing mental clarity and focus. This episode goes in-depth on how saffron impacts various aspects of health, from improving sleep quality to reducing gut inflammation and boosting immune function. Discover the comprehensive effects of saffron on: Mental Focus: How saffron compares to

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00:24:16

Decrease Your Heavy Metals by 75% With This...

The Joe Cohen Show ·

2024/05/24

Join Joe as he delves into his journey with MSM (Methyl Sulfonyl Methane) supplementation, a key to detoxing the body and enhancing recovery. In this episode, Joe discusses: The Impact of Heavy Metals on Health: Understanding the dangers of heavy metals and the importance of detoxing them from our bodies. MSM as a Detox & Methylation Aid: How MSM supplementation helps clear heavy metals and play a vital role in methylation. Recovery and Resilience Through MSM: How MSM aids in the

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00:17:28

Resistant Starch vs. Ozempic: A Natural Path to...

The Joe Cohen Show ·

2024/05/17

Buy Jo’s Resistant Starch on Amazon Join Joe as he explores the powerful benefits of resistant starch as a natural alternative to Ozempic. In this episode, Joe dives into how resistant starch not only supports weight management and cognitive function but also promotes gut health—all without the side effects associated with pharmaceutical options like Ozempic. Joe discusses: Resistant Starch for Health: How this natural supplement enhances the production of butyrate, GLP-1, and how these play

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00:47:12

Dr. Rita Marie on Integrating Personalized Health...

The Joe Cohen Show ·

2024/05/10

In this episode, Joe has an in-depth conversation with Dr. Rita Marie, a licensed doctor of chiropractic and the founder of the Institute of Nutritional Endocrinology, about the importance of personalized healthcare in addressing insulin, thyroid, adrenal, and digestive imbalances through the integration of genetics and lifestyle changes. Dr. Rita Marie discusses her approach to helping patients by not only looking at conventional lab tests but also incorporating genetics and lifestyle factors such

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00:14:40

Can AKG Make You Anxious?: The Pros & Cons of This...

The Joe Cohen Show ·

2024/05/03

In this episode, Joe dives deep into the effects of megadosing AKG (Alpha Ketoglutarate), a crucial supplement in metabolic pathways and its implications for longevity. Discover the risks and rewards as Joe recounts increasing his AKG intake to 15 times the standard dosage, leading to notable side effects such as enhanced anxiety and sleep issues. Joe meticulously explains the biochemical transformation of AKG into glutamate and reviews strategies to counteract these negative impacts, including the

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00:05:01

How Betaine and BHMT Influence Your Methylation |...

The Joe Cohen Show ·

2024/04/30

In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process. We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine. Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particularly in the reaction facilitated by the BHMT enzyme, making it crucial for reducing homocysteine levels and supporting cardiovascular and

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00:27:22

Is Niacin Killing You?: Breaking Down The New Niacin...

The Joe Cohen Show ·

2024/04/26

In this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease. Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and increased energy levels. Joe draws on personal experiences to compare the negatives against the significant positives of niacin, as he explores niacin's

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00:05:52

The Science of Cannabinoids and the CNR1 Gene | SNPit...

The Joe Cohen Show ·

2024/04/24

In this episode, we explore the complex interplay between the CNR1 gene, cannabinoid receptors, and cannabis. Discover the role of the endocannabinoid system in maintaining bodily balance, particularly in brain function, mood regulation, and inflammation response. We delve deep into how genetic variations in the CNR1 gene can influence the CB1 receptors, and the implications of CB1 receptor function in managing stress, anxiety, and cognitive processes such as memory and decision-making. Whether

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00:07:13

Balance Serotonin and Decrease Anxiety With The HTR1A...

The Joe Cohen Show ·

2024/04/16

In this episode, we explore the crucial role of serotonin in managing anxiety and enhancing mental wellbeing. Discover how serotonin not only influences mood but also plays a pivotal role in anxiety regulation and mental health. Learn about the HTR1A and HTR2A genes, which act like switches, controlling the serotonin levels in the brain. Understanding the SNPs in these genes can provide personal insights into your serotonin activity, offering potential strategies to alleviate anxiety, depression,

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00:25:24

Q&A #03 - Answering Questions About SelfDecode

The Joe Cohen Show ·

2024/04/12

In this episode, Joe takes questions from SelfDecode members, answering questions like:What makes SelfDecode different from other DNA companies? How does the recommendations engine work? Can you find out if a certain supplement is right for you? Plus, he shares some of his genetic predispositions and how they correlate with his lab levels! - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/

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00:06:01

MTHFD1, Choline and Methylation | SNPit #16

The Joe Cohen Show ·

2024/04/09

In this episode, we delve into the critical process of methylation, highlighting its significant impact on health issues ranging from heart disease to mental health and focusing on a lesser known methylation gene - MTHFD1. We focus on the MTHFD1 gene and choline's significance beyond methylfolate and Vitamin B12 for undermethylators. Discover how MTHFD1 impacts methylation by metabolizing tetrahydrofolate and how choline is important in supplying methyl groups. We highlight the impact of a

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02:00:17

Dr Jack Kruse On Biohacking Your Water, EMFs, Blue...

The Joe Cohen Show ·

2024/04/05

This episode was originally published on April 12, 2015.Dr. Jack Kruse and Joe explore unconventional approaches to health through the lens of physics and biochemistry. They cover topics like the critical roles of mitochondrial function, environmental factors such as EMFs, blue light, and dietary choices on our well-being, and challenge common health paradigms, emphasizing the importance of circadian biology, the effects of cold exposure, water quality, and the necessity of questioning mainstream

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00:05:59

Dopamine, Serotonin, Norepinephrine, and MAOB | SNPit...

The Joe Cohen Show ·

2024/04/03

In this episode, we delve into the science behind the MAOB gene and monoamine neurotransmitters. Join us as we explore the crucial role of dopamine, serotonin, and norepinephrine in regulating mood and cognition. We dissect the function of the MAOB gene in metabolizing neurotransmitters and discuss the implications of genetic variations on mental health. From increased breakdown linked to mood disorders to decreased activity associated with elevated neurotransmitter levels, we unravel the complex

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00:57:29

Optimizing Functional Health Markers with The...

The Joe Cohen Show ·

2024/03/29

In this episode, Joe dives into the world of personalized wellness with Lauren Sambataro and Renee Belz, known as The Biohacker Babes.With roots in wellness and holistic dentistry, The Biohacker Babes bring their wealth of expertise as health entrepreneurs, nutritional consultants, and holistic lifestyle coaches to the table. In this enlightening conversation, we explore the pivotal role of lab testing in crafting personalized health regimens, emphasizing essential tests such as CBC, CMP, and

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00:04:22

Dopamine & The DRD2 Gene | SNPit #14

The Joe Cohen Show ·

2024/03/26

In this episode of The Joe Cohen Show, we dive deep into the world of dopamine. We'll be focusing on the role of genetics, specifically the DRD2 gene, in regulating dopamine levels and how it affects your brain's reward system, motivation, and susceptibility to addiction. Here's what you can expect to learn: How the DRD2 gene influences dopamine D2 receptors and their impact on pleasure-seeking behaviors. Understanding the variants of the DRD2 gene and its link to dopamine

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01:21:05

Tim Gray, Kris Gethin and Siim Land: Navigating...

The Joe Cohen Show ·

2024/03/22

Join us for an enlightening roundtable discussion featuring health experts Joe Cohen, Kris Gethin, Tim Gray, and Siim Land as they dive deep into the world of health optimization. In this episode, our expert panel explores a wide range of health tests and biomarkers, from basic to advanced, and what they mean for your health, including VO2 max assessments, heart rate variability, full-body MRI scans, gut microbiome analysis, and food sensitivity testing. We also discuss topics like EMF and heavy

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00:05:55

The Science of Relationships: A Look at OXTR and...

The Joe Cohen Show ·

2024/03/19

Love is in the air as we dive into the science behind relationships. In this episode, we explore the fascinating world of oxytocin, affectionately known as the "love hormone," and its connection to the OXTR gene. Responsible for encoding the oxytocin receptor, this gene plays a crucial role in shaping our social bonds, empathy levels, and even cognitive abilities. We discuss groundbreaking research, including the 'happy marriage study,' which unveils intriguing insights into how

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