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PODCAST

The Poison Lab

Clinical Toxicology LLC

Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical management of toxins from around the globe. From stories of those impacted to expert insights from pioneers

education life sciences

All Episodes

01:25:40

Episode #17- Toxicologists vs the Internet (#7) With...

The Poison Lab ·

2022/11/09

Recent Healthcare poisoning in the newsNurse reportedly feeding children insulin (all information is uncomfirmed) and killing 7 neonates (not all insulin related)Anesthesiologist charged with murder for 2000 mcg fentanyl doses given during care in ICUDiethylene glycol and Ethylene glycol outbreak in GambiaNot talked about in the show but physician spiking liter bags with bupivicaine to try to kill a colleague in 2022CasesCase 1Case 2 toxinsThe burden of empty Gatorade bottles on societyCase 3

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01:04:56

Episode #16- Phenibut. The emerging drug you don’t...

The Poison Lab ·

2022/09/12

More on St Anthony's fire CDC MWR Study documenting increased poison center exposures (Dr. Graves & Dr. Liebelt) Phenibut case series from Dr. McCabe All published cases of phenibut withdrawal, reported baclofen regimens, clinical outcomes, multimodal therapiesTHEORETICAL UNTESTED Phenibut withdrawal treatment schema (Not tested, not intended as treatment, intended to stimulate discussion and highlight key considerations in managing withdrawal)

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00:01:25

Episode 16 Mystery Case

The Poison Lab ·

2022/08/03

Do you think you know the cause of these symptoms? Send your guesses to toxtalk1@gmail.com to take part in episode 16

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01:16:02

Episode #15- Toxicologists vs the Internet (#6) With...

The Poison Lab ·

2022/07/06

Case report Ryan Feldman wrote about himselfStump the Tox casesCase #1Case #2case series from Dr Jillian TheobaldCase #3Case #4Ask drugsFanconi syndrome in expired tetracycline

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00:41:10

Episode #14- Fast and Fatalurious (Benzonatate)

The Poison Lab ·

2022/05/04

Digoxin kineticsAmiodarone overdosePost market safety reviewReview of published exposures and severe outcomes from US poison centerCase from the show

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00:01:05

Case Teaser Episode 14- Fast and Fatalurious

The Poison Lab ·

2022/03/30

Send in your guesses to toxtalk1@gmail.com

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01:21:49

Episode #13- Toxicologists vs the Internet (#5) With...

The Poison Lab ·

2022/03/02

Music from PixabayAdditional information on toxins from fatal poisoning cases Toxin 1Toxin 2Toxin 3Toxin 4Popper article referenced by Dr. Greller

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00:09:04

Where is Episode 13 ? Bonus Episodes AND Next Episode...

The Poison Lab ·

2022/02/02

No episode today. Head here for the live radio show! Join us next show for Dr. Howard Greller of Sirius XM Doctor Radio, Dantastic Mr Tox & Howard, and Tox & HoundFind the article about the poison lab here

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00:55:42

Episode #12- Lethal Buttock Injection (And Other...

The Poison Lab ·

2021/12/08

Music in this episode from pixabay.com IntroCase report of hemolysis after sodium deoxycholate injection HistoryEpidemiologyASPS statsFlorida Unlicensed Activity Unit Cost of surgeon fee for buttock implant 2018Recent new storiesBotox and Bubbles grifterQuick bio on cases mentioned in showCommon injection practicesFeminizing body contouring (pumping parties)Synthol musclesCapsule face cosmeticsToxicityInfectionSelf explanatoryFiller embolismReview 1, Review 2, Review 3Filler lodges in pulmonary

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00:01:21

Case Teaser Episode 12- CHALLENGING case of...

The Poison Lab ·

2021/10/06

Send in your guesses to toxtalk1@gmail.com

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01:03:05

Episode #11- Toxicologists vs the Internet (#4) With...

The Poison Lab ·

2021/10/06

Research from Dr FarkasAdditional information on toxins from Fatal poisoning cases Toxin 1Toxin 2Toxin 3Toxin 4"Toxicologist vs the internet" segmentCocaethylene reviewBenzodiazepine urine drug screening - Blog post

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00:27:32

Episode #10- You Left Your Bladder in The K-Hole?...

The Poison Lab ·

2021/08/04

HistoryDiscovery of KetamineMelamine outbreaksClinical EffectsIndex casesSurvey of Ketamine use prior to symptomsMechanism/TreatmentMechanism/Treatment systematic reviewRat models

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00:01:33

Case Teaser Episode 10: How to lose a bladder in 10...

The Poison Lab ·

2021/06/02

What substance could cause these symptoms? Send your guesses to Toxtalk1@gmail.com to participate in episode 10!

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01:06:13

Episode #9- Toxicologists vs the Internet (#3) With...

The Poison Lab ·

2021/06/02

"Toxicologist vs the internet" segmentEverythingisosm.com (Blog post)Biased Mu Receptor ligandsOliceridine mouse studiesOpioid hearing loss (Blog post)Opioid hearing loss reviewTox pupils (Blog post)Why tramadol is awful (Blog post)Additional information on toxins from Fatal poisoning cases Toxin 1Toxin 2Toxin 3Toxin 4

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00:21:08

Mini Episode: Setting The Record Straight on Delta 8...

The Poison Lab ·

2021/04/18

New york times article on delta 8 THChttps://www.nytimes.com/2021/02/27/health/marijuana-hemp-delta-8-thc.htmlStudies of delta 8 THC in manSystematic review that summarizes single studyhttps://pubmed.ncbi.nlm.nih.gov/29385080/Actual study(may not be accessible) https://www.karger.com/Article/Abstract/136375HPLCS-MS-MS delta 8 testing strategieshttps://academic.oup.com/jat/advance-article-abstract/doi/10.1093/jat/bkaa184/6018445?redirectedFrom=fulltext testingCannabanoid receptor

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00:37:07

Episode #8- More Bitter than Sweet (Mad Honey and...

The Poison Lab ·

2021/03/31

Case from the showhttps://pubmed.ncbi.nlm.nih.gov/22163140/Mithradateshttps://www.wemjournal.org/article/S1080-6032(11)00043-3/pdfCase series on mad honey effectshttps://pubmed.ncbi.nlm.nih.gov/20575670/Blog post on sodium channel openershttps://emcrit.org/toxhound/ff-plant-sodium-channel-openers/

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01:15:37

Episode #7- Toxicologists vs the Internet (#2) With...

The Poison Lab ·

2021/02/03

Things from the show!Ketamine for depression, patient experience bloghttps://humanparts.medium.com/30-years-of-depression-gone-3dffafabc7cf?fbclid=IwAR1gh08Kn3uSczlKbvMH54yjkWILzyA_6O3Y82q4hVqcAr3shozxwegCnmgFasoracetamhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770454/#CR14KavaHepatic injury- https://pubmed.ncbi.nlm.nih.gov/15114493/Anti anxiety effects- https://pubmed.ncbi.nlm.nih.gov/33207379/Cocaine chest painPropranolol effects on coronary constriction-

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00:09:51

Mini Episode: Managing Crashing...

The Poison Lab ·

2020/12/16

Quick reviewToxic doseChloroquine >5g severe toxicity is expected (toxicity may develop below this)HCQ less well defindClinical effectsSeizures (sodium channel blockade)Arrhythmia (sodium channel blockade)Hypotension (Alpha blockade)HypokalemiaManagementActivated Charcoal if awake and alert and no risk of emesisEarly invasive supportive care based on the following retrospective case control series https://www.nejm.org/doi/full/10.1056/NEJM198801073180101High dose epinephrine (0.25

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01:06:57

Episode #6- Barking Up the Wrong Tree (Cinohonism,...

The Poison Lab ·

2020/12/16

Historical perspective on use of cinchona bark powder for malariahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973170/Evolutionarily pressure of malaria on beta thalassemia (sickle sell) traitshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499995/CinchonismClassic toxicities causes by ingestion of quinoline derivatives found in the bark of the cinchona treeBrief review- https://pubmed.ncbi.nlm.nih.gov/32644745/EtiologyPowdered cinchona barkUsed by people to make tonic water, treat restless legs, or

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01:07:32

Episode #5- Toxicologists vs The Internet (#1) With...

The Poison Lab ·

2020/11/04

Article authored by Ryan and Matt regarding potential toxicity of vitamin e acetate in THC vape cartridgeshttps://pubmed.ncbi.nlm.nih.gov/32451600/https://pubmed.ncbi.nlm.nih.gov/33528766/News article about the man arrested 1 floor below our Host where co-author of above paper is quouted. for selling vape cartridgeshttps://www.jsonline.com/story/news/2019/08/29/vaping-deaths-thc-cartridges-investigated-wisconsin-cases/2154799001/False Positive for

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