x

75% of people globally want unbiased news (Pew Research) but are concerned they're not getting that.

Get balanced coverage with Symby. See how stories are covered across diverse outlets and spot when one side covers a story the other skips.

PODCAST

Preprints in Motion

Dr Jonny Coates, Rippling Ideas

Science is experiencing a revolution. Preprints have accelerated the sharing of scientific findings and helped to make academia more equitable. Join our host, immunologist and open-science advocate, Dr Jonny Coates, as he explores the freshest science with the early career researchers who did the work; discussing their science, thoughts on academic life, publishing and much more. So sit back and join us as we dive into the fast-paced world of preprints and dismantle the outdated traditional

science life sciences

All Episodes

00:39:45

Ciliopathies, ‘Chlamy’ and Cilia length

Preprints in Motion ·

2022/07/06

This week we discuss cilia length, ciliopathies and Chlamydomonas reinhardtii (also known as ‘Chlamy’) with Brae Briggs (@BiggeBrae), a graduate student from at Dartmouth (@dartmouth),Geisel School of Medicine (@GeiselMed). We find out about a range of ciliopathies, the main composition of cilia as well as using ‘Chlamy’ as a model to study cilia length. We also discuss the difficulties of moving in the middle of a PhD and pandemic, open science principles including preprints as well as how we try

en

01:44:24

Prachee Avasthi on ASAPbio, Arcadia Science and the...

Preprints in Motion ·

2022/06/15

We’re 1 year old today! And to help celebrate our Birthday we have an extra long conversation with the incomparable Prachee Avasthi (@PracheeAC), Associate Professor at Dartmouth, President of ASAPbio and CSO & co-founder of Arcadia Science). We discuss everything from Prachee’s career journey, role in promoting preprints and open science with ASAPbio and how she came to co-found Arcadia Science. Arcadia Science: https://www.arcadiascience.com/ Arcadia Science first open house:

en

00:55:36

Can we regenerate the heart?

Preprints in Motion ·

2022/06/01

This week we discuss heart dedifferentiation and regeneration with Avraham Shakked @abingtonSA a final year PhD student, at the Weizmann Institute of Science, @WeizmannScience. We speak about their ingenious mouse model which uses transient and temporarily controlled ERBB2 expression which allows dedifferentiation and redifferentiation of cardiomyocytes. Using this model they examined the difference in RNA, protein and heart function in the redifferentiated the cells with and without heart injury

en

00:49:38

Episode 24: Baby hearts, inflammation and precarious...

Preprints in Motion ·

2022/05/17

This week we discuss placental inflammation and heart development with postdoc Eleanor Jayne Ward and PI Suchita Nadkarni (@SciSuchita) from Queen Mary, University of London. In this preprint, the authors show that during embryonic heart development, neutrophils (innate immune cells) can sometimes cause placental inflammation. This inflammation leads to a loss of barrier function. In turn, this allows maternal monocytes (innate immune cells that develop into macrophages) to migrate into the

en

00:55:29

Episode 23: Tanycyting: Characterising a neural stem...

Preprints in Motion ·

2022/05/04

This week we discuss a population of stem cells called tanycytes which line hypothalamus in the brain with Alex Moore (@alexthemessiah) an Operational Research Analyst in the Civil Service & Kavitha Chinnaiya a Post Doc from the University of Sheffield (@sheffielduni). Tanycytes are population of cells which line the 3rd ventricle in the hypothalamus, self renew and give rise to neurons and glia within the brain. We speak to them about the key findings of their paper which includes expanding on

en

00:57:18

Episode 22: Caloric Restriction: The Difference Sex...

Preprints in Motion ·

2022/04/20

CW:// This week's episode touches on some themes revolving around caloric restriction which some listeners may find difficult. This week we speak to Ben Thomas @BenThomasSci, a final year PhD student at the University of Edinburgh @EdinburghUni about the benefits of caloric restriction, the impact in male and female mice as well as the effect of age. We highlight the ingrained sexisim within the biological sciences: often only male mice are used and we discuss how this can impact the results of

en

00:53:27

Episode 21: Science in motion: How journalists’...

Preprints in Motion ·

2022/04/06

This week we discuss how journalists approach using preprints with Alice Fleerackers (@FleerackersA), a PhD student at the Simon Fraser University (@SFU). She tells us how she went behind the scenes and to examine the decision making process of journalists on whether to use preprints or not, how they contextualized the science, and what practices they use to evaluate preprints. We discuss the benefits of preprints and highlight the importance of science communication and our role as scientists to

en

00:46:43

Episode 20: Mini Brains - Organoids as 3D Brain Models

Preprints in Motion ·

2022/03/15

This week we discuss organoids and assembloids as models of neurodegenerative diseases with Sònia Sabaté Soler (@scisonias), a PhD student from the University of Luxembourg (@uni_lu). Find out about how 2D stem cells cultures are differentiated into complex 3D midbrain organoids which contain multiple cell types. We also discuss how microglia can be incorporated into the organoids to generate assembloids, mimicking the human brain more robustly. As always we speak about pre-printing and academic

en

01:12:49

Episode 19: John Inglis & Richard Sever on the...

Preprints in Motion ·

2022/03/02

A really exciting special episode this week, as we talk to co-founders of BioRxiv (@biorxivpreprint) and MedRxiv (@medrxivpreprint) Richard Sever (@cshperspectives) & John Inglis (@JohnRInglis). We discuss how they met and started with BioRxiv along with the challenges they faced. We then chat about the considerations when accepting or rejecting preprints, or why certain papers are rejected from BioRxiv (they don’t just accept everything). We also touch on the impact COVID 19 and the pandemic

en

00:46:20

Episode 18: DNA Recorders

Preprints in Motion ·

2022/02/16

This week we discuss DNA recorders with Theresa Loveless (@TheresaLovele12), a Post Doc, at UC Irvine. DNA recorders can turn transient events into stable genomic ones and have been used to investigate cell fates and lineages. Join us as we find out more about how this is achieved and the incredible technology behind it!! We also chat about Theresa’s experience of preprinting and academia, and how it can be improved!! Read the full

en

00:42:49

Episode 17: On-demand Control of Endogenous Genes

Preprints in Motion ·

2022/02/02

This week we discuss an amazing new technique developed by Dr Jakub Gemperle (@GemperleJakub), a Marie Curie Postdoctoral Research Fellow at the University of Manchester (@OfficialUoM). This technique uses 3 different inducible systems to allow on-demand control of endogenous genes, including being able to remove genes and then re-express them. A nice all in one package of techniques, great for rescue experiments!! We then also talk about Magnetogenetics where cells (and vesicles) can be moved

en

00:50:51

Episode 16: The 7 Preprints of Christmas

Preprints in Motion ·

2021/12/22

This week is our Christmas Episode! In this episode the Preprints in Motion team get together and discuss exciting, new preprints with a festive theme. We talk about smart soil, mitochondria DNA in relation to COVID 19, shock absorber stress granules as well as a discussion on nepotistic journals and much more including festive cheer and merriment. Merry Christmas and a Happy New Year from us at Preprints in Motion. Read the full

en

01:01:12

Episode 15 - The Exocyst: Somewhere between science...

Preprints in Motion ·

2021/12/01

This week we discuss the exocyst with Dr Hannes Maib @hannes_maib a Post-Doctoral Researcher at the University of Dundee @dundeeuni!! He explains the complexities of the exocyst as well as the exciting biochemistry and binding assays used to understand its formation. In addition Hannes speaks candidly about starting working in a new lab as a Post-Doc, his views of hierarchical journal systems and how preprinting can help ECR take back ownership of their work in a great discussion with our host Dr

en

00:43:07

Episode 14: Be the change you want to see:...

Preprints in Motion ·

2021/11/16

This week we discuss prefigurative politics in academia with Stefano Davide Vianello, a PhD student at @EPFL_en in Switzerland. This is the idea that in order to change how a system works we should act in a way that reflects the change we want to see. In Stefano’s case: preprinting to be the end goal and he has therefore submitted a preprint without any intention of submitting it to a journal. We speak to him about his reasons for this, why he is against academics paying for open access as well as 4

en

00:36:55

Episode 13 - Mice in Space: Characterizing Mouse...

Preprints in Motion ·

2021/11/03

This week we discuss mice in space and the impact of prolonged space flight and how this can relate to austraunoughts with Jessica L Braun @jess_l_braun a PhD Student at the Brock University @BrockUniversity. Jessica speaks about her work looking at soleus and tibialis anterior muscles of mice which have spent 35-37 days on the international space station comparing Ca2+ uptake and SERCA function. We discuss everything from a mice mission control to cardigan rhythms and the different effects on males

en

00:46:38

Episode 12 - Single Molecule Fingerprinting Reveals...

Preprints in Motion ·

2021/10/20

This week we discuss Parkinson’s Disease and single molecule spectroscopy with Dr Derrick Lau, a PostDoc at the University of New South Wales (@UNSW). Single molecular spectroscopy can be used to track the formation and purification of α-synuclein aggregates, a hallmark of PD, and potentially lead to a tool for early diagnosis of Parkinson’s Disease. We discuss how single molecular spectroscopy is transferable to medium throughput and use bio fluids for early diagnosis of Parkinson Disease but also

en

00:46:51

Episode 11 - Laterally Transferred Macrophage...

Preprints in Motion ·

2021/10/06

This week we discussed the transfer of mitochondria from macrophages to cancer cells with Dr Chelsea Kidwill & Joseph Casalin, a Post-Doctoral Research Associate and PhD student at University of Utah (@UUtah) in the school of medicine. We delve into why this transfer occurs, the mechanism of transfer and how this impacts the recipient cells. We also speak to Joseph about his alternative schooling, in addition to our usual chat about the importance of preprints and our ideas for how to improve

en

00:45:04

Episode 10 - Paywall The business of Scholarship

Preprints in Motion ·

2021/09/22

This week we discuss The Paywall Movie with Professor Jason Schmitt, chair of communication and Media at Clarkson University. We talk about academic publishing, the problems of the current system and more. In 2018, UK universities spent over £210 million on publication costs (access etc). This could have paid for; 700 ECR fellowships or 6500 postdocs or >8500 technicians or 3,500 PhDs (4yr fees + stipend). Meanwhile, Elsevier had profit margins of 37%. This week we discuss the broken publishing

en

00:47:41

Episode 09 - Incorrect Nucleotide Sequences Are...

Preprints in Motion ·

2021/09/01

This week we discuss how published nucleotide sequences are not always correct or to be trusted with Yasunori Park and Professor Jennifer A Byrne (@JAByrneSci), a research Assistant and PI at the University of Sydney (@Sydney_uni). We delve into the details of their nifty new text mining tool (Blast and Seek) which highlights papers with incorrect nucleotide sequences. We also discuss the most common mistakes found, the impact of these mistakes, and what we can do as researchers to prevent errors

en

00:51:57

Episode 08 - Identification of ACE2 modifiers by...

Preprints in Motion ·

2021/08/18

This week we discuss high throughput CRISPR/Cas9 screening and how these have been adapted to investigate novel treatments for COVID-19 with Emily Sherman a former Post Doc and Brian Emmer (@brianemmer), a new PI at University of Michigan (@UMIntMed) In this episode we cover details on how to conduct a high throughput CRISPR/Cas9 screen, the exciting advances in NextGen sequencing as well as what it's like to set up your own lab while working as a clinician during a pandemic. We also speak to Emily

en

68 results

Similar Podcasts

Classic Radio Science Fiction

solgoodmedia.com

Mission to Mars

Inception Point Ai

The 365 Days of Astronomy

365DaysOfAstronomy.org

Creek Devil

william Jevning

UFO Chronicles Podcast

Nik Hunter