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PODCAST

Core Memory

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he"s written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watched by millions and produced films for HBO and Netflix. The goal has always been to bring the tales of

technology

All Episodes

70:06

Dwarkesh Patel Wants People to Learn Things

Core Memory ·

2025/03/25

We flipped the tables on Dwarkesh Patel this week and turned the podcaster into the podcastee.Over the past few years, Patel has made a name for himself as a stellar interviewer of interesting people. Whether questioning a scientist, historian or tech engineer, Patel always goes deep with the subject and refuses to dumb things down for any audience. This is a blessing in an era of our attention being seized by 30-second blips and bloops on our phones and social apps.Patel had done a particularly

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85:10

The First Bungee Jump, Space Weapons, Lunar Landers...

Core Memory ·

2025/03/20

A few years ago, I caught wind that Sergey Brin had started funding an airship start-up called LTA (Lighter Than Air) Research.After hitting up some sources, I came to learn that the man heading up the airship venture was Dr. Alan Weston. And, after digging around some more, I came to learn that Dr. Alan Weston had lived an extraordinary life.Among many other things, Weston performed the earliest bungee jumps while a member of the Dangerous Sports Club at Oxford. He later built space weapons as part

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70:47

Max Hodak Loves Brains

Core Memory ·

2025/03/13

Few figures in Brain Computer Interface Land can match Max Hodak’s output over the past decade.He helped start Neuralink in 2016 and then went on to start Science Corp. in 2021. Science has been working on implants to help restore vision and has clinical trials underway with the technology. The company has also built out a line of brain computer interface products for others to use and is exploring some very weird and promising technology around lab-built neurons that can be infused into

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70:42

Consciousness in the Quantum Realm

Core Memory ·

2025/03/07

For the past decade, the scientist Suzanne Gildert has been working to imbue robots and AIs with new skills. She co-founded a pair of start-ups - Kindred and Sanctuary AI - that strove to add intelligence to robotic arms and bodies. The results were robotic arms that could do factory work at Kindred and then an upscaled, much weirder version of the technology at Sanctuary.In the background, Gildert spent much of her time longing to really bring robots and AIs to life. She’s been an advocate of a

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72:52

On Steve Jobs, Drugs, AI, Risk and the Enduring Magic...

Core Memory ·

2025/02/27

Don’t meet your heroes unless your hero is John Markoff. For he is as good as billed.No one has broken more stories about the technology industry or documented more of Silicon Valley’s most crucial moments than Markoff, the longtime scribe for The New York Times. He was the journalist I most wanted to model my career after, and I will remain forever jealous of all the things he witnessed first hand from the rise of semiconductors and the PC industry, to the arrival of the internet and the robotics

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58:33

Because Sometimes a Chicken Sandwich Needs to Get to...

Core Memory ·

2025/02/21

Several years ago, KFC did something ridiculous. It hired a giant, stratospheric balloon maker called World View to put its Zinger Chicken sandwich into space. Or at least near space. This was an expensive, showy endeavor and no less than Rob Lowe came on as a new Colonel Sanders-cum-Mission Control Lead for the stunt. Ultimately, the sandwich did not go quite as high as KFC wanted, but, still, I was entertained. A young man named Andrew Antonio helped drive much of World View’s marketing for the

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58:43

The Start-up Making IVF and Egg Freezing Faster and...

Core Memory ·

2025/02/13

Dina Radenkovic has set out to reshape women’s health.Gameto, her start-up based in Austin, has spent the last four years working on stem cell engineering technology that it expects to aim at things ranging from fertility treatments to menopause. On the fertility front, Gameto already has a product called Fertilo that reduces the time women must go through painful, hormonal injections from two weeks down to a couple of days. It’s been approved for use in several countries and is being studied now in

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70:56

Fly Another Day: The Daring, Thrilling, and Misguided...

Core Memory ·

2025/02/07

In this episode, we’re joined by the test pilot Elliot Seguin to learn what it’s like to put your life on the line on a regular basis. Unlike most of the people in his profession, Seguin did not do the whole Top Gun-style military training. He earned his status as a test pilot the hard way by putting in the hours flying all kinds of aircraft and convincing people to give him a go in their birds. He’s an engineer. A racer. And a brave and possibly nuts soul. We talk with Seguin about the test pilot

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67:11

Life After Extinction: Bringing Woolly Mammoths Back...

Core Memory ·

2025/01/31

Fresh off closing a $200 million funding round, Ben Lamm from Colossal Biosciences - now valued at more than $10 billion - joins Core Memory - now valued at less than $10 billion - to talk about bringing extinct animals back to our fair planet. The company has set to work on woolly mammoths, the dodo bird, and the thylacine (aka Tasmanian Tiger) in its effort to restore animals and ecosystems. To pull this off, Colossal must develop a host of gene editing technologies and artificial wombs, and we

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63:39

Keller Rinaudo Cliffton on Zipline's Drone Delivery...

Core Memory ·

2025/01/26

A few weeks ago, I went out to Zipline’s test facility in Half Moon Bay, California for a dinner and to see their delivery drones in action. I was not expecting much. It feels like we’ve been promised delivery drones for years and years. And, in fact, we have. These visions of the future don’t always arrive on schedule, but the delivery drones were feeling extra tardy. I also wasn’t even sure if delivery drones made that much sense. Drones run loud. They could obviously crash into things. It’s hard

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77:20

Joe Betts LaCroix on Longevity and Building and...

Core Memory ·

2025/01/17

Sam Altman has placed a few very large bets. There’s OpenAI, of course, and Helion Energy for fusion; World (fka Worldcoin) for finance and identity; and then Retro Bio for longevity.In late 2023, I did the first deep dive on Retro’s technology and Altman’s $180 million investment in the company. Along the way, I got to know the Retro co-founder and CEO Joe Betts-LaCroix and have spent a lot of time following Retro’s work since. Betts-LaCroix has an unusual background and an original philosophy on

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125:14

Audio: Geoff Hinton on Brains, AI and Life

Core Memory ·

2021/05/13

Here we have the dulcet sounds of neural net pioneer and all around AI guru Geoff Hinton, as interviewed by your truly. The incomparable Ryan Manning appears as host and eccentric archivist. Enjoy. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit ashleevance.substack.com

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