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PODCAST

ANA Investigates

American Neurological Association

At a time when support for basic and translational science needs a strong voice and the burden of neurological disease is growing, the ANA is the champion of neurological research and the ally of all physicians and scientists who strive to make a difference through careers that combine discovery, education, and clinical care. From advances in stroke and dementia to movement disorders and epilepsy, the American Neurological Association has been at the forefront of research and practice since 1875 as

health & fitness medicine

All Episodes

16:33

ANA Investigates Teleneurology and Healthcare Equity

ANA Investigates ·

2022/08/29

Equitable tele-neurologic care starts with first identifying disparities, then identifying how to overcome them – learn about both with Dr. Lee Schwamm on the latest ANA Investigates. Series 3, Episode 11. Featuring: Guest: Dr. Lee Schwamm, C Miller Fisher Endowed Chair in Vascular Neurology and the Director of the Center for TeleHealth at Massachusetts General Hospital, Professor of Neurology at Harvard Medical School and Vice President for Digital Patient Experience at the Mass General Brigham

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13:51

*Special Episode* ANA Investigates Potential...

ANA Investigates ·

2022/08/16

Late last month, the journal Science published an investigative report that accused a much-cited publication in Alzheimer’s disease... of fabricating scientific images. The study under scrutiny was published in Nature in 2006 by Sylvain Lesné and colleagues. It claimed that an amyloid oligomer called Aβ*56 impaired memory in mice. The recent Science report found potential fabrication in the images used in that paper... and concluded that this potential fabrication threatens the amyloid hypothesis in

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20:14

ANA Investigates Updates in Autoimmune Encephalitis,...

ANA Investigates ·

2022/07/26

Last month on the podcast, we talked about updates in the diagnosis of autoimmune encephalitis. This month we turn to advances in the treatment of autoimmune encephalitis. Treating these conditions has traditionally been practitioner-dependent, and currently no FDA-approved therapies exist. But that’s beginning to change. Series 3, Episode 9. Featuring: Guest: Dr. Maarten Titulaer, Erasmus MC University Medical Center Interviewer/Producer: Dr. Rohini Samudralwar, University of Pennsylvania

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15:10

ANA Investigates Updates in Autoimmune Encephalitis,...

ANA Investigates ·

2022/06/27

On today's episode, Dr. Adeline Goss interviews Dr. Andrew McKeon on updates on diagnostics for part one of a two-part series on autoimmune encephalitis. Series 3, Episode 8. Featuring: Guest: Andrew McKeon, M.B., B.Ch., M.D., Mayo Clinic College of Medicine and Science Interviewer/Producer: Adeline Goss, MD, Highland Hospital Disclosures: Dr. McKeon disclosed that he is a consultant for Johnson & Roche Genentech; and receives royalties from Euroimmun

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15:31

ANA Investigates TIA

ANA Investigates ·

2022/05/31

On today's episode, we discuss the term "TIA" and the current debate as it pertains to advances in stroke diagnostics that have led some to propose that we retire the term. Series 3, Episode 7. Featuring: Guest: Clay Johnston, MD, PhD, The University of Texas at Austin Interviewer/Producer: Megan Richie, MD, UCSF Disclosures: Dr. Johnston disclosed research support from AstraZeneca for the THALES trial.

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16:46

ANA Investigates Neurobiology of Burnout

ANA Investigates ·

2022/04/12

Burnt out by talking about burnout? Please join us for a podcast with Dr. Amy Arnsten, Professor of Neuroscience and Psychology at Yale University, to investigate what goes on in the brain that leads to burnout and how this can direct our efforts to reduce burnout. Series 3, Episode 6. Featuring: Guest: Dr. Amy Arnsten, Professor of Neuroscience and Psychology at Yale University - Interviewer/Producer: Dr. Amanda Jagolino-Cole of the McGovern Medical at the University of Texas Health Science

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20:46

ANA Investigates Biomarkers for Alzheimer's Disease

ANA Investigates ·

2022/03/22

On today’s show, we’ll focus on the future of biomarkers in Alzheimer’s disease. We know that amyloid beta and tau protein deposit long before patients with Alzheimer’s develop symptoms. If we could use biomarkers to detect this pathology early, and treat patients early, could we prevent the progression to dementia? Our guests today are leaders in the development of biomarkers for Alzheimer’s disease - Dr. Suzanne Schindler, Associate Professor of Neurology at Washington University in St. Louis and

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19:50

ANA Investigates Curing Coma

ANA Investigates ·

2022/02/21

Can coma be “cured”? On this podcast, we talk to Dr. Claude Hemphill and Dr. Romer Geocadin of the Curing Coma Campaign. Series 3, Episode 4 https://www.curingcoma.org/events2/world-coma-day Featuring: Guests: Romer Geocadin, MD, Johns Hopkins University & Claude Hemphill, MD, University of California San Francisco Interviewer/Producer: Dr. Adeline Goss Disclosures: None Below are articles the guests of this podcast wished to share with the listeners: Early Thalamocortical Reperfusion

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21:16

ANA Investigates Basilar Artery Stroke

ANA Investigates ·

2022/01/18

Treatment of stroke has changed dramatically in the past decade, with the advent of perfusion imaging and an expanded time window for mechanical thrombectomy. Thrombectomy is now standard of care for eligible patients. But while data clearly supports the use of thrombectomy for certain patients with anterior circulation strokes, the benefit of thrombectomy for patients with basilar artery occlusions remains unproven. Today we’ll talk to a vascular neurologist and a neurointerventional surgeon who

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17:29

ANA Investigates FND

ANA Investigates ·

2021/12/20

On today’s show we’ll focus on functional neurological disorder, or FND -- a wide range of conditions including non-epileptic seizures and functional weakness, dystonia and tremor. These conditions are common and can cause serious disability. But what are these conditions, exactly? What have functional neuroimaging and other tools taught us about their pathophysiology, diagnosis, and treatment? Series 3, Episode 2 Featuring: - Guest: Dr. Sara Finkelstein, neurologist and specialist in functional

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21:22

ANA Investigates Neurostimulation

ANA Investigates ·

2021/11/15

Some patients with medically refractory epilepsy are offered surgeries to implant devices that electrically stimulate the nervous system and actually modulate neural networks over time. On this episode of ANA Investigates, Dr. Vikram Rao of the UCSF Weill Institute for Neurosciences discusses how these neurostimulation devices can reduce seizure burden, along with a range of other potential benefits.‌ Series 3, Episode 1. Featuring: Guest: Dr. Vikram Rao, epileptologist and Associate Professor

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21:40

ANA Investigates Dysautonomia

ANA Investigates ·

2021/09/28

Autonomic dysfunction often presents with subtle symptoms affecting multiple organ systems simultaneously. On this episode of ANA Investigates, we discuss bedside evaluation and advanced workup of dysautonomia and how to manage refractory symptoms. Series 2, Episode 11. Featuring: Guest: Safwan Jaradeh, MD, Professor of Neurology, Psychiatry and Behavioral Sciences and Director of the Autonomic Disorders Program at the Stanford Neuroscience Health Center Interviewer/Producer: Megan Richie, MD,

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16:34

ANA Investigates Central Nervous System Tumor...

ANA Investigates ·

2021/08/16

In July, the World Health Organization released its updated classification of Tumors of the Central Nervous System. The last update was in 2016. The update reflects the increasing role of molecular biomarkers in tumor characterization -- a change that has major implications for how we diagnose and treat patients with brain and spinal cord tumors. Joining us today to help us understand these changes is Dr. Lynne Taylor. Dr. Taylor is a professor of Neurology and Oncology at the University of

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20:46

ANA Investigates Therapeutic Advancements in...

ANA Investigates ·

2021/07/26

In recent years, the Food and Drug Administration approved several new treatments specifically for the treatment of multiple sclerosis and neuromyelitis optica spectrum disorder. But what about neuroimmunological conditions that do not have FDA approved options and require off-label use of immunomodulatory medications -- conditions like neurosarcoidosis, neuro-Behcet’s, or central nervous system involvement of systemic rheumatologic conditions? There is often a lack of rigorous evidence to guide

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17:33

ANA Investigates Neurogenetics

ANA Investigates ·

2021/06/30

For much of the history of neurology, diagnosing a genetic disease meant giving bad news. Genetic meant incurable, often fatal. On past shows, we’ve talked about how this narrative is changing for certain monogenic diseases like Huntington’s Disease, where emerging gene therapies offer hope for a cure. But what hope can the field of neurogenetics offer to patients with more complex diseases with both genetic and environmental risk factors, like Alzheimer’s? Our guest today, Dr. M. Elizabeth Ross,

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20:35

ANA Investigates Connections between Neurology &...

ANA Investigates ·

2021/05/25

Neurology and psychiatry: two fields, one organ system. Today, we’ll focus on the intersection between the two. We’ll discuss one common psychiatric disease -- depression -- and how new treatments for depression may inform how we treat other neurologic illnesses. ANA Investigates Producer Dr. Rohit Das interviewed Dr. Helen Mayberg, behavioral neurologist at the Icahn School of Medicine at Mt. Sinai, about her pioneering research in circuit-based treatment of depression, particularly deep brain

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21:43

ANA Investigates Advancing Carotid Stenosis Treatment

ANA Investigates ·

2021/04/19

Current guidelines for management of carotid stenosis are based on a series of trials dating back to the 1990s. If you ask today’s guests, virtually no other area of neurology is so badly in need of an update. Dr. Seemant Chaturvedi, the Stewart Greenebaum Endowed Professor of Stroke Neurology at University of Maryland School of Medicine, and Dr. Cheryl Bushnell is Professor of Neurology, Vice Chair of Research, Stroke Division Chief at Wake Forest Baptist Health join us for a discussion of the

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20:28

ANA Investigates Tenecteplase in Stroke

ANA Investigates ·

2021/03/19

The topic of today’s podcast is tenecteplase. This is a thrombolytic drug that is administered intravenously, for certain patients who present to the hospital with an acute ischemic stroke. There is mounting evidence that intravenous tenecteplase is at least as safe and effective as intravenous alteplase, the current standard of care in ischemic stroke. Tenecteplase also less expensive and easier to administer. Our guest today is Dr. Bruce Campbell, who has played a pivotal role in the deployment

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14:43

ANA Investigates Detection & Management of Neurologic...

ANA Investigates ·

2021/02/15

Less than a year -- that's how long it took between when the novel coronavirus emerged and when a vaccine was available to prevent it. This incredible speed of vaccine development exemplifies scientific innovation in a time of crisis. There is increasing vaccine acceptance among the public, but questions about target populations, mechanisms, and side effects remain. Neurological complications have been documented with other vaccines, and there have been some possible complications observed with the

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17:36

ANA Investigates Neurologic Manifestations of the...

ANA Investigates ·

2021/01/18

The past year has forced us all to contend with the devastating power of infectious disease. The daily, mortal fear of infection is a new experience for many people in the developed world. But that fear characterizes life for millions of people around the globe -- including those who have already lived through plagues or lost loved ones to curable infections. These infections disproportionately target those living in poverty. Many have epidemic or pandemic potential. And many have neurological

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