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PODCAST

Evidence-Based Health Care

Oxford University

The broad aim of the Centre for Evidence Based Medicine is to develop, teach and promote evidence-based health care and provide support and resources to doctors and health care professionals to help maintain the highest standards of medicine. Many of the talks are taken from the Oxford Evidence-Based Health Care Programme and delivered by members of the Nuffield Department of Primary Care Health Sciences, the Centre of Evidence Medicine and leaders in the field of Evidence-based Health Care

education

All Episodes

33:23

Why poor diagnostic reasoning is failing patients,...

Evidence-Based Health Care ·

2019/02/06

Carl Heneghan asks the question, "What is driving the increase in diagnostic testing in healthcare?" and discusses why expectations, technology and the media are contributing to the problems of too much medicine and overdiagnosis. Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience. This talk was held as part of the Evidence-Based Diagnosis and Screening module

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48:42

Selection bias in cluster randomised controlled trials

Evidence-Based Health Care ·

2019/01/07

Professor David Torgerson, Director of the York Trials Unit, gives a talk for the Evidence Based Healthcare podcast series. He has published widely with over 250 peer reviewed papers many of them on the design of randomised trials including a student text book 'Designing Randomised Trials in Health Education and the Social Sciences' (2008, Palgrave MacMillan). He has a particular interest in the design and conduct of cluster randomised trials. Randomisation, if conducted properly, will abolish

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60:27

The application of realist approaches at the...

Evidence-Based Health Care ·

2018/12/12

Professor Mike Kelly, Primary Care Unit, Department of Public Health and Primary Care, Cambridge Institute of Public Health, University of Cambridge, gives a talk for the Evidence Based Healthcare seminar series. Professor Mike Kelly is Senior Visiting Fellow in the Department of Public Health and Primary Care at the Institute of Public Health and a member of St John's College at the University of Cambridge. Between 2005 and 2014, when he retired, he was the Director of the Centre for Public Health

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49:26

How imperfect can a study be?

Evidence-Based Health Care ·

2018/12/05

Professor Alan Silman is an epidemiologist and a rheumatologist and is the co-author of 'Epidemiological Studies: A Practical Guide', which is the recommended textbook for the module 'Introduction to Study Design and Research Methods'. Alan Silman is currently Professor of Musculoskeletal Health at the University of Oxford. He was Director of the UK's Arthritis Research Epidemiology Unit in Manchester from 1988-2006, and then Medical Director of Arthritis Research UK, before moving to Oxford to

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47:20

Adults' experiences of trying to lose weight on their...

Evidence-Based Health Care ·

2018/11/06

Jamie Hartmann-Boyce is a Senior Researcher in Health Behaviours, based at the Nuffield Department of Primary Care Health Sciences, University of Oxford. Her work focusses on obesity and tobacco control and her particular interests lie in evidence synthes Though the vast majority of people trying to lose weight do so on their own, without support from healthcare professionals or formal weight loss programmes, most research into weight loss focuses on more intensive programmes. We therefore set out

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45:52

Can antibiotics make you pregnant?

Evidence-Based Health Care ·

2018/10/29

Dr Jeffrey Aronson gives a talk for the Evidence Based Healthcare series.

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44:39

History of evidence synthesis

Evidence-Based Health Care ·

2018/10/29

Professor Mike Clarke gives a talk for the Evidence Based Healthcare series.

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36:14

Evidence-Based Manifesto for better healthcare

Evidence-Based Health Care ·

2018/10/10

Professor Carl Heneghan gives a talk for the Evidence Based Healthcare series. Patients are being let down by serious flaws in the creation, dissemination, and implementation of medical research. Too much of the resulting research evidence is withheld or disseminated only piecemeal. As the volume of clinical research activity has grown, the quality of evidence has often worsened, which has compromised medicine's ability to provide affordable, effective, high-value care for patients. Professor

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57:43

The jugglers and the black cat

Evidence-Based Health Care ·

2018/07/31

There has never been such a high demand for our personal data, such that it is often said that individuals are the product, not just the client. Using the donation of general personal data and health data in example scenarios, areas such as: the unknown element in data content; trust and trustworthiness in data custodians; and meaningful public engagement, will be explored. The alternative is that data are not used, with the corresponding harms this may bring. Ironically, this is not an unusual

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40:28

Fake surgeries and dummy pills – control for bias and...

Evidence-Based Health Care ·

2018/07/02

In this talk Karolina presented various types of study design she has used in trials of treatments for chronic pain. Karolina also discussed why blinding is important and why a placebo control may be necessary, even in surgical trials. This talk was held as part of the Introduction to Study Design and Research Methods module, which is part of the MSc in Evidence-Based Health Care.

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30:25

The shifting evidence paradigm – from literature to data

Evidence-Based Health Care ·

2018/06/26

Carol Lefebvre gives a talk for the Evidence based healthcare seminar series. Carol Lefebvre will address the shift in focus over the last 20 years away from purely ‘literature searching’, i.e. only searching databases such as MEDLINE/PubMed for published literature, such as journal articles and books for identifying studies for evidence synthesis. She will consider the ever-increasing role of unpublished data sources such as trials registers and regulatory agency sources. Carol Lefebvre is an

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42:29

Vagina Dialogues: Challenging Stigmas around...

Evidence-Based Health Care ·

2018/06/22

Communication taboos surround many aspects of women’s health and wellbeing, from menstruation to menopause to sexual pleasure. This presentation will briefly discuss the historical and socio-cultural roots of such stigmas before outlining the latest research on how these taboos come to negatively impact girls’ and women’s health. Dr Weckesser will focus on her qualitative research on endometriosis as a case study for how cultural codes of silence around menstruation play a part in the delayed

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46:58

The Replication Crisis in Biomedicine. What (kind of)...

Evidence-Based Health Care ·

2018/04/11

Professor Alexander Bird, Professor of Philosophy and Medicine, King's College London, gives a talk for the Centre for Evidenced Based Medicine. The replication (replicability, reproducibility) crisis in clinical medicine and in other fields arises from the fact that many apparently well-confirmed experimental results are subsequently overturned by studies that aim to replicate the original study. The culprit is widely held to be poor science: questionable research practices, failure to publish

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31:51

Real versus rubbish EBM: do you know the difference?

Evidence-Based Health Care ·

2018/03/02

A light hearted account of being treated by the 'wrong' guideline - with a serious conclusion about making sure this doesn’t happen. Professor Trish Greenhalgh is a Professor of Primary Care Health Sciences and the Nuffield Department of Primary Care Health Sciences. Trish Greenhalgh is an internationally recognised academic in primary health care and trained as a GP. She joined the Nuffield Department of Primary Care Health Sciences in January 2015 after previously holding professorships at

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39:59

Launch of new website to catalogue biases affecting...

Evidence-Based Health Care ·

2018/02/05

Professor Carl Heneghan and Dr David Nunan from the Oxford Centre for Evidence-Based Medicine presented the launch of a new website that catalogues the important biases affecting health and medical research. The website is in response to a call-to-arms raised nearly 40 years ago by the late David Sackett, where he called for 'The continued development of an annotated catalog of bias. Each citation should include a useful definition, a referenced example illustrating the magnitude and direction of

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39:21

Beyond accuracy: Evidence gaps and unintended...

Evidence-Based Health Care ·

2018/01/30

Point-of-care or near-patient-tests, are as these descriptors suggest, medical diagnostic tests which can be performed by a clinician, patient, or carer of a patient, without the need for samples to be transported to laboratories. These tests usually yield results rapidly, with clear convenience benefits for patients but with the potential to variably impact on clinicians. Our research suggests that evaluations of point-of-care tests usually focus on the accuracy of these tests when compared to the

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45:56

Mixed methods in the real world: a messy business?

Evidence-Based Health Care ·

2018/01/24

Dr Katherine Pollard gives a talk for the Evidence Based Healthcare seminar series. This talk focuses on mixed methods research in health care education and practice, drawing on Kathy's experience of two large mixed methods projects to demonstrate salient issues: a longitudinal evaluation of an interprofessional undergraduate curriculum and a case study of quality measurement in community nursing. Kathy discusses research design and implementation, highlighting the challenges that arose, and the

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47:13

The Future of Healthcare - Evidencer and Value Based

Evidence-Based Health Care ·

2018/01/19

Muir Gray is now working with both NHS England and Public Health England to bring about a transformation of care with the aim of increasing value for both populations and individuals. Here he gives a talk on improving healthcare systems. Here are some questions we cannot answer after nearly 70 years of a purportedly National Health Service. The lecture will address these questions and how they can be answered. 1. Is the service for people with seizures and epilepsy in Manchester of higher value than

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49:09

Life as a trial statistician – the good, the bad and...

Evidence-Based Health Care ·

2017/12/06

Professor Jonathan Cook is a Senior Medical Statistician at the Oxford Clinical Trials Research Unit. His main research interest is in the design, conduct, analysis and reporting of randomised controlled trials (particularly surgical trials). Key areas of interest include specification of the target difference in the sample size calculation, addressing interventional expertise, and methods for improving recruitment. In this light-hearted talk he discusses his experiences during his career as a trial

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41:51

How we change behaviour and what to do to support it:...

Evidence-Based Health Care ·

2017/11/28

Professor Paul Aveyard, Nuffield Department of Primary Care Health Sciences gives a talk on behavioural change in evidence based medicine. In our society, we tend to view motivation, the state of 'wanting it' as a prime mover of behaviour. However, research calls this into question both directly and by showing that, even among people with lukewarm motivation, we can enable behaviour change. Using randomised data mainly from randomised trials and other research, we will examine what these forces

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