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PODCAST

Supersized Science

Texas Advanced Computing Center - University of Texas at Austin

The Supersized Science podcast highlights research and discoveries nationwide enabled by advanced computing technology and expertise at the Texas Advanced Computing Center of the University of Texas at Austin. TACC science writer Jorge Salazar hosts Supersized Science.

science & medicine natural sciences

All Episodes

10:02

Supercomputer Helps Reveal Weaknesses in HIV-1 ‘Armor'

Supersized Science ·

2022/06/16

First realistic simulations developed of HIV-1 capsid, which encloses its genetic material.

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13:57

Cooperation Rewards Water Utilities

Supersized Science ·

2022/05/19

Inter-utility water agreements can help mitigate their risks, in research that used supercomputer simulations of water supply in the North Carolina Research Triangle.

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13:57

Cooperation Rewards Water Utilities

Supersized Science ·

2022/05/19

The Supersized Science podcast features research and discoveries nationwide enabled by advanced computing technology and expertise at the Texas Advanced Computing Center of the University of Texas at Austin. Podcast host Jorge Salazar is a science writer at TACC. Mark Twain is attributed with the quote, "Whisky is for drinking, and water is for fighting over!" But what if cooperation yielded more benefit than just going it alone, when it comes to urban water utilities? A new study of water supply

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13:10

Devil in the Coronavirus Fusion Details

Supersized Science ·

2022/05/04

Simulations suggest coronavirus fusion mechanism shows cooperative behavior of host cell receptor proteins that leads to infection. Coarse-grained models took cryo-electron tomography data and combined it with atomistic molecular dynamics simulations.

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13:10

Devil in the Coronavirus Fusion Details

Supersized Science ·

2022/05/04

The Supersized Science podcast features research and discoveries nationwide enabled by advanced computing technology and expertise at the Texas Advanced Computing Center of the University of Texas at Austin. The host is Jorge Salazar, a science writer at TACC. The details of how the SARS-CoV-2 virus infects human lung cells remains a mystery to experimental scientists. Now, the devilish details of the mechanism for fusion of the coronavirus to host cells has been revealed through simulations by

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16:12

Pioneering Simulations Focus On HIV-1 Virus

Supersized Science ·

2022/04/05

Sometimes a container isn’t just a container, not when it comes to the deadly HIV-1 virus The HIV-1 virus is wrapped in a double layer of fatty molecules called lipids that not only serves as its container but also plays a key role in HIV-1’s replication and infectivity. Scientists have used supercomputers to complete the first-ever biologically authentic computer model of the HIV-1 virus liposome, its complete spherical lipid bilayer. These results were published January 2022 in the journal PLOS

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16:12

Pioneering Simulations Focus On HIV-1 Virus

Supersized Science ·

2022/04/05

First-ever biologically authentic computer model completed of the HIV-1 virus liposome.

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17:19

Cell's Energy Secrets Revealed With Supercomputers

Supersized Science ·

2022/04/05

It takes two to tango, as the saying goes. This is especially true for scientists studying what’s inside of a cell. Protein molecules inside a cell interact with other proteins, and in a sense the proteins dance with a partner to respond to signals and regulate each other's activities. Crucial to giving cells energy for life is the migration of a compound called adenosine triphosphate or ATP, out of the cell's powerhouse, the mitochondria. And critical for this flow out to the power-hungry parts

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17:19

Cell's Energy Secrets Revealed With Supercomputers

Supersized Science ·

2022/04/05

Supercomputer simulations have revealed for the first time how the cell's mitochondrial voltage-dependent anion channel (VDAC) binds to the enzyme hexokinase-II (HKII).

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21:12

Into the Vortex

Supersized Science ·

2022/04/01

Vortex dynamics simulations reveal reconnection, an important property linked with creation of turbulence cascade, fluid mixing, and aerodynamic noise generation.

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21:12

Into the Vortex

Supersized Science ·

2022/04/01

Scientists are looking deeper into the mysterious characteristics of vortexes and turbulence, in recent studies by Texas Tech University scientists that used the Frontera, Stampede2, and Lonestar5 supercomputers here at TACC, allocated through the Extreme Science and Engineering Discovery Environment, funded by the National Science Foundation. A possible application of the Texas Tech vortex research could help improve fuel efficiency for cars and help develop energy-saving aircraft designs, and

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16:05

Hawaiian Emperor Undersea Mystery Revealed With...

Supersized Science ·

2022/03/31

The Hawaiian-Emperor seamount chain spans almost four thousand miles from the Hawaiian Islands to the Detroit Seamount in the north Pacific, an L- shaped chain that goes west then abruptly north. The 60-degree bend in the line of mostly undersea mountains and volcanic islands has puzzled scientists since it was first identified in the 1940s from the data of numerous echo sounding ships. A team of scientists have now used supercomputers to model and reconstruct the dynamics of Pacific tectonic plate

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16:05

Hawaiian Emperor Undersea Mystery Revealed With...

Supersized Science ·

2022/03/31

Kinematic plate reconstructions and high-res global dynamic models developed to quantify the amount of Pacific Plate motion change associated with the Hawaiian– Emperor Bend XSEDE allocations on TACC Stampede2; NSF-funded Frontera supported studies.

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31:34

Supercomputers Help Reveal Dynamic Plastic-Eating Duo

Supersized Science ·

2021/12/10

Plastic waste is a big problem in the environment. About 300 million tons of plastic waste are produced every year, according to the United Nations. Much of that is polyethylene terephthalate (PET), a plastic in single-use bottles, carpets, and clamshell packaging. In the U.S., the Environmental Protection Agency estimates annually that only about 29 percent of PET bottles are recycled. In 2016, Japanese scientists discovered that the bacteria Ideonella sakaiensis had evolved digestive enzymes

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31:34

Supercomputers Help Reveal Dynamic Plastic-Eating Duo

Supersized Science ·

2021/12/10

NREL scientists discover synergy in PET plastic-degrading enzymes using TACC, SDSC resources

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21:09

What Happens When A Meteor Hits The Atmosphere?

Supersized Science ·

2021/11/05

XSEDE-allocated Stampede2 supercomputer simulations shed light on meteor physics

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21:09

What Happens When A Meteor Hits The Atmosphere?

Supersized Science ·

2021/11/05

The Supersized Science podcast hosted by science writer Jorge Salazar features research and discoveries enabled by advanced computing technology and expertise of the Texas Advanced Computing Center of the University of Texas at Austin. High above your head right now, it's raining dirt. Day or night, every second, millions of pieces of dirt that are smaller than a grain of sand strike Earth's upper atmosphere. At an altitude of about 100 kilometers, bits of dust, mainly debris from asteroid

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25:17

Getting To The Core Of HIV Replication

Supersized Science ·

2021/04/01

HIV-1 viral capsid simulations on XSEDE-allocated Stampede2, Bridges, Darwin systems uncover nucleotide entry mechanism

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25:17

Getting To The Core Of HIV Replication

Supersized Science ·

2021/04/01

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. Viruses needs a host cell. And through infection, they hijack it and force it to make copies of itself. Supercomputer simulations have helped uncover the mechanism for how the HIV-1 virus imports into its core the nucleotides it needs to fuel DNA synthesis, a key step in its replication. It's the first example found where a virus performs

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15:41

Complete Coronavirus Model

Supersized Science ·

2021/03/04

Frontera, Anton 2 supercomputers simulate holistic model of SARS-CoV-2 virion

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221 results

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