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PODCAST

This Week in Parasitism

Vincent Racaniello

TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.

science life sciences

All Episodes

01:12:40

TWiP 236: Prime-and-trap vaccine for malaria

This Week in Parasitism ·

2024/06/01

Marion Avril of MalarVx, Inc. joins TWiP to discuss an accelerated prime-and-trap regimen using repRNA-based circumsporozoite vaccine. Hosts: Dickson Despommier and Christina Naula Guest: Marion Avril Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute repRNA-based CSP malaria vaccine (NPJ vaccines) Hero: Mwelecele Ntuli Malecela Become a patron of TWiP Send your guesses

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01:15:38

TWiP 235: The case of the regurgitated wriggler

This Week in Parasitism ·

2024/05/17

TWiP solves the case of a man in his 50s reporting months of abdominal discomfort, who takes mebendazole and some time afterwards vomits a worm into the sink. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute The giant intestinal worm, Ascaris lumbricoides (TWiP 21) Parasitic Diseases Lectures

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01:22:35

TWiP 234: Hookworms and a leech - parasites suck!

This Week in Parasitism ·

2024/05/04

TWiP discusses hookworm infection and the phase 1 clinical trial for a hookworm vaccine that could one day protect children from the hookworm anaemia, and reduce transmission of this infection. Hosts: Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute Hookworm vaccines in school-aged children in Gabon (Lancet Inf Dis) Step

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01:20:43

TWiP 233: Cryptosporidium not cryptocurrency

This Week in Parasitism ·

2024/04/19

TWiP solves the case of the physician with no significant previous medical history who is currently doing their fellowship training develops diarrhea, and presents a new clinical case for our astute listeners to solve. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute Hero: Keith Vickerman Letters

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53:50

TWiP 232: Lives of Wolbachia

This Week in Parasitism ·

2024/04/05

TWiP reviews the cellular lives of Wolbachia, a gram-negative bacteria that infects many arthropods and filarial nematodes with very different outcomes – parasitism or mutualism. Hosts: Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute Cellular lives of Wolbachia (Nat Rev Micro) Hero: Patricia F. Walker Become a patron of

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55:59

TWiP 231: Scotch in drink and tape

This Week in Parasitism ·

2024/03/31

TWiP solves the case of the Woman With White Worms, and presents a new clinical case to decipher. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Please support our work at microbe.tv/contribute Hero: Ann Bishop Become a patron of TWiP New Case study: A physician with no significant PMH who is currently doing their fellowship training develops

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01:00:47

TWiP 230: Healing cutaneous leishmaniasis with Maria...

This Week in Parasitism ·

2024/03/01

Maria Adelaida Gomez joins TWiP to discuss her career and the work of her laboratory on understanding the healing process during cutaneous leishmaniasis. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guest: Maria Adelaida Gomez Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode CIDEIM Healing in cutaneous leishmaniasis (J Immunol) Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald

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01:02:53

TWiP 229: The very hungry flatworm

This Week in Parasitism ·

2024/02/27

Eyal joins TWiP to solve the case of the Female Traveler with Intermittent Fever and Ring Enhancements in the Liver. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guest: Eyal Leshem Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Become a patron of TWiP Case Study for TWiP 229 Woman in her 40s is referred to me to be seen in the office from one of my colleagues. She reports that she has been having recurrent issues with worms

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01:08:48

TWiP 228: Parasitic fountain of youth

This Week in Parasitism ·

2024/02/06

TWiP discusses a tapeworm that causes extreme lifespan extension in infected ant workers, and a candidate antibody drug for prevention of malaria. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Extreme lifespan extension in tapeworm-infected ant workers (Roy Soc Open Sci) Candidate antibody drug for prevention of malaria Ceilidh goes viral (YouTube) Become a patron of TWiP Send

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01:38:53

TWiP 227: Alpha-gal syndrome

This Week in Parasitism ·

2024/01/20

Jim Small joins TWiP to solve the case of the 41 year old Man with sudden GI distress and itchy hives, followed by a discussion of parasites and childhood stunting. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guest: Jim Small Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Parasites and childhood stunting (Trends Parasitol) Letters read on TWiP 227 Become a patron of TWiP Send your questions and comments to twip@microbe.tv

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01:23:18

TWiP 226: Successful systems attract parasites

This Week in Parasitism ·

2024/01/03

TWiP reviews some parasite stories of 2023, including progress in the control of malaria and polio, and review a connection between parasites and childhood stunting. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Second malaria vaccine (Nature) Malaria report 2023 (WHO) Malaria and climate change (WHO) Parasites and childhood stunting (Trends Parasitol) Sea creature spotted off

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01:24:53

TWiP 225: Wandering worm with Lee Gottesdiener

This Week in Parasitism ·

2023/12/20

Lee Gottesdiener joins TWiP to help solve the case of the 46 Year Old Man with Ongoing Upper Extremity Swelling, and review plant‑based production of a protective vaccine antigen against the bovine parasitic nematode Ostertagia ostertagi. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Vaccine against cow parasite (Vert Farm Daily) Protective vaccine against bovine parasitic

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57:54

TWiP 224: Neglected tropical diseases roadmap with...

This Week in Parasitism ·

2023/12/12

Chuck Knirsch returns to TWiP to discuss the Neglected Tropical Diseases Roadmap published by WHO, which sets global targets and milestones to prevent, control, eliminate or eradicate 20 diseases and disease groups. Chuck Knirsch returns to TWiP to discuss the Neglected Tropical Diseases Roadmap published by WHO, which sets global targets and milestones to prevent, control, eliminate or eradicate 20 diseases and disease groups. Hosts: Vincent Racaniello, Dickson Despommier, and Chuck Knirsch

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01:27:47

TWiP 223: Voluminous diarrhea

This Week in Parasitism ·

2023/11/28

TWiP solves the case of the Haitian female with AIDS and voluminous diarrhea, and review the pathogenesis, epidemiology, prevention and treatment of malaria and Chagas disease. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Click arrow to play Download TWiP #223 (63 MB .mp3, 88 minutes) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Malaria (Lancet) Chagas disease (AJTMH) Hero: Joe Cook Letters read on TWiP 223 Become

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01:08:01

TWiP 222: Balamuthia in the brain with Natasha...

This Week in Parasitism ·

2023/10/31

At the meeting of the American Society for Tropical Medicine and Hygeine in Chicago, Natasha joins TWiP to solve the case of the Man with a Generalized Seizure and Infectious Forms in the Brain. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guest: Natasha Spottiswoode Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Treatment of Balamuthia encephalitis with nitroxoline (Emerg Inf Dis) Letters read on TWiP 222 Become

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01:23:19

TWiP 221: Delusional parasitosis

This Week in Parasitism ·

2023/10/01

Michelle and Alexander join TWiP to solve their case of the 36 Year Old Male with shortness of breath, stinging pain in the extremities, fatigue, abdominal cramps, and bowel irregularities, and discuss host cell invasion by Trypanosoma cruzi. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guests: Michelle Naegeli and Alexander Grieb Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode cAMP-dependent invasion by Trypanosoma

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01:36:41

TWiP 220: Denies any bug bites

This Week in Parasitism ·

2023/08/20

TWiP solves the case of the Hiker from Queens who Denies Bug Bites, and reveal two different malaria experimental vaccines that target different parts of the parasite life cycle. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Malaria transmission-blocking vaccine (Lancet Inf Dis) mRNA vaccine against malaria (Nat Immunol) Letters read on TWiP 220 Become a patron of TWiP Case

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01:03:53

TWIP 219: Sick as a dog

This Week in Parasitism ·

2023/07/24

TWiP solves the case of the 19 month old Female Having Issues, and discusses the finding that selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles mosquitoes. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Insecticide resistance in mosquitoes promotes Plasmodium infection (PLoS Path) Letters read on TWiP 219 Become a patron of TWiP Case

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01:21:59

TWiP 218: Malaria parasite evades mosquito

This Week in Parasitism ·

2023/06/29

TWiP solves two cases this week, the Man with Issues after COVID-19, and the Man with Left Arm Weakness, then describe how the malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Malaria parasite evades mosquito immunity (Proc Natl Acad Sci USA) Letters read on TWiP 218 Become a patron of

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01:27:37

TWiP 217: ChatGPT solves the case

This Week in Parasitism ·

2023/06/05

TWiP solves the case of the Man With Dog Exposure, and discuss rapid and spontaneous post-partum clearance of Plasmodium falciparum related to expulsion of the placenta. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Post-partum clearance of P. falciparum (J Inf Dis) Letters read on TWiP 217 Become a patron of TWiP Case Study for TWiP 217 We have two cases today! A man in his 60s who provides IT

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