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PODCAST

The Peter Attia Drive

Peter Attia, MD

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

health & fitness medicine

All Episodes

02:08:48

#26 - AMA #3: supplements, women’s health, patient...

The Peter Attia Drive ·

2018/10/29

In this “Ask Me Anything” (AMA) episode, Peter answers a wide range of questions from readers and podcast listeners. Bob Kaplan, Peter’s head analyst, asks the questions. This also marks the first video release of the podcast. You can find it on YouTube (https://youtu.be/kzs7GgxR_FQ) and the website (peterattiamd.com/ama03). If you have any questions for the next AMA, please submit them to the AMA section on the website (peterattiamd.com). We discuss: What references ranges does Peter consider too

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02:18:40

#25 - Scott Harrison: transformation, finding...

The Peter Attia Drive ·

2018/10/22

We discuss: How Scott and Peter met [3:45]; Scott’s tragic family story that shaped his life and altered his trajectory [8:00]; High school years, rebellion, and music [30:30]; Life as a club promoter, drug use, soul-searching, and a change of heart [41:30]; Mercy Ships [1:15:00]; The amazing transformations of Mercy Ships and the parallels to his own transformation [1:28:00]; Leveraging the art of storytelling to raise money and awareness while fighting temptations to fall into his previous life

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01:29:39

#24 - Tom Dayspring, M.D., FACP, FNLA – Part V of V:...

The Peter Attia Drive ·

2018/10/19

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part V, Peter and Tom talk about inflammation, endothelial health, and oxidative stress as they pertain to cardiovascular disease, and our attempts to monitor them using biomarkers. They also discuss a couple of very important risk factors that too few people (and doctors) know about. Tom

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02:00:05

#23 - Tom Dayspring, M.D., FACP, FNLA – Part IV of...

The Peter Attia Drive ·

2018/10/18

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part IV, Peter and Tom review the history and current use of drugs to prevent cardiovascular disease. They also discuss why some drugs appear to be more effective than others, an in-depth conversation about niacin, cholesterol and brain health, and the futility of using CKs (creatinine

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01:04:13

#22 - Tom Dayspring, M.D., FACP, FNLA – Part III of...

The Peter Attia Drive ·

2018/10/17

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part III, Peter and Tom dig into HDL, why "reverse cholesterol transport" is a lot more nuanced than what most of us are taught, lipid transport, apolipoproteins, and more. In addition, this episode highlights the complexity of HDL and a discussion about the CETP inhibitor trials. We

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01:26:55

#21 - Tom Dayspring, M.D., FACP, FNLA – Part II of V:...

The Peter Attia Drive ·

2018/10/16

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part II, Tom provides a 101 on lipids and lipoproteins. Tom and Peter also discuss the history and techniques used to measure lipoproteins, and more. We discuss: Lipoprotein basics [1:30]; Gofman and the ultracentrifuge [5:15]; Lipoprotein structure, function, metabolism [6:45];

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01:14:28

#20 - Thomas Dayspring, M.D., FACP, FNLA – Part I of...

The Peter Attia Drive ·

2018/10/15

In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. Part I serves as an introduction to Tom, his work, and an overview of lipid terminology. We discuss: Tom’s recent and remarkable physical transformation [6:30]; The moving stories behind Tom’s obsessions: firefighting, hockey, and, of course, lipids [20:30]; Tom’s medical background [39:30];

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03:10:16

#19 - Dave Feldman: stress testing the lipid energy...

The Peter Attia Drive ·

2018/10/08

In this episode, Dave Feldman, discusses his journey from software engineer to n=1 experimenter, his experience with low-carbohydrate diets, and his hypothesis that cholesterol levels are influenced by energy metabolism. We discuss: Peter’s synthesis of Dave’s energy model [5:00]; Dave’s journey from software engineer to cholesterol enthusiast [15:00]; Standard blood panels, sterol panels, and what moves the needle when it comes to particle numbers [18:30]; Hyper-responders [20:00]; Lipoprotein

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02:24:18

#18 - Richard Isaacson, M.D.: Alzheimer’s prevention

The Peter Attia Drive ·

2018/10/01

In this episode, Richard Isaacson, a neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, discusses strategies for staving off Alzheimer’s disease. Richard shares a wealth of insight for people who want to know more about Alzheimer’s and what you can do to help yourself and your loved ones – starting today and continuing throughout the entire lifespan. We discuss: Richard’s fun-facts (and alter egos): “bling” phones, Doogie Howser, and

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01:56:06

#17 - Mike Trevino: life-lessons from...

The Peter Attia Drive ·

2018/09/24

In this episode, ultra-endurance athlete and entrepreneur, Mike Trevino, discusses the lessons he’s learned from his remarkable athletic feats, and the training required to reach them. Not only is Mike’s advice practical for those looking to take their endurance training to the next level, but his lessons and insight are extraordinarily applicable to living everyday life. We discuss: Mike’s background, his crazy birthday tradition, and his transition from power to endurance [6:30]; Mike’s

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01:03:10

#16 - Formula 1 (with Paul Conti): the best drivers,...

The Peter Attia Drive ·

2018/09/20

In this bonus episode, Peter and med school colleague (and brilliant psychiatrist) Paul Conti reminisce on their favorite moments in Formula 1 history, their deep admiration for the late Ayrton Senna, and the remarkable careers of their all-time favorite drivers. Paul also helps to illuminate the psychological components that made the luminary drivers great, and the cautionary lessons we can take from their incredible lives. We discuss: Ayrton Senna [3:45]; How Senna’s death changed the sport

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02:09:13

#15 - Paul Conti, M.D.: trauma, suicide, community,...

The Peter Attia Drive ·

2018/09/17

In this episode, psychiatrist Paul Conti, M.D. discusses the impact of untreated trauma, the rising rate of suicide, and the influence of modern society on mental health, to name a few important topics covered. Paul also talks about how to deal with these challenges for yourself, your loved ones, and the community at large. We discuss: Paul’s background, and what drove him to psychiatry [5:00]; How silent bravado and incessant striving can lead to a functional (and actual) death, and why Paul is

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01:23:17

#14 - Robert Lustig, M.D., M.S.L.: fructose,...

The Peter Attia Drive ·

2018/09/10

In this episode, Rob Lustig — a researcher, an expert in fructose metabolism, and a former pediatric endocrinologist — discusses what’s wrong with the current food environment, and what we can do to reduce our chances of becoming part of the obesity, diabetes, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) epidemics. Rob recently earned a Master of Studies in Law because he believes that educating people about sugar from a scientific standpoint is only half the equation: the other

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01:48:42

#13 - Brett Kotlus, M.D.: How to look younger while...

The Peter Attia Drive ·

2018/09/03

This episode explores the question of how we can maintain a naturally youthful look as we get older. Brett — a New York City oculofacial plastic surgeon who specializes in both non-surgical and surgical cosmetic and reconstructive procedures of the eyes and face — shares some remarkably practical advice on everything from the most extensive procedural options, down to the simple steps one can do themselves, starting today, that can make a tremendous impact. Brett also discusses how to pick a

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02:27:00

#12 - Corey McCarthy: Overcoming trauma, dealing with...

The Peter Attia Drive ·

2018/08/27

Corey and Peter met when they visited North Kern State Prison in California together as volunteers for Defy Ventures. Peter was moved by Corey’s remarkable story, who is a former inmate himself, and realized he had to have him on the podcast to share his experiences with a wider audience. You’ll almost assuredly take away something very important from listening to this episode. Understanding how your experiences can define you, what forgiveness means of both yourself and others, and how good people

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01:50:33

#11 - AMA #2: the Nothingburger — results from...

The Peter Attia Drive ·

2018/08/23

Consider this episode a cross between an ask me anything (AMA) and a show-and-tell. Peter discusses his fasting experiment in great detail and answers questions from listeners and readers. We discuss: Why Peter did a one-week fast and the rationale for front- and back-ending it with a week-long ketogenic diet [6:30]; What Peter’s typical diet, exercise, sleep, stress management, and supplementation looks like [11:00]; What labs (e.g., glucose, ketones, lipids, inflammation and oxidation markers,

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01:32:45

#10 - Matt Kaeberlein, Ph.D.: rapamycin and dogs —...

The Peter Attia Drive ·

2018/08/20

Matt is someone who is deeply interested in understanding the biology of aging. Why do we age? What happens to us as we age? What are the things we can do to slow the aging process? How can we delay or prevent the onset of age-related diseases? These are all questions that Matt thinks deeply about, and explores these questions with his research at the University of Washington. He is currently investigating many of these questions through the Dog Aging Project and the compound rapamycin—the only

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01:11:22

#09 - David Sabatini, M.D., Ph.D.: rapamycin and the...

The Peter Attia Drive ·

2018/08/13

In this episode, my good friend David Sabatini delves into his extensive work with the mechanistic target of rapamycin—better known as mTOR—and rapamycin. The compound rapamycin is the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. David, a professor of biology and a member of the Whitehead Institute at MIT, shares his remarkable journey and discovery of mTOR in mammalian cells and its central role in nutrient sensing and

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01:38:13

#08 - Tom Bilyeu: nutrition, fasting, meditation,...

The Peter Attia Drive ·

2018/08/06

Tom Bilyeu is the founder of Impact Theory and a co-founder of Quest Nutrition. In this episode, among the highlights, Tom provides powerful insight he’s gained through his pursuit of fulfillment which led to a billion-dollar company in Quest Nutrition. Tom makes a compelling case that it starts with a growth mindset and he’s determined to impart this knowledge into as many people as possible. We discuss: Tom’s history with dieting and his changing views on fat [4:00]; Tom’s dream of immortality

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01:16:09

#07 - Deep Dive: Lp(a) — what every doctor, and the...

The Peter Attia Drive ·

2018/07/30

Pronounced, el-pee-little-a, this lipoprotein is simply described as a low density lipoprotein (LDL) that has an apoprotein “a” attached to it...but Lp(a) goes far beyond its description in terms of its structure, function, and the role that it plays in cardiovascular health and disease. Affecting about 1-in-5 people, and not on the radar of many doctors, this is a deep dive into a very important subject for people to understand. A quick primer on lipoproteins [7:30]; Intro to Lp(a) [11:00]; Lab

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