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PODCAST

Empowered Patient Podcast

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

health & fitness medicine

All Episodes

0:00

Personalized T-Regulatory Cell Therapy for Type-1...

Empowered Patient Podcast ·

2024/12/04

Professor Piotr Trzonkowski, CEO of PolTREG, is focused on developing cell therapies for autoimmune diseases like type-1 diabetes and multiple sclerosis using polyclonal T-regulatory cell therapy. Treg cells are key in regulating the immune system and preventing autoimmune diseases. Clinical trials are showing promise for safe and effective treatments for preventing type-1 diabetes in pre-symptomatic patients and maintaining insulin production for years after treatment in those with this form of

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20:19

Personalized T-Regulatory Cell Therapy for Type-1...

Empowered Patient Podcast ·

2024/12/04

Professor Piotr Trzonkowski, CEO of PolTREG, is focused on developing cell therapies for autoimmune diseases like type-1 diabetes and multiple sclerosis using polyclonal T-regulatory cell therapy. Treg cells are key in regulating the immune system and preventing autoimmune diseases. Clinical trials are showing promise for safe and effective treatments for preventing type-1 diabetes in pre-symptomatic patients and maintaining insulin production for years after treatment in those with this form of

en

0:00

Strategies to Strengthen Healthcare Cybersecurity and...

Empowered Patient Podcast ·

2024/12/04

Cecil Pineda, Senior VP and Chief Information Security Officer at R1 RCM, is focused on integrating robust cybersecurity into the revenue cycle management process. When healthcare organizations are hit with ransomware attacks, they must respond rapidly and accurately communicate with internal and external partners. Long-term strategies include controlling network access, backup/recovery testing and educating personnel in order to limit damage from attempts to invade the network. Cecil explains,

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19:58

Strategies to Strengthen Healthcare Cybersecurity and...

Empowered Patient Podcast ·

2024/12/04

Cecil Pineda, Senior VP and Chief Information Security Officer at R1 RCM, is focused on integrating robust cybersecurity into the revenue cycle management process. When healthcare organizations are hit with ransomware attacks, they must respond rapidly and accurately communicate with internal and external partners. Long-term strategies include controlling network access, backup/recovery testing and educating personnel in order to limit damage from attempts to invade the network. Cecil explains,

en

0:00

Seeking Brain Donations to Advance Research and...

Empowered Patient Podcast ·

2024/12/03

David explains, "We went to the Simons Foundation and, with their support, have established a network in the United States. We have three collection sites: one at the UC Davis Mind Institute in Sacramento, one at UT Southwestern in Dallas, Texas, and one at the Mass General Hospital in Boston, where a postmortem brain donation can be sent. Those brains are then prepared in ways that will facilitate all kinds of research both now and in the future. We have developed this resource to foster autism

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28:14

Seeking Brain Donations to Advance Research and...

Empowered Patient Podcast ·

2024/12/03

This is a conversation with Dr. David Amaral, a distinguished professor at the MIND Institute and scientific director of Autism BrainNet, and Dorothy Frisch, an activist and supporter of the program. Autism BrainNet is funded by the Simons Foundation to collect and study postmortem brain samples from individuals with autism to understand the neurological basis of the disorder better. Currently, there are no biomarkers for autism, so studying the brains and accomplishments of those who had autism can

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0:00

Raising Thiamine Levels in the Brain to Treat Early...

Empowered Patient Podcast ·

2024/12/02

Dr. Jose Luchsinger, Vice Chair for Clinical and Epidemiologic Research at Columbia University, is leading a phase 2 clinical trial of a prodrug Benfo that aims to raise the level of thiamine in the brain to improve memory and function in people with early Alzheimer's disease. This effort is based on research showing that Alzheimer's is associated with impaired thiamine processing in the brain, even if thiamine levels in the blood are normal. The phase 2 clinical trial for the drug is testing the

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25:07

Raising Thiamine Levels in the Brain to Treat Early...

Empowered Patient Podcast ·

2024/12/02

Dr. Jose Luchsinger, Vice Chair for Clinical and Epidemiologic Research at Columbia University, is leading a phase 2 clinical trial of a prodrug Benfo that aims to raise the level of thiamine in the brain to improve memory and function in people with early Alzheimer's disease. This effort is based on research showing that Alzheimer's is associated with impaired thiamine processing in the brain, even if thiamine levels in the blood are normal. The phase 2 clinical trial for the drug is testing the

en

0:00

AI-Powered Tools Save Physicians Time and Enhance ...

Empowered Patient Podcast ·

2024/11/26

Dr. Michael Sherling, Co-Founder, Chief Medical Officer, and Strategy Officer at ModMed, aims to save time for physicians and patients by reducing administrative burden through technology. Their AI-based solutions focus on automating mundane tasks like fax routing and documentation and can passively transcribe doctor-patient conversations to generate structured notes. The interface is designed to be simple and unobtrusive, minimizing extra clicks or steps for the doctors to review and accept the

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20:37

AI-Powered Tools Save Physicians Time and Enhance ...

Empowered Patient Podcast ·

2024/11/26

Dr. Michael Sherling, Co-Founder, Chief Medical Officer, and Strategy Officer at ModMed, aims to save time for physicians and patients by reducing administrative burden through technology. Their AI-based solutions focus on automating mundane tasks like fax routing and documentation and can passively transcribe doctor-patient conversations to generate structured notes. The interface is designed to be simple and unobtrusive, minimizing extra clicks or steps for the doctors to review and accept the

en

0:00

Antibody Drug Targets Toxic Amyloid Oligomers from...

Empowered Patient Podcast ·

2024/11/25

Dr. Eric Siemers, Medical Officer at Acumen Pharma, is developing a monoclonal antibody called sabirnetug that targets a specific toxic form of amyloid beta, Aβ oligomers. These oligomers are now believed to be a key driver of neuronal damage in Alzheimer's disease. The drug is in phase 2 clinical trials to evaluate its ability to slow cognitive decline in early-stage Alzheimer's patients and demonstrate the accuracy of biomarkers in identifying pathology before symptoms appear. Eric explains,

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22:31

Antibody Drug Targets Toxic Amyloid Oligomers from...

Empowered Patient Podcast ·

2024/11/25

Dr. Eric Siemers, Medical Officer at Acumen Pharma, is developing a monoclonal antibody called sabirnetug that targets a specific toxic form of amyloid beta, Aβ oligomers. These oligomers are now believed to be a key driver of neuronal damage in Alzheimer's disease. The drug is in phase 2 clinical trials to evaluate its ability to slow cognitive decline in early-stage Alzheimer's patients and demonstrate the accuracy of biomarkers in identifying pathology before symptoms appear. Eric explains,

en

0:00

Integrating the Patient Perspective in Defining and...

Empowered Patient Podcast ·

2024/11/25

Rob Abbott, CEO and Executive Director at ISPOR, the Professional Society for Health Economics and Outcomes Research, focuses on defining and measuring value in healthcare, including accessibility, affordability, effectiveness, and patient outcomes. HEOR (health economics and outcomes research) can provide data-driven insights to guide healthcare decision-making, reduce bias in research, and consider a broader range of factors like social determinants of health. This can improve treatment

en

17:21

Integrating the Patient Perspective in Defining and...

Empowered Patient Podcast ·

2024/11/25

Rob Abbott, CEO and Executive Director at ISPOR, the Professional Society for Health Economics and Outcomes Research, focuses on defining and measuring value in healthcare, including accessibility, affordability, effectiveness, and patient outcomes. HEOR (health economics and outcomes research) can provide data-driven insights to guide healthcare decision-making, reduce bias in research, and consider a broader range of factors like social determinants of health. This can improve treatment

en

0:00

Identification of Genetic Biomarker Leads to...

Empowered Patient Podcast ·

2024/11/22

Tony Goodman is the Chief Operating Officer at Adial Pharmaceuticals, which is developing a personalized therapy for alcohol use disorder based on a genetic biomarker. This unique approach combines the therapeutic AD04 with the biomarker AG Plus to identify a specific AUD patient population that responds well to this drug. Insights from this work could potentially lead to a broader understanding of the genetic and neurobiological connection underlying addiction. Tony explains, "What makes us

en

22:47

Identification of Genetic Biomarker Leads to...

Empowered Patient Podcast ·

2024/11/22

Tony Goodman is the Chief Operating Officer at Adial Pharmaceuticals, which is developing a personalized therapy for alcohol use disorder based on a genetic biomarker. This unique approach combines the therapeutic AD04 with the biomarker AG Plus to identify a specific AUD patient population that responds well to this drug. Insights from this work could potentially lead to a broader understanding of the genetic and neurobiological connection underlying addiction. Tony explains, "What makes us

en

0:00

Computational AI Bringing Predictability Precision to...

Empowered Patient Podcast ·

2024/11/21

Shai Shen-Orr, the Co-Founder and Chief Scientist of CytoReason, is developing computational disease models powered by AI to improve the probability of success in phase 2 clinical trials. Their goal is to more precisely develop drugs using AI to analyze large amounts of biological and clinical data and overcome the challenges of the complexity and uncertainty in medical information. Working with large pharmaceutical companies, CytoReason is supporting companies in their drug development efforts and

en

21:13

Computational AI Bringing Predictability Precision to...

Empowered Patient Podcast ·

2024/11/21

Shai Shen-Orr, the Co-Founder and Chief Scientist of CytoReason, is developing computational disease models powered by AI to improve the probability of success in phase 2 clinical trials. Their goal is to more precisely develop drugs using AI to analyze large amounts of biological and clinical data and overcome the challenges of the complexity and uncertainty in medical information. Working with large pharmaceutical companies, CytoReason is supporting companies in their drug development efforts and

en

0:00

Food as Medicine Platform Offers Personalized...

Empowered Patient Podcast ·

2024/11/20

Josh Hix, the CEO of Season Health, has developed a food as medicine platform that combines registered dietitian services, food delivery, and medical nutrition therapy. This makes it easier for patients to access food benefits and eat healthier. The rise of GLP-1 agonist medications for weight management has highlighted the need to develop personalized nutrition plans to help patients maintain a healthy lifestyle. There is growing interest in food as medicine as it is increasingly recognized that

en

19:27

Food as Medicine Platform Offers Personalized...

Empowered Patient Podcast ·

2024/11/20

Josh Hix, the CEO of Season Health, has developed a food as medicine platform that combines registered dietitian services, food delivery, and medical nutrition therapy. This makes it easier for patients to access food benefits and eat healthier. The rise of GLP-1 agonist medications for weight management has highlighted the need to develop personalized nutrition plans to help patients maintain a healthy lifestyle. There is growing interest in food as medicine as it is increasingly recognized that

en

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