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PODCAST

cc: Life Science Podcast

How will AI, CRISPR, CGT and other new technologies impact life science? I"m following my curiosity. Follow along with me. cclifescience.substack.com

science life sciences

All Episodes

31:27

What Can You Do with 3.5 Million (de-identified)...

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2023/02/22

It turns out, you can do quite a lot.Jud Schneider is the CTO of Nashville Biosciences. I reached out to him to talk about their collaboration with Amgen and Illumina to sequence 35,000 African-American genomes. How is that possible?Nash Bio (owned by Vanderbilt University Medical Center) has about three and a half million de-identified health records. About 10% of those have consented DNA tied to those records. This is a treasure trove of data for pharma and AI companies to uncover patterns and

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38:08

A Conversation About ChatGPT

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2023/02/01

ChatGPT has become the AI that is impossible to ignore. As I wrote in my first post a little more than a year ago, I would be neither a cheerleader nor a detractor, but rather a curious observer. So here we are. My main concern with respect to many technologies is the dilution of our humanity. In response to all the posts I was seeing where people were asking ChatGPT to create content, I wrote on LinkedIn that the value of your voice, even better with your face attached to it, would increase. The

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36:39

What is FAIR Data and Why is it Important?

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2023/01/18

Mark Fortner, Founder and CEO of Aspen Biosciences joined to explain the concept of FAIR data. The idea around FAIR data is to ensure that data is available and labeled consistently to allow people AND machines to correctly interpret, for example, what the label on a column of data means. The benefit for all is to enable more effective data sharing in collaborations or over time from one study to another.Mark provided the following summary for me.We can take the FAIR acronym as a laundry list of

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26:09

Digital Health and Business Model Innovation

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2023/01/04

I talked to Jason Scharf about new business models and digital health to get a glimpse of where the world of life science and healthcare are going. Jason is the host of the Austin Next Podcast. He has been an operator at companies like Illumina and Keen Health. Below is a taste of the topics we discussed.It seems timely to start with a discussion about business models for anti-infectives - therapies for illnesses that aren’t typically chronic conditions. There is a gap in the market because

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32:40

Prevention as a Service

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2022/12/07

I’ve been thinking a bit lately about preventative health. We focus a lot in this podcast on therapeutics, some of which I’m personally grateful for. We should keep developing new ones to help people live longer and healthier. But that seems a never-ending game. I don’t see curing all diseases as realistic, nor the only strategy when many diseases can be avoided by changes in behavior. Paying for prevention seems a tricky business. How do you pay for something that doesn’t happen? And who would pay

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26:35

Training AI for Drug Development

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2022/11/23

Designing new compounds to be used as therapeutics is a challenge regardless of the approach. Artificial intelligence shows promise for solving some of those challenges, whether it’s identifying a hit, lead optimization or something else. Ashwini Ghogare is the intrapreneur CEO of Artificial Intelligence and Automation in Drug Discovery at Millipore Sigma. She was kind enough (and patient enough) to educate me on how AI can be used to help with figuring out the synthesis of new compounds and even

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31:30

Competitive Advantage of Information Architecture

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2022/11/09

Your company runs on information to a large degree. But not all of it is accessible to the people who need to make decisions which slows things down, making you less competitive.Seth Earley is the CEO of Earley Information Science. We had a conversation about using artificial intelligence to make information flow faster within companies. The key concept was the use of ontologies in the information architecture. You may be familiar with taxonomies, how we name categories of information. Ontologies

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34:01

Machine Learning in Drug Development

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2022/07/27

One of my goals for this podcast series is to cover the use of AI in everything from drug development to the clinic. This episode sits at the trailhead for that journey. I met Nicolas Tilmans, Founder of Anagenex on Twitter. Anagenex is “building a directed evolution platform to develop new small molecules by combining massively parallel biochemical experiments and machine learning.”Specifically, they are using DNA Encoded Libraries (DELs) to identify small molecules that will bind to targets of

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36:35

Mission, Vision, Values, Systems

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2022/07/20

This week I talked to Don Davis of 5280 Life Sciences Consulting. Don helps companies scale up through leadership development, project and process improvements. He is also the host of the Life Science Success podcast.The challenge comes when a small company of about ten employees becomes successful and gets an influx of cash and all of a sudden is becoming a company of one or two hundred. Interestingly, the first thing he mentioned were mission, vision and values. It’s important to know where you

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26:23

What is a Data Strategy and Why You Need One

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2022/05/11

I met Charles Baldridge, CEO of Sol Analytica on a Zoom call. In an eclectic group of filmmakers, artists, music publishers (and data scientists), Charles mentioned that his company helps others with their data strategy. That set off my curiosity and I invited him to this podcast.I hadn’t really thought about data strategy and didn’t know what it was, but it certainly sounded like something many life science businesses should have.It will be no surprise to anyone that we are awash in data. And we

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35:48

AI from Winter to Spring

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2022/05/04

Machines have been helping us with physical work for a long time. Now with AI, machines are helping with the knowledge work. At the outset, AI was working with numbers. Now it’s working with images, words and language. And I’m discovering it’s everywhere with still great potential ahead.Sidd Bhattacharya, Director of Healthcare Analytics and Artificial Intelligence at PWC gave me a lesson on the history and current state of AI with some thoughts about the future.The reason why you see a huge

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32:09

Failure and Opportunity with AI in Life Science

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2022/04/20

Failure66% of AI projects fail. That’s the bad news. The good news is that in life science we’re not really investing enough or working on the important problems yet. The opportunities are still there. So we’ve got that going for us.Severence McLaughlin is the CEO of DeLorean Artificial Intelligence. He has some thoughts about what is actually AI, how it’s being deployed, and the impact it could make if companies stopped doing science experiments (investing in little test projects here and there)

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49:42

Optical Applications in Life Science

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2022/04/06

Color Science and Digital ImagingI don't think many people paid too much attention to the sort of miracle that produces color technology in a digital device, because we were so used to using color film, which itself is a technological masterpiece to balance the various photo-sensitive pigments that would result in images that we perceive with our human visual system to look the same as the scene we took a picture of. This week’s conversation is with Jeff Carmichael. An expert on imaging systems

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30:47

3D Bioprinting

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2022/03/22

At the beginning of the year, I said I would follow my curiosity. One of the things I was curious about was 3D bioprinting. What does that even mean? I talked to Dr. Mohammad Albanna, CEO and founder of Humabiologics to learn more.Imagine creating 3D structures from living cells and a biological matrix. Then imagine depositing the materials for that structure with an injet printer. I promise, I didn’t get this watching Netflix.Dr. Albanna described for me the story of Dr. Tony Atala who grew a

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35:18

Blockchain Basics

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2022/03/08

Karen Kilroy is the founder of Kilroy Blockchain as well as an O’Reilly Media author.Karen’s company develops blockchain workflows to be implemented for companies. Our podcast conversation meandered far from my notes because, as blockchain is new to me, everything is interesting. We actually started off talking about artificial intelligence and how blockchain has the potential to make AI less scary.For this article, I’ll stick to understanding what it is, presenting some use cases and Karen’s

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43:56

Remote Monitoring and Digital Health

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2022/02/22

If you haven’t already, I imagine many of you are currently or will soon be dealing with aging parents and their desire to stay in their home for as long as possible. And why wouldn’t they? That’s what we would want for ourselves. So how to balance that with knowing when assistance might be necessary? A daily phone call to check in might be annoying for the parent and take the joy out of a genuine conversation for anyone.Alfred Poor is the editor and publisher of HealthTech Insider. We had a

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76 results

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