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PODCAST

The Metabolic Classroom with Dr. Ben Bikman

Welcome to The Metabolic Classroom, a nutritionand lifestyle podcast focused on metabolism, which is how our bodies use energy, and the truth behind why we get sick and fat. Every week, Dr. Ben Bikman shares valuable insights that you can apply in your own life and share with friends and loved ones. The Metabolic Classroom is brought to you by BenBikman.com and InsulinIQ.com. Hosted on Acast. See acast.com/privacy for more information.

health & fitness nutrition

All Episodes

27:57

Why A1C Isn't Enough: Insights from Dr. Ben Bikman...

The Metabolic Classroom with Dr. Ben Bikman ·

2024/08/26

In this episode of The Metabolic Classroom, Dr. Ken Berry and Dr. Ben Bikman discussed the critical role of endogenous insulin, the limitations of focusing solely on glucose levels, and the implications of common markers like A1C and uric acid in understanding metabolic health.Dr. Berry began by highlighting how many primary care physicians misunderstand the function of beta cells in type 2 diabetes, often believing that these cells “burn out” and stop producing insulin. Dr. Bikman clarified that in

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28:45

The Impact of Estrogens on Glucose Metabolism and...

The Metabolic Classroom with Dr. Ben Bikman ·

2024/08/16

In this episode of The Metabolic Classroom, Dr. Ben Bikman explores the metabolic effects of estrogens, particularly their role in glucose metabolism.Estrogens, mainly produced in the gonads, play a crucial role in regulating blood glucose by enhancing insulin sensitivity. Dr. Bikman explained that estrogens improve insulin signaling through pathways such as PI3 kinase and AKT, which are essential for glucose uptake in muscle and fat tissues. Additionally, estrogens activate AMP-activated protein

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32:20

Understanding Anabolic Resistance: Dr. Ben Bikman on...

The Metabolic Classroom with Dr. Ben Bikman ·

2024/08/12

Dr. Ben Bikman, a biomedical scientist and professor of cell biology, discusses the phenomenon of anabolic resistance.Anabolic resistance, primarily a problem associated with aging, refers to the reduced ability of muscles to synthesize protein in response to anabolic stimuli, such as protein intake and resistance exercise. This condition leads to a decline in muscle mass and function over time, contributing to a loss of physical capacity, increased risk of falls, and a greater dependency on others

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26:38

The Metabolic Health Benefits of Fermented Foods with...

The Metabolic Classroom with Dr. Ben Bikman ·

2024/08/08

Dr. Ben Bikman, professor of cell biology and metabolic scientist, delivers a lecture on the importance of fermentation and fermented foods from a metabolic perspective. He began by defining fermentation as the metabolic process where bacteria convert carbohydrates into organic molecules, emphasizing that bacteria primarily consume carbohydrates, not fats or proteins. Fermented foods such as dairy, vegetables, and beverages like kombucha and kefir are common examples. Fermentation not only changes

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36:58

The Randle Cycle: How Your Body Chooses Between...

The Metabolic Classroom with Dr. Ben Bikman ·

2024/07/23

In this episode of The Metabolic Classroom, Dr. Bikman introduces the concept of the Randle Cycle, also known as the glucose fatty acid cycle, in a lecture aimed at providing a better understanding of metabolism. The Randle Cycle, first identified by Dr. Philip Randle and his colleagues in the 1960s, explores how cells decide between using glucose or fatty acids for fuel. Dr. Bikman emphasized that this cycle has been misinterpreted on social media and aims to clarify its relevance in metabolic

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40:14

Leptin and Leptin Resistance Explained

The Metabolic Classroom with Dr. Ben Bikman ·

2024/07/18

Dr. Ben Bikman’s lecture on leptin, delivered in his Metabolic Classroom series, highlights the hormone's critical role in metabolism. Leptin, primarily produced by white fat tissue, helps regulate energy balance by signaling the brain to suppress appetite and promoting mitochondrial biogenesis in muscle cells. Leptin levels correlate with body fat, and various factors like insulin and TNF alpha influence its production. Insulin significantly stimulates leptin secretion, highlighting a complex

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31:58

Sarcopenic Obesity

The Metabolic Classroom with Dr. Ben Bikman ·

2024/06/28

Professor Ben Bikman discusses sarcopenic obesity, a condition involving obesity and muscle loss. This condition results from factors like sedentary lifestyles, aging, and metabolic disturbances. While obesity is common, sarcopenia typically affects the elderly, diseased, or very sedentary individuals. The combination of excessive fat and muscle loss makes sarcopenic obesity particularly challenging.Dr. Bikman explains the crucial role of muscle in blood glucose regulation. Muscle mass reduction

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27:22

Alcohol and Insulin Resistance

The Metabolic Classroom with Dr. Ben Bikman ·

2024/06/20

In this episode of The Metabolic Classroom Dr. Ben Bikman focused on the effects of alcohol on insulin resistance, emphasizing how ethanol, the main form of alcohol, influences the brain and metabolism. He highlighted that alcohol is primarily metabolized by the liver and can cause insulin resistance through both direct and indirect mechanisms. Dr. Bikman detailed the molecular pathways by which ethanol inhibits insulin signaling, notably by disrupting the insulin receptor substrate (IRS1) and

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36:26

Energy Toxicity and Insulin Resistance

The Metabolic Classroom with Dr. Ben Bikman ·

2024/06/06

In this episode of The Metabolic Classroom, Dr. Bikman, a biomedical scientist and professor of cell biology, delves into the concept of energy toxicity.He begins by explaining that energy toxicity attempts to explain why certain cells, particularly those capable of storing energy like muscle and liver cells, become insulin resistant. The primary idea is that when these cells accumulate excess energy, particularly in the form of triglycerides, they become resistant to further energy storage by

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10:43

Sleep and Insulin Resistance

The Metabolic Classroom with Dr. Ben Bikman ·

2024/06/06

In this episode of The Metabolic Classroom, Dr. Bikman begins by emphasizing the critical role of insulin in regulating the body’s use of fuel, and influencing whether nutrients are stored or burned.He highlights that food is a primary driver of insulin levels, but other factors like stress and sleep deprivation significantly impact insulin resistance.Stress, often exacerbated by poor sleep hygiene, leads to elevated levels of cortisol and epinephrine, which in turn increase blood glucose levels

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30:39

Exogenous Ketones with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/05/23

In this episode of The Metabolic Classroom, Dr. Bikman explores the history, science, and benefits of ketones, focusing on exogenous ketones.Ben highlights the significant benefits of ketones for brain health. He disputes the common belief that glucose is the brain’s preferred fuel, citing research by Dr. George Cahill that indicates the brain relies heavily on ketones during fasting.The classroom also addresses the evolution and advantages of exogenous ketones. Early forms of exogenous ketones,

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17:50

Heart Health: Fat Matters

The Metabolic Classroom with Dr. Ben Bikman ·

2024/05/20

In this episode of The Metabolic Classroom, Dr. Ben Bikman challenges the traditional view that saturated fats are the primary cause of atherosclerotic plaques and heart disease. He asserts that while plaques, or atheromas, in coronary arteries are composed partly of fats and foam cells, the exact process of plaque formation remains speculative. Dr. Bikman emphasizes that anyone claiming to know the definitive cause of plaque formation is likely overstating their knowledge. Foam cells, which are

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35:59

Uric Acid with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/05/15

This episode of The Metabolic Classroom is sponsored by RxSugar. Use this link to get 20% off: https://rxsugar.com/discount/BEN2002:10 - Overview of Uric Acid: Explanation of what uric acid is and its origins from purine metabolism.03:16 - Uric Acid and Hyperuricemia: Discussion on uric acid production, excretion, and the condition of hyperuricemia.05:09 - Gout and Uric Acid Crystallization: How high uric acid levels lead to gout and kidney stones.07:08 - Importance of Uric Acid in Metabolism: Why

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29:14

Saturated Fat with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/05/07

In this episode of The Metabolic Classroom, Professor Ben Bikman, an expert in metabolic research, discusses the debate surrounding saturated fat and its impact on insulin resistance.Dr. Bikman addresses misconceptions about saturated fat perpetuated by proponents of plant-based diets, who often blame meat-based saturated fats for insulin resistance. He refers to his own 2011 research, highlighting the role of toll-like receptor four (TLR4) activation in inducing inflammation and insulin resistance,

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31:14

Salt and Cardiometabolic Health with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/05/02

This episode of the Metabolic Classroom is sponsored by Redmond Real Salt. Use code BEN15 to get 15% off of their products: https://redmond.lifeSummary:In this lecture, Professor Ben Bikman explores the cardiometabolic effects of salt intake, detailing its role in electrolyte balance, fluid regulation, nerve function, muscle contractions, acid-base balance, and nutrient absorption. He explains the renin-angiotensin-aldosterone system (RAAS) and its response to low blood pressure or sodium levels,

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42:17

Lipedema with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/04/24

Dr. Ben Bikman, a biomedical scientist and expert in cell biology, welcomes his audience to a discussion on lipedema, a topic he’s been asked about frequently. He highlights the importance of addressing insulin resistance through diet.Ben begins by providing a primer on adipose tissue, explaining its composition and the role of fat cells and fibroblasts. He delves into the structural changes in collagen within fat tissue, particularly in lipedema, where there's an overproduction of collagen leading

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34:37

The Metabolism of Male Infertility

The Metabolic Classroom with Dr. Ben Bikman ·

2024/04/18

Dr. Ben Bikman discusses the intricate relationship between metabolic health and male infertility.While metabolic health is often associated with conditions like obesity and diabetes, Dr. Bikman emphasizes its relevance to less obvious issues like male infertility. He notes that while the processes of reproduction differ between the sexes, they share a common metabolic core.Ben highlights that infertility affects approximately 15% of couples trying to conceive, with men contributing to around 30% of

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37:25

The Metabolism of Female Infertility

The Metabolic Classroom with Dr. Ben Bikman ·

2024/04/11

In this lecture, Professor Ben Bikman delves into the metabolic aspects of female infertility, specifically focusing on the influence of insulin resistance. He begins by highlighting the high prevalence of infertility among women of reproductive age, with up to 15% affected globally, and particularly prevalent in regions with high rates of insulin resistance, such as Sub-Saharan Africa, South Asia, and the Middle East.Insulin resistance, a condition where cells become less responsive to insulin,

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35:47

Fatty Liver Disease with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/04/01

In this Metabolic Classroom episode, Dr. Bikman delves into the intricate dynamics of fatty liver disease, a prevalent metabolic problem affecting millions worldwide. Describing the liver as the “soccer mom” of metabolism due to its involvement in various metabolic processes, Ben emphasizes the liver’s central role in nutrient metabolism, particularly in handling fats.Fatty liver disease, once primarily associated with alcohol consumption, has now become a widespread issue driven by metabolic

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33:58

Strategies for Fat Burning with Dr. Ben Bikman

The Metabolic Classroom with Dr. Ben Bikman ·

2024/03/28

In this lecture from the Metabolic Classroom, Dr. Ben Bikman, a biomedical scientist specializing in metabolism, delves into various strategies for fat loss.He begins by highlighting the importance of understanding fat tissue dynamics, focusing particularly on hormones, drugs, and sex-specific effects. The main topic for the lecture is strategies for fat loss, which Bikman divides into three categories: drugs, surgical interventions, and lifestyle changes.Bikman briefly revisits the topic of drugs

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127 results

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