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PODCAST

The Readout Loud

STAT’s weekly biotech podcast, breaking down the latest news, digging deep into industry goings-on, and giving you a preview of the week to come.

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All Episodes

28:08

From Tradeoffs: Race to the Bottom

The Readout Loud ·

2024/09/28

We’re excited to share the first episode in a new podcast series on generic drugs from Tradeoffs. It’s called ‘Race to the Bottom,’ and each week the show examines the problems undermining the generic drugs we all rely on — and how we could fix them. Take a listen, and we’ll see you next week.

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32:02

324: Genentech's cancer pivot, Pfizer's sickle cell...

The Readout Loud ·

2024/09/26

Our colleague Jonathan Wosen joins us to discuss the recent setbacks and wins in oncology R&D, including Genentech's decision to shut down its cancer immunology group, and the global ambitions of Akeso, the Chinese biotech behind Summit Therapeutics’ recent positive results. We also chat about the latest news in the life sciences, including Pfizer’s sudden announcement to pull its sickle cell drug and the imminent approval of Bristol Myers Squibb’s schizophrenia treatment.

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35:21

323: Cannabinoids for weight loss, a cancelled ad...

The Readout Loud ·

2024/09/19

Mizuho analyst Jared Holz joins us to discuss what the Federal Reserve's long-awaited decision to lower interest rates means for biotech stocks and startups. Elaine, Adam, and Allison also discuss the latest news in life sciences, including the use of cannabinoid receptor drugs in weight loss and the Lasker Awards, a.k.a. "America's Nobel."

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32:57

322: A new threat to Merck's blockbuster cancer...

The Readout Loud ·

2024/09/12

STAT reporter Matt Herper joins us to break down all the angles of this week's tumultuous week in cancer immunotherapy, including his up-close look at Summit co-CEO Bob Duggan. We also discuss the latest news in the life sciences, including Moderna pruning its pipeline and its spending, plus results from a study that tested a GLP-1 drug in children.

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35:18

321: Summit's upcoming cancer results, Recursion's...

The Readout Loud ·

2024/09/05

We discuss the next big trend in obesity drug development — treatments that target the amylin hormone. Companies argue that these types of drugs could lead to less nausea and muscle loss, and the first big readout is coming later this year. We also chat about an upcoming presentation from Summit Therapeutics on its cancer drug that beat Merck’s Keytruda, mixed data from Recursion’s lead AI-derived drug candidate, and more news in the life sciences.

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37:34

320: Jim Wilson's next venture, a surprise startup...

The Readout Loud ·

2024/08/29

STAT biotech reporter Jonathan Wosen joins us to discuss gene therapy pioneer Jim Wilson's exit from his decades-long tenure at the University of Pennsylvania. We also discuss the latest news in the life sciences, including the surprising collapse of a gene editing company, Eli Lilly's pitch to consumers, and more.

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22:42

From "Say More": What Happens When AI Decides Your...

The Readout Loud ·

2024/08/23

This week, STAT's Casey Ross and Bob Herman joined the Boston Globe's "Say More" podcast to talk about their reporting on AI and Healthcare. We're sharing that episode here with you now. Enjoy!

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34:07

319: BioMarin's executive shakeup, a GLP-1 lowers...

The Readout Loud ·

2024/08/22

It's a guest-free episode this week, giving Allison, Adam and Elaine ample time to chat about the management shakeup at BioMarin, including the announcement that James Sabry, the former Roche dealmaker, was joining the company as its new chief business officer. We can't seem to go a week without talking about GLP-1 medicines, so in true form, Elaine walks us through new study findings that showed Lilly's Zepbound greatly reduced the risk of diabetes. We also discuss a separate study that potentially

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21:16

318: Drug pricing drops & psychedelics under fire

The Readout Loud ·

2024/08/15

STAT’s chief Washington correspondent Rachel Cohrs Zhang joins us to discuss the discounts and how this first round of negotiations between pharmaceutical companies and Medicare officials played out. After that, we chat with our colleague Meghana Keshavan about the latest news in the psychedelics world, including the retraction of three research papers.

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28:52

317: VC struggles, drug pricing negotiations, &...

The Readout Loud ·

2024/08/08

STAT's Washington Correspondent John Wilkerson joins us to discuss the first round of drug pricing negotiations under the Inflation Reduction Act, which will wrap up by September 1. We also cover the latest news in the life sciences including the merger of AI drug development companies Recursion Pharmaceuticals and Exscientia, Novo Nordisk's decision to pause its regulatory submission for Wegovy's use in patients with heart failure with preserved ejection fraction, and the state of biotech VC.

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34:15

316: The long journey to make malaria vaccines, and...

The Readout Loud ·

2024/08/01

Andrew Joseph, STAT's Europe correspondent, joins us to talk about his special report on the 40-year quest to develop the world's first malaria vaccines. We also cover the latest news in the biotech industry, including Sarepta Therapeutics' move to censor a patient video, data from a new Duchenne gene therapy, and a campaign by Mount Sinai to stifle debate about its controversial brain research following revelations made by a STAT investigation.

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32:46

315: UnitedHealth's doctor empire, an FDA departure,...

The Readout Loud ·

2024/07/25

What makes UnitedHealth similar to Standard Oil? Is Viking Therapeutics an attractive acquisition target? And is Adam good at math?We discuss all that and more in this week’s episode of “The Readout LOUD,” STAT’s biotech podcast. Tara Bannow, our hospitals and insurance reporter, joins us to talk about a new investigation that shows how UnitedHealth wields its unrivaled physician empire to boost its profits and expand its influence. We also cover the latest news in the life sciences, including

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33:02

314: JD Vance's biotech ties, Cassava resignations,...

The Readout Loud ·

2024/07/18

Our Washington correspondent Sarah Owermohle joins us to talk about how JD Vance, Donald Trump's newly announced running mate, could influence health policy if Trump wins the election. We also discuss the latest news in the biopharma industry, including the latest developments in the ongoing controversy surrounding Cassava’s Alzheimer’s drug, shortages of insulin as Novo Nordisk and Eli Lilly turn their focus toward GLP-1 drugs, and a shakeup in leadership at Gilead.

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34:52

313: Biotech layoffs, founder-focused VC, & a big...

The Readout Loud ·

2024/07/11

STAT's West Coast biotech reporter Jonathan Wosen joins "The Readout LOUD" to discuss what’s driving workforce cuts. Plus, entrepreneurs Alexis Borisy and Zach Weinberg call in to discuss their biotech incubator Curie.Bio and how they hope to “free the founders.” We also discuss a big change in Pfizer’s leadership and the debate over a new side effect tied to the diabetes drug Ozempic.

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28:33

312: Medicare coverage for GLP-1 drugs, AI, and...

The Readout Loud ·

2024/06/27

STAT health tech reporter Brittany Trang guest co-hosts "The Readout LOUD" this week, where we discuss AI for drug development, the latest in the H5N1 bird flu outbreak, a surprise entrant to the GLP-1 field, and more news in the life sciences. And STAT chief Washington correspondent Rachel Cohrs Zhang joins the podcast to talk about a new proposal for obesity drug coverage in Washington and what to expect from the first presidential debate.

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34:10

311: Fauci's memoir, Alnylam's tenuous trial, and a...

The Readout Loud ·

2024/06/20

STAT reporter Jason Mast joins us to discuss Anthony Fauci's memoir "On Call," which was published this week. Hosts Allison DeAngelis and Adam Feuerstein also dissect Alnylam's forthcoming clinical trial data and take stock of how the biotech markets are succeeding and potentially falling flat midway through the year.For more on Fauci's memoir "On Call," go here; for Adam's primer on Alnylam's ATTR-CM trial, go here; read about BridgeBio's plans here; and for more on biotech startup financing, go

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38:46

310: Duchenne gene therapy setback, Alzheimer's drug...

The Readout Loud ·

2024/06/13

STAT's Nicholas Florko joins to explain what it means to be a reporter writing about the commercial determinants of health. Hint: Florko's most recent stories focus on weed, vapes, and raw milk. And instead of being chained to a desk, he often drives around to convenience stores and buy bad stuff — all in the name of good journalism. But first, co-hosts Adam Feuerstein and Allison DeAngelis chat about Pfizer's Duchenne gene therapy setback, the likely approval of a new treatment for Alzheimer's

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29:34

309: Psychedelics at the FDA, ASCO recap, & MorphoSys...

The Readout Loud ·

2024/06/06

STAT colleague Meghana Keshavan joins us to dissect Lykos Therapeutics' meeting with an FDA advisory committee. We also discuss the latest news in the health and life sciences, including stories from major biotech conferences.To learn more about Lykos' advisory committee meeting, go here; for more on the tumult at BIO, go here; for a recap of ASCO, go here; to read the latest on Novartis' acquisition of MorphoSys, go here. And you can sign up for Adam’s new newsletter, Biotech Scorecard, here.

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28:41

308: An ASCO preview & another Duchenne trial failure

The Readout Loud ·

2024/05/30

We preview some of the research that will be presented at The American Society of Clinical Oncology conference in Chicago. We also discuss the latest news in the health and life sciences, including a milestone in lung disease R&D and a Duchenne muscular dystrophy confirmatory trial failure. To read more about Merus' combination therapy, go here; For more on Johnson & Johnson's mixed data, click here; For more on Nippon Shinyaku's Duchenne drug trial failure, go here; To read more on Insmed's

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31:12

307: More tumult at BIO & coercive care for sickle...

The Readout Loud ·

2024/05/23

This week on “The Readout LOUD,” STAT's Chief Washington Correspondent Rachel Cohrs Zhang joins us to discuss the layoffs at trade group BIO and how things may be changing at the trade group. We also invite STAT reporter Eric Boodman on to talk about his new investigative series of stories exploring how Black women with sickle cell disease were coerced into getting sterilized.

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388 results

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