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PODCAST

The a16z Show

Andreessen Horowitz

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

technology entrepreneurship

All Episodes

00:43:04

Fei-Fei Li on Spatial Intelligence and Robotics

The a16z Show ·

2026/07/28

Last week, World Labs announced its acquisition of SceniX, bringing together two teams working on one of AI's biggest unsolved problems: how to give machines a true understanding of the physical world.Martin Casado sits down with Fei-Fei Li, co-founder and CEO of World Labs, creator of ImageNet, and pioneer of spatial intelligence, alongside Yunzhu Li, co-founder of SceniX and assistant professor at Columbia University. They discuss why World Labs acquired SceniX, how simulation can unlock the next

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00:29:16

Steven Sinofsky: AI Doesn't Need New Rules Yet

The a16z Show ·

2026/07/27

Steven Sinofsky joins Theo Jaffee and Sofia Puccini for a conversation on AI regulation, open-source models, and what history can teach us about technological revolutions. Drawing on decades of experience leading products at Microsoft, Sinofsky argues that governments are rushing to regulate AI before they fully understand the technology, risking innovation in the process. They discuss the "precautionary principle," why open source has historically accelerated innovation, the role of regulation in

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00:32:35

Ben Horowitz: The Fight Over Open Source AI

The a16z Show ·

2026/07/26

Ben Horowitz joins Theo Jaffee and Sofia Puccini to discuss one of the biggest debates in AI today: the future of open-source models. They examine the growing push to restrict open models, why Ben believes open source is critical for security, innovation, and competition, and what happens if a handful of frontier labs come to dominate the AI ecosystem.They also discuss distillation, AI monopolies, China's role in open-source AI, robotics, manufacturing, the economics of frontier models, and why Ben

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00:23:04

Sriram Krishnan on Open Source AI's Biggest Week Yet

The a16z Show ·

2026/07/24

Sriram Krishnan joins Theo Jaffee and Sofia Puccini just after concluding his tenure as Senior White House Policy Advisor on AI to discuss one of the biggest weeks yet for open-source AI. They unpack the rapid release of models including Kimi K3 and Qwen, why open models are putting pressure on frontier labs, and what it means for pricing, competition, and the future of AI infrastructure. They also discuss AI policy, distillation, cybersecurity, the role of open-weight models, whether the U.S

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00:45:25

Building the Physical AI Stack | Travis Kalanick on TBPN

The a16z Show ·

2026/07/23

Travis Kalanick joins TBPN to discuss Atoms, his vision for industrial AI, and why he believes the biggest opportunities in AI lie beyond software. He explains how Atoms is bringing autonomy to mining, logistics, and food production, why robotics will reshape physical industries, and how lower costs and greater automation could unlock entirely new economic opportunities. Travis also reflects on raising $1.7 billion, building in stealth, regulation, hiring, and what he's learned since

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01:32:13

Travis Kalanick Is Back | Building the Future of...

The a16z Show ·

2026/07/22

Travis Kalanick, Ben Horowitz, and Erik Torenberg reunite to reflect on Uber's early days, the investment that almost happened, and why Kalanick believes the next great technology opportunity lies beyond software. They discuss the lessons of building Uber, the value of founder-led companies, and why Kalanick spent nearly eight years quietly building Atoms before stepping back into the spotlight. The conversation explores industrial AI, robotics, autonomy, mining, food production, and Kalanick's

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01:20:33

Why Physical AI Is the Next Frontier | Applied Intuition

The a16z Show ·

2026/07/21

Applied Intuition has spent the past decade building the software that powers intelligent machines, from passenger vehicles and trucks to defense systems, mining equipment, and industrial robots. In this conversation, Marc Andreessen and Erik Torenberg sit down with Applied Intuition cofounders Qasar Younis and Peter Ludwig to discuss the emergence of physical AI and the company's latest launch, Dana, a new platform designed to accelerate the development of autonomous systems. They explore

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00:28:08

Hugging Face's CEO on Open Source AI, Model Routing,...

The a16z Show ·

2026/07/20

As governments weigh new restrictions on frontier AI models, one question is becoming increasingly important: what role should open source play in the future of artificial intelligence? Theo Jaffee and Sofia Puccini speak with Hugging Face CEO Clément Delangue about AI regulation, open source safety, model routing, and why he believes competition—not consolidation—is essential for the industry's future. They discuss GPT-5, government oversight of frontier models, Hugging Face surpassing $100 million

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00:25:47

Amjad Masad on Going Direct, Building Replit, and the...

The a16z Show ·

2026/07/17

Recorded live at the New Media Summit, Erik Torenberg sits down with Replit founder and CEO Amjad Masad to discuss founder-led storytelling, building in public, and the role of media in company building. Masad reflects on Replit’s decade-long journey, including the years before the company’s recent breakout growth, and explains why communicating a vision can be just as important as executing on it. He argues that for many founders, especially those building ambitious products ahead of the market,

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01:17:11

Replay 2025: David Sacks on AI, Crypto, and America's...

The a16z Show ·

2026/07/16

As part of our summer replay series, we're revisiting one of our most-discussed conversations from the past year. David Sacks joins Marc Andreessen, Ben Horowitz, and Erik Torenberg to discuss the intersection of AI, crypto, regulation, and American competitiveness. The conversation explores the Trump administration's approach to AI and crypto policy, open source AI, export controls, energy and infrastructure, the global race with China, and the role regulation plays in shaping innovation. They also

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01:05:18

From the Archive: Can Anyone Catch NVIDIA? | The...

The a16z Show ·

2026/07/15

As part of our summer replay series, we're revisiting one of our favorite conversations on the future of AI infrastructure. SemiAnalysis founder Dylan Patel joins Erin Price-Wright, Guido Appenzeller, and Erik Torenberg to examine the rapidly evolving economics of AI hardware, from GPUs and custom silicon to data centers, power, and the global race for compute. The conversation explores NVIDIA's competitive advantages, the rise of custom chips from Google, Amazon, and Meta, the economics of frontier

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00:31:49

Is AI a Bubble? | Gavin Baker on Data Centers, GPUs,...

The a16z Show ·

2026/07/14

As part of our summer replay series, we're revisiting one of the standout conversations from Runtime, a16z's conference on AI infrastructure and the future of computing. Gavin Baker, Managing Partner and CIO of Atreides Management, joins David George to examine the biggest questions surrounding today's AI investment cycle. Is AI a bubble? What does the unprecedented buildout of data centers, GPUs, and compute infrastructure mean for the economy? And how should investors think about the companies

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00:37:20

Before Blockchains, There Was State Machine Replication

The a16z Show ·

2026/07/13

Every blockchain today relies on replication techniques first developed in the 1980s by researchers who weren't thinking about cryptocurrencies at all. In this episode, Tim Roughgarden speaks with MIT professor and Turing Award winner Barbara Liskov, one of the pioneers of programming languages, fault tolerance, and distributed systems. Joined by a16z crypto research partner Ittai Abraham, they trace the evolution of ideas that now underpin modern blockchain networks. The conversation explores

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00:21:35

How Bitcoin Rewired a Classic Computer Science Problem

The a16z Show ·

2026/07/10

We're excited to share a special feed drop from The a16z Crypto Show. In the first episode of First Principles: The Scientific Roots of Blockchain Technology, Tim Roughgarden and Ittai Abraham trace the decades of computer science research that laid the foundation for modern blockchains. Long before Bitcoin, researchers were studying one of distributed computing's hardest challenges: how independent machines can reliably agree on a shared state, even when some participants are faulty or malicious

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00:45:14

Mark Zuckerberg & Priscilla Chan: How AI Will Help...

The a16z Show ·

2026/07/09

As part of our summer replay series, we're revisiting one of our favorite conversations from the past year. Mark Zuckerberg and Dr. Priscilla Chan join Ben Horowitz, Vineeta Agarwala, and Erik Torenberg to discuss the Chan Zuckerberg Initiative's ambitious effort to help cure, prevent, and manage disease by the end of the century. Rather than funding individual breakthroughs, CZI is focused on building the tools and infrastructure that can accelerate scientific discovery across entire fields. The

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01:30:06

Adam Neumann: This Is How You Build Iconic Companies

The a16z Show ·

2026/07/08

Adam Neumann joins Marc Andreessen, Ben Horowitz, and Erik Torenberg for a candid conversation about entrepreneurship, failure, and building Flow. Neumann reflects on his childhood, military service, immigration to the United States, the rise and fall of WeWork, and what he learned from one of the most scrutinized founder journeys in technology. He explains why Flow is focused on rethinking housing, community, and belonging, and why he believes technology can fundamentally improve how people

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01:01:24

Is Software Losing Its Head?

The a16z Show ·

2026/07/07

Seema Amble, Steven Sinofsky, and Elena Burger unpack one of the biggest questions facing enterprise software: what happens when AI agents become the primary users of software instead of humans? The conversation explores the rise of "headless" software, why APIs and agentic workflows are reshaping enterprise applications, and whether traditional SaaS products are becoming systems of record rather than systems of engagement. They discuss Salesforce's Headless 360 announcement, MCP, enterprise

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00:42:51

a16z Goes Global: Why American Tech Must Lead the World

The a16z Show ·

2026/07/03

Ben Horowitz is joined by Anne Neuberger, Raghu Raghuram, and Jen Kha to discuss a16z's expanding international strategy and the growing role technology plays in economic growth, national security, and global partnerships. The conversation explores why America's technology leadership matters beyond Silicon Valley, how AI is reshaping relationships between governments and the private sector, and why countries around the world are looking to adopt frontier technologies while building stronger

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00:41:15

Outsmarting Uber: Why Bolt Wins in Europe

The a16z Show ·

2026/07/02

What does it take to build a global mobility company from a country of just 1.3 million people? Markus Villig, founder and CEO of Bolt, joins the show to share how he scaled from Estonia to 50+ countries, navigating early scrappy days, a near-bankruptcy from expanding too fast, and the hard-won lessons behind Bolt’s capital-efficient growth. They also discuss building in Europe vs. the U.S., competing against much better-funded rivals, and why culture and ambition matter more than

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01:15:58

Rick Rubin on AI, Creativity, and The Way of Code

The a16z Show ·

2026/07/01

Rick Rubin joins Marc Andreessen, Ben Horowitz, Anjney Midha, and Erik Torenberg to discuss creativity, artificial intelligence, and his book The Way of Code, which reimagines the Tao Te Ching for the age of AI. The conversation explores vibe coding, remix culture, artistic process, entrepreneurship, and what AI changes, and doesn't change, about creativity. Rubin argues that AI is best understood not as a replacement for artists, but as another creative tool, one that expands what's possible while

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1,198 results

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