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PODCAST

Longevity Roadmap

Dr. Buck Joffrey sits down with leading scientists in the field of longevity to explore cutting-edge research, emerging therapies, and what it really takes to live longer—healthier.

health & fitness alternative health

All Episodes

44:55

107: Longevity Supplements - The Novos Approach

Longevity Roadmap ·

2024/10/28

Dr. Diogo Barardo, Director of Research and Development at Novos, joins Buck to discuss Novos’ innovative approach to longevity supplements, unpacking the differences between biological and epigenetic aging and the impact of the Drug Age database. He details how Novos evaluates compounds for safety and efficacy, the unique ingredients in their flagship NovoScore, and the promising roles of lithium microdoses and NAD precursors. Their conversation also delves into the latest in longevity

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40:23

106: Nitric Oxide - The X Factor in Longevity?

Longevity Roadmap ·

2024/10/21

Buck and Dr. Nathan Bryan delve into the pivotal role of nitric oxide in human physiology, with a particular focus on cardiovascular health and aging. Dr. Bryan breaks down the body’s nitric oxide production processes, how everyday lifestyle choices impact its levels, and what happens when there’s a deficiency. He also explores the surprising connection between oral hygiene and nitric oxide, the risks associated with proton pump inhibitors, and the promise of emerging products designed to boost

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38:14

105: Understanding Heart Rate Variability

Longevity Roadmap ·

2024/10/14

Buck speaks to Dr. Torkil Færø, a Norwegian general practitioner, emergency physician, and seasoned traveler with Doctors Without Borders, to discuss the crucial relationship between stress, heart rate variability (HRV), and overall health. Dr. Færø delves into how HRV serves as a key indicator of our body’s autonomic nervous system balance, showing how lifestyle factors, particularly chronic stress, can undermine well-being. He highlights practical strategies, from breathwork to dietary

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18:49

104: The Real Science Behind Mitochondrial Health

Longevity Roadmap ·

2024/10/07

Buck discusses the implications of mitochondrial dysfunction on aging, and the unique genetics of mitochondrial DNA. He also explores innovative approaches to enhance mitochondrial health, including gene therapy and the use of specific pharmaceuticals and supplements. Buck emphasizes the importance of understanding mitochondrial function in the context of health and longevity, while also addressing the potential challenges posed by medications like statins and conditions such as long COVID. 02:07

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20:54

103: Microplastics and Your Health - One More Thing...

Longevity Roadmap ·

2024/09/30

Buck delves into the pervasive issue of microplastics, exploring their sources, health risks, and potential strategies for detoxification and exposure reduction. He discusses how microplastics infiltrate our food, water, and air, and the alarming health implications they pose, including chronic inflammation and potential links to cancer, as well as practical steps to minimize exposure to microplastics in daily life.

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01:12:39

102: Everything You’ve Been Told About Fat Loss is a...

Longevity Roadmap ·

2024/09/23

In this episode of Longevity Junky, Buck and Nikki tackle one of the most contentious and polarizing areas of longevity, diet with Bio Layne founder Dr. Layne Norton. Learn more about BioLayne and Dr. Layne Norton: https://biolayne.com/coach/layne-norton/ Full episode in video available on YouTube: https://www.youtube.com/channel/UCh6LlBjtOy7lldU7Ldjw0cw Questions? Send us a message at: www.longevityjunky.com Follow us on social media: Instagram: https://www.instagram.com/longevityjunkypodcast

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01:07:04

101: Can we see mental illness on brain scans?

Longevity Roadmap ·

2024/09/16

Buck introduces his brand new podcast, Longevity Junky. In this episode of Longevity Junky, Buck and co-host Nikki Leigh sit down with renowned psychiatrist and brain disorder specialist, Dr. Daniel Amen, founder of Amen Clinics, to discuss groundbreaking brain imaging techniques like SPECT scans. Dr. Amen shares insights on diagnosing mental health issues through brain mapping and the role of brain health in overall longevity.

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24:44

100: What is Flow?

Longevity Roadmap ·

2024/09/09

Dr. Susan Jackson discusses the concept of flow and its impact on quality of life and performance. Flow is an optimal psychological state where individuals are fully focused on a task and experience a loss of self-consciousness. It enhances the quality of our experience and can positively shape the quality of our lives. Flow can be experienced in various domains, including sports, creativity, and everyday activities. Mindfulness meditation can help access flow by improving focus and attention. The

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17:12

99: What is a Retinal Detachment? A First Person...

Longevity Roadmap ·

2024/09/02

Buck shares his recent experience with a retinal tear and detachment, emphasizing the importance of early diagnosis and treatment to prevent permanent vision loss. He explains the anatomy of the eye, the process of vitreous detachment, and the symptoms of retinal tear and detachment. Buck also discusses the risk factors for these conditions, including high myopia and previous eye surgery. He describes his surgical experience and the use of a gas bubble to reattach the retina.

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23:29

98: Big Tech’s Vision of an Aging Population

Longevity Roadmap ·

2024/08/26

Buck discusses the role of big Tech and the elderly with Keren Etkin, founder of TheGerontechnologist.com. Discussion includes the role of robots, implications for social interaction, as well as the additional opportunities for founders to take advantage of the coming geriatric storm. 01:04 Current Tech for Aging 05:17 Tech for Social-Emotional Support 09:03 The Driving Force Behind the Development 12:00 The Impact of Increasing Longevity 13:54 Affordability of Aging Tech 17:08

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21:42

97: Buck’s Boston Heart Cholesterol Balance Test

Longevity Roadmap ·

2024/08/19

Link to Buck's Results: https://drive.google.com/file/d/19BJaZNYwBxlPx4nR9695Q2NC3nNpgW6y/view?usp=sharing https://drive.google.com/file/d/1br1ikAJKmgKev9X3jkS7nUPdXpAqMzYd/view?usp=sharing Section 1: Overview of Cholesterol Metabolism Cholesterol in the Body: Cholesterol is essential for cell membrane integrity, hormone synthesis, and bile acid production. It is produced endogenously in the liver and absorbed exogenously from dietary sources. Endogenous Production: Cholesterol is

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19:38

96: Cardiovascular Risk Management: Calcium Scores,...

Longevity Roadmap ·

2024/08/12

Buck shares his experience visiting a cardiologist and discusses his family history of heart disease. He explains the importance of coronary calcium CT scans and the significance of calcium scores. Buck also highlights the role of lipoprotein little a (Lp(a)) in cardiovascular disease and the potential for new medications to target and lower Lp(a) levels. He explores the use of low-dose colchicine as an anti-inflammatory treatment for coronary artery disease and atrial fibrillation. 01:23

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18:43

95: What is Atherosclerosis and How to Prevent it

Longevity Roadmap ·

2024/08/05

This week's episode is about atherosclerosis, a condition that leads to cardiovascular disease. Buck explains the role of cholesterol and lipoproteins in the development of atherosclerosis. He emphasizes the importance of understanding this topic as cardiovascular disease is the leading cause of death. The conversation covers the different types of lipoproteins, such as HDL and LDL, and their association with atherosclerosis. Buck also discusses the significance of apolipoprotein B (APO-B) in

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27:46

94: Intermittent vs Prolonged Fasting

Longevity Roadmap ·

2024/07/29

Buck explains the difference between intermittent fasting and prolonged fasting, highlighting the benefits and potential pitfalls of each.

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20:11

93: Alzheimer’s Disease vs Age-Related Cognitive Decline

Longevity Roadmap ·

2024/07/22

Buck interviews Dr. Ken Frumkin on his own journey of aging and cognitive decline.

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26:31

92: Gene Editing 101

Longevity Roadmap ·

2024/07/15

In this episode, Buck discusses gene editing and its potential implications for human health and longevity. He explains the basics of gene editing, including the structure of DNA and how genes are transcribed into proteins, then dives into the history and development of gene editing techniques, focusing on the game-changing CRISPR-Cas9 technology. He also explores the practical applications of gene editing, such as its use in treating sickle cell anemia and other genetic diseases, as well as the

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29:40

91: Ask the Doctor 07/08

Longevity Roadmap ·

2024/07/08

Topics include: 00:25 Protein Intake for Longevity 12:40 Tips to Improve Sleep Quality 22:52 Is Robert F. Kennedy Jr. Controlled by a Worm

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33:24

90: Ask the Doctor 07/01

Longevity Roadmap ·

2024/07/01

Topics include: 00:40 Is Weightloss Simply Calories In and Out? 07:10 Stem Cell Injections for NBA Players? 14:60 Statins for Lowering Cholesterol 23:19 The Impact of Nature and Nurture on Longevity

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28:38

89: The Nine Pillars of Resilience with Stephen...

Longevity Roadmap ·

2024/06/24

Buck Joffrey, MD discusses the concept of resilience with Stephen Sideroff, PhD. Topics include bouncing forward from stress and practical techniques to restore balance, nurture growth, and slow down the aging process. 01:35 Defining Resilience and the Ability to Adapt 08:21 Physical Balance and Mastery: Restoring Balance in the Nervous System 15:26 Self-Relationship: How It Changes Your Physiology 21:47 Resilience and Longevity 23:16 Emotion Balance and Mastery

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54:41

88: Stem Cells - Myth vs Reality with Hans Keirstead,...

Longevity Roadmap ·

2024/06/17

I've been hearing about stem cells for decades. When I was a medical student going into neurosurgery, I seriously considered focusing my research on neuroregeneration with stem cells. As it turns out, few advancements were made in that arena for many years until Hans Keirstead and his team did some groundbreaking work on quadriplegics. Now Hans is focused on longevity. Hans may have found a new type of treatment for what I call inflammaging. His company, Immunis, isolates various proteins and

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166 results

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