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PODCAST

BioTech Nation ... with Dr. Moira Gunn

Welcome to BIOTECH NATION !!! With understandable interviews requiring no background in science, BTN attracts a wide global audience. From everyday people looking for hope in treatments in development, to bioentrepreneurs interested in the experience of their fellow travelers, to venture capitalists looking for possibilities in cutting-edge breakthroughs, to scientists simply interested in the work of others, BioTech Nation is the voice of human endeavor, driving science to new realities for

science life sciences

All Episodes

25:39

A Vaccine for Breast Cancer??? Dr. Amit Kumar,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/08/08

This week on BioTech Nation, Dr. Amit Kumar, President and CEO of Anixa Biosciences, talks about their work on a breast cancer vaccine which targets a protein thought only to be expressed during breastfeeding. Building on research by the Cleveland Clinic, Dr. Kumar describes ongoing human clinical trials and their potential for women with BRCA mutations.

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16:50

Are Your Genes Failing You??? Dr. Noah Davidsohn,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/31

This week on Biotech Nation, Dr. Noah Davidsohn, Co-Founder and Chief Scientific Officer of Rejuvenate Bio. The discussion centers around the regulation of protein expression and its implications for aging and health. Dr. Davidsohn explains how aging disrupts the balance of protein production, leading to various diseases. Rejuvenate Bio's gene therapies aim to restore this balance by targeting specific genes.

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25:33

Living Longer??? Dr. Peter Diamandis, XPrize Founder...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/24

This week of BioTech Nation, Dr. Peter Diamandis about his new book, "Longevity: Your Practical Playbook on Sleep, Diet, Exercise, Mindset, Medications, and Not Dying from Something Stupid". We explore his lifelong interest in extending human health span and discuss practical steps for a healthier, longer life, including sleep, diet, exercise, and mindset. Dr. Diamandis introduces the "longevity escape velocity" concept and the HealthSpan XPRIZE, which aims to reverse aging's functional

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17:48

Psychedelics... Prodrugs... What else? Dr. Sam Clark,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/17

This week on BioTech Nation, Dr. Sam Clark, CEO of Terran Biosciences, discusses prodrugs—modified drugs that improve absorption and efficacy. Also, Terran Biosciences is developing non-hallucinogenic psychedelics by blocking the serotonin 2A receptor and manufacturing psychedelics like LSD and psilocybin for research. Dr. Clark highlights Terran's innovative, tech-inspired approach to rapidly develop affordable medications.

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19:52

A Dual Approach to Combatting Hepatitis... Dr....

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/10

This week on Biotech Nation, Dr. Marianne De Backer, CEO of Vir Biotechnology talks about their Phase 2 clinical trials targeting hepatitis B and D co-infections. Vir's approach uses two drugs: tobevibart (an antibody) and elebsiran (an siRNA). These drugs prevent the virus from entering liver cells and stop it from replicating. Preliminary results are promising, showing a significant reduction in viral RNA and normalization of liver enzyme levels. Dr. De Backer also highlights Vir's

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23:18

Solving Genetic Diseases??? Dr. Neil Kumar, Founder &...

BioTech Nation ... with Dr. Moira Gunn ·

2024/07/03

This week on Biotech Nation, Dr. Neil Kumar, founder and CEO of BridgeBio Pharma. Dr. Kumar emphasizes that genetic diseases, particularly Mendelian diseases caused by single gene mutations, are solvable due to advancements in genetic measurement and understanding. He discusses BridgeBio Pharma's innovative corporate structure, which consists of multiple specialized companies under a centralized infrastructure to efficiently tackle various genetic diseases. This model allows for focused

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25:16

The Next Ozempic or Wegovy... But Without the...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/26

What’s next after Ozempic and Wegovy and the like? How about a drug in development which releases all the relevant hormones, and not just GLP-1. And doesn’t require injecting. Dr. Steffen-Sebastian Bolz from Aphaia (ah-phi-ah) Pharma explains their approach, currently in Phase 2.

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28:59

Everybody Has a Thyroid... What Could Go Wrong??? Dr....

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/19

This week we have a best of rerun with Dr. Mark Sumeray from Amolyt Pharma. Dr. Sumeray talks about their innovative approach to treating hormonal conditions. We’ll talk about two – when your parathyroid has been injured or removed, often during thyroid surgery, and another – when the pituitary starts overproducing growth hormone.

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13:38

Wearable Wonders! Dr. Daniel Kraft, Tech Nation...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/12

This week Dr. Daniel Kraft, Tech Nation Health Chief Correspondent, discusses advanced health tech. Dr. Kraft highlights his use of wearables like the Apple Watch, Oura ring, and non-invasive blood pressure monitors. He also introduces "otherables," which track health without being worn, using devices like cameras and modified WiFi. These technologies enable continuous health monitoring and personalized care.

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32:39

FDA Approval! A New Model for BioPharma... Dr. Sam...

BioTech Nation ... with Dr. Moira Gunn ·

2024/06/04

This week on BioTech Nation, Dr. Sam Blackman, Founder and Head of Research and Development from Day One Biopharmaceuticals, shares the story behind the FDA approval of a groundbreaking drug for the most common childhood brain cancer. Driven by the urgent need for pediatric oncology treatments, Day One's innovative approach led to the development of tovorafenib, targeting BRAF-altered pediatric low-grade gliomas. Through the FireFLY trial, they demonstrated significant efficacy, with 52% of

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13:56

Robo-Docs & VR Surgery??? Dr. Daniel Kraft, Tech...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/29

This week on BioTech Nation, Dr. Moira Gunn and Dr. Daniel Kraft discuss how robotics, AI, and virtual reality are transforming surgery. These technologies make procedures less invasive and improve training and outcomes worldwide. Future advancements may include tiny robots performing internal procedures. Security is crucial to prevent hacking of medical devices.

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16:10

No More Transfusions!!! Dr. John Scarlett, President...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/22

Dr. John Scarlett, President and CEO of Geron Corporation talks about their drug Imetelstat for myelodysplastic syndrome (MDS). MDS patients often require frequent blood transfusions, impacting their quality of life. Imetelstat, a telomerase inhibitor, aims to reduce transfusion dependence by targeting cancer cells in the bone marrow. Phase three trials showed promising results, with 40% of patients experiencing at least an 8-week transfusion-free interval.

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10:26

Closing the Innovation Gap!!! Dr. Daniel Kraft, Tech...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/15

Dr. Daniel Kraft, Tech Nation Health Chief Correspondent discusses the gap between medical innovation and its adoption into standard practice. He highlights that it typically takes 17 years for a medical discovery to become common practice, but big data and AI could accelerate this. He emphasizes the importance of sharing medical data and initiatives like Stuff That Works Health and EveryCure.

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21:21

The Virtual Cell??? Dr. Steve Quake, Head of Science...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/08

This week, Dr. Steve Quake from the Chan Zuckerberg Initiative about their goal to tackle all human diseases in the next century. We discuss CZI's innovative approach, including building Biohubs and funding collaborative research. Dr. Quake explains the importance of something called The Virtual Cell project, aiming to use AI to model every human cell. We also address ethical concerns about AI in bioweapons research and the need for regulatory measures.

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16:48

How Can Sound Deliver Drugs??? Dr. Neal Kassell,...

BioTech Nation ... with Dr. Moira Gunn ·

2024/05/01

This week on Biotech Nation, I speak with Dr. Neal Kassell about focused ultrasound technology. We discuss its noninvasive approach, its diverse applications in treating various medical conditions, and its potential to revolutionize treatments for diseases like Alzheimer's, Parkinson's, and cancer. Dr. Kassell also shares insights into ongoing clinical trials and the rapid growth of focused ultrasound as a global standard of care.

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23:02

70% of Breast Cancers and a Link to Prostate...

BioTech Nation ... with Dr. Moira Gunn ·

2024/04/24

This week on BioTech Nation, we explore new efforts in treating cancer with Dr. Sean Bohen, President and CEO of Olema Oncology. We discuss progress in treating breast cancer, particularly ER+/HER2- breast cancer, which accounts for 70% of diagnoses this year. They examine the biology behind these cancers and how Olema's lead compound, palazestrant, works to antagonize the estrogen receptor, halting cancer cell growth. They also touch on the ongoing Phase 3 trial, OPERA-01, and the

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19:54

Tiny RNAs, Big Cures!!! Dr. Sanjay Shukla, President...

BioTech Nation ... with Dr. Moira Gunn ·

2024/04/17

This week - Dr. Sanjay Shukla, CEO of Atyr Pharma, discusses the revolutionary potential of mRNA technology in creating new medicines. They explore Atyr's pioneering approach to leveraging tRNA fragments for treating pulmonary sarcoidosis and other organ-specific conditions, aiming to improve patient outcomes while minimizing reliance on conventional therapies like steroids.

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23:33

How Can a Treatment Become a Vaccine??? Dr. Peter...

BioTech Nation ... with Dr. Moira Gunn ·

2024/04/10

Dr. Peter DeMuth, Chief Scientific Officer of Elicio Therapeutics, discusses the revolutionary approach of detecting cancer at its earliest stages through circulating tumor DNA (ctDNA) tests. Highlighting their innovative treatment method, which aims to train the body's immune cells to recognize and destroy cancer cells, the episode explores the potential transition from treatment to vaccine, offering hope for more effective and durable solutions.

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17:08

Cancer Vaccines??? Dr. Chris Pirie, Co-Founder & COO...

BioTech Nation ... with Dr. Moira Gunn ·

2024/04/03

In this week's episode, Dr. Moira Gunn interviews Dr. Chris Pirie from HDT Bio about their novel approach to cancer prevention through vaccines. They discuss leveraging mRNA technology to target specific tumor mutations and prime the immune system to recognize and eliminate cancer cells. Dr. Pirie highlights ongoing efforts to develop vaccines for prostate, pancreatic, and breast cancers, emphasizing the importance of monitoring immune responses in clinical trials. They also explore the

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15:20

Redefining Acute Myeloid Leukemia (AML) Treatment!!!...

BioTech Nation ... with Dr. Moira Gunn ·

2024/03/27

This week I speak with Dr. Robert Ang from Vor Biopharma about their innovative approach to treating acute myeloid leukemia (AML). AML is a type of blood cancer that affects the bone marrow, leading to the overgrowth of cancerous cells. Dr. Ang explains that traditional treatments, such as chemotherapy and stem cell transplants, have limitations and risks. Dr. Ang emphasizes the potential of their treatment to revolutionize AML therapy and improve patient outcomes.

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155 results

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