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PODCAST

Daily Value

William Wallace, Ph.D.

Daily Value is a podcast examining the biological foundations of human function. Hosted by Dr. William Wallace, episodes explore nutrition, supplementation, and related health topics through the lens of biochemistry, physiology, and human evidence

health & fitness alternative health

All Episodes

11:09

How Vitamin K Could Play a Role in Brain Health

Daily Value ·

2024/09/23

In today’s episode of Daily Value, we explore the possibly underappreciated role of vitamin K in brain health and neuroprotection. Recent research (doi: 10.3389/fnut.2024.1396707) reveals a connection between dietary vitamin K intake and reduced levels of neurofilament light chain, a potential biomarker for neurodegeneration, particularly in middle-aged and older adults. We’ll discuss how vitamin K supports neuronal function, what specific forms of vitamin K are most important, and how this n...

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9:41

The Power of Magnesium: Unlocking its Potential to...

Daily Value ·

2024/09/20

In today’s episode of Daily Value, we explore the relationship between magnesium supplementation and blood pressure management. Although past research has produced mixed results, a recent umbrella meta-analysis (PMID: 39280209) has provided new insights into the impact of magnesium on cardiovascular health. With hypertension being a major risk factor for heart disease and stroke, understanding how magnesium can help regulate blood pressure is more important than ever.Episode Talking Poi...

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15:43

Can Diet and Supplements Aid Traumatic Brain Injury...

Daily Value ·

2024/09/18

In today’s episode of Daily Value, we explore the complex and ever-evolving topic of Traumatic Brain Injuries (TBIs), with a focus on new findings related to nutritional support and recovery. TBIs are often referred to as "invisible injuries" due to their [at times] subtle presentation, but they can have long-lasting effects on brain health and function. Recent research suggests that targeted supplementation may aid in recovery and even mitigate some of the long-term impacts of TBIs. Epi...

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8:46

Boosting Brain Power: Nicotinamide Riboside Elevates...

Daily Value ·

2024/09/16

In today’s episode of Daily Value, we look at new research that highlights how Nicotinamide Riboside supplementation, for the first time, was shown to elevate NAD+ levels in the brain, with potential implications for cognitive health and longevity. Episode Talking Points:*Mechanisms through which NAD+ supports brain health, including its role in DNA repair, energy production, and neuroprotection.*Key findings from a recent study showing a 16% average increase in cerebral NAD+ levels just...

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10:45

Taurine: From Energy Drinks to Cardiovascular...

Daily Value ·

2024/09/13

In today’s episode of Daily Value, we explore new research that affirms taurine's heart benefits, focusing on its effects on heart rate, blood pressure, and heart function in healthy and conditioned populations. Taurine is thought to be the most abundant amino acid in the heart, accounting for approximately 50% of the total free amino acids in this organ. As such, it’s no surprise that taurine plays a critical role in cardiovascular physiology. To some taurine may be associated with energy dr...

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7:40

How Ashwagandha Might Elevate Your VO2 Max

Daily Value ·

2024/09/11

In the latest episode of Daily Value, we explore new research on Ashwagandha’s potential to enhance physical performance, focusing on its ability to increase VO2 max, based on a recent eight-week randomized controlled trial (PMID: 38988644). Traditionally known for stress reduction, Ashwagandha is emerging as a interesting supplement with potential for improving endurance and aiding recovery.Talking Points:Can Ashwagandha help improve VO2 max and overall endurance?Theoretical mechanisms invol...

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11:29

Could Creatine Boost Brain Power and Cognitive Function?

Daily Value ·

2024/09/09

In the latest episode of Daily Value, we look at new research on creatine monohydrate's potential to enhance cognitive function, based on a recent meta-analysis published in Frontiers in Nutrition (PMID: 39070254). Traditionally used for its athletic performance benefits, creatine is now emerging as a promising supplement for brain health and cognitive enhancement.Talking Points:*Does creatine supplementation enhance cognitive function(s)?*Theoretical mechanisms: creatine enhances brain ATP l...

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8:35

The Hidden Global Crisis: Micronutrient Deficiencies...

Daily Value ·

2024/09/06

In the latest episode of Daily Value, we dive into the global crisis of micronutrient inadequacies, based on research published in The Lancet Global Health. This study provides the first-ever global estimates on inadequate consumption of 15 essential micronutrients, revealing widespread deficiencies impacting billions of people.Talking Points:Widespread Deficiencies: 68% of the global population lacks sufficient iodine intake, 67% are deficient in vitamin E, and 66% in calcium. Iron, ri...

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6:39

The Game-Changing Role of NAC in Heart Health

Daily Value ·

2024/08/30

N-acetyl cysteine (NAC) shows promise for heart attack preventionHeart attacks and strokes are a leading cause of death in developed countries - accounting for ~20% of all deaths in the U.S. Frequently, heart attacks and strokes are caused by blood clots (blood platelets that form when they are not needed, causing a narrowing/blockage of blood vessels) formed through arterial thrombosis. Current antiplatelet agents (e.g., aspirin) are effective but can increase major bleeding risk. As s...

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8:32

The Surprising Benefits of Zinc Supplementation for...

Daily Value ·

2024/08/28

Zinc and the Common Cold: What You Need to KnowWhat does zinc do for the body? Zinc is an essential trace element vital for immune function, wound healing, and DNA synthesis. It supports over 300 enzymes and the proper function of immune cells like T-cells and macrophages. Zinc also aids in the production of antibodies that fight infections.A recent review in the Cochrane Database of Systematic Reviews found that zinc supplements might not prevent colds, but taking zinc at the onset of ...

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6:37

10-20% More Magnesium Supports Muscle Recovery in...

Daily Value ·

2024/08/26

Does magnesium supplementation reduce muscle soreness across various physical activities?a review paper published in the Journal of Translational Medicine explored the effects of magnesium supplementation on muscle soreness across different physical activities.Findings:*Reduction in muscle soreness: magnesium significantly reduced muscle soreness and improves feelings of recovery in subjects.*Performance enhancement: positive effects on performance metrics, including improved blood glucose le...

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9:05

Can Nutritional Psychiatry Offer New Solutions for...

Daily Value ·

2024/08/23

In this episode of Daily Value, we explore the potential of omega-3 fatty acids, particularly EPA and DHA, as an adjunctive therapy for reducing anxiety symptoms. A recent meta-analysis (PMID: 38890670) reviewed 23 randomized controlled trials involving over 2,100 participants, revealing that a certain amount of omega-3s per day can significantly reduce anxiety symptoms, especially when combined with traditional treatments like antidepressants.Talking points:Anxiety disorders: what are they a...

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9:42

The Science Behind Probiotics Enhancing B Vitamin...

Daily Value ·

2024/08/21

In this episode of Daily Value I cover recent research suggesting specific probiotic species may enhance the bioavailability of essential B-vitamins, offering insights into a [potentially] synergistic approach for optimizing metabolic and gut health.Covered in the episode- How some Lactobacillus species were shown to significantly increase the absorption of vitamins B1, B3, B5, and B12 in rodent models, despite these strains not being direct producers of B-vitamins.- Proposed mechanisms, incl...

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11:17

The Surprising Gut Health Benefits of B-Vitamins

Daily Value ·

2024/08/19

In this episode of Daily Value, we explore the recent findings on the role of B-group vitamins as potential prebiotic candidates and their effects on the human gut microbiome. The discussion is centered around some of the latest research, which highlights how these essential vitamins, traditionally known for their metabolic roles, are now being recognized for their ability to modulate the gut microbiome and how different bacterial species may also play key roles as B-vitamin Producers.The pot...

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8:53

One of the Most Overlooked Nutrients for Better Sleep

Daily Value ·

2024/08/16

Unlocking Better Sleep: The Tryptophan Amino Acid ConnectionTryptophan, an essential amino acid, is necessary in the synthesis of serotonin and melatonin, key regulators of sleep and circadian rhythms. A recent study published in Nutrients looked at the impact of dietary tryptophan intake on sleep quality among over 11,000 university students, a group notorious for erratic sleep patterns.The study revealed that students consuming the highest amounts of tryptophan (over 800 mgs/day) expe...

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8:23

Iron Deficiency in Athletes: The Hidden Barrier to...

Daily Value ·

2024/08/14

Iron may play a critical role in athletic performanceIron is a key component of hemoglobin and myoglobin, proteins responsible for oxygen transport and storage in muscles, essential during aerobic exercise. When you’re exercising, especially in endurance sports, your muscles need a constant supply of oxygen to produce the energy they need to keep going. This process, known as aerobic respiration, is heavily dependent on iron (iron is what bind oxygen for transport in the body).current recomme...

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9:21

This Amount (and Type) of Fish Oil May Protect...

Daily Value ·

2024/08/12

White matter, composed largely of myelinated nerve fibers, facilitates communication between different brain regions. Damage to white matter, observed (i.e., lesions) via MRI, is associated with cognitive decline and increased dementia risk. Plasma concentrations of omega-3 fatty acids in epidemiological research is associated with a reduced burden of white matter lesions (WML)An RCT published in Neurology (PMID: 39088212) this August looked at the effects of omega-3 supplementation on white ...

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28:01

December 2023 Research Roundup: Influencing Future...

Daily Value ·

2024/01/15

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69:16

Unlocking Energy: The Essential Role of "the First...

Daily Value ·

2024/01/01

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81:20

Understanding the Far-Reaching Effects of Vitamin A

Daily Value ·

2023/09/04

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