PODCAST

Pulmonary Medicine

ReachMD

science & medicine medicine

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00:00:00

An Update on COVID-19 Immunity with Arturo Casadevall

Pulmonary Medicine ·

2020/05/14

Host: Joshua Sharfstein, MD Guest: Arturo Casadevall, MD, PhD Dr. Arturo Casadevall—head of the convalescent plasma research project at Johns Hopkins—talks through the WHO’s recent statement that there’s no evidence of COVID-19 infection leading to short- or long-term immunity. Dr. Casadevall and Dr. Josh Sharfstein also discuss how COVID-19 is not like HIV or pneumonia and what we currently know about new strains of the novel coronavirus. Published May 6, 2020

00:00:00

An Emergency Medicine Expert Answers More of Your...

Pulmonary Medicine ·

2020/05/07

Host: Joshua Sharfstein, MD Guest: Lauren M. Sauer, MS What makes this virus different from hundreds of other similar viruses? What happens if parents don’t take their children for routine immunizations? Does prone body positioning help ICU patients? Does coronavirus spread best in wet or dry environments? What are randomized control trials and why is everyone talking about them? Is it possible to give someone a tattoo from six feet away? Lauren Sauer, Director of Operations with

00:00:00

Inside the Johns Hopkins Lab That Developed Its Own...

Pulmonary Medicine ·

2020/05/07

Host: Joshua Sharfstein, MD Guest: Karen C. Carroll, MD In March, Johns Hopkins Hospital began making its own COVID-19 tests. The lab now has the capacity to run 600 tests per day but is limited by shortages in the supply of reagents: the chemicals needed to process the tests. Dr. Karen Carroll, Director of the Division of Medical Microbiology at Johns Hopkins Hospital talks with Dr. Josh Sharfstein about what it takes to develop a working COVID-19 test, why labs across the US are

00:00:00

Cytokine Storms & COVID-19 Severity

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Maximilian Konig, MD Guest: Chetan Bettegowda, MD, PhD For the subset of people who become critically ill from the novel coronavirus, cytokine storms could be to blame. This severe inflammatory disease happens when the immune system goes haywire in response to a novel threat. Rheumatology fellow Dr. Max Konig and neurosurgeon Dr. Chetan Bettegowda talk with Stephanie Desmon about the vital role of cytokine in immune

00:00:00

Finding the Best “Cocktail” of Treatments for COVID-19

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Guest: Derek C. Angus, MD, MPH, FRCP Until there is a vaccine, the best hope for the novel coronavirus is finding the right “cocktail” of treatments for managing severe illness. A unique clinical trial model developed several years ago may now help identify treatments that work. Dr. Derek Angus talks to Dr. Josh Sharfstein about the Bayesian inference model, a “March Madness” of testing multiple therapies at once. Published April 27, 2020

00:00:00

Unlocking More Secrets of COVID-19: Seasonality, Flu...

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Andrew Stanley Pekosz, PhD Virologist Dr. Andrew Pekosz returns to the podcast with an update on what his team has learned about COVID-19. Dr. Pekosz and Stephanie Desmon discuss further indications that COVID-19 may not be seasonal, why COVID-19 is “the flu on steroids,” and how learning about how the virus replicates in our upper respiratory tracts could hold clues for treatment and prevention. PLUS: An update on the

00:00:00

Everything You Need to Know About Antibody Testing...

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Guest: Gigi Kwik Gronvall, PhD The market is suddenly flooded with antibody tests claiming to prove whether or not people have already been exposed to COVID-19. But two critical questions are yet unanswered: Are any of these tests accurate and does past exposure mean immunity? Immunologist Dr. Gigi Gronvall of the Johns Hopkins Center for Health Security talks to Dr. Josh Sharfstein about a new report outlining the potential and pitfalls of antibody

00:00:00

Dr. Jennifer Nuzzo Answers Even More of Your COVID-19...

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Guest: Jennifer Nuzzo, MD If bats are immune to the novel coronavirus, can we learn something to help fight the virus in humans? How can I tell if my cough is spring allergies or COVID-19? Is it too soon for businesses like barber shops and salons to reopen? Can the virus crawl or be blown by the wind into your nose? Why are some people asymptomatic? Dr. Jennifer Nuzzo of the Johns Hopkins Center for Health Security addresses questions. Published April

00:00:00

School Closures in the Time of COVID-19

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Annette C. Anderson, PhD Most schools closed suddenly and have had to scramble to stand up online learning or other solutions to continue instruction in the midst of the pandemic. Further complicating the response is the fact that no one knows how long this will last. Dr. Annette Anderson of the Johns Hopkins School of Education talks to Stephanie Desmon about the Digital Divide, how schools are trying to prevent a

00:00:00

What’s Next with COVID-19: Considerations for...

Pulmonary Medicine ·

2020/05/01

Host: Joshua Sharfstein, MD Guest: Caitlin Rivers, PhD, MPH Much of our world was suddenly postponed, canceled, or shuttered in the last month or so. There’s now an opportunity to be more thoughtful about reopening. There are risks either way: wait too long and there are consequences for health, safety, and the economy. Open too soon, and viral transmission may ramp up and out of control. Dr. Caitlin Rivers of the Center for Health Security is coauthor of a recent report geared

00:00:00

Fast-Tracking Coronavirus Solutions

Pulmonary Medicine ·

2020/04/24

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Julie Messersmith Guest: Denis Wirtz The challenges presented by the pandemic are giving rise to a pipeline of research proposals focused on COVID-19. Julie Messersmith and Denis Wirtz are leading Johns Hopkins University's multidisciplinary research projects to develop better detection and protection tools and treatments for COVID-19 patients. They talk to Stephanie Desmon about how engineers, public health

00:00:00

FDA Issuance on Chloroquine & Hydroxychloroquine for...

Pulmonary Medicine ·

2020/04/24

Host: Linda Bernstein, Pharm.D. The US Food and Drug Administration has authorized clinicians to prescribe chloroquine and hydroxychloroquine for hospitalized patients with COVID-19, despite warnings from scientific advisers that no randomized controlled trial has been conducted to support the drugs’ safety and efficacy in this population. Pharmacist Dr. Linda Bernstein takes us through the FDA’s decision process, the parameters of the issuance, and comments made by the experts on this

00:00:00

Coagulopathy in COVID-19: Cause or Effect?

Pulmonary Medicine ·

2020/04/24

Host: Linda Bernstein, Pharm.D. Join pharmacist Dr. Linda Bernstein as she highlights several articles from recent literature describing coagulopathies in severely ill COVID-19 patients in China. She explores the cause and effect theories behind these findings and whether the observed coagulopathies are due directly to the virus, the critically ill condition of the patient that predisposes them to thromboembolism, or some combination of the two. Published April 24, 2020

00:00:00

The DEA’s Adjustment to Schedule II Rules Amid COVID-19

Pulmonary Medicine ·

2020/04/24

Host: Linda Bernstein, Pharm.D. The Drug Enforcement Administration (DEA) issued a new guidance for the issuance of oral Schedule II prescriptions in light of the COVID-19 pandemic and nationwide public health emergency. Pharmacist Dr. Linda Bernstein details the DEA’s temporary exceptions to the regulations to ease prescribing and dispensing of these controlled substances during this challenging time. Published April 24, 2020

00:00:00

Back to School? Reopening a University During the...

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Guest: Preeti N. Malani MD Colleges and universities are already starting to think about what it would take to reopen for the fall semester. But bringing back students, faculty, and staff—and welcoming the class of 2024—will require a complete rethinking of campus life. Dr. Preeti Malani, Chief Health Officer of the University of Michigan, talks to Dr. Josh Sharfstein about how she’s considering the health and safety of 50,000 students plus faculty and

00:00:00

You Asked Questions About Coronavirus, Tom Inglesby...

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Guest: Tom Inglesby, MD Does the virus cause male sterility? Are false negatives a problem with COVID tests? Is there a connection between how much virus you’re exposed to and how serious the illness is? Should people on immunosuppressive drugs stop taking them? Does the virus “reactivate?” Can people really become immune? Why are there so many more cases in the northern hemisphere? Why will a COVID-19 vaccine take so long when we come up with a new flu

00:00:00

Bare Shelves: Is the Food System Threatened by COVID-19?

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Roni Neff Bare shelves in grocery stores feed pandemic anxiety but Roni Neff, an expert on food systems and public health at the Johns Hopkins Center for a Livable Future, says this is not the biggest concern. Neff talks to Stephanie Desmon about how our robust food industry depends largely upon keeping its workers safe and well, how a pandemic completely shifts the model of emergency food access, and what’s being done

00:00:00

“Identify Every Case”: Successful Contact Tracing &...

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Crystal R. Watson, DrPH Contact tracing is a core tool of public health. Now, it could be a way to reopen the world. Crystal Watson of the Center for Health Security is the lead author of a recent report with a national plan to scale up our capability to conduct contact tracing. Watson talks to Stephanie Desmon about what contact tracing entails, how technology could help, how to approach privacy concerns, and why the

00:00:00

COVID-19’s Particular Threat to Native American...

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Allison Barlow, PhD Poor health care, lacking infrastructure, and generational poverty combine to make Native Americans especially vulnerable to COVID-19. With previous infectious respiratory illnesses like H1N1, mortality rates were sometimes four to five times higher than US averages among tribal communities. Allison Barlow, Director of the Center for American Indian Health, talks to Stephanie Desmon about COVID-19’s

00:00:00

The Rise of Zoonotic Diseases Like COVID-19 & Risks...

Pulmonary Medicine ·

2020/04/23

Host: Joshua Sharfstein, MD Host: Stephanie Desmon Guest: Meghan F. Davis, PhD, DVM Most new diseases originate from “spillover events” where humans come into contact with wild animals. Veterinarian and scientist Meghan Davis talks to Stephanie Desmon about the rise of infectious diseases and what is being done to prepare for future spillover events. She also covers how a tiger in the Bronx Zoo got a test, and the threats COVID-19 may pose to your own pets. Published April 14,

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