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PODCAST

NEJM This Week

Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.

health & fitness medicine

All Episodes

28:13

NEJM This Week — August 15, 2024

NEJM This Week ·

2024/08/14

Featuring articles on osimertinib in stage III EGFR-mutated lung cancer, cognitive motor dissociation in disorders of consciousness, rapid deployment of a brain–computer interface in ALS, and the longevity of a brain–computer interface for ALS; a review article on the genetics of chronic kidney disease; a case report of a boy with autism and decreased vision; and Perspectives on medical expertise, on collecting data on sexual orientation and gender identity, and on the pursuit of polka dots.

en-US

33:12

NEJM This Week — August 8, 2024

NEJM This Week ·

2024/08/07

Featuring articles on crinecerfont in pediatric and adult congenital adrenal hyperplasia, the postacute sequelae of SARS-CoV-2 infection, and nipocalimab in early-onset severe hemolytic disease of the fetus and newborn; a review article on frailty in older adults; a case report of a woman with postpartum anxiety and intrusive thoughts; and Perspectives on refusing to learn the lessons of Covid-19; on preparing for the next pandemic; on collective trauma and commemoration; and on an unknown family

en-US

30:01

NEJM This Week — August 1, 2024

NEJM This Week ·

2024/07/31

Featuring articles on belantamab mafodotin for multiple myeloma, autoantibodies targeting nephrin in podocytopathies, neutralizing anti–interleukin-10 autoantibodies in IBD; a review article on Parkinson’s disease; a Clinical Problem-Solving on going down the rabbit hole; a Medicine and Society article on race-based screening under the ethics microscope; and a Perspective on a legacy of cruelty to sexual and gender minority groups.

en-US

26:34

NEJM This Week — July 25, 2024

NEJM This Week ·

2024/07/24

Featuring articles on treatments for metabolic dysfunction–associated steatohepatitis, blinatumomab in adults with ALL, and sotorasib for KRAS G12C–driven vascular malformations; a review article on HIV-associated tuberculosis; a case report of a woman with rapidly progressive dementia; and Perspectives on the abandonment of people subjected to sexual and intimate partner violence, on multicancer early detection tests, and on coping in the setting of serious illness.

en-US

30:29

NEJM This Week — July 18, 2024

NEJM This Week ·

2024/07/17

Featuring articles on tenecteplase for ischemic stroke within 4.5 to 24 hours after the stroke, risankizumab vs. ustekinumab for Crohn’s disease, nirmatrelvir–ritonavir as Covid-19 postexposure prophylaxis, and efanesoctocog alfa in children with hemophilia A; a review article on the management of insomnia; a case report of a woman with postpartum fever, abdominal pain, and skin ulcers; and Perspectives on the ethics of relational AI, on anticipating the next pandemic, and on a first patient.

en-US

36:25

NEJM This Week — July 11, 2024

NEJM This Week ·

2024/07/10

Featuring articles on semaglutide and chronic kidney disease in type 2 diabetes, felzartamab in kidney-transplant rejection, bulevirtide and peginterferon for chronic hepatitis D, and nirsevimab and hospitalization for RSV bronchiolitis; a review article on malnutrition in adults; a case report of an infant with vomiting and hypercalcemia; and Perspectives on Medicare Advantage and consolidation’s new frontier, on orphan drugs and priorities for the future, on funding post-authorization

en-US

31:45

NEJM This Week — July 4, 2024

NEJM This Week ·

2024/07/03

Featuring articles on stress ulcer prophylaxis during invasive mechanical ventilation, new therapies for hereditary angioedema, tissue factor–directed therapy in cervical cancer, and normalization of C1 inhibitor in a patient with hereditary angioedema; a review article on acute abdomen in the modern era; a Clinical Problem-Solving article on aggregating the loose threads; a Medicine and Society on a case for the Medical Civil Rights Act; and Perspectives on academic freedom in America; on water

en-US

33:34

NEJM This Week — June 27, 2024

NEJM This Week ·

2024/06/26

Featuring articles on treatments for eosinophilic esophagitis, reteplase versus alteplase for acute ischemic stroke, dupilumab for COPD with type 2 inflammation, and brigatinib in NF2-related schwannomatosis; a review article on amyloidosis; a case report of a man with recurrent fever and liver lesions; and Perspectives on Alzheimer’s disease, biomarkers, and mAbs; on climate litigation for protecting public health; on carbon-footprint analyses in RCTs; and on the phantom of the organ.

en-US

33:09

NEJM This Week — June 20, 2024

NEJM This Week ·

2024/06/19

Featuring articles on combination therapy for diffuse large B-cell lymphoma, autosomal dominant Alzheimer’s disease, noninvasive ventilation for preoxygenation during emergency intubation, a novel anti-CD38 antibody in immune thrombocytopenia, and a glucose-responsive insulin for type 2 diabetes; a review article on congenital and acquired Chiari syndrome; a case report of a man with arthritis and rash; and Perspectives on ethics and innovative research on brain diseases, on sustaining and scaling

en-US

28:19

NEJM This Week — June 13, 2024

NEJM This Week ·

2024/06/12

Featuring articles on T-cell cancer after CAR T-cell therapy, the early diagnosis and treatment of COPD and asthma, and the implications of race adjustment in lung-function equations; a review article on diets; a case report of a woman with the worst headache of her life; and Perspectives on efforts toward equity and on feeling guilty.

en-US

23:32

NEJM This Week — June 6, 2024

NEJM This Week ·

2024/06/05

Featuring articles on neoadjuvant immunotherapy for dMMR colon cancer, TAVR in patients with a small aortic annulus, gene editing and retinal degeneration, and the genetic diagnosis of rare diseases; a review article on disorders of magnesium; a case report of a woman with metastatic breast cancer; and a Perspective on malicious midwives, fruitful vines, and bearded women.

en-US

39:49

NEJM This Week — May 30, 2024

NEJM This Week ·

2024/05/29

Featuring articles on aficamten for obstructive hypertrophic cardiomyopathy; early blood-pressure reduction in acute stroke; interferon-γ in autoimmune polyendocrine syndrome type 1; video laryngoscopy for intubation in neonates; hunger, thirst, and Buridan’s ass; and global health law for a safer and fairer world; a review article on medical AI and human values; a case report of a man with a pustular rash; and Perspectives on an approach toward a tobacco-free generation, on fair allocation of GLP-1

en-US

36:04

NEJM This Week — May 16, 2024

NEJM This Week ·

2024/05/15

Featuring articles on andexanet and factor Xa inhibitor–associated hemorrhage, perioperative nivolumab in resectable lung cancer, olezarsen for familial chylomicronemia syndrome, and olezarsen for hypertriglyceridemia; a review article on climate change, extreme heat, and health; a case report of a woman with worsening rash; and Perspective articles on focusing on health care equity, on underestimated challenges for social care initiatives, on integrating public health and health care, and on

en-US

31:07

NEJM This Week — May 9, 2024

NEJM This Week ·

2024/05/08

Featuring articles on gene editing in severe sickle cell disease and in transfusion-dependent β-thalassemia, thrombectomy for stroke with a large infarct, and recombinant ADAMTS13 in life-threatening immune thrombotic thrombocytopenic purpura; a review article on taste physiology; a case report of a woman with back pain, leg stiffness, and falls; and Perspective articles on the public good on the docket, on reengineering addiction, on welcoming the era of gene editing in medicine, and on all’s fair

en-US

25:57

NEJM This Week — May 2, 2024

NEJM This Week ·

2024/05/01

Featuring articles on a monoclonal antibody to prevent malaria, apolipoprotein A1 and outcomes after myocardial infarction, transcatheter or surgical treatment of aortic-valve stenosis, and recombinant ADAMTS13 in congenital thrombotic thrombocytopenic purpura; a review article on cryptococcal disease in diverse hosts; a Clinical Problem-Solving on the meat of the matter; and a Perspective on Journal voices in the civil rights era.

en-US

31:32

NEJM This Week — April 25, 2024

NEJM This Week ·

2024/04/24

Featuring articles on empagliflozin after acute myocardial infarction, CD7 CAR T cells with allogeneic stem-cell transplantation, FFR-guided complete revascularization for STEMI, and nutrition for moderate-to-late preterm infants; a review article on age-related hearing loss; a case report of a man with leg weakness; and Perspective articles on hospital consolidation and physician unionization, on the myth of the free market for pharmaceuticals, and on going beyond code status.

en-US

33:00

NEJM This Week — April 18, 2024

NEJM This Week ·

2024/04/17

Featuring articles on adjuvant pembrolizumab after surgery in renal-cell carcinoma, beta-blockers after MI with preserved ejection fraction, a microaxial flow pump for STEMI and cardiogenic shock, and semaglutide in patients with heart failure and diabetes; a review article on retinoblastoma; a case report of a woman with confusion, aphasia, and abnormal head imaging; and Perspectives on expanding applications of clinical genetic testing, on twenty-five years after Columbine, on advocating for a

en-US

36:44

NEJM This Week — April 11, 2024

NEJM This Week ·

2024/04/10

Featuring articles on alectinib in ALK-positive lung cancer, minimally invasive removal of cerebral hematomas, and CAR T-cell–mediated responses in recurrent glioblastoma; a review article on energy and macronutrients across the life span; a case report of a woman with falls and cognitive decline; a Medicine and Society on money as medicine; and Perspectives on back to the future in Alabama, on the end of B/Yamagata influenza transmission, and on the plight of DEI leaders.

en-US

28:55

NEJM This Week — April 4, 2024

NEJM This Week ·

2024/04/03

Featuring articles on omitting axillary dissection in breast cancer with sentinel-node metastasis, a trial of lixisenatide in early Parkinson’s disease, nirmatrelvir–ritonavir in outpatients with Covid-19, and hospitalization for chronic kidney disease; a review article on the prevention of cardiovascular disease in type 1 diabetes; a case report of a woman with hyperglycemia refractory to insulin; and a Perspective article on Nazism and the Journal.

en-US

30:56

NEJM This Week — March 21, 2024

NEJM This Week ·

2024/03/20

Featuring articles on autism and prenatal exposure to antiseizure medication, ribociclib plus endocrine therapy in early breast cancer, gene therapy for giant axonal neuropathy, and anti–interleukin-23 in immunodeficiency; a review article on wearable digital health technologies in clinical care; a case report of a man with a fall; and Perspective articles on physicians, spirituality, and compassionate care; on the risks posed by immediate release of test results to patients; and on what one author

en-US

94 results

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