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PODCAST

Supersized Science

Texas Advanced Computing Center - University of Texas at Austin

The Supersized Science podcast highlights research and discoveries nationwide enabled by advanced computing technology and expertise at the Texas Advanced Computing Center of the University of Texas at Austin. TACC science writer Jorge Salazar hosts Supersized Science.

science & medicine natural sciences

All Episodes

15:41

Complete Coronavirus Model

Supersized Science ·

2021/03/04

Frontera, Anton 2 supercomputers simulate holistic model of SARS-CoV-2 virion

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26:44

Targeting the Deadly Coils of Ebola

Supersized Science ·

2021/01/21

In the midst of a global pandemic with COVID-19, it’s hard to appreciate how lucky those outside of Africa have been to avoid the deadly Ebola virus disease. It incapacitates its victims soon after infection with massive vomiting or diarrhea, leading to death from fluid loss in about 50 percent of the afflicted. The Ebola virus transmits only through bodily fluids, marking a key difference from the COVID-19 virus and one that has helped contain Ebola’s spread. Ebola outbreaks continue to flare up in

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26:44

Targeting the Deadly Coils of Ebola

Supersized Science ·

2021/01/21

Stampede2, Bridges supercomputer simulations show weak spots in Ebola virus nucleocapsid

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19:01

Corona's Ladder

Supersized Science ·

2020/07/27

The coronavirus infects its host cell by first binding one of its spike proteins and then fusing its helical core to the host cell. The virus makes its own molecular version of the mythical Jacob’s Ladder that reaches for the heavens. It builds a far-reaching ladder-like apparatus from core helical amino acids that latch on to its host cell, leading to infection. Scientists don’t yet fully understand the details of how the coronavirus binds and fuses. Numan Oezguen is an instructor at the Microbiome

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19:01

Corona's Ladder

Supersized Science ·

2020/07/27

Computer model simulating binding and fusing dynamics of the coronavirus on Longhorn, a subsystem of the Frontera supercomputer at the Texas Advanced Computing Center. Research supported by the COVID-19 High Performance Computing Consortium.

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17:52

Sugar Coating Locks And Loads Coronavirus For Infection

Supersized Science ·

2020/07/27

NSF-funded Frontera supercomputer at TACC used for simulations that animated the molecular dynamics of the 1.7 million atom coronavirus spike protein system.

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17:52

Sugar Coating Locks And Loads Coronavirus For Infection

Supersized Science ·

2020/07/27

They say you can’t judge a book by its cover. But the human immune system does just that when it comes to finding and attacking harmful microbes such as the coronavirus. It relies on being able to recognize foreign intruders and generate antibodies to destroy them. Unfortunately, the coronavirus uses a sugary coating of molecules called glycans to camouflage itself as harmless from the defending antibodies. Simulations on the National Science Foundation (NSF)-funded Frontera supercomputer at the

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10:01

Coronavirus Massive Simulations Completed on Frontera...

Supersized Science ·

2020/03/30

Scientists prepared a massive computer model of the coronavirus expected to give insight into how it infects. They've tested the first parts of the model and optimizing code on the Frontera supercomputer at the Texas Advanced Computing Center of UT Austin

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10:01

Coronavirus Massive Simulations Completed on Frontera...

Supersized Science ·

2020/03/30

Scientists are preparing a massive computer model of the coronavirus that they expect will give insight into how it infects in the body. They’ve taken the first steps, testing the first parts of the model and optimizing code on the Frontera supercomputer at the Texas Advanced Computing Center of UT Austin. The knowledge gained from the full model can help researchers design new drugs and vaccines to combat the coronavirus. Podcast host Jorge Salazar interviews Rommie Amaro, a professor of chemistry

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15:09

Supercomputers Drive Ion Transport Research

Supersized Science ·

2020/03/04

For scientists, natural systems can try one’s patience. For a long time, nothing. Then all of a sudden, something. Wonderful things in nature can burst on the scene after long periods of dullness - rare events such as protein folding, chemical reactions, or even the seeding of clouds. Path sampling techniques employ computer algorithms that deal with the dullness in data by focusing on transitions. Scientists are using supercomputers to help understand the relatively rare event of salts in water

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15:09

Supercomputers Drive Ion Transport Research

Supersized Science ·

2020/03/04

TACC's Stampede2 supercomputer powers path-sampling molecular simulations

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22:20

Simulations Reveal Galaxy Clusters Details

Supersized Science ·

2020/02/06

Galaxy clusters probed with Stampede2, Comet Supercomputers

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22:20

Simulations Reveal Galaxy Clusters Details

Supersized Science ·

2020/02/06

The spacefaring Romulans of Star Trek science fiction have inspired some astrophysicists to develop cosmological simulations called RomulusC, where the ‘C’ stands for galaxy cluster. With a focus on black hole physics, RomulusC has produced some of the finest resolution simulations ever of galaxy clusters, which can contain hundreds or even thousands of galaxies. On Star Trek, the Romulans powered their spaceships with an artificial black hole. In reality, it turns out that black holes can drive the

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20:08

Skin Cancer Mystery Revealed in Yin and Yang Protein

Supersized Science ·

2019/12/18

Scientists are using powerful supercomputers to uncover the mechanism that activates cell mutations found in about 50 percent of melanomas, the most serious type of human skin cancer because it can spread throughout the body. The scientists say they’re hopeful their study can help lead to a better understanding of skin cancer and to the design of better drugs. On the podcast are Yasushi Kondo and Deepti Karandur, both postdoctoral researchers in the John Kuriyan Lab at UC Berkeley. Karandur is also

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20:08

Skin Cancer Mystery Revealed in Yin and Yang Protein

Supersized Science ·

2019/12/18

Scientists used supercomputers to uncover the mechanism that activates cell mutations found in about 50% of melanomas. XSEDE allocations on TACC's Stampede2 and Bridges at PSC modeled the B-Raf protein and others in the pathway linked to skin cancer.

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9:21

Frontera Helps the Science That Transforms Society

Supersized Science ·

2019/09/16

TACC Podcast interviews Fleming Crim, COO of National Science Foundation

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9:21

Frontera Helps the Science That Transforms Society

Supersized Science ·

2019/09/16

The Texas Advanced Computing Center (TACC) celebrated the official launch of its newest supercomputing system, Frontera, funded by a $60 million award from the National Science Foundation. Frontera aims to help scientists with the cyberinfrastructure resources to tackle some of the biggest unknowns in science. And it’s made a promising start, with an initial rank of #5 fastest supercomputer in the world and #1 fastest academic system, according to the June 2019 Top500 rankings. Fleming Crim, the

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4:59

UT Austin President Greg Fenves On The Frontera...

Supersized Science ·

2019/09/08

UT Austin achieves leadership role in high performance computing for science with Frontera system

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4:59

UT Austin President Greg Fenves On The Frontera...

Supersized Science ·

2019/09/08

The University of Texas at Austin has claimed a leadership role in supercomputing with the top academic system in the world, Frontera, located at the Texas Advanced Computing Center (TACC). The National Science Foundation awarded TACC $60 million for building and operating Frontera, the fifth fastest computer in the world according to the June 2019 Top500 rankings. Frontera’s dedication event on September 3, 2019 was marked by an address from UT Austin President Greg Fenves. TACC podcast host Jorge

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15:02

Science On Repeat - Computational Reproducibility

Supersized Science ·

2019/04/19

TACC enhances computational reproducibility

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221 results

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