This Week in Neuroscience

Bob Datta joins TWiN to reveal the findings of his laboratory on expression of SARS-CoV-2 entry genes in the olfactory epithelium and the implications for anosmia associated with COVID-19. Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, Erin Calipari and Vincent Racaniello Guest: Bob Datta Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Expression of SARS-CoV-2 entry genes in nasal olfactory epithelium (bioRxiv) Expression of SARS-CoV-2

Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons. Hosts: Andres Bendesky, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Arc is a repurposed retrotransposon gag protein that mediates intercellular RNA transfer (Cell) Drosophila gag-like ARC1 (Cell) Letters read on TWiN #4 Timestamps by Jolene. Thanks! Intro

Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction. Hosts: Ori Lieberman, Erin Calipari,Jason Shepherd, and Vincent Racaniello Click arrow to play Download TWiN 003 (52 MB .mp3, 86 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Dopamine neurons encode reward probability and uncertainty (Science) Letters

The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing. Hosts: Ori Lieberman, Andres Bendesky,Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Bendesky lab Recycling Endosomes Supply AMPA Receptors for LTP (Science) AMPA

The synaptics launch the first episode of TWiN by revealing their training, research interests, and goals for the podcast. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello Become a patron of TWiN! Links for this episode Lieberman lab Calipari lab Shepherd lab Image credit Intro music is by Ronald Jenkees. Send your neuroscience questions and comments to twin@microbe.tv