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PODCAST

Empowered Patient Podcast

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

health & fitness medicine

All Episodes

0:00

Addressing Extracellular Matrix Breakdown That Leads...

Empowered Patient Podcast ·

2024/09/24

Dr. Sherif Idriss is the CEO of Elastin Biosciences, a company focused on targeting aging-related diseases by restoring elastin, a key protein in the extracellular matrix that provides elasticity and resilience to organs and tissues. They are developing small molecule therapies for diseases linked to elastin deficiency, including Williams syndrome and abdominal aortic aneurysm. As elastin degrades over time due to aging, it leads to loss of tissue structural integrity and function, contributing to

en

17:55

Addressing Extracellular Matrix Breakdown That Leads...

Empowered Patient Podcast ·

2024/09/24

Dr. Sherif Idriss is the CEO of Elastin Biosciences, a company focused on targeting aging-related diseases by restoring elastin, a key protein in the extracellular matrix that provides elasticity and resilience to organs and tissues. They are developing small molecule therapies for diseases linked to elastin deficiency, including Williams syndrome and abdominal aortic aneurysm. As elastin degrades over time due to aging, it leads to loss of tissue structural integrity and function, contributing to

en

0:00

Treating Septic Shock with Nanoparticle Formulation...

Empowered Patient Podcast ·

2024/09/23

Dr. Harven DeShield is the CEO and Co-Founder of Vivacelle Bio, which is developing a nanoparticle-based treatment called VBI-S to address the underlying causes of septic shock. The treatment works by efficiently redistributing nitric oxide to help regulate blood pressure and improve organ function, reducing the need for traditional vasopressor treatments. Vivacelle is also developing a product to help address hemorrhagic shock and minimize reperfusion injury. Harven explains, "There are seven

en

19:42

Treating Septic Shock with Nanoparticle Formulation...

Empowered Patient Podcast ·

2024/09/23

Dr. Harven DeShield is the CEO and Co-Founder of Vivacelle Bio, which is developing a nanoparticle-based treatment called VBI-S to address the underlying causes of septic shock. The treatment works by efficiently redistributing nitric oxide to help regulate blood pressure and improve organ function, reducing the need for traditional vasopressor treatments. Vivacelle is also developing a product to help address hemorrhagic shock and minimize reperfusion injury. Harven explains, "There are seven

en

0:00

Innovation in the EHR Landscape to Break Down Data...

Empowered Patient Podcast ·

2024/09/19

Sandra Johnson, the Senior Vice President of Client Services at CliniComp, discusses the evolving landscape of electronic health records (EHRs) and the need for interoperability and customization to meet clinicians' needs. She emphasizes the importance of putting clinicians first and involving them in the software development process from the beginning to create a configurable and user-friendly system. There are multiple ways to use AI and automation to improve EHRs, including predictive analytics,

en

17:23

Innovation in the EHR Landscape to Break Down Data...

Empowered Patient Podcast ·

2024/09/19

Sandra Johnson, the Senior Vice President of Client Services at CliniComp, discusses the evolving landscape of electronic health records (EHRs) and the need for interoperability and customization to meet clinicians' needs. She emphasizes the importance of putting clinicians first and involving them in the software development process from the beginning to create a configurable and user-friendly system. There are multiple ways to use AI and automation to improve EHRs, including predictive analytics,

en

0:00

How Pressure Mapping Technology is Revolutionizing...

Empowered Patient Podcast ·

2024/09/18

Kathy Gunn, VP of commercial and clinical operations at Wellsense, discusses the pressure mapping system Wellsense developed to prevent pressure injuries caused by support surfaces, offloading devices, and medical equipment. The pressure mapping technology works by installing an overlay into existing support surfaces, which sends real-time pressure readings and locations to an iPad-like device at the end of the bed. This visual feedback helps healthcare providers make better clinical decisions and

en

19:02

How Pressure Mapping Technology is Revolutionizing...

Empowered Patient Podcast ·

2024/09/18

Kathy Gunn, VP of commercial and clinical operations at Wellsense, discusses the pressure mapping system Wellsense developed to prevent pressure injuries caused by support surfaces, offloading devices, and medical equipment. The pressure mapping technology works by installing an overlay into existing support surfaces, which sends real-time pressure readings and locations to an iPad-like device at the end of the bed. This visual feedback helps healthcare providers make better clinical decisions and

en

0:00

Campaign to Promote Genetic and Biomarker Testing for...

Empowered Patient Podcast ·

2024/09/17

Jean Sachs, CEO of Living Beyond Breast Cancer, a national nonprofit organization dedicated to addressing disparities in cancer treatment and providing resources and support for individuals diagnosed with breast cancer. LBBC is part of the No One Missed breast cancer campaign, which aims to raise awareness about the importance of biomarker testing for metastatic breast cancer to help identify specific mutations in the tumor and develop a personalized treatment plan. Jean explains, "We are so proud

en

17:22

Campaign to Promote Genetic and Biomarker Testing for...

Empowered Patient Podcast ·

2024/09/17

Jean Sachs, CEO of Living Beyond Breast Cancer, a national nonprofit organization dedicated to addressing disparities in cancer treatment and providing resources and support for individuals diagnosed with breast cancer. LBBC is part of the No One Missed breast cancer campaign, which aims to raise awareness about the importance of biomarker testing for metastatic breast cancer to help identify specific mutations in the tumor and develop a personalized treatment plan. Jean explains, "We are so proud

en

0:00

Regeneration in the CNS to Recover Function from...

Empowered Patient Podcast ·

2024/09/16

Dr. Monica Perez, the Scientific Chair at the Arms and Hands Lab at the Shirley Ryan AbilityLab and Professor of Physical Medicine and Rehabilitation at Northwestern University, is focused on developing drugs and strategies for treating those with spinal cord injuries. With no FDA-approved treatment, the current standard of care is surgery and physical rehabilitation, depending upon the location of the injury and cause. The AbilityLab is conducting a clinical trial with NVG-291, which targets the

en

16:38

Regeneration in the CNS to Recover Function from...

Empowered Patient Podcast ·

2024/09/16

Dr. Monica Perez, the Scientific Chair at the Arms and Hands Lab at the Shirley Ryan AbilityLab and Professor of Physical Medicine and Rehabilitation at Northwestern University, is focused on developing drugs and strategies for treating those with spinal cord injuries. With no FDA-approved treatment, the current standard of care is surgery and physical rehabilitation, depending upon the location of the injury and cause. The AbilityLab is conducting a clinical trial with NVG-291, which targets the

en

0:00

Future of Prescription Digital Therapeutics with...

Empowered Patient Podcast ·

2024/09/13

Richard ‘RJ’ Kedziora, Co-Founder, CEO, and Chief People Officer at Estenda Solutions, emphasizes that usability is critical in developing successful digital therapeutics, and industry standards and interoperability are essential for data sharing and integration. A digital therapeutic can be prescribed by a physician and reimbursed by insurance companies. It is a digital health application that has undergone clinical trials and regulatory review to prevent, monitor, or treat physical or mental

en

17:27

Future of Prescription Digital Therapeutics with...

Empowered Patient Podcast ·

2024/09/13

Richard ‘RJ’ Kedziora, Co-Founder, CEO, and Chief People Officer at Estenda Solutions, emphasizes that usability is critical in developing successful digital therapeutics, and industry standards and interoperability are essential for data sharing and integration. A digital therapeutic can be prescribed by a physician and reimbursed by insurance companies. It is a digital health application that has undergone clinical trials and regulatory review to prevent, monitor, or treat physical or mental

en

0:00

Focusing on Synthetic Lethality and Targeting the DNA...

Empowered Patient Podcast ·

2024/09/12

Oren Gilad, President and CEO of Aprea Therapeutics, focused on the DNA damage response pathway, specifically targeting the ATR protein. ATR is a master regulator of DNA replication and is hyperactive in cancer cells, making it a potential Achilles heel for cancer therapy. By inhibiting ATR, cancer cells can be selectively targeted, while normal cells can tolerate lower levels of ATR activity. Synthetic lethality is applied when two genetic mutations are combined, leading to cell death, specifically

en

17:34

Focusing on Synthetic Lethality and Targeting the DNA...

Empowered Patient Podcast ·

2024/09/12

Oren Gilad, President and CEO of Aprea Therapeutics, focused on the DNA damage response pathway, specifically targeting the ATR protein. ATR is a master regulator of DNA replication and is hyperactive in cancer cells, making it a potential Achilles heel for cancer therapy. By inhibiting ATR, cancer cells can be selectively targeted, while normal cells can tolerate lower levels of ATR activity. Synthetic lethality is applied when two genetic mutations are combined, leading to cell death, specifically

en

0:00

How Providing In-Home Acute Care Services Reduces...

Empowered Patient Podcast ·

2024/09/11

Dr. Marcy Carty, President and Chief Medical Officer of myLaurel, emphasizes the need to change the model where hospitals are the safest place for medical care. MyLaurel's acute care services include pre-hospital care to prevent emergency room visits, care-at-home to help patients get discharged earlier, and post-hospitalization care to smooth the transition. They work with primary physicians and other care providers to ensure a coordinated approach and use technology in the home to perform

en

16:57

How Providing In-Home Acute Care Services Reduces...

Empowered Patient Podcast ·

2024/09/11

Dr. Marcy Carty, President and Chief Medical Officer of myLaurel, emphasizes the need to change the model where hospitals are the safest place for medical care. MyLaurel's acute care services include pre-hospital care to prevent emergency room visits, care-at-home to help patients get discharged earlier, and post-hospitalization care to smooth the transition. They work with primary physicians and other care providers to ensure a coordinated approach and use technology in the home to perform

en

0:00

Expanding Access to Vital Cardiac Screening with Dr....

Empowered Patient Podcast ·

2024/09/10

Dr. Waqaas Al-Siddiq, the CEO and Founder of Biotricity, focuses on remote patient monitoring for heart health with HeartSecure, the three-channel wearable device that collects continuous ECG data. This device provides a more comprehensive view of the electrical activity of the heart compared to other wearables like smartwatches and can help identify potential cardiac issues, especially those that are intermittent and asymptomatic. Used by cardiologists and now available as a home-based diagnostic,

en

18:32

Expanding Access to Vital Cardiac Screening with Dr....

Empowered Patient Podcast ·

2024/09/10

Dr. Waqaas Al-Siddiq, the CEO and Founder of Biotricity, focuses on remote patient monitoring for heart health with HeartSecure, the three-channel wearable device that collects continuous ECG data. This device provides a more comprehensive view of the electrical activity of the heart compared to other wearables like smartwatches and can help identify potential cardiac issues, especially those that are intermittent and asymptomatic. Used by cardiologists and now available as a home-based diagnostic,

en

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