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PODCAST

Clinical Chemistry Podcast

Association for Diagnostics and Laboratory Medicine

This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today"s clinical laboratory.

science chemistry

All Episodes

11:07

Current Evidence and Future Perspectives on the...

Clinical Chemistry Podcast ·

2015/04/20

Medical laboratories provide valuable services to aid in patient diagnosis and management, but systematic evidence of laboratory medicine's specific contribution to the overall process of healthcare is not easy to come by. Even the widely quoted claim that laboratory medicine results are responsible for a 70% of all clinical decisions seems to elude objective verification.

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15:25

Vitamin D: The More We Know, the Less We Know

Clinical Chemistry Podcast ·

2015/04/06

Over the past 20 years or so there have been several studies published showing an association between decreased concentrations of vitamin D in blood and the risks of cardiovascular disease, stroke, cancer, fractures, even overall mortality.

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08:12

FullIssueSummary April2015

Clinical Chemistry Podcast ·

2015/04/01

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09:33

Qualitative Point-of-Care Human Chorionic...

Clinical Chemistry Podcast ·

2015/03/30

Rapid urine pregnancy tests have been available for over 30 years. They can be performed in minutes and are used at home, in doctors' offices and in emergency rooms. Doctors in particular rely on these tests to rule out pregnancy in order to prevent fetal injury or death that could be caused by certain medical procedures or drugs.

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10:30

Adaptive learning and medical education

Clinical Chemistry Podcast ·

2015/03/23

Recently, the New England Journal of Medicine partnered with Area9 Learning, a physician-led pioneer in adaptive learning, to create a platform with smart technology that adapts to clinicians' learning goals and knowledge gaps to deliver the information they need to know.

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06:12

Validation of a Proposed Novel Equation for...

Clinical Chemistry Podcast ·

2015/03/17

Aggressive strategies to lower Low Density Lipoprotein cholesterol in circulation are recommended for prevention of cardiovascular events. Most often laboratories report LDL-cholesterol based on an equation using measured values of total cholesterol, HDL - cholesterol and triglycerides, the so called Friedewald calculation named after the first author who published that work in Clinical Chemistry back in 1972.

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08:41

Is This a Critical, Panic, Alarm, Urgent, or Markedly...

Clinical Chemistry Podcast ·

2015/03/09

Medical laboratories frequently encounter clinically unexpected results that require timely clinical evaluation because they may indicate an imminent life-threatening condition or a major clinical deterioration. Laboratories, therefore, need to identify and report such results sooner than they normally would, and have policies and procedures that minimize the possibility of patient harm due to delayed clinical attention. The concept of these so-called "panic values" was raised by George Lundberg in

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10:07

Proposed Regulatory Framework for Direct-to-Consumer...

Clinical Chemistry Podcast ·

2015/03/02

In December 2013 the genetics laboratory 23andMe stopped marketing direct-to-consumer disease predictive genetic testing in order to comply with a directive from the US Food and Drug Administration. The FDA's action was intended to protect the American public from questionable disease risk predictions.

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08:01

FullIssueSummary March2015

Clinical Chemistry Podcast ·

2015/03/01

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10:58

Learning from Our Mistakes: The Future of Validating...

Clinical Chemistry Podcast ·

2015/02/23

Big data now seems to be everywhere. Google search queries are used to predict flu outbreaks and airline statistics or mined to determine the best hour of which day to book plane tickets. Clinical laboratories can also benefit from these trends. Given the emerging importance of reproducible data analysis pipelines, one could think of a special group of trained big data experts that could be available to regulatory agencies and to clinical laboratories for review and auditing of their processes and

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04:33

Association of 1,5-Anhydroglucitol with Diabetes and...

Clinical Chemistry Podcast ·

2015/02/18

Hemoglobin A1c is widely used to monitor glycemic control and is now recommended for use in the diagnosis of diabetes. Although hemoglobin A1c has high reliability compared to the oral glucose tolerance test, there are certain settings in which such testing may be problematic and there is a growing interest in alternative markers of hyperglycemia.

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09:01

Moving beyond mean glycemia: 1,5-anhydroglucitol and...

Clinical Chemistry Podcast ·

2015/02/09

Although hemoglobin A 1 C has high reliability , there a re certain settings in which hemoglobin A1C testing is thought to be problematic. 1 , 5 - anhydroglucitol or 1,5 - deoxyglucose is a monosaccharide originating mainly fr om foods and closely resembles glucose in structure , but is usually excreted by the kidneys.

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08:15

Noninvasive Prenatal Testing for Wilson Disease by...

Clinical Chemistry Podcast ·

2015/02/03

Prenatal testing using blood specimens rather than more invasive sampling has been successfully used for common chromosome disorders and for clinically significant copy number variations . H owever , detecting single gene disorders which are caused by mutations remains an analytical challenge.

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12:57

The Landscape of MicroRNA, Piwi-Interacting RNA, and...

Clinical Chemistry Podcast ·

2015/02/03

Human saliva has been increasingly used for biomarker development to allow noninvasive detection of diseases. Extracellular RNA was discovered in saliva about 10 years ago, and since then the nature, origin , and characterization of salivary RNA have been actively pursued.

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08:13

FullIssueSummary February2015

Clinical Chemistry Podcast ·

2015/02/01

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13:43

Clinical Exome Performance for Reporting Secondary

Clinical Chemistry Podcast ·

2015/01/30

In the last year, multiple clinical studies have shown the diagnosti c power of testing a patient's exome. Clinical exome testing is now available at over a dozen clinical laboratories in the US , and has been performed for thousands of patients.

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09:25

Next Generation Sequencing in Clinical Diagnostics:...

Clinical Chemistry Podcast ·

2015/01/26

Next generation sequencing (NGS)13 technology, also known as massively parallel sequencing (MPS), is being incorporated rapidly to clinical laboratory testing. Current applications include detection of germline variants in inherited diseases, somatic variants in cancers, subpopulations of circulating cell-free DNA, and single viral or microbial genomes in infections or metamicrobial genomes in normal or altered human flora. Each application is unique and has its advantages and disadvantages.

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10:01

Chromosomal Instability in Cell-Free DNA Is a Serum...

Clinical Chemistry Podcast ·

2015/01/13

Extreme sports, extreme eating, extreme weight loss, extreme makeovers, just when you think you've heard it all, how about Extreme PCR?

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10:56

Refinement of Variant Selection for the LDL...

Clinical Chemistry Podcast ·

2015/01/12

Familial hypercholesterolemia is a genetic disorder characterized by increased plasma concentrations of low density lipoprotein cholesterol and premature symptoms of coronary heart disease. Early identification of at-risk individuals allows changes in lifestyle including dietary intervention and drug treatment. In the January 2015 issue of Clinical Chemistry, a Special Issue devoted to Molecular Diagnostics, a group of researchers in a multi-center study describes a genetic risk score procedure that

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18:20

Extreme PCR: Efficient and Specific DNA Amplification...

Clinical Chemistry Podcast ·

2015/01/12

Extreme sports, extreme eating, extreme weight loss, extreme makeovers, just when you think you've heard it all, how about Extreme PCR?

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1,086 results

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