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PODCAST

Depresh Mode with John Moe

John Moe, Maximum Fun

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people

health & fitness mental health

All Episodes

00:40:23

You’re Not Imagining It, Climate Change IS Messing...

Depresh Mode with John Moe ·

2025/06/09

As temperatures and sea levels rise, the effects of climate change are being felt in weather patterns, natural disasters, and in both public and personal mental health. We talk with Dr. Caroline Carney, President of Behavioral Health and Chief Medical Officer at Magellan Health in Phoenix about the connection between your mind and the dire conditions Earth is facing. She says the damage is being done by the traumatic effects of fires, floods, and other severe weather incidents but also by the

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00:52:11

Can a Bipartisan Congressional Caucus Save Mental...

Depresh Mode with John Moe ·

2025/06/02

Rep. Andrea Salinas (D-Ore.) is one of four chairs of the bipartisan Mental Health Caucus in the U.S. House of Representatives, a 93-member group of Republicans and Democrats pledging to fight stigma, improve accessibility, and generally make the country’s mental health better. But as the Trump administration floats huge cuts to Medicaid and other social services and as the tone of politics in America gets more divided and vitriolic, does a well-intentioned group like that really have a chance to

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00:45:29

Ethan Sacks and Daughter Naomi Tackle Mental Health...

Depresh Mode with John Moe ·

2025/05/26

Ethan Sacks is a veteran comics writer, having created stories for Marvel, DC, and numerous Star Wars comics. In the comic A Haunted Girl, Ethan enlisted his daughter Naomi as co-writer to tell a story much more personal than anything involving Star Wars or the Avengers. A Haunted Girl tells the story of Cleo, a character inspired by Naomi’s real life experiences in her teens dealing with depression, anxiety, and suicidality. She spent time in in-patient facilities and now, at 21, is doing better

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00:44:02

Felicia Day on Depression, Anxiety, Achievement,...

Depresh Mode with John Moe ·

2025/05/19

It would take an entire section of show notes here to list all the things Felicia Day has accomplished in her career. Here’s an attempt at making that brief: acted in a bunch of TV shows you know, created and starred in web series, made just so very many online videos, and is now the author and star of an audiobook called Third Eye about someone who is supposed to save the world but fails. In our interview, Felicia talks about doing all those things while dealing with mental disorders like

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00:41:21

The Head And The Heart’s Kenny Hensley Injured Both...

Depresh Mode with John Moe ·

2025/05/12

Aperture is the sixth studio album by the indie-folk band The Head And The Heart and it’s kind of a return to the more grounded, collaborative sound of their earliest work. It’s less polished, less highly produced, not as poppy. That’s not an accident. The band has been putting in the work to be more of a cohesive unit by sharing songwriting and singing duties, going to therapy together, and trying to closely protect the health of both the individual members and the group itself. Kenny Hensley joins

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00:38:38

988’s Future, Funding, and Online Fables

Depresh Mode with John Moe ·

2025/05/05

There have been ten million contacts, via phone calls, texts, and chats, with the 988 Suicide & Crisis Lifeline since it first launched in July of 2022. As its third anniversary approaches, we check in to see how the system is holding up, what the funding and capacity issues are, and what the future might look like with our guest, Hannah Wesolowski, Chief Advocacy Officer for the National Alliance on Mental Illness (NAMI). We also examine the potential threat to the LGBTQ specialized services line

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00:47:45

Generative AI Chatbot Delivers Great Results for...

Depresh Mode with John Moe ·

2025/04/28

Would you open your heart to a bot? Tell it all your problems? Look to a piece of code, a computer program, for high-quality mental healthcare? Some people have said yes and the results are hard to ignore. Dartmouth University test subjects who sought help from Therabot, a generative AI chatbot, showed a 51% reduction in depression symptoms, 31% for anxiety, 19% for eating disorders. Dr. Nicholas Jacobson, who led the study, says people really bonded with Therabot, called it Thera for short, and

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00:48:24

Perfectly Hidden Depression: Do You Have It? With Dr....

Depresh Mode with John Moe ·

2025/04/21

If you were brought up in a family or a culture that never recognized, discussed, or processed things like depression and trauma, you may have learned to simply hide those difficult feelings away and simply act as if everything’s great. You can be a high achiever, striving perfection, all to keep away demons that you’ve never really faced. Your act can be so good that it even fools you. For a while, anyway. Until it doesn’t. And then things can get very ugly. Psychologist Dr. Margaret Rutherford

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00:44:05

Cameron Esposito on Comedy, Rehab, and Bipolar Disorder

Depresh Mode with John Moe ·

2025/04/14

Cameron Esposito has many titles: hugely successful standup comedian, actor in television and film, writer, podcast host. After a recent rehab stay led to a mental health diagnosis, she has realized that she’s also a person with bipolar disorder, type II. Cameron has a new special, Four Pills, that’s part stand-up comedy and part reflection on the circumstances that led to this discovery as well as thoughts on what life as a treated person for bipolar will mean going forward. Cameron Esposito joins

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00:37:41

The Thorny Issue of Airline Pilots and Mental Illness

Depresh Mode with John Moe ·

2025/04/07

Statistics say that 23% of Americans are currently living with some form of mental illness. For most people, that calls for reaching out for help and receiving treatment and advice on management. But if you’re an FAA-approved airline pilot, disclosing that you have something like a depressive disorder or an anxiety problem can mean a temporary pause or permanent end to your entire career. Of course, having a mental illness, not disclosing or getting treatment, and flying anyway presents a variety of

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00:48:36

Hanif Abdurraqib on Cultivating a Support System,...

Depresh Mode with John Moe ·

2025/03/31

Hanif Abdurraqib is a MacArthur Fellow, accomplished poet, and critically lauded author of numerous books, including There’s Always This Year: On Basketball and Ascension, which is now out in paperback. He’s also a person who deals with major depressive disorder and numerous anxiety disorders. In a revealing, positive, and practical interview, Hanif talks about the numerous ways he cares for his mental health issues by both taking care of himself and building a strong community of other people

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00:20:08

Checking in With Friends: Open Mike Eagle

Depresh Mode with John Moe ·

2025/03/26

Things are scary in this country these days for a lot of people. There is turmoil in the government, shakiness in the economy, and a deep divide over what America even means anymore. In times of upheaval, it’s a good idea to reach out to friends, see how they’re holding up, help carry their burdens and sorrows, and see what wise advice they can share about perseverance. We do this on our show from time to time. In this mini-episode, we check in on a good friend of the show Open Mike Eagle. He’s a

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00:06:07

Welcome, New Listeners

Depresh Mode with John Moe ·

2025/03/25

We’ve been seeing an influx of new listeners recently. It’s very exciting. Thank you for that and we’re delighted that you’ve joined us. So we thought we’d take a moment and explain what the show is all about and who it’s for. Spoiler alert: it’s for everyone, including you, regardless of your mental health history.It's the final week of the 2025 Max Fun Drive! Check out the fun thank you gifts and become a member of Max Fun!Check out our I’m Glad You’re Here and Depresh Mode merchandise at the

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01:03:02

Jim James of My Morning Jacket on Depression, EMDR,...

Depresh Mode with John Moe ·

2025/03/24

“I’m very kind to Jim, I’m trying to take good care of Jim, I’m trying to love Jim,” says musician Jim James of the band My Morning Jacket. The kindness he’s showing Jim, himself, is a relatively new thing, he says, after a long time spent kind of beating up on the guy. As My Morning Jacket releases its new album, is, Jim reflects back on issues such as a need for validation through achievement, alcoholism, and depression. And he shares what he’s learned through intense therapy, meditation, EMDR,

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00:05:32

BONUS CONTENT PREVIEW: Depresh Mode: The Game Show

Depresh Mode with John Moe ·

2025/03/20

In this bonus content edition of Depresh Mode, We’re joined by some Maximum Fun all-stars for some very light-hearted and delightfully competitive games that are as informative as they are silly. Our competitors:Justin McElroy of My Brother, My Brother, and Me, Adventure Zone, and SawbonesHal Lublin of Tights & Fights and We Got ThisLaura Swisher, senior producer overseeing about a million Max Fun podcastsWho will win the game Antidepressant, Pokemon, or State Fair Food? Who will emerge victorious

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01:19:17

John Moe helps kick off MFD Spring Break

Depresh Mode with John Moe ·

2025/03/17

It’s not MaxFunDrive without a wild kickoff spectacular! Former real-life VJ and host of MTV's Spring Break 1999, Dave Holmes, takes your favorite MaxFun hosts through some wacky ‘90s- and Spring Break-themed mini games!!Featuring: Dave Holmes, Jeremy Bent, Oscar Montoya, Dimitry Pompée, Tom Lum, Ellen Weatherford, Alex Schmidt, Brenda Snell, Drea Clark, Alonso Duralde, Dan McCoy, Jordan Morris, Manolo Moreno, Ella Hubber, Caroline Roper, Ella McLeod, John-Luke Roberts, Justin McElroy, Clint

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00:54:07

J. Kenji Lopez-Alt on Food, Booze, Weed, Anxiety,...

Depresh Mode with John Moe ·

2025/03/17

The alcohol, says J. Kenji Lopez-Alt, came about in young adulthood, when it solved persistent social anxiety and made him the life of the party. As Kenji found tremendous success in food writing and restaurateuring, he found that he couldn’t really make it through the day without downing between two and five drinks. This wasn’t hard to pull off in the food business, surrounded by booze and a culture that heartily encouraged its consumption. Kenji found that, as is so often the case with mental

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00:50:32

Checking in With Friends During Scary Times: Paul F....

Depresh Mode with John Moe ·

2025/03/10

Maybe you’re one of those people who dreads even looking at the news these days, with stories of layoffs, tariffs, upheaval in foreign policy, and a lack of knowledge as to where this is all going and what it might mean for the future of America and the world. It’s a tumultuous time. When things are chaotic, it can be good to check in with one’s friends and that’s what Depresh Mode does this week. We have conversations of commiseration, of humor, and of hope with comedian and actor Paul F. Tompkins,

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00:48:32

Heavy Substance Use, Heavy Depression, and Heavy...

Depresh Mode with John Moe ·

2025/03/03

Lamb of God is a very popular heavy metal band with Grammy nominations, gold records, and a huge headbanging following. Randy Blythe, front man for the band and author of a new book, Just Beyond the Light, is in recovery from drugs and alcohol and tells stories of finding sobriety, including how it was pretty easy to stay sober while on an Australian vacation surrounded by koalas but a lot harder once he returned to the States and the old patterns and routines of his life. Randy also talks about

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00:47:25

Microdosing with James Fadiman and Jordan Gruber

Depresh Mode with John Moe ·

2025/02/24

Microdosing involves taking very small amounts of psychedelic substances such as LSD or psilocybin, maybe seven to twelve percent of a regular dose. It’s not enough to “trip out” but enough, proponents say, to yield very positive results, especially in terms of treating depression that hasn’t responded well to other methods. The catalog of extensive clinical, scientific trials about the practice of microdosing is pretty limited but James Fadiman and Jordan Gruber have collected what scientific

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