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PODCAST

Let"s Talk Micro

Clinical microbiology explained in simple terms, suitable for students and microbiologists alike. We discuss organisms, reactions, infectious diseases, and more. Hosted by Luis Plaza, a Medical Laboratory Scientist and microbiologist, who also shares his experiences in the field.

science life sciences

All Episodes

18:24

TBT: LPC-233: An LpxC inhibitor

Let"s Talk Micro ·

2024/08/01

Originally published in November 30 2023, in this episode, Dr. Pei Zhou from the Duke University School of Medicine joins the podcast and talks to Luis about LPC-233. This is a compound that shows bactericidal activity against some gram-negative rods. LPC-233 is an LpxC inhibitor. What is LpxC? How does LPC-233 works? What are some challenges of developing LpxC inhibitors? Tune in to find out.Link to article: https://doi.org/10.1126/scitranslmed.adf5668Questions? Feedback? Send those to

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21:27

TBT: Fabimycin: an antibiotic candidate

Let"s Talk Micro ·

2024/07/25

Originally published on October 13, 2022, in this episode Luis talks to Dr. Paul Hergenrother from the University of Illinois. Dr. Hergenrother talks about Fabimycin, an antibiotic candidate for gram negative bacteria. What is Fabimycin's mechanism of action? To which bacteria does it show activity against? Any intrinsic resistance? Tune in to find out.Link to article: https://pubs.acs.org/doi/10.1021/acscentsci.2c00598Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the

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33:27

151: Ace the Boards: Microbiology

Let"s Talk Micro ·

2024/07/18

A great way to end season 3! In this episode Dr. Cullen Lilley talks to Luis about his textbook : A Concise Review of Clinical Microbiology . Dr. Lilley is a pathology resident, with a Microbiology background, and a Let's Talk Micro listener! Tune in to learn about what is in this microbiology textbook, what is Ace my Path, and more. Link to Ace My Path: https://www.acemypath.comLink to textbook: https://a.co/d/gGDiZ8ZQuestions? Feedback? Send those to letstalkmicro@outlook.comWant to support the

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38:24

150: Sterile body fluids and Multiplex PCR

Let"s Talk Micro ·

2024/07/11

In the laboratory we routinely use molecular testing to identify organisms in blood cultures. We also incubate body fluids in blood culture bottles. What if we could use those same tests to identify organisms from body fluids? In this episode Christina Cox and Joel Mortensen join the podcast to talk about this. They performed a study where they used the cobas® eplex system (GenMark) to identify organisms recovered from sterile body fluid cultures. Tune in to hear about the results and the

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41:39

TBT: Respiratory cultures

Let"s Talk Micro ·

2024/07/04

Throwback Thurdsday! This week shows an episode originally released in 2022 where Luis talks to Andrea Prinzi about respiratory cultures. What are the types of respiratory cultures? What are the pathogens? What is the significance of yeast in respiratory cultures? Sputum rejection? Tune in to this episode to learn more about these cultures.Link to article about sputum rejection that Dr. Prinzi mentions in the episode: https://journals.asm.org/doi/pdf/10.1128/jcm.16.4.627-631.1982Questions? Feedback

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38:20

149: Talking Microbiome

Let"s Talk Micro ·

2024/06/27

In this episode Luis is joined by Dr. Crystal Icenhour to talk about the microbiome, more specifically, the human microbiome. What organisms typically make up the microbiome? Do they change between areas of the body? What are some applications for the microbiome? Tune in for another great episode. Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi: https://ko-fi.com/letstalkmicro

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29:44

148: Bonus: Live from ASM Microbe 2024

Let"s Talk Micro ·

2024/06/25

ASM Microbe 2024 took place in Atlanta Georgia from June 13-17. Check out this bonus episode where Luis discusses his two events, favorite posters, and more. Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi: https://ko-fi.com/letstalkmicro

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75:56

147: Research in Medical Laboratory Science: moose,...

Let"s Talk Micro ·

2024/06/20

Research in MLS? In this episode Grace Leu-Burke, director of the Medical Laboratory Sciences (MLS) program at the University of Alaska in Anchorage, returns to the podcast. She talks to Luis about the research program the MLS students are involved in. They culture scat from moose, bears, and geese, perform identification and susceptibility testing, and more. What kind of antimicrobial resistance is found in this sample population? Tune in to learn more about this research. Link to JAM meeting

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25:05

146: Urinary Tract Infections (UTIs)

Let"s Talk Micro ·

2024/06/13

In this episode Luis talks to Dr. Madeline Barron about urinary tract infections (UTIs). Clinical Microbiologists work closely with urine cultures and recover many organisms and perform susceptibility testing. However some questions come to mind. What causes a UTI ? What organisms are typically seen in UTIs? Any treatment options other than antimicrobials? Tune in to find out.Madeline Barron's article: https://asm.org/articles/2024/may/why-urinary-tract-infections-uti-recurQuestions? Feedback? Send

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41:42

145: Talking AMR: Polymyxins (lipopeptides)

Let"s Talk Micro ·

2024/06/06

Luis and Andrea are back to talk AMR! This time they are joined by Dr. Alyssa Walker to go over polymyxins . As usual they go over important questions such as mechanism of action, intrinsic resistance, applying the interpretation of one drug to another, and more. What media used in the laboratory has colistin in it? Don't miss another great episode. Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a

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42:42

144: Serie en Español: Tinción de Gram

Let"s Talk Micro ·

2024/06/04

Regresa la serie en Español. Luis y Maridaliz discuten la tinción de gram. Cómo se prepara la laminilla? Cúales son los reactivos y el proceso? Qué diferencia hay entre bacterias gran-positiva y gram-negativa? Sintonizen a este episodio para aprender sobre una de las pruebas mas importantes en Microbiología Clínica. Preguntas? Comentarios? Envíen un correo electrónico a letstalkmicro@outlook.comDesean apoyar al podcast? Pueden hacerlo de la siguiente forma:Venmo: https://venmo.com/u/letstalkmicroBuy

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66:28

143: Navigating your Path

Let"s Talk Micro ·

2024/05/30

Have you been in a job or career that you feel is not a good fit for you? Perhaps you want to try something different but do not know how to get there? Sometimes you might be dreading going to work or just feel unhappy. In this episode Luis talks to Dr. Duane Newton. Duane is a microbiologist with extensive training and at one point in his career he describes feeling "miserable". What did he do to change that? Tune in to this episode to listen to how Duane navigated his path to find himself in a

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77:46

142: UAA MLS : Microbiology and Research

Let"s Talk Micro ·

2024/05/23

In this episode Luis talks to Grace Leu-Burke, Program Director and professor at the University of Alaska in Anchorage (UAA) Medical Laboratory Sciences Program. She joins the podcast to talk about her career and talks about the MLS program at UAA. She goes over the Microbiology curriculum, the importance of biochemical testing, and more. She also talks about the research that her students are conducting involving moose and stool samples.Link to UAA MLS program:

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37:25

141: AR Isolate Bank

Let"s Talk Micro ·

2024/05/16

As a microbiologist, you might have worked on a project or validation that involved organisms from the AR Isolate Bank. You might have asked where they came from and you were told that they were obtained from the Center for Disease Control and Prevention (CDC). What is the Antimicrobial Resistance Isolate Bank (AR Bank)? What organisms are part of this bank? What are they used for? In this episode Luis is joined by two guests from the CDC to answer these questions and more.Links to the AR Isolate

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51:19

140: Talking AMR: Tetracyclines

Let"s Talk Micro ·

2024/05/09

The next episode of the AMR series is here! Luis and Andrea are joined by Dr. Brandon Hill to talk about the Tetracyclines. What is the mechanism of action of this antimicrobial group? What drugs are part of it? Is there any intrinsic resistance? Tune in for another great episode where we "break down" antimicrobials. Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi:

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25:33

139: Bacillus: morphology and media

Let"s Talk Micro ·

2024/05/02

Originally released as episode 76, in this episode Luis continues going over Bacillus. Now that we know its groups and what diseases they are implicated on, it's time to talk about media and morphology. What do the colonies look like? What is MYP agar? PEMBA? Tune in to find out.Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi: https://ko-fi.com/letstalkmicro

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25:35

138: Bacillus species

Let"s Talk Micro ·

2024/04/25

Originally released as episode 75, in this episode Luis talks about Bacillus and related genera. What are the species that are part of this genus? Which species cause food poisoning? What about endophthalmitis? What are spores? Tune in to find out.Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo: https://venmo.com/u/letstalkmicroBuy me a Ko-fi: https://ko-fi.com/letstalkmicro

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24:41

137: Corynebacterium diphtheriae: media and more

Let"s Talk Micro ·

2024/04/18

In this episode Luis continues going over Corynebacterium. In the last episode he mentioned some media that is used to isolate Corynebacterium diphtheriae. Have you heard of cystine tellurite agar? How about Tinsdale agar? What type of testing is there for the diphtheria toxin?What test systems can identify C. diphtheriae? Tune in to learn more about this organism and how this media works. Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the podcast? Here's how:Venmo:

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25:41

136: Corynebacterium

Let"s Talk Micro ·

2024/04/11

Back to the gram-positive rods! This week Luis goes back to gram-positive rods: Corynebacterium this time. The episode starts with an overview: gram stain, biochemicals, morphology, and species. What do you know about Corynebacterium diphtheriae? Does it always cause diphtheria? What is a pseudomembrane? Tune in and download this episode to learn about this genus that has some species commonly seen in the laboratory.Questions? Feedback? Send those to letstalkmicro@outlook.comWant to support the

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55:40

135: Talking ID Stewardship, learning antibiotics,...

Let"s Talk Micro ·

2024/04/04

What is antimicrobial stewardship ? What is a hospital antibiogram? In this episode Dr. Timothy Gauthier joins the podcast and talks to Luis about antimicrobial stewardship. Dr. Gauthier is a pharmacist and creator of the IDstewardship.com and Learnantibiotics.com websites. He is also the author of a book titled Learn Antibiotics. Luis asks him about what antibiotics are used to treat certain organisms. Don't miss this great episode.Timothy Gauthier's information:X:

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237 results

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