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PODCAST

Metabolism Made Easy

A J Ghalayini, Ph.D.

This podcast describes selected biochemistry content that could be useful to premedical/medical students. Similar content (podcasts and videos) is available at: https://medbiochem.org/ or check out my YouTube channel: Metabolism Made Easy These podcasts and videos cover selected topics in medical biochemistry. A J Ghalayini, Ph.D. Bio for Dr. Ghalayini: Dr. Ghalayini received his Ph.D. in Biochemistry from the University of Houston, Houston, Texas. He has over 3 decades of experience in

education courses

All Episodes

00:02:43

The Brain Loves Glucose

Metabolism Made Easy ·

2024/01/19

With the exception of ketone bodies, the brain is entirely dependent on glucose as an energy source under most circumstances. Glucose is oxidized all the way to CO2 by the brain, producing up to 38 ATPs. This catabolism is dependent on oxygen, which is used to convert the energy in NADH and FADH2 to ATP through the Electron Transport Chain and Oxidative Phosphorylation. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:34

DIETARY TRIACYLGLYCEROL (Fat): Digestion, Absorption...

Metabolism Made Easy ·

2024/01/04

This podcast covers the digestion of the major dietary fat, triacylglycerol, including digestion uptake into intestinal mucosa, delivery through the bloodstream, uptake and storage of fatty acids from chylomicrons in the bloodstream. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:06

Transport of Ammonia by Glutamine

Metabolism Made Easy ·

2023/12/14

This podcast describes the transport of ammonia produced in peripheral tissues by incorporating it into glutamine through glutamine synthase. Glutamine is transported in the bloodstream to either the liver or kidney for further metabolism. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:08:31

Metabolism During Fasting

Metabolism Made Easy ·

2023/11/07

This podcast provides an overview of metabolic changes associated with fasting, including key metabolic changes in the liver and adipose tissue. The liver will increase its output of glucose and ketone bodies, while adipose tissue will provide fatty acids to the bloodstream for other peripheral tissues to use during fasting. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:14:52

METABOLISM: A Biochemical Summary

Metabolism Made Easy ·

2023/09/14

This podcast summarizes the key biochemical components of metabolism, including: 1. definition; 2. cellular location; 3. the major catabolic pathways; 4. the 3 stages of catabolism; 5. the 12 major metabolic uses of glucose, fatty acids and amino acids; 6. the energy output of catabolism of glucose, fatty acids, and ketone bodies. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:09:15

Enzyme Regulation

Metabolism Made Easy ·

2023/09/05

This podcast covers 5 distinct enzyme regulatory mechanisms and their effects on enzyme structure and activity. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:11:12

The Urea cycle : Key Features and Enzymes

Metabolism Made Easy ·

2023/07/27

This podcast covers the function and the location of the urea cycle, including some key features and the sequence of the enzymes as well as their location. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:04:11

TRANSAMINASES: Amino acid degradation

Metabolism Made Easy ·

2023/06/28

This podcast covers the role of transaminases the initial step in the degradation of amino acids. This includes the role of glutamate dehydrogenase in producing ammonia. The ammonia and aspartate produced are then able to enter the urea cycle in the liver. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:05:40

Adipocytes, lipolysis, and energy reserves

Metabolism Made Easy ·

2023/06/16

This podcast covers the role of adipocytes in energy storage and their role in initiating lypolysis of stored triacylglycerols to provide various tissues with fatty acids as a energy source. The role of fatty acid Beta-oxidation in providing energy from both dietary or stored triacylglycerols is also covered. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:00:58

The Cori Cycle

Metabolism Made Easy ·

2023/05/24

This podcast covers the details of the conversion of lactate produced during exercise to glucose in the liver and ultimately releasing it to the bloodstream. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:02:09

Regulation of Acetyl CoA Carboxylase

Metabolism Made Easy ·

2023/05/02

This pocast covers the regulation of the Rate-limiting enzyme in fatty acid synthesis, Acetyl CoA Carboxylase allosterically, and by covalent modification. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:05:26

Regulation of Cholesterol Biosynthesis

Metabolism Made Easy ·

2023/04/24

This podcast covers the regulation of HMG CoA Reductase by hormones, covalent modification, cytoplasmic cholesterol, and statins. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:02:04

What is Metabolism?

Metabolism Made Easy ·

2023/04/10

This podcast defines metabolism and its two distinct components: anabolism and catabolism. The major compartments involved in both are also covered. If you like this podcast, feel free to donate to the podcast. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:03:04

Dietary Components: 12 distinct uses

Metabolism Made Easy ·

2023/04/03

This podcast covers the distinct uses of glucose, fatty acids, and amino acids and their unique roles in metabolism. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:06:10

What happens when we fast: The plasma sources of...

Metabolism Made Easy ·

2023/03/20

This podcast covers the key role of the liver and adipose tissue in providing energy sources to the plasma during fasting. The liver is the provider of glucose and fatty acids, while adipose tissue provides fatty acids to the bloodstream. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:04:18

What a ketogenic diet teaches us about metabolism?

Metabolism Made Easy ·

2023/03/10

While following a ketogenic diet, maintenance of plasma glucose is essential for several tissues. The amino acids derived from dietary proteins will provide the carbon skeletons for glucose synthesis by the liver, while the triacylglycerols from dietary fat will provide the energy for various tissues through Beta-oxidation of fatty acids. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:03:09

3 GPCRs: 4 second messengers

Metabolism Made Easy ·

2023/03/06

This podcast covers the production of cAMP by activation of either the beta-adrenergic receptor or the glucagon receptor as well as the activation of the alpha1-adrenergic by epinephrine to produce IP3, DG and calcium. --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

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00:02:59

The 3 Stages of Catabolism

Metabolism Made Easy ·

2023/02/22

This podcast covers the 3 stages of catabolism from the intestinal lumen to inside the cell. The energy output is mostly produced in the mitochondrial catabolic pathways. Similar content is available at: https://medbiochem.org/ --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:04:02

Major Metabolic Pathways for Carbohydrates and Fat

Metabolism Made Easy ·

2023/02/09

This podcast covers the major pathways for catabolism of glucose and fatty acids, including the ATP output from their complete degradation to CO2. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

00:02:19

NSAIDS, Cortisol and Inflammation

Metabolism Made Easy ·

2023/01/18

This podcast covers the target enzymes of NSAIDS and cortisol and their respective effects on inflammation. This biochemistry content may be useful to premedical and medical students. Similar content is available at: MEDBIOCHEM.ORG --- Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message

en

213 results

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