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PODCAST

NEJM This Week

Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.

health & fitness medicine

All Episodes

31:07

NEJM This Week — May 9, 2024

NEJM This Week ·

2024/05/08

Featuring articles on gene editing in severe sickle cell disease and in transfusion-dependent β-thalassemia, thrombectomy for stroke with a large infarct, and recombinant ADAMTS13 in life-threatening immune thrombotic thrombocytopenic purpura; a review article on taste physiology; a case report of a woman with back pain, leg stiffness, and falls; and Perspective articles on the public good on the docket, on reengineering addiction, on welcoming the era of gene editing in medicine, and on all’s fair

en-US

25:57

NEJM This Week — May 2, 2024

NEJM This Week ·

2024/05/01

Featuring articles on a monoclonal antibody to prevent malaria, apolipoprotein A1 and outcomes after myocardial infarction, transcatheter or surgical treatment of aortic-valve stenosis, and recombinant ADAMTS13 in congenital thrombotic thrombocytopenic purpura; a review article on cryptococcal disease in diverse hosts; a Clinical Problem-Solving on the meat of the matter; and a Perspective on Journal voices in the civil rights era.

en-US

31:32

NEJM This Week — April 25, 2024

NEJM This Week ·

2024/04/24

Featuring articles on empagliflozin after acute myocardial infarction, CD7 CAR T cells with allogeneic stem-cell transplantation, FFR-guided complete revascularization for STEMI, and nutrition for moderate-to-late preterm infants; a review article on age-related hearing loss; a case report of a man with leg weakness; and Perspective articles on hospital consolidation and physician unionization, on the myth of the free market for pharmaceuticals, and on going beyond code status.

en-US

33:00

NEJM This Week — April 18, 2024

NEJM This Week ·

2024/04/17

Featuring articles on adjuvant pembrolizumab after surgery in renal-cell carcinoma, beta-blockers after MI with preserved ejection fraction, a microaxial flow pump for STEMI and cardiogenic shock, and semaglutide in patients with heart failure and diabetes; a review article on retinoblastoma; a case report of a woman with confusion, aphasia, and abnormal head imaging; and Perspectives on expanding applications of clinical genetic testing, on twenty-five years after Columbine, on advocating for a

en-US

36:44

NEJM This Week — April 11, 2024

NEJM This Week ·

2024/04/10

Featuring articles on alectinib in ALK-positive lung cancer, minimally invasive removal of cerebral hematomas, and CAR T-cell–mediated responses in recurrent glioblastoma; a review article on energy and macronutrients across the life span; a case report of a woman with falls and cognitive decline; a Medicine and Society on money as medicine; and Perspectives on back to the future in Alabama, on the end of B/Yamagata influenza transmission, and on the plight of DEI leaders.

en-US

28:55

NEJM This Week — April 4, 2024

NEJM This Week ·

2024/04/03

Featuring articles on omitting axillary dissection in breast cancer with sentinel-node metastasis, a trial of lixisenatide in early Parkinson’s disease, nirmatrelvir–ritonavir in outpatients with Covid-19, and hospitalization for chronic kidney disease; a review article on the prevention of cardiovascular disease in type 1 diabetes; a case report of a woman with hyperglycemia refractory to insulin; and a Perspective article on Nazism and the Journal.

en-US

30:56

NEJM This Week — March 21, 2024

NEJM This Week ·

2024/03/20

Featuring articles on autism and prenatal exposure to antiseizure medication, ribociclib plus endocrine therapy in early breast cancer, gene therapy for giant axonal neuropathy, and anti–interleukin-23 in immunodeficiency; a review article on wearable digital health technologies in clinical care; a case report of a man with a fall; and Perspective articles on physicians, spirituality, and compassionate care; on the risks posed by immediate release of test results to patients; and on what one author

en-US

33:12

NEJM This Week — March 14, 2024

NEJM This Week ·

2024/03/13

Featuring articles on a blood-based test for colorectal cancer screening, a multitarget stool DNA test for colorectal cancer, iptacopan for paroxysmal nocturnal hemoglobinuria, and preterm birth and other outcomes of maternal RSV vaccination; a review article on cerebral cavernous malformations; a case report of a man with cardiac arrest, cardiogenic shock, and hypoxemia; and Perspective articles on vertical integration and American medicine; on aspirin, preeclampsia, and racism; and on a shift in

en-US

30:35

NEJM This Week — March 7, 2024

NEJM This Week ·

2024/03/06

Featuring articles on an antibody–drug conjugate in untreated urothelial cancer, omalizumab for multiple food allergies, microplastics and nanoplastics in carotid plaque, and benralizumab or mepolizumab for eosinophilic granulomatosis with polyangiitis; a review article on the health effects of endocrine-disrupting chemicals; a Clinical Problem-Solving on peeling and plummeting; a Medicine and Society on beyond moral injury; and a Perspective article on eugenics in the Journal.

en-US

31:39

NEJM This Week — February 29, 2024

NEJM This Week ·

2024/02/28

Featuring articles on a trial of seladelpar in primary biliary cholangitis, a trial of elafibranor in primary biliary cholangitis, cognition and memory after Covid-19, and simple versus radical hysterectomy in women with low-risk cervical cancer; a review article on cardiac rehabilitation; a case report of a woman with alternating sixth cranial nerve palsy; and a Perspective article on practicing medicine in the culture wars. We also describe a new cases series on efforts toward equity in health

en-US

34:55

NEJM This Week — February 22, 2024

NEJM This Week ·

2024/02/21

Featuring articles on CD19 CAR T-cell therapy in autoimmune disease, tenecteplase for stroke at 4.5 to 24 hours, biomarker changes in years before Alzheimer’s disease, and a hepcidin mimetic in polycythemia vera; a review article on wearable digital health technologies for epilepsy; a case report of a man with fatigue and night sweats; and Perspective articles on direct-to-consumer platforms for antiobesity medications, on childhood obesity prevention, and on what is a mentor.

en-US

32:54

NEJM This Week — February 15, 2024

NEJM This Week ·

2024/02/14

Featuring articles on frexalimab in multiple sclerosis, e-cigarettes for smoking cessation, cefepime–taniborbactam for complicated UTI, and the treatment of Wolman’s disease in an infant; review articles on treatment-resistant depression in older adults and on Behçet’s syndrome; a case report of a man with fevers; and Perspective articles on ethical issues in safety-net health systems, on secondary cancers after CAR T-cell therapy, and on being worried about white-cell counts.

en-US

38:12

NEJM This Week — February 8, 2024

NEJM This Week ·

2024/02/07

Featuring articles on a phase 3 trial of resmetirom in NASH with liver fibrosis, an interleukin-23–receptor antagonist for plaque psoriasis, the neurovascular complications of F. solani meningitis, and on ocular gene therapy; a review article on coccidioidomycosis and histoplasmosis; a case report of a man with fever and headache after international travel; Medicine and Society articles on a physician attack on the FDA and on being well while doing well; and Perspective articles on the risks of

en-US

30:07

NEJM This Week — February 1, 2024

NEJM This Week ·

2024/01/31

Featuring articles on an attenuated tetravalent dengue vaccine, skin antisepsis before fracture surgery, N-acetyl-l-leucine in Niemann–Pick Disease type C, in vivo CRISPR-Cas9 treatment for hereditary angioedema, and on seeing medicine more as a job than a calling; a review article on cardiac implantable electronic devices; a Clinical Problem-Solving on flipping the switch; and a Perspective article on explaining health inequities.

en-US

32:12

NEJM This Week — January 25, 2024

NEJM This Week ·

2024/01/24

Featuring articles on daratumumab in myeloma therapy, the early treatment of patent ductus arteriosus with ibuprofen, measurable residual disease in chronic lymphocytic leukemia, hospital prices for physician-administered drugs, and on Asian Americans and racial justice in medicine; a review article on wearable technologies in cardiovascular medicine; a case report of an infant with inconsolable crying and weakness; and Perspective articles on minding the gap, on transforming population health, and

en-US

34:46

NEJM This Week — January 18, 2024

NEJM This Week ·

2024/01/17

Featuring articles on testosterone treatment and fractures in men, long-term resynchronization–defibrillation therapy for heart failure, azithromycin to prevent infant mortality in Burkina Faso, oral simnotrelvir for adult patients with Covid-19, understanding liability risk from health care AI tools, and the rise of house staff unions; a review article on syphilis during pregnancy and congenital syphilis; a case report of a woman with melanoma and fever; and Perspective articles on responding to

en-US

34:29

NEJM This Week — January 11, 2024

NEJM This Week ·

2024/01/10

Featuring articles on apixaban for stroke prevention in subclinical atrial fibrillation, repotrectinib for ROS1 fusion–positive lung cancer, acoramidis in transthyretin amyloid cardiomyopathy, low-dose calcium supplementation in pregnancy, and the financialization of health in the United States; a review article on peripartum cardiomyopathy; a case report of a woman with bleeding after a snakebite; and Perspective articles on the overdose crisis among U.S. adolescents, on accuracy and equity in

en-US

29:02

NEJM This Week — January 4, 2024

NEJM This Week ·

2024/01/03

Featuring articles on a drug-eluting scaffold for infrapopliteal disease, a phase 2 trial of sibeprenlimab in IgA nephropathy, liquefied petroleum gas cooking and the effects on severe infant pneumonia and on stunting in infants; a review article on communicating about serious illness and end of life; a Clinical Problem-Solving describing a swell diagnosis; and Perspective articles on the Journal’s historical “Indian Problem”.

en-US

34:40

NEJM This Week — December 28, 2023

NEJM This Week ·

2023/12/27

Featuring articles on dual or single antiplatelet treatment up to 72 hours after stroke, nirsevimab for prevention of RSV hospitalization in infants, sparsentan in focal segmental glomerulosclerosis, transfusion strategy in patients with myocardial infarction and anemia, and the effect of alcohol reduction on cancer incidence; a review article on wearable technology in clinical practice for depressive disorder; a case report of a woman with cough and shortness of breath; and Perspective articles on

en-US

34:21

NEJM This Week — December 21, 2023

NEJM This Week ·

2023/12/20

Featuring articles on percutaneous coronary intervention for stable angina, doxycycline prophylaxis to prevent STIs in women, simvastatin for critically ill patients with Covid-19, and melioidosis in Mississippi; a review article on eye infections; a case report of a woman with chronic diarrhea and skin changes; and Perspective articles on when patients lose decision-making capacity, on silencing the FDA’s voice, and on being hidden behind bars.

en-US

101 results

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