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PODCAST

Clinical Chemistry Podcast

Association for Diagnostics and Laboratory Medicine

This free monthly podcast is offered by Clinical Chemistry. Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today"s clinical laboratory.

science chemistry

All Episodes

06:26

Whats Different about Womens Health?

Clinical Chemistry Podcast ·

2014/01/03

Until recently, much of the research in medical literature used primarily male populations. Slowly we've come to appreciate the importance of studying female populations due to the differences in normal physiology as well as disease pathology between men and women.

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21:02

High-Sensitivity Cardiac Troponin Assays: Isn't It...

Clinical Chemistry Podcast ·

2014/01/03

Women who present with acute coronary events are less frequently to be properly diagnosed and often have worse outcomes than men. Part of the problem may be that women are less apt to manifest increased biomarkers or often receive less aggressive guideline-mandated care. Women also have lower reference values for biomarkers of cardiac injury that are rarely taken into account.

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07:46

Tumor MicroenvironmentReleased Peptides: Could They...

Clinical Chemistry Podcast ·

2014/01/03

The January 2014 issue of Clinical Chemistry is devoted to the area of women's health. It includes a multi-center report on the application of measuring the circulating products of the proteolytic enzyme carboxypeptidase-N for the early detection of breast cancer. Accompanying that paper was an editorial by Eleftherios Diamandis on the tumor microenvironment and if released peptides could form the basis for early diagnosis breast cancer tests.

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18:32

Gestational Diabetes Mellitus

Clinical Chemistry Podcast ·

2013/12/10

Gestational diabetes mellitus is becoming more common as the epidemic of obesity and type 2 diabetes continues. Newly proposed diagnostic criteria will, if adopted universally, further increase the prevalence of this condition.

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10:36

Diagnosing Diabetes Mellitus: Performance of...

Clinical Chemistry Podcast ·

2013/12/03

In making the diagnosis of diabetes, there are several advantages using determinations of hemoglobin A1c rather than glucose measurements. These include the pre-analytics stability of hemoglobin A1c in the sample, a low within-subject biological variation, as well as being free from the dietary restrictions associated with measuring glucose.

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10:05

FullIssueSummary December2013

Clinical Chemistry Podcast ·

2013/12/01

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09:24

Digital Droplet PCR for Rapid Quantification of Donor...

Clinical Chemistry Podcast ·

2013/11/18

Cell free DNA from transplanted organs in the circulation of transplant recipients is a potential biomarker of rejection. But most of these methods entail high costs, long turnaround times and the need for donor DNA.

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06:42

Multiplex Picodroplet Digital PCR to Detect KRAS

Clinical Chemistry Podcast ·

2013/11/11

Multiplex digital PCR can be used for the sensitive detection of circulating tumor DNA with performance unachievable by other current molecular detection approaches.

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08:06

MicroRNA Signature Helps Distinguish Early from Late...

Clinical Chemistry Podcast ·

2013/11/05

The elevation in the concentrations of prostate-specific antigen, or PSA, in blood after prostatectomy is the only available marker from monitoring relapse after surgery. This increase in PSA is sometimes called biochemical failure or biochemical relapse. PSA monitoring, however, cannot predict relapse at the time of surgery.

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10:45

FullIssueSummary November2013

Clinical Chemistry Podcast ·

2013/11/01

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13:22

Bioinformatics: What the Clinical Laboratorian Needs...

Clinical Chemistry Podcast ·

2013/10/29

New diagnostics technologies such as microarrays, next generation, or massively parallel sequencing, are generating an unprecedented amount of data. This requires a sophisticated knowledge of bioinformatics for proper storage, analysis, and mining of these very large data sets.

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13:38

Use of MALDI-TOF for diagnosis of microbial infections

Clinical Chemistry Podcast ·

2013/10/21

The application of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry or MALDI-TOF MS, to microbial identification is revolutionizing clinical microbiology, providing rapid identification with minimal sample preparation and potential cost savings.

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05:42

ClinChem 201310 Rifai

Clinical Chemistry Podcast ·

2013/10/14

And our guest today is Dr. Nader Rifai, Editor-in-Chief of Clinical Chemistry and Chair of the Clinical Chemistry Trainee Council, to announce the launch of a new program from AACC's Clinical Chemistry Trainee Council, the Question Bank. And Dr. Rifai, why was the Question Bank created?

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12:06

False Biomarker Discovery Due to Reactivity of a...

Clinical Chemistry Podcast ·

2013/10/04

The discovery phase of proteomics is critical in the identification of suitable markers for exploration and validation of promising new clinical tests. But can laboratories be certain if what they believe they are measuring is, in fact, what they actually measuring?

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09:25

FullIssueSummary October2013

Clinical Chemistry Podcast ·

2013/10/01

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07:33

Scanning for cancer genomic changes in plasma:...

Clinical Chemistry Podcast ·

2013/09/23

The analysis of circulating cell-free tumor DNA has considerable potential for the detention and monitoring of cancers. Substantial effort has been made to identify cancer associated genetic changes that might be suitable for use as new tumor markers. However, only a few of these genetic markers have been translated into clinical use.

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Automation in the Clinical Microbiology Laboratory

Clinical Chemistry Podcast ·

2013/09/16

The clinical microbiology laboratory is sometimes considered low-tech, particularly when compared to the high degree of automation found in the clinical chemistry laboratory. However, systems are emerging for the clinical microbiology laboratory with the potential to automate almost all areas of testing, including inoculation of primary culture plates, detection of growth on culture media, susceptibility testing, and extraction and detection of nucleic acids from clinical specimens.

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13:16

Automation in the Clinical Microbiology Laboratory

Clinical Chemistry Podcast ·

2013/09/16

The clinical microbiology laboratory is sometimes considered low-tech, particularly when compared to the high degree of automation found in the clinical chemistry laboratory. However, systems are emerging for the clinical microbiology laboratory with the potential to automate almost all areas of testing, including inoculation of primary culture plates, detection of growth on culture media, susceptibility testing, and extraction and detection of nucleic acids from clinical specimens.

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07:02

Point-of-Care and Over-the-Counter Qualitative Human...

Clinical Chemistry Podcast ·

2013/09/09

For many taking a home pregnancy test can be upsetting, particularly if there is not complete confidence in the result. The November 2013 print issue of Clinical Chemistry published a paper from a group led by Dr. Ann Gronowski that reported false-negative results in point-of-care and over-the-counter qualitative hCG devices.

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12:21

Twenty-Eight Grams of Prevention Is Worth a Half...

Clinical Chemistry Podcast ·

2013/09/03

Maintaining long-term stability of analytical procedures is an important responsibility for clinical laboratories. This process typically includes a comparison of current and new reagent lots through paired measurements of patient or control samples, with defined criteria for acceptance and rejection of the new lot.

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1,086 results

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