At the Save Our Sites (SOS) conference, many site owners expressed excitement over finally having a space to openly discuss real challenges—budgets, pricing, contracting, and the isolation of being a site owner. While the intent was mutual support, concerns quickly arose when some attendees began advocating for standardized pricing across sites (e.g., "$200 for an X-ray")—a move that borders on illegal price fixing. Darshan raised red flags, emphasizing that while site collaboration is valuab...

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们要介绍发表在《Trends in pharmacological sciences》(IF:13.9)上的重要综述"The B7-H3 (CD276) pathway: emerging biology and clinical therapeutics"。这项研究揭示了B7-H3作为免疫检查点配体和肿瘤相关抗原的多重功能，不仅参与肿瘤微环境调控，还发现其与肥胖相关的新作用。更令人振奋的是，针对B7-H3的抗体药物偶联物和CAR细胞临床试验已在多种癌症中显示出安全性和有效性。此外，研究者还介绍了TOP CAR细胞、双特异性ADCs等创新疗法，为癌症免疫治疗开辟了新途径。这项研究为理解B7-H3的生物学功能和开发靶向疗法提供了重要见解。

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们要介绍一篇发表在《Trends in pharmacological sciences》(影响因子13.9)上的重要综述——《The B7-H3 (CD276) pathway: emerging biology and clinical therapeutics》。这项研究揭示了B7-H3这一免疫检查点配体在癌症和肥胖中的双重作用，不仅是一种肿瘤相关抗原，还新发现它能调节肥胖。更令人兴奋的是，靶向B7-H3的抗体药物偶联物和CAR细胞疗法已在临床试验中展现出良好的安全性和有效性。这些突破性发现为癌症免疫治疗开辟了新途径，可能改变未来多种癌症的治疗格局。

Vamos hablar sobre los capitulos 10,11 y 12 del libro

科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。最新研究发现，免疫受体SLAMF5在调节多发性硬化症（MS）中的髓系细胞介导的神经炎症中发挥关键作用。研究团队利用实验性自身免疫性脑脊髓炎（EAE）小鼠模型，发现SLAMF5缺乏可减少髓系细胞激活和共刺激分子表达，延缓疾病进展。此外，药物阻断SLAMF5可减缓病情发展，减少髓系细胞激活标志物表达。这项研究为治疗MS等自身免疫性疾病提供了新的治疗靶点，具有重要的临床意义。

Selbstcoaching Online

The recent conviction of a Michigan pharmacist and his brother in a $15 million healthcare fraud scheme highlights the growing crackdown on pharmacy-related fraud. The scheme involved billing for medications that were never dispensed, targeting Medicare, Medicaid, and private insurance. This pattern of fraud is not new, as the Department of Justice (DOJ) recently charged nearly 200 individuals in similar cases amounting to $2.75 billion in fraud claims. Pharmacies, both large and small, are i...

Speakers: Kenzy Aly, Karima Waleed, Omar SolimanExpert: Leena

Speakers: Fayrouz Tamer, Haya Mohamed, Kenzy AlyExpert: Aly

Speakers: Khadijah Ahmed, Omar Soliman, Steven EmadExpert: Farida

欢迎收听科研喵播客，用AI读文献，效率翻倍！立刻访问labcat.com.cn下载吧。今天，我们要探讨的是最新的医学研究进展，关于围手术期神经认知障碍（PNDs）。这项研究揭示了PNDs的分子机制和生物活性分子的最新发现。PNDs是手术后常见并发症，尤其在老年患者中，表现为记忆力减退和认知功能下降。研究聚焦于微胶质细胞激活、细胞因子失衡和NLRP3炎症体介导的细胞焦亡等机制。此外，还讨论了麻醉和手术如何干扰神经递质系统，影响突触可塑性。这项研究为我们提供了预防和治疗PNDs的新方向，包括生物活性化合物和神经保护剂。不要错过这一突破性发现，让我们一起关注老年患者的术后恢复和认知健康。

Here’s an episode that will keep you waiting for the next one. Tune in now!

Here’s an episode that will keep you waiting for the next one. Tune in now!

Here’s an episode that will keep you waiting for the next one. Tune in now!

Here’s an episode that will keep you waiting for the next one. Tune in now!

We’re excited to announce season six of the Looking at Lyme podcast! New conversations with scientists, advocates, experts, and others will bring you interesting and fresh perspectives from across Canada and around the world.The more we learn, the better equipped we’ll be to create positive change. Building Lyme literacy that places the patient first is what our podcast is about in so many ways. To better understand where we’re at in diagnosing, and treating Lyme, and other tick-borne

Send us a text In this Quality Grind Short, we delve into the concept of coachability and its critical role in organizational effectiveness and team success. We explore how individuals and teams can become more open to feedback, shift their behavior, and embrace a mindset geared towards learning and improvement. The episode highlights the importance of creating a culture of 'feed forward' in leadership, which focuses on future success rather than past mistakes. Tune in for actionable tips and...

In this episode of STBYM’s The Monstrefact, Robert discusses the Marvel Comics character Medusa, who can put her long, red locks of hair to serious use…See omnystudio.com/listener for privacy information.

Send us a text The retina is a light-sensitive layer at the back of the eye that converts light into nerve signals, which are then transmitted to the brain via the optic nerve. It's composed of various layers, including photoreceptor cells (rods and cones), bipolar cells, and ganglion cells. The retina allows us to see in low light, perceive color, and see sharp details, particularly in the macula, the central part of the retina.

Pharma is finally catching up to the on-demand world—offering direct-to-patient (DTP) services that promise convenience, faster delivery, and a more personalized experience. Major players like Pfizer, Lilly, and Novo Nordisk are leading the way, cutting out intermediaries like pharmacists, PBMs, and even traditional physicians. But convenience comes at a cost. By removing these safeguards, companies take on massive compliance liabilities. Telehealth prescribing raises serious questions around...