В июне 25 года первый свет увидел новый большой телескоп обсерватории имени Веры Рубин. Но на Земле и в космосе уже есть и другие большие обсерватории и могучие телескопы. Чем же этот такой особенный?

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在Gut(影响因子23.0)上的重要研究"SIRT6 promotes intrahepatic cholangiocarcinoma development by reprogramming glutamine metabolism via enhanced GLUL"。这项突破性发现揭示了SIRT6在肝内胆管癌中的致癌作用，通过增强GLUL促进谷氨酰胺代谢重编程。研究团队证实SIRT6在ICC中高表达，其沉默可显著抑制肿瘤生长并增强化疗敏感性。这一发现不仅阐明了SIRT6-GLUL轴在ICC发展中的关键机制，更为靶向治疗提供了新思路，为改善肝内胆管癌患者预后带来希望。

Alice merits two statues in the park, and the caterpillar gets a make-over!Learn more about your ad choices. Visit megaphone.fm/adchoices

Kluge Kohlmeisen: wie schnell sie lernen, Futter zu stehlen; Hitzetage: wo der Anstieg besonders hoch wirdSendung vom 16.10.2025

Produtores rurais e técnicos da Emater Minas se reuniram Sul de Minas para duas etapas do Circuito Frutificaminas, nas cidades de Itanhandu e Passa Quatro. A ação teve como tema a produção de banana e o uso de caldas alternativas e bioinsumos na fruticultura.

Prof. Anja du Plessis, ‘n waterkenner verbonde aan Unisa, praat oor die stand van Suid-Afrika se water.

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在《Environmental science & technology》(IF: 10.8)上的重要研究"Prenatal Insecticide Exposure and Adverse Birth Outcomes: Evidence for Mediation via Disruptions in Amino Acid and Acylcarnitine Metabolism"。这项针对406对母婴的前瞻性队列研究发现，孕期接触杀虫剂会影响新生儿健康。第三孕期尿液中3-PBA和DEDTP水平与出生体重显著降低相关，而DMTP则与更长的孕周相关。研究首次揭示了杀虫剂暴露通过扰乱新生儿氨基酸和酰基肉碱代谢通路，特别是亚油酰肉碱介导的能量代谢紊乱，导致不良出生结局的机制。这一发现为孕期环境健康干预提供了重要科学依据。

Erkältungen, Grippe, Magen-Darminfektionen: Händewaschen als Prophylaxe; Gleichgewichtstraining: warum Skateboarden auf lange Sicht sogar vor Stürzen schützen kannSendung vom 15.10.2025

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。本期关注发表在Environmental Science & Technology (IF: 10.8)上的重要研究"Prenatal Insecticide Exposure and Adverse Birth Outcomes: Evidence for Mediation via Disruptions in Amino Acid and Acylcarnitine Metabolism"。这项研究发现，孕期接触杀虫剂会影响新生儿健康，特别是通过扰乱氨基酸和酰基肉碱代谢途径。研究显示，第三孕期暴露于特定杀虫剂(3-PBA和DEDTP)与新生儿出生体重显著降低相关，而另一种杀虫剂DMTP则与更长的孕周相关。更重要的是，研究者发现C18:2酰基肉碱介导了杀虫剂暴露与低出生体重之间的关联，这为理解环境毒素如何影响胎儿发育提供了新视角，也为预防不良出生结局提供了潜在靶点。

Analogastronauten, ASCINA-Preise, Gorillaweibchen - Sendung vom 14.10.2025

Trail reporter Phil says it’s shaping up to be another great Four Corners weekend for mountain bikers and hikers, with cool temperatures, clear skies, and plenty of color still hanging on in the cottonwoods — plus a new local event for riders in Dolores.

🎧 Day 5 — Love as a DeclarationTheme: Werner Erhard — Responsibility and LoveQuote:“Love is a declaration, not a feeling.”— Werner Erhard🌿 OverviewToday’s rhythm turns love from something passive into something powerful. Werner Erhard reframed love not as emotion, but as responsibility — a conscious declaration of how we choose to show up in the world. Love, in this sense, isn’t reaction or romance; it’s rebellion — the decision to create connection even when the world gives us every reason not

科研喵使用ai读文献，祝你效率百倍，访问labcat.com.cn下载。今天我们关注发表在《Comprehensive Reviews in Food Science and Food Safety》(IF: 12.0)上的重要综述"Gut Microbiota and Lipid Metabolism: Impacts on Lamb Flavor Precursors"。这项突破性研究揭示了羊的独特风味如何源自肠道微生物群与脂质代谢的复杂相互作用。研究发现，脂肪酸、氨基酸等风味前体物质通过微生物氢化、脂肪酸合成等关键过程形成，这些过程共同塑造了羊肉的风味特征。这一发现为通过调控微生物群落和代谢过程来改善羊肉风味提供了科学依据，也将革新羊肉生产加工技术。未来研究将进一步探索如何利用这些微生物和代谢途径提升羊肉品质，为肉类食品行业带来新的发展方向。

In southeast Asia, religious traditions have long saved animals from extinction.Learn more about your ad choices. Visit megaphone.fm/adchoices

Überlebenstraining: Vorbereitung für Astronautin; Nacktmulle: Wie sie zusammenleben - Sendung vom 13.10.2025

O que desafia os produtores rurais em termos de segurança? Como insumos, grãos, rebanhos e cadeias produtivas podem estar seguros? E o que a Polícia Militar tem a ver com tudo isso?Foi para esclarecer essas e outras questões que a P M de Minas Gerais e o Sistema Faemg Senar realizaram nesta semana o primeiro Seminário Segurança no Campo. O evento foi em Belo Horizonte e contou com cerca de 300 policiais militares. Mas a programação também foi transmitida ao vivo para unidades da corporação