Faculty: Komal Jhaveri, MD, FACP Faculty: Kevin Kalinsky MD, MS The PI3K-AKT-mTOR pathway is a crucial signaling network dysregulated in many cancers, promoting cell survival, growth, and proliferation, and often implicated in resistance to cancer therapies. Inhibition of this pathway by PI3K inhibitors disrupts a complex network of cellular processes that contribute to breast cancer, markedly reducing cell proliferation, promoting apoptosis, inhibiting angiogenesis, and ultimately

Faculty: Komal Jhaveri, MD, FACP Faculty: Kevin Kalinsky MD, MS The PI3K-AKT-mTOR pathway is a crucial signaling network dysregulated in many cancers, promoting cell survival, growth, and proliferation, and often implicated in resistance to cancer therapies. Inhibition of this pathway by PI3K inhibitors disrupts a complex network of cellular processes that contribute to breast cancer, markedly reducing cell proliferation, promoting apoptosis, inhibiting angiogenesis, and ultimately

Camilla Rosan talks about what's needed in perinatal mental health services, and tells us about the trial she just led on Circle of Security-Parenting (COS-P).

Jim Sinner discusses the newly-launched Swap One climate initiative – origin of the idea – how it works – the sort of climate and transport benefits it might bring - how to get involved www.swapone.nz https://climatemattersnz.substack.com/ https://www.resilienz.co.nz/climate-matters

The illegal trade in rare insects is booming across Africa, Asia and Latin America. Exotic ants, spiders and beetles are collected and sold as pets. Some species are worth a fortune on the global black market. But scientists are raising alarm bells, as many of these insects are vital to local ecosystems. Our France 2 colleagues report.

Host: Peter Buch, MD, FACG, AGAF, FACP Guest: Alexa Weingarden, MD PhD Probiotic use in gastroenterology remains a complex and evolving topic, shaped by variable evidence and growing patient demand. Dr. Peter Buch sits down with Dr. Alexa Weingarden to review current data, discuss distinctions between probiotic-related therapies, and explore the clinical utility of microbiome testing. Dr. Weingarden is an Assistant Professor of Gastroenterology, Hepatology, and Nutrition at

You've got questions, I've got answers Music 'Hundred Times Over' by Private Joker

Dr. Barry Dworkin opens the phone lines and reads your medical questions. But first, a discussion on how to properly tackle Ottawa's doctor crisis.

See how highly sensitive somatic detection of classic tumor reference samples is made possible through the Twist Oncology - DNA CGP Panel™ combined with downstream analysis using QIAGEN® CLC Genomics Workbench.What is the Twist Oncology - DNA CGP Panel?It is a panel from Twist Biosciences® that is designed for the comprehensive genomic profiling (CGP) of solid tumors to find pathogenic variants. It also supports the scoring of microsatellite instability (MSI) and tumor mutational burden (TMB).What

Dr. Kristen Lynch is a Professor and Chair of Biochemistry and Biophysics at the University of Pennsylvania. Kristen’s research focuses on alternative splicing. Her lab is investigating how cells decide when to use an entire portion of the DNA instruction manual versus when to exclude parts of the instructions that are not useful or would be harmful. In particular, Kristen is interested in alternative splicing in the immune system and what happens when cells are faced with an immune challenge. When

Listen to Part I HERE*Andy McIntosh, PhD:This weekFred Williamsis on assignment soDoug McBurneywelcomesa brilliant mind in science and design —Dr. Andy McIntosh. He’s a professor of thermodynamics and combustion theory, and he joins RSR to help us understand one of the most sophisticated combustion engines ever observed!Hestatesin his biography that: “At Bangor University in North Wales in the early 1970s... ...At that point we only had Whitcomb and Morris’ book, ‘The Genesis Flood’,

#271: Author of "The Cat Men of Gotham," Peggy Gavan leads cat-centric, architectural and historical walking tours of three different Manhattan neighborhoods at Cats About Town Tours.

Discover how ethical consumerism supports human rights and personal flourishing through humanistic values and a secular worldview.

Dr Rachel Reid-McCann (University of Oxford, Oxford, UK) speaks with Acting Editor-in-Chief Ali Landman about her recent paper "Longitudinal association between dysmenorrhoea in adolescence and chronic pain in adulthood: a UK population-based study".

Host: Diego Maselli, MD, FCCP Guest: Stephanie Christenson, MD Despite triple inhaled therapy, many patients with chronic obstructive pulmonary disease (COPD) continue to experience frequent and severe exacerbations, leading to hospitalizations, symptom burden, and higher mortality risk. In this expert-led discussion, Drs. Diego Maselli and Stephanie Christenson personalized treatment approaches and the role of biologics in advanced COPD care. Dr. Maselli is a Professor of Medicine

Episode Summary:Benoy sits down with Dimitrios Parikos, Senior Managing Director for Global Energy & Climate Tech Practice at Brown & Brown Risk Solutions, to unpack how insurance fits into underwriting, what coverages matter from construction through operations, how to navigate hail/wildfire risk, and why engaging a broker early protects your projects. Biographies Benoy Thanjan Benoy Thanjan is the Founder and CEO of Reneu Energy, solar developer and consulting firm, and a strategic

Pa'Ris'Ha and her international panel of Co-hosts explore chapter three of "The Heartmath Solution" by Doc Childre and Howard Martin, with Donna Beech.Are our emotional states communicated through the electromagnetic field that surrounds us? How does our heart react to and transmit positive and negative emotions in ourselves and others? Join Pa'Ris'Ha and Co-hosts Geraldene Dalby-Ball, Sydney AUS; Tryna Cooper, Denver CO; Gabrielle Thompson, Mt. Beauty, AUS; Evelyn Yllada, Miami FL, and Marianne

The genetically engineered microbes we discussed in Part One of this report aren’t just wiping out the natural biosphere to fix nitrogen. In this video we’ll explore the DOD’s Tellus project that offers a blueprint to the microbial architecture of the global bio-surveillance system, and how this design has been implemented and is now being […]