Guest: John Cho, MD, PhD, FRCPC Could lower doses of radiation help optimize immune response in mesothelioma? Dr. John Cho joins us to explain how tailoring radiation to a tumor’s inflammatory and immunogenic characteristics could help modulate antitumor immunity while reducing the potential for fibrosis and treatment-related toxicity. Dr. Cho is a radiation oncologist at the Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the

Guest: Angel Qin, MD The treatment landscape for ALK+ metastatic non-small cell lung cancer (mNSCLC) is continuing to evolve, with durable outcomes from frontline ALK inhibition and emerging therapies offering new possibilities across disease settings. Join Dr. Angel Qin, Clinical Associate Professor of Internal Medicine at the University of Michigan Medical School, as she examines the evidence on current and emerging treatment options for this population.

Guest: Angel Qin, MD Even with increasingly effective targeted therapies for ALK+ metastatic non-small cell lung cancer (mNSCLC), unanswered questions remain, especially when a patient's disease progresses or treatment becomes difficult to tolerate. In this program, Dr. Angel Qin looks beyond current care strategies to consider where the field is headed, from overcoming resistance to investigating entirely different ways of extending disease control. Dr. Qin is a Clinical Associate

Guest: Angel Qin, MD Checkpoint inhibitors have shown limited efficacy in ALK+ metastatic non-small cell lung cancer (mNSCLC), but could a different immunologic strategy complement targeted therapy? Dr. Angel Qin discusses the rationale for ALK vaccines and explains how harnessing an ALK-specific immune response may help extend the durability of ALK TKI therapy. She's a Clinical Associate Professor of Internal Medicine at the University of Michigan Medical School.

Der Weltraum ist längst kein unberührter Ort mehr. Seit dem Start des ersten Satelliten Sputnik 1 im Jahr 1957 ist es im Erdorbit immer voller geworden. Und mit der wachsenden Nutzung des Weltraums hinterlassen wir dort auch immer mehr Spuren. Über diesen Weltraummüll haben wir mit Tim Flohrer von der Europäischen Weltraumorganisation ESA gesprochen.*** Ein Beitrag von Kim Hermann, gesprochen von Ulrike Kapfer. Aufnahme: Das Hörspielstudio Kreuzberg, Tonbearbeitung und Schnitt: Elias

再见了，平哥

Probably not bipedal, but could be digital.

被辣到满头大汗又停不下筷子？把不同辣椒里的辣椒素调到同样浓度，实际辣度却相差很大——说明辣椒里还有别的成分在悄悄拉低辣度。研究者从大量化学成分里锁定了几种天然化合物，它们能显著减轻灼热感；单独尝却几乎没有任何味道，说明不是"以味遮味"，而是在辣椒素受体这个"火警报警器"上抢先占位，让警报没那么响。有些辣椒之所以不辣，未必是辣椒素少，也可能是自带的解辣成分多。

“NZ in the Dock” The EU NZ fair Trade Agreement complaint – Government legislating to stop the Mike Smith case from proceeding – importance of government heeding evidence – lobbying influence in New Zealand politics – NZ’s Zero Carbon Act – forestry and the ETS – the roles of central and local government – train MPs in good

Un vieux modèle informatique, longtemps moqué, vient d'être comparé aux chiffres réels de notre monde. Que disait exactement ce fameux rapport de 1972 ?

Une découverte exceptionnelle de restes et d'outils de Dénisoviens; la création de transistors mous pour la nouvelle génération d'implants cérébraux; les capacités de reconnaissance de soi chez les animaux; et les effets du jeu libre et du jeu risqué sur le développement de l'enfance.

| Willie Nelson | Panorama de Noticias Apícolas – PNA | Amelia Tor Pisano CT con el Ing. Agr. y Dr. Cs. Agr. Lucas Garibaldi de la UBA y es investigador principal en CONICET | Entrevista La Miel en tu radio: Mec. Automotor Jorge Luis Gonella, diez años que realizamos pinza de alta calidad Api-Bell de Bell Ville, Córdoba Argentina | Entrevista La Miel en tu radio: Biol. Natalia Diaz Luis, especializada en abejas, conservación y apicultura ecológica, Fundadora de ecoalpispa de Canarias - España |

In this episode, Drs. Amirtha Chinnadurai and Jason Misurac are joined by Dr. Laurel Willig to discuss APOL1-mediated kidney disease in children. They discuss how to conceptualize APOL1 disease, emerging targeted therapies and clinical trials, and practical considerations for genetic testing and counseling families.00:00 Introduction 01:14 Understanding APOL1 Disease 08:58 APOL1 Phenotypes and Precision Medicine 13:07 Emerging APOL1 Therapies 18:01 Clinical Trials and Pediatric Patients 20:35

Haben wir das Langweilen verlernt? Kathrin Hönegger und Tobias Müller testen, warum Langeweile so schwer auszuhalten ist – und warum gerade darin Kraft für Kreativität und Veränderung steckt. Lieber Stromschlag als Langeweile Kann Langeweile so unangenehm werden, dass Menschen sich freiwillig einen Stromschlag verpassen? «Einstein» zeigt überraschende Experimente aus den USA und fragt: Warum ist es für viele so schwer, mit Langeweile umzugehen? Und wann wird sie zum Auslöser für schlechte

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Bob Tesh dies

L’Ivresse Sauvage : La quête oubliée de la conscience altéréeIl y a un besoin que l’on a longtemps cru exclusivement réservé à l’espèce humaine : le désir de s’évader. La volonté de lâcher prise, de briser un instant le poids du quotidien et d’altérer la perception du réel grâce à des substances extérieures. De la fermentations des fruits aux décoctions psychotropes, l’humanité a empilé les théories pour expliquer cette quête d’ivresse — y voyant tantôt une faiblesse morale, une

生气了去跑步、打沙袋发泄？科学家研究的结论可能刚好与你的认知相反：深呼吸、正念、冥想、渐进式放松、慢瑜伽这类降低生理唤醒的方法，能显著减少愤怒与攻击性，不同性别、年龄、背景的人都稳定有效；而打沙袋、骑车这类升高唤醒的活动整体几乎无效，慢跑甚至可能让怒气更旺。有意思的是，体育课、球类这类带"玩"的性质、能带来正向情绪的活动，反而有轻度降火的效果。情绪＝生理唤醒＋认知标签，先降唤醒，愤怒就少了燃料。

Listen Now to 028 WTFutureWatch 028 WTFuture Watch Segments of 028 WTFuture In this episode we dive headfirst into how AI tools and narrative editing are transforming the way we record our lives and communicate. Al has been bringing incredible AI-generated visual enhancements to life—from 3D face-tracking models to animating historical 1900s photos of Santa Cruz—elucidating complex ideas far better than speech alone. Beyond refining our cinematic timing, pacing, and visual storytelling,

The water breaks at 30 weeks. The baby's head is in the fundus at 37. The ultrasound shows one placenta and two babies. Each one changes the delivery plan, and one number decides it every time.The post 173 PROM, Breech and Twins for the PANCE appeared first on Physician Assistant Exam Review.

Météo-France a publié vendredi son bilan pour ce mois de septembre, et les chiffres donnent le vertige. À quel point ce mois de septembre restera-t-il dans les annales ?