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PODCAST

This Week in Startups

Jason Calacanis

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

technology

All Episodes

01:22:11

Behind the Scenes with an early OpenClaw contributor!...

This Week in Startups ·

2026/02/26

This Week In Startups is made possible by:Lemon IO - https://Lemon.io/twistEvery.io - https://every.io Sentry.io- https://sentry.io/twistToday’s show:We’re going behind the curtain today — it’s a packed show!We found Tyler Yust, OpenClaw’s third EVER contributor to share his insights from within foundation! We’ve got Deedy Das, of Menlo Ventures, on the show to discuss whether SaaS is cooked! Next we met the creator of an OpenClaw instance that fits in your pocket! We’ve also got the founder of

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01:18:57

Kill Your Startup’s Knowledge Chaos with OpenClaw...

This Week in Startups ·

2026/02/24

This Week In Startups is made possible by:Caldera Lab - [calderalab.com/twist](https://calderalab.com/twist)Iru - [iru.com](http://Iru.com/twist)LinkedIn Jobs - http://linkedin.com/twist*OpenClaw is incredible at automating tasks. But what if it could also fix your startup’s internal communication problems? Give agents shared memory, and you may be able to break down information silos while ensuring that teammates have the same context.@oliverhenry and @jeffweisbein demo what they’ve actually built

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01:08:36

We Asked 3 Experts How to Get More Value out of...

This Week in Startups ·

2026/02/21

This Week In Startups is made possible by:Gusto - https://Gusto.com/twistCircle - https://circle.so/twistNorthwest Registered Agent - https://northwestregisteredagent.com/twistToday’s show:*Getting OpenClaw set up and running without destroying your bank account is one thing.But now that you have your agent or swarm operational, how can you use them to get real work done?We have three builders who are going to show you how to maximize your OpenClaw output!GUESTS:Jordy Coltman: Viral X author and

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01:02:26

When Will Openclaw go Mainstream? | E2252

This Week in Startups ·

2026/02/19

This Week In Startups is made possible by:Gusto - Try Gusto today and get 3 months free at http://uber.com/ai-solutionsCrusoe Cloud - Reserve your capacity for the latest GPU’s at http://uber.com/ai-solutionsUber AI Solutions - Book a demo today at http://uber.com/ai-solutions*Today’s show: It’s a packed show! We’ve got YouTuber and Openclaw enthusiast Matthew Berman, Ryan Yaneli, founder of Nextvisit, and Jason Grad, founder of Massive! We’re all in on Openclaw, but we have no doubts there’s still

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01:26:33

Will OpenAI Tank OpenClaw? | E2251

This Week in Startups ·

2026/02/17

Will OpenAI Tank OpenClaw? | E2251This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistLemon IO - https://lemon.io/twistLinkedIn Jobs - http://linkedin.com/HiringProOfferToday’s show:*OpenAI hired OpenClaw creater Peter Steinberger. What does this mean for the future of the AI virtual assistant platform, and what can the OpenClaw community do TODAY to help protect their favorite free, open-source resource?Jason and Alex consider the

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01:06:28

OpenClaw is Our Friend Now | E2250

This Week in Startups ·

2026/02/14

This Week In Startups is made possible by:Sentry - http://sentry.io/twistCircle - http://Circle.so/twistWispr Flow - https://wisprflow.ai/twistToday’s show: What makes OpenClaw feel so much more ALIVE than other AI agents?On TWiST, we’re welcoming three amazing builders who are truly connecting with their OpenClaw bots, not just using them for productivity but getting to know them and their personalities on a deeper level.Serial entrepreneur Ryan Carson shows us Antfarm, which creates a team of

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00:40:27

Why J-Cal Invested to 200K in a former Employee | E2249

This Week in Startups ·

2026/02/12

This Week In Startups is made possible by:NetSuite - https://www.netsuite.com/twistLuma AI - https://lumalabs.ai/twistSquarespace - https://squarespace.com/twistToday’s show: On today’s epsiode of TWiST, Jason gets pitched by two top founders, Presh Dineshkumar and Peter Cetale! Presh used to work for Jason at Launch! When he left, Jason invested $200K into Presh’s new startup The Wellness Company. Presh pitches Jason on what he has been building, and Jason gives Presh advice for improving the

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00:45:04

How These 3 Founders are building on Open Claw | E2248

This Week in Startups ·

2026/02/12

This Week In Startups is made possible by:Hubspot - http://clickhubspot.com/twist2Deel - http://deel.com/twistIru - http://www.iru.com/Today’s show: Today on TWiST we’re joined by 3 founders building on Open Claw, Presh Dineshkumar, Vishnu, and Sean Liu!First, long time friend of the pod, Presh Dineshkumar, shows us how he’s using Open Claw to automate his work at The Wellness Company. His Open Claw agent, Eywa, lives in his email and in his product, able to compile user lists at his

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01:07:58

Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn...

This Week in Startups ·

2026/02/10

This Week In Startups is made possible by:LinkedIn - http://linkedin.com/twistEvery.io - http://every.io/Northwest registered Agent - www.northwestregisteredagent.com/twistToday’s show: Sean Liu gave his OpenClaw “eyes” by hooking the AI assistant up to his Meta Ray Bans. While Jason and Alex consider the implications… guest expert Alex Finn quickly loses interest…It’s another All-Clawdbot TWiST where we debate the most essential uses for the viral agent platform. For their part, Alex Finn and Matt

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01:10:51

We built OpenClaw Ultron to replace 20 people at our...

This Week in Startups ·

2026/02/07

This Week In Startups is made possible by:Crusoe Cloud - https://crusoe.ai/savingsLemon IO - https://Lemon.io/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistThanks to our guests:Alex Cheema of ExoLabs http://exolabs.netRyan Yanneli of NextVisit https://nextvisit.ai/Today’s show: It’s the Age of Ultron at TWiST and LAUNCH. We’ve given our OpenClaw digital Replicants the keys to all of our systems and we’re seeing how much of our jobs they can really do when left to

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00:53:41

Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) |...

This Week in Startups ·

2026/02/04

This Week In Startups is made possible by:Circle - http://Circle.so/twistCaldera Lab - http://calderalab.com/TWISTLinkedIn - http://linkedin.com/twistToday’s show: There was a time, not long ago, when offices everywhere came to a standstill, and everyone became even more fixated on their phones than usual, each time HQ Trivia went live. The app-based game show was a massive viral hit… until suddenly, around a year later, it wasn’t.Now, HQ Trivia host Scott Rogowsky is back with a new concept: Savvy,

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01:07:08

Where early-stage founders MUST focus to success | E2244

This Week in Startups ·

2026/02/03

This Week In Startups is made possible by:Quadratic - http://quadratic.ai/twistToday’s show: Don’t get distracted! Here are the MOST CRUCIAL aspects of running a startup, where founders need to keep their full and uninterrupted focus.- Make sure you’re saving up your cash- Why you need to just get started and build SOMETHING- Trust and reliability is EVERYTHING for new products- Why distribution should be your top priorityDownload all this practical and tactical startup advice from seasoned veterans

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01:02:11

SpaceX + xAI deal gets us one step closer to Musk...

This Week in Startups ·

2026/02/03

This Week In Startups is made possible by:Uber - http://uber.com/twistDeel - http://deel.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: SpaceX is buying xAI, forming a mega-corp that plans to launch data centers into SPACE. Will Tesla also join up, fulfilling Elon’s destiny to become real-life Tony Stark, with his own Musk Industries? Jason and Alex break down the future of SpaceXAI in a breaking news report.THEN, we’re still celebrating OpenClaw

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01:28:26

AI Bots Take Over | E2242

This Week in Startups ·

2026/01/31

This Week In Startups is made possible by:Deel - http://deel.com/twistLinkedIn Jobs - http://linkedin.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: On Today’s action packed episode of This Week in Startups, our team is going full AI!Jason is joined by Oliver Korzen and Lukas Durand from the LAUNCH team, alongside Rahul Sood, founder/CEO of Irrevernt Labs and founder of Voodoo PC.With the rise of Clawdbot/Moltbot, the question on everyone’s mind is

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00:55:31

How decriminalization led to an explosion in cannabis...

This Week in Startups ·

2026/01/29

This Week In Startups is made possible by:Gusto - http://Gusto.com/twistZite - http://zite.com/twistCircle.so - http://circle.so/twistGuest links: Andrew Duffy, Founder and CEO, http://sparkplug.app — Retail incentives and brand partnerships platformFord Smith, Founder of http://Ultranative.com — Investing in transformative startupsSocrates Rosenfeld, Founder and CEO of http://iheartjane.com — One stop shop for cannabis productsToday’s show: On TWiST’s first Cannabis Roundtable, Jason is joined by

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01:02:14

Clawdbot is an inflection point in AI history | E2240

This Week in Startups ·

2026/01/27

This Week In Startups is made possible by:Quo - http://quo.com/TWiSTLemon IO - https://lemon.io/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: Jason is back from Davos and Tokyo! We are jumping right back in with a group of Clawdbot power users: Alex Finn, Matt Von Horn, and Dan Penguine.Clawdbot is a hot open source AI project that lets users automate… everything! Dan helped his automate his aging parent’s tea shop, Matt built news sourcing bots, and

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01:03:23

Why You’ll Choose an AI Doctor (feat. Fred Almeida...

This Week in Startups ·

2026/01/24

This Week In Startups is made possible by:Sentry.io - sentry.io/twistHubspot - clickhubspot.com/twist2Northwest Registered Agent - https://northwestregisteredagent.com/twistToday’s show:One day soon, you might consult an AI general practitioner about your health, and then the computer will recommend human specialists to take up your case.On TWiST Tokyo, Jason chats with Fred Almeida — founder and CEO of American Medical Intelligence Inc. — and Maxwell Weiss, a partner at Pacific Bays

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01:03:33

From Blood Transfusions to Burritos, How Zipline is...

This Week in Startups ·

2026/01/21

This Week In Startups is made possible by:Northwest Registered Agent - www.northwestregisteredagent.com/twistCrusoe Cloud - https://crusoe.ai/savingsLinkedIn Jobs - http://linkedIn.com/twistToday’s show: On today’s TWIST episode, Alex interviews two of the top startup co-founders: Keller Cliffton of Zipline and Anastasis Germanidis of Runway. Zipline announced its $600 million raise at a $7.6 BILLION valuation. Kellers breaks down the origins, economics, and future of Zipline’s contrarian bet in

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00:57:35

How startups suddenly became “cool” in Japan (feat....

This Week in Startups ·

2026/01/20

This Week In Startups is made possible by:Circle.so - http://Circle.so/twistDeel - http://deel.com/twistUber AI Solutions - http://uber.com/twistToday’s show:Not long ago, promising young Japanese graduates wanted to go work for the largest, most established, and even oldest corporations: Sony, Mitsubishi, and the like. But now, just over the last few years, more and more Japanese people are becoming entrepreneurs and founders. TWiST Japan continues with a fascinating look inside the country’s

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01:03:25

Avoiding buzzwords and marketing-speak (feat. Thomas...

This Week in Startups ·

2026/01/16

This Week In Startups is made possible by:Lemon.io - https://lemon.io/twistDeel - http://deel.com/twistLinkedIn Jobs - http://linkedIn.com/twistToday’s show: Some pitches sound just like ads… and it’s a huge red flag for investors.On our latest edition of TWiST Tokyo, Jason welcomes legendary angel investor (and long-time friend of the pod) Thomas McInerney. His list of investments reads like a Who’s Who of the tech elite, including Notion, SpaceX, Uber, OpenAI, Anthropic, and Perplexity….At Founder

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