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PODCAST

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade,Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -has redefined what’s possible for the human mind and body. After more than a thousand episodes ofBulletproof Radio, he’s taking it to the next level withThe Human Upgrade™- a masterclass inbiohacking, longevity, and performance optimization.Each episode explorescutting-edge science, advanced technology, and proven biohacksto help youupgrade your energy, focus, metabolism, and resilience.You’ll

health & fitness self-improvement

All Episodes

00:46:56

How to Gain SUPERHUMAN Hearing (With Very Little...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/31

Your hearing isn’t just about sound—it’s the key to sharper focus, deeper connections, and increased awareness. In this episode, Dave explores the cutting-edge world of hearing technology with Brandon Sawalich, CEO of Starkey, and reveals how you can gain superhuman hearing with almost no effort.“Listening” to this episode is going to be one of the best things for your hearing. But why? Because your hearing isn’t just about detecting sounds—it’s about transforming the way you experience the

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01:15:30

How to STOP Living in Fear and Find Your Purpose in...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/26

Fear is quietly running your life—and it’s holding you back from the purpose and success you deserve. In this episode, we revisit Davechatting with one of the keynote speakers for the Biohacking Conference 2025, Ryan Holiday, the bestselling author ofCourage Is Calling, to tackle the one thing standing between you and your potential: fear.Why should you listen? Because fear is the root cause of procrastination, self-doubt, and the endless excuses that keep you stuck. Ryan reveals why

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00:57:27

Ditch the 10,000-Hour Rule & Escape Failure Porn for...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/24

Today we are bringing back one of our all-time favorite episodes with James Altucher.Dave sits down with James, an entrepreneur, bestselling author, and master experimenter, to uncover why the 10,000-hour rule might just be holding you back. Instead of grinding your way to expertise, James reveals his 10,000 Experiment Rule—a game-changing approach to mastering any skill faster than you thought possible.From comedy stages to boardrooms, James has redefined success through relentless

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01:29:55

How to HACK Your HATE with Daryl Davis (The Jazz...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/19

Can you use hate to make the world a better place? Daryl Davis, a world-class jazz musician, didn’t just confront hate—he dismantled it. By sitting down with over 200 Ku Klux Klan members, he inspired them to leave their robes behind. But this isn’t just a story about racism or redemption; it’s a story about the incredible power of human connection and the lessons it holds for all of us.In this special episode, Dave explores how Daryl turned impossible conversations into transformative

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01:21:25

Why 50% of Us Won’t Live Past 76—And How to Beat the...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/17

Is AI About to Replace Your Doctor? Or Save Your Life?The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180?In this episode, Davesits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technology, longevity,

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01:08:51

Here’s How to Get the ULTIMATE Liver (And Why It Will...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/13

Most people don’t think about their liver until it’s too late.In this episode, Dave sits down with Siggi Clavien, founder ofde-liver-ance®& The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity.Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the liver’s regenerative

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00:23:58

Ex Google-Exec: AI is Going to Kill Us in 2027. (Only...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/12

Will the next nuclear bomb be AI Superintelligence?The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take?In this episode, Mo Gawdat, bestselling author ofScary Smartand former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redefining what it means to

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01:06:59

How Google X’s Mo Gawdat Made 1 Billion People...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/10

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How.I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works.Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy.Mo dives into

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01:43:01

Is Red Meat the Fountain of Youth? Paul Saladino : 1229

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/05

Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit? Today we are excited to have Paul Saladino join us for a masterclass on food and diets.Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better

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01:10:57

Why is your Oral Health KILLING you, and what can you...

The Human Upgrade: Biohacking for Longevity &... ·

2024/12/03

What are the oral hygiene tips that could save your life? Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these

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01:12:06

What You DON'T Know About Women’s Health! From...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/28

Is this the missing link in fertility?The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes.Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic

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01:07:18

The World’s BEST Alcohol Alternative. Pleasure,...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/26

Is alcohol losing its grip as the go-to social drink?Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity.In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why

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00:58:46

Urolithin A’s Secret to YOUTHFUL ENERGY and the Fight...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/22

Have we finally discovered the key to youthful energy, longevity, and cellular health?In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function,

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01:11:01

Exosomes vs Stem Cells and LIFE-CHANGING Advice with...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/21

Are exosomes the planet’s ultimate healing tool?!In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing, explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells.BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights

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00:49:51

Is Infrared Light the KEY to Longevity? Detox,...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/19

Is biohacking your sweat the secret to vitality?Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level.Here’s what you’ll learn in this episode:• Why infrared saunas excel at detoxing heavy metals and toxins• How they mimic exercise

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01:45:53

How to Discover What You TRULY Want—and Ask for It!...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/14

What if you could command any room and set boundaries without saying a word?Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across

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01:24:02

How to Optimize Your Brain for WORK: Achieving...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/12

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless?In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can

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00:34:23

Tim Ferriss: Smart Drugs, Insect Protein, Sex, and...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/07

What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make?In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance.They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect protein,

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01:18:27

Happiness Hacks That Actually Work (And What You’re...

The Human Upgrade: Biohacking for Longevity &... ·

2024/11/05

What if everything you believe about happiness is wrong?In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want, Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom.Together, Dave

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00:59:53

Learn How to HACK Your Mind with Hypnosis: The...

The Human Upgrade: Biohacking for Longevity &... ·

2024/10/31

Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade, you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing.Discover how hypnosis, unlike

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223 results

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