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PODCAST

Dr RR Baliga"s "Got Knowledge Doc" Podkast

Dr RR Baliga, MD, MBA

"Got Knowledge Doc" Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Each

science natural sciences

All Episodes

05:21

From Mom or Dad? It Makes a Difference whether Growth...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/08

🚀 New in Nature: Groundbreaking study reveals how the origin of your genes — from mom 👩‍🍼 or dad 👨‍🍼 — can push human growth 📏 and metabolism 🔥 in opposite directions! 🧬 Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts — boosting traits when inherited from one parent, reducing them from the other. ⚖️ Findings support the parental conflict hypothesis: paternal genes tend to

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03:53

💊 Rx to Fork: Can Doctors Really Prescribe Dinner?

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/07

🚨 New AHA Scientific Statement 🚨 “Food Is Medicine” isn’t just a slogan—it’s a growing clinical movement. 🍎💉 This systematic review of 14 U.S.-based RCTs explores how Produce Prescriptions (PRx), Medically Tailored Groceries (MTG), and Meals (MTM) impact diet, food insecurity, and health outcomes. 📊 Results show improvements in diet quality and food security, with mixed effects on clinical outcomes. 🧠 Key takeaway: We need better-designed, longer-term trials and real-world implementation

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03:53

🥄 From Kitchen to Clinic: Food Processing Matters!

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/07

🔬 New study in Nature Medicine reveals that not all healthy diets are created equal — even when nutrient content is matched, 🍞 ultra-processed foods (UPFs) hinder weight loss compared to 🥗 minimally processed foods (MPFs). 📉 Participants lost twice as much weight on MPF diets, with greater reductions in fat mass and cravings. 🔍 This landmark trial urges public health policy to consider food processing—not just nutrients. 📎 A must-read for clinicians, policymakers, and anyone shaping the

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04:56

Systolic Heart Failure: “Improvement, Remission,...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/06

🚨 New Insights in Heart Failure Management! 💡🫀 Just explored the latest 2025 European Journal of Heart Failure review by Hulot et al. redefining how we view HF recovery. No longer just “improvement” – we now distinguish HFimpEF, remission, and recovery as stages along a phenotypic spectrum. 🔬 Key takeaways: ✅ Relapse still occurs in ~10%/year 🧬 TTN variants, GLS, and LA strain guide prognosis 💊 Stopping GDMT? Think twice (TRED-HF: 44% relapse!) Essential read for anyone managing HF

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05:21

Ovarian Cancer: 🎭 Courage, Cancer, & Comebacks

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/06

📘 New JAMA Review: Ovarian Cancer – From Symptoms to Survival 🌸 Approximately 21,000 women are diagnosed with ovarian cancer annually in the U.S.—and 80% present with advanced-stage disease. The latest JAMA review by Caruso, Weroha, and Cliby (2025) offers a comprehensive update on: 🧬 Evolving genetic insights (BRCA1/2, HRD, Lynch) 🩺 Diagnostic strategies beyond CA-125 💊 State-of-the-art therapies: surgery, chemo, PARP inhibitors, bevacizumab 📉 Declining mortality trends due to prevention

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05:01

📉💪 Less Hospital, More Life: The Iron Fix for Failing...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/05

🚨 New Insights in Heart Failure Care! 🫀💉 A landmark meta-analysis in Nature Medicine shows that intravenous iron therapy significantly reduces heart failure hospitalizations and cardiovascular deaths — especially in the first year of treatment. 📉💪 With over 7,000 patients across 6 RCTs, this study reinforces IV iron as a safe, outcome-improving therapy in HFrEF with iron deficiency. 🔬✅ 💡 Curious about TSAT, RR, or sex-specific effects? 📊 This is essential reading for cardiologists,

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03:24

Dr. RR Baliga’s Philosophical Discourses: Anselm of...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/05

🚨 Spotlight on Medieval Thought! 🧠📜 Explore the legacy of Anselm of Canterbury—father of Scholasticism and originator of the Ontological Argument for God’s existence. His fusion of faith 🙏 and reason 🧩 shaped Western theology. 🎓 #Philosophy #MedievalStudies #Anselm #Theology

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03:15

Whirlwinds 🌬️, Wellness 💊, Cardiac Woes 😟

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/04

Tropical cyclones don’t just shake buildings — they shake hearts too. A powerful multicountry study in Science Advances links 🌊 storm exposure to a 13% rise in cardiovascular hospitalizations, especially ischemic heart disease and stroke. Vulnerable groups? Men, adults aged 20–59, and socioeconomically deprived communities. 🧠 The risk peaks ~2 months post-cyclone and lasts up to 6 months. 🧭 It’s time to rethink disaster response — beyond winds and water, to hearts and health equity. #Cardiology

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07:31

🚗💥 Zero Isn’t Impossible: Driving Toward Safer Roads

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/04

🚗 42,939 lives lost in 2021 — the U.S. motor vehicle fatality rate remains far higher than other high-income nations. The NEJM review on Motor Vehicle Crash Prevention highlights the Safe System Approach: 🛣️ Safer roads 🚘 Safer vehicles 👥 Safer people ⚡ Safer speeds 🚑 Better postcrash care 🔍 From graduated driver licensing to automated emergency braking (AEB) and driver-monitoring tech, the future of crash prevention lies in data, design, and shared responsibility. Question: What innovations

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07:43

A Hole, A Hope, A Hazard: Understanding PFO and Stroke

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/03

🎙️ New Podcast Episode! “Hole in the Heart, Stroke on the Brain, Science at the Core” 🧠❤️🔬 Discover how a tiny opening—present in 1 in 4 adults—can lead to devastating strokes 🩺⚠️. We unpack the latest JAMA review on PFO, cryptogenic stroke, and how RoPE and PASCAL scores guide who benefits from closure. 🎯💉 🔗 Tune in to learn about cutting-edge trials, real-world risks, and how precision matters in stroke prevention. #Stroke #PFO #Cardiology #Podcast #RoPE #PASCAL #ClinicalTrials

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04:49

📊 DNA, Diagnosis, and Dignity: Reframing Stuttering...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/03

🧬 Just explored the largest GWAS on stuttering—over 1 million participants! 🎵 Fascinating link uncovered between impaired rhythm and speech disfluency, supporting the Atypical Rhythm Risk Hypothesis. 🧠 Genes like VRK2 and FANCL connect beat synchronization and stuttering risk. 🚀 A big step toward precision care in developmental speech disorders. #Genetics #Stuttering #GWAS #Neurodevelopment #PrecisionMedicine #SpeechTherapy #RhythmAndSpeech

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08:42

From MRAs to ASIs: Rewriting Heart Failure’s...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/02

🎙️ From MRAs to ASIs: Rewriting Heart Failure’s Aldosterone Story 🚨 New Episode Alert! 🎧 Title: From MRAs to ASIs: Rewriting Heart Failure’s Aldosterone Story 💔🧬💊 In this episode of Got Knowledge Doc, we unpack the double-edged role of aldosterone in heart failure and kidney disease—from its genomic mischief to its nongenomic chaos via GPER. We dive into: ✅ Why MRAs aren’t enough 🔬 What ASIs bring to the table 📉 How new trials like FIDELIO, FIGARO, and PREVENT-HF are shaping the future If

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02:53

🚫💊➡️⚖️ Weight Regain After the The GLP-1 Stop

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/02

🚫💊➡️⚖️ The GLP-1 Comeback: Weight Regain After the Stop” 📊 Based on the 2025 BMC Medicine meta-analysis, we explore what happens after stopping anti-obesity meds like GLP-1 receptor agonists. 👀 Key takeaways: – Weight regain begins as early as 8 weeks after stopping – GLP-1 drugs show the highest rebound 📈 – Lifestyle changes alone may not prevent regain 🥗🏃‍♂️ – Long-term weight management may require long-term therapy 🔁 🎙️ Tune in to understand the science behind the yo-yo and what

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03:30

Move. Breathe. Beat Atrial Fibrillation 🏃‍♂️🫀💥

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/01

🚨 Podcast Alert: “Move. Breathe. Beat AF 🏃‍♂️🫀💥” The latest Cochrane systematic review + meta-analysis shows that exercise-based cardiac rehabilitation (ExCR) meaningfully reduces: ✅ AF recurrence ✅ Symptom severity ✅ AF burden and frequency ✅ And improves VO₂ peak & mental health—all without increased serious events. 📢 Time to rethink rhythm control—beyond the pill and catheter. #AtrialFibrillation #Cardiology #ExerciseMedicine #CardioOncology #Rehabilitation #Podcast Let me know if

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05:44

GLP-1s, GI Woes, Great Gains 🧪

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/08/01

Titrate, Train, Triumph 🧬🏋️‍♀️🎯” Obesity medications like semaglutide and tirzepatide are game-changers—but managing GI side effects, sarcopenia risk, and long-term adherence requires nuance, nutrition, and teamwork. 💡 From nausea to nutrition, and from missed doses to muscle mass—this episode offers practical, evidence-based strategies to optimize incretin therapy. 💊🥦⚖️ 🎧 Tune in to learn how to tailor treatment, counsel patients, and build sustainable weight loss plans.

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04:33

🧠 Smart Lipids: ApoB and Lp(a) in the Age of Risk...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/07/31

🔬 New Insights in Lipidology! 🫀 A landmark study in European Heart Journal (2025) shows that Apolipoprotein B (ApoB) particle count is a more powerful predictor of coronary artery disease than traditional LDL cholesterol. While VLDL particles are more atherogenic per unit, LDL dominates by count — making total ApoB count + Lipoprotein(a) the gold standard for risk assessment. 🧪📊 👩‍⚕️👨‍⚕️ Time to rethink lipid panels and embrace particle-based precision. #Cardiology #Lipidology #ApoB #Lp(a)

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05:09

🧠💡 From Effort to Impact: : Lifestyle Lessons for...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/07/31

🧠✨ Just read a thought-provoking article in JAMA on the US POINTER trial! Structured lifestyle changes (think 🏃‍♀️🥗🧩) showed modest but real gains in cognition for older adults at risk of dementia. But here’s the twist: even light-touch self-guided changes yielded nearly similar benefits. 🤯 So… 💬 Is intensity always worth the investment? Or can simplicity scale smarter? 🔗 Worth pondering as we shape the future of brain health! #DementiaPrevention #CognitiveHealth #LifestyleMedicine

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04:19

Beyond Cholesterol 🌪️: 🇮🇳🩺: Lp(a)’s Reach in the...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/07/30

🔬 New Review Alert! 🫀 South Asians face one of the highest global burdens of premature heart disease — and Lp(a) may be the silent culprit. 📈 In a comprehensive JAHA 2025 review, researchers reveal how 25% of South Asians have dangerously elevated Lp(a) levels, doubling their risk of myocardial infarction. 🧬💥 Key takeaways: ✅ Lp(a) is genetically driven & unaffected by lifestyle ✅ Risk is underestimated by standard calculators ✅ Novel therapies (PCSK9i, siRNA, ASOs) are on the horizon ✅

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03:24

🏫 Early Edge, Not Late Armor — Why Brain Aging...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/07/30

📢 New insights on education & brain aging! 🧠📉 A mega-analysis across 33 countries (170K+ participants, 15K+ MRIs) shows 📚 higher education boosts baseline memory—but doesn’t slow brain aging or cognitive decline over time. ❌🧓 ✅ Early-life traits (like childhood cognition & environment) drive the advantage. 🔗 Education matters—but not in the way we thought. Full story: “Reevaluating the role of education on cognitive decline and brain aging” in Nature Medicine 🧬🌍 #CognitiveHealth

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02:50

📉 “Lp(a) is a Vascular Crystal Ball” 🚷🦿🛣️

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/07/29

🧬 Just dropped: our latest podcast episode 🎙️ dives into Lipoprotein(a) and its powerful role in predicting vascular disease beyond the heart 🫀—including PAD 🦵 and stroke 🧠. 📊 Based on a massive UK Biobank study (n=460K+), high Lp(a) levels (≥150 nmol/L) were linked to: • 18% ↑ risk of PAD • 17% ↑ risk of carotid stenosis • 60% ↑ risk of major limb events ⚠️ Lp(a) is more than a lab value—it’s a Vascular Crystal Ball. #LipoproteinA #PAD #Stroke #VascularMedicine #PrecisionCardiology

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