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PODCAST

Speaking of Mol Bio

Thermo Fisher Scientific

Speaking of Mol Bio, a podcast series from Thermo Fisher Scientific, discusses trending applications in science and the molecular biology aspects of those applications. Our host delves in to deep discussion with CEOs, R&D scientists, researchers, and key opinion leaders across the globe. Speaking of Mol Bio helps scientific curious people - from all scientific and non-scientific backgrounds - understand how modern molecular biology applications can help push the boundaries in medicine, science, drug

science life sciences

All Episodes

00:04:36

Season 3 spoilers – innovation, inspiration, and insight

Speaking of Mol Bio ·

2024/12/18

The start of Season 3 is just around the corner, slated to start in January 2025. What’s the new season hold in store you might ask? Steve assures us he’ll be back hosting Season 3 and teases at topics that are coming. These include biosecurity, bioengineering, polymer degradation, genetics of obesity, CROs and how they utilize mol bio, platelet biology, and epitranscriptomics. As if that were not enough to get you excited about the new season, Steve also teases on the inclusion of Mol Bio Minutes

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00:33:18

It’s all in your approach – biosynthesis of natural...

Speaking of Mol Bio ·

2024/11/15

We’re joined in this episode by Dr. Sarah Barry, Reader in Chemical Biology at King’s College London. Sarah started with an interest in biochemistry, went into organic chemistry because it was more concrete, and now applies her chemist’s approach to understanding and manipulating biosynthesis of natural products for important areas of research, including antibiotics. This insightful conversation gives a peek into the mind of a chemical biologist’s way of thinking about and approaching challenges

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00:31:58

The value of community – your microbiome

Speaking of Mol Bio ·

2024/10/15

The history of fermented foods like beer, bread, and other foods can be traced back thousands of years to ancient civilizations in China and Egypt. This ancient technology was originally used to preserve foods when refrigeration was not an option. While less common in modern industrialized civilizations, we’re now realizing that fermented foods play a major role in gut microbiome diversity, which is a biomarker for overall health. Join our conversation with Dr. John Leech, Technologist at Teagasc

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00:32:04

Therapeutic nucleic acids – a CDMO’s view on mRNA

Speaking of Mol Bio ·

2024/09/15

While some of us knew a good bit about mRNA prior to 2020, we all got a crash course on mRNA technology and its prophylactic and therapeutic potential as a result of the COVID pandemic and subsequent SARS CoV-2 vaccine development. In fact, most of us have now received at least one mRNA vaccine at this point. Our guest for this episode, Dr. Christian Cobaugh, Co-founder and CEO of Vernal Biosciences, was a passionate believer in mRNA medicines well before the pandemic. Join us to hear his story and

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00:35:29

A molecular thermometer for the future

Speaking of Mol Bio ·

2024/08/15

There are all sorts of molecular tests to tell if you’re infected with something specific, but what do you use when you’re not sure what you might have? You might use a thermometer as a first step, but wouldn’t it be nice if that thermometer was a bit more high tech? In this episode we meet Dr. Nick Meyerson, CEO and co-founder of Darwin Biosciences, who’s team is working to develop the “molecular thermometer of the future.” We hear about how this physicist transitioned into molecular biology and

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00:32:58

Directed evolution – A PETase project

Speaking of Mol Bio ·

2024/07/15

Plastics are a modern miracle of science that have helped deliver both convenience and life-saving solutions. However, we must now grapple with the challenge of immense amounts of plastics in our waste streams and environment. How do we best deconstruct plastics to reusable or more bio-friendly molecules? This is the exact challenge being addressed by the work of Dr. Elizabeth (Izzy) Bell and her team at the National Renewable Energy Lab. Our conversation with Izzy showcases her ability to

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00:32:37

Scientific marketing in the century of the biotech...

Speaking of Mol Bio ·

2024/06/15

Most scientists start their education and careers with a vision of working in the lab to discover great things and drive innovation. However, we don’t all end up loving the actual lab work portion of science. What non-lab career options exist to utilize molecular biology knowledge and skills? Well, according to our guest, Jason Amsbaugh, Founder and CEO of Samba Scientific, the career options are far more plentiful than you may think. Scientific marketing, according to Jason, is one such role that

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00:34:47

Cheers to molecular Biology

Speaking of Mol Bio ·

2024/05/15

While the end product is quite different, brewing beer is not all that different than many other bioproduction processes used in the lab and industry. Both require skills, experience, and the right QC/QA methods to control and monitor the starting materials and the entire process, all the way to that bottle of suds you might be thirsty for. Steve and Gabriel talk with Kelly Tretter, a microbiologist with more than 30 years of experience in the brewing industry, to discuss brewing at the molecular

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00:32:10

Unsung heroes of food health and safety

Speaking of Mol Bio ·

2024/04/15

When you buy chicken or turkey from the grocery store, you might not give it much thought, but there is an entire network of people working to ensure the health of the animals in our food supply chain and your health. In this episode, we talk with an unsung hero, Beverly Wood, supervisor of the molecular diagnostics lab at the North Carolina Department of Agriculture and Consumer Services, who works tirelessly to ensure the health and safety of poultry and livestock animals in our food supply chain

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00:31:53

Molecular Biology for hire – the CRO experience

Speaking of Mol Bio ·

2024/03/15

Contract Research Organizations (CROs) are a resource that most scientists know about but relatively few have first-hand, internal experience with. In this episode our hosts speak with Saboor Hekmaty, Director of Laboratory Operations at Avrok Biosciences, who pulls back the curtain to illuminate what CROs do, and the skills required for them to be successful in supporting diverse projects for their customers. We hear about the work Saboor and their team do in biospecimen processing, biobanking,

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00:31:56

High-throughput transcriptomics and AI for drug...

Speaking of Mol Bio ·

2024/02/15

Doing something complex and meaningful in a new way requires thinking and acting a bit differently. This is the case with how Dr. Joey Azofeifa, from Arpeggio Bio, is using systems biology to discover new drug candidates. Join us in this Season 2 kickoff episode where we dive headlong into transcriptomics, systems biology, machine learning, and learn how they’re being used to innovate drug discovery. We learn about 3’-end mRNA barcoding and in-cell reverse transcription methods that allow the

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00:02:40

Season 2 Teaser

Speaking of Mol Bio ·

2024/02/12

We start the second season of this series with an update on what you can expect from new episodes, which start to drop soon.Your host, Steve Lewis, shares details on changes you can expect as the series evolves. One change will be a broadening of application topics to be covered, as this season will include episodes discussing transcriptomics in biopharma, the use of molecular biology by CROs, brewing, food testing, food production, biosecurity, and non-bench careers that use molecular biology

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00:30:56

A look into the fruit bowl of biology

Speaking of Mol Bio ·

2023/09/15

In this episode of Speaking of Mol Bio, we speak with Dr. Mandovi Chatterjee about single cell analysis. Dr. Chatterjee is the Director of Single Cell Core at Harvard University Medical School. She has spent her career at the exploring and mastering a wide variety of single cell methods . In conversation with Dr. Chatterjee, our hosts dive into the more technical aspects of this ever-evolving field. We also learn an interesting analogy to better understand the difference between bulk and

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00:38:45

The intersection of biology and technology

Speaking of Mol Bio ·

2023/08/15

In this episode, the hosts have an intriguing discussion with Dr. Ben Sun, Head of Biomarker Genetics at Biogen. Dr. Sun holds an MD/PhD from the University of Cambridge, providing a view and perspective on data from both research and clinical perspectives. The advantage of his unique background is that it provides a balanced perspective on large-scale population data and genomic data sets used to train computational models for predicting and informing clinical treatment. The conversation touches

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00:31:59

Multi-omics | The molecular biology of plants in space

Speaking of Mol Bio ·

2023/07/15

Dr. Stan Roux, Professor of Molecular Biosciences at the University of Texas – Austin, has had a long and successful career based on his fascination with plants and his desire to understand plant biology. He’s spent his career exploring the effect of apyrase on root systems, crop yields, and plant nutrient uptake. We get into Stan’s unlikely career path and how a chance conversation with a colleague at a conference led to his 25 years of collaboration with NASA and experiments on space missions to

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00:31:39

CRISPR | An insider’s perspective on CRISPR

Speaking of Mol Bio ·

2023/06/15

In this episode, Gabriel and Steve welcome a colleague of theirs, Dr. Doris Beylkin, to share her depth of knowledge and perspective on the CRISPR cell engineering topic. While Doris is a Global Market Development Manager today, she has over 10 years of experience supporting customers in planning, troubleshooting, and analyzing gene modulation and gene editing experiments. In this regard, she’s seen and it all, and has pearls of wisdom and insight to share on the topic. The discussion covers CRISPR

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00:32:11

Exosomes | The early realization of the exosome’s...

Speaking of Mol Bio ·

2023/05/15

This discussion with Dr. Johan Skog covers a lot of ground while staying super approachable. The Founder and Chief Scientific Officer of Exosome Diagnostics, starts by sharing basics about exosomes and tells us about how he’s translated his curiosity for the vesicles from tumor stem cells into his current role where he’s helped develop the world’s first exosome-based cancer diagnostic test. The conversation delves into the variations in exosomes populations, the value of using multiple biomarkers in

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00:32:09

Exosomes | Exploring the body’s extracellular...

Speaking of Mol Bio ·

2023/04/15

It’s been 40 years since extracellular vesicles, or exosomes, were first connected to the way cells communicate and transfer information. Since then, researchers have studied what part they play in the normal physiology of a cell. There has also been an expanding amount of work in the role that exosomes can play in therapeutics and diagnostics of a wide range of diseases. Jim West, CEO of Clara Biotech, joins us to share his perspective on research and innovation using exosomes as well as life in a

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00:33:01

Multi-omics | Investigating the body’s internet

Speaking of Mol Bio ·

2023/03/15

Multi-omics is a great example of how the scientific community is thinking larger and using complementary methods to gather deeper information to understand biology and inform medicine. Proteomics is just one of the -omes of multi-omics but it’s the one that Steve Williams, Chief Medical Officer at SomaLogic, has over 30 years’ experience in. Steve joins us to share his story and insights on how protein biology complements genetic profiling to enable measurement of thousands of biomarkers to

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00:33:21

Multi-omics | The importance of science in data science

Speaking of Mol Bio ·

2023/02/10

In this episode, we talk with Chris Whelan about the data behind science. Chris is the Director of Neuroscience, Data Science & Digital Health for Research and Development at The Janssen Pharmaceutical Companies of Johnson & Johnson, as well as the Chair of the UK Biobank Pharma Proteomics project. He connects the dots between genomics and proteomics and clarifies how omics can be used to understand disease biology to inform drug development to treat disease. The conversation touches on the

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42 results

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