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PODCAST

Foundation Fighting Blindness

Foundation Fighting Blindness

The Foundation Fighting Blindness is the driving force in the global development of treatments and cures for blinding diseases. To learn more, go to FightingBlindness.org.

science

All Episodes

00:01:43

Ocugen Launches Phase 2/3 Clinical Trial for...

Foundation Fighting Blindness ·

2025/07/21

The therapy delivers copies of the RORA gene to address multiple disease pathways.

en

00:02:48

Nanoscope Begins Rolling BLA Submission to FDA for...

Foundation Fighting Blindness ·

2025/07/14

The company plans to complete BLA submission in early 2026.

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00:25:47

Eye on the Cure Podcast | Episode 88: Richard Small

Foundation Fighting Blindness ·

2025/07/11

July 11, 2025. Richard Small, CEO of Neurotech, talks to host Ben Shaberman about ENCELTO™, the first and only FDA-approved treatment for adults with idiopathic Macular Telangiectasia Type 2 (MacTel). The therapy is a tiny, implantable capsule, the size of a rice grain, that delivers neurotrophic factors to preserve the patient's retinal cells and vision. The approach was previously developed to treat retinitis pigmentosa and age-related macular degeneration.

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00:04:00

Atsena Gets FDA Nod to Expand XLRS Gene Therapy...

Foundation Fighting Blindness ·

2025/07/09

The expanded Phase 1/2/3 shortens time to potential FDA approval.

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00:18:54

Eye on the Cure Podcast | Episode 87: Dr. Philip Beales

Foundation Fighting Blindness ·

2025/06/13

June 13, 2025. Dr. Philip Beales, a co-founder of Axovia Therapeutics, talks to host Ben Shaberman about Bardet Biedl syndrome, ciliopathies, and his company's emerging gene therapy for Bardet Biedl syndrome type 1 (BBS1) which is moving toward a clinical trial.

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00:31:15

Eye on the Cure Podcast | Episode 86: Lenore von...

Foundation Fighting Blindness ·

2025/05/23

May 23, 2025. Lenore von Krusenstiern, MD, PhD, at BlueRock Therapeutics talks to host Ben Shaberman about the company's clinical trial for a photoreceptor replacement therapy for people with inherited retinal conditions such as retinitis pigmentosa and cone-rod dystrophy. The approach, which uses induced pluripotent stem cells to develop photoreceptor precursors, comes out of the lab of stem cell pioneer David Gamm, MD, PhD, University of Wisconsin-Madison.

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00:02:35

J&J’s XLRP Gene Therapy Didn’t Meet Primary Endpoint...

Foundation Fighting Blindness ·

2025/05/15

Despite missing the primary endpoint, the treatment improved vision for some patients.

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00:04:53

ARVO 2025 Highlight: PYC Reports Encouraging Phase...

Foundation Fighting Blindness ·

2025/05/13

The company is planning a Phase 2/3 clinical trial for therapy in late 2025.

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00:04:15

ARVO 2025 Highlight: Atsena’s XLRS Gene Therapy...

Foundation Fighting Blindness ·

2025/05/12

Part B of the trial will enroll nine adult patients as well as three pediatric patients.

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00:03:07

ARVO 2025 Highlight: Beacon Reports Encouraging...

Foundation Fighting Blindness ·

2025/05/09

The company is currently enrolling patients in its Phase 2/3 VISTA Clinical Trial.

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00:28:34

Eye on the Cure Podcast | Episode 85: Cindy Elden

Foundation Fighting Blindness ·

2025/05/09

Cindy Elden, who co-founded the Usher III Initiative with her late father, talks to host Ben Shaberman about her journey with Usher syndrome type 3 (USH3), the decades-long work and persistence of her non-profit, and the clinical trial it launched for an USH3 small molecule therapy.

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00:35:25

Eye on the Cure Podcast | Episode 84: Contact Congress

Foundation Fighting Blindness ·

2025/04/02

April 3, 2025. In this episode of Eye on the Cure, Jen Bernstein at Horizon Government Affairs, and Sharon King of Taylor’s Tale, talk to host Ben Shaberman about how to schedule and conduct a visit with your House Member in your local district to advocate for important issues. With federal eye research funding at great risk and a Congressional district work period coming in mid-April, now is an ideal time to schedule a visit with your House Member.

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00:33:18

Eye on the Cure Podcast | Episode 83: Michel Michaelides

Foundation Fighting Blindness ·

2025/03/20

March 21, 2025. Professor Michel Michaelides, a world-renowned clinical researcher for inherited retinal diseases at Moorfields Eye Hospital and University College London, talks to host Ben Shaberman about the extraordinary vision improvements for young blind children receiving gene therapy for Leber congenital amaurosis 4 (LCA4). Professor also talks about emerging therapies in clinical trials for X-linked retinitis pigmentosa and Stargardt disease.

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00:04:02

Luxa Reports Vision Improvements in Clinical Trial of...

Foundation Fighting Blindness ·

2025/03/11

Patients with worse vision at trial enrollment had greatest vision improvements.

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00:02:11

Neurotech’s Encapsulated Cell Technology Receives FDA...

Foundation Fighting Blindness ·

2025/03/07

The technology was previously funded by the Foundation for the treatment of retinitis pigmentosa and dry age-related macular degeneration.

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00:32:15

Eye on the Cure Podcast | Episode 82: Dr. Aaron Nagiel

Foundation Fighting Blindness ·

2025/03/05

March 7, 2025. Aaron Nagiel, MD, PhD, a retina surgeon at Children’s Hospital Los Angeles, talks to host Ben Shaberman about how gene therapy is administered to the retina, what the surgery and recovery is like for patients, and the vision improvements for young patients receiving LUXTURNA, the first FDA-approved gene therapy for the eye or an inherited condition. Dr. Nagiel also discusses other retinal gene therapies in clinical development.

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00:03:40

Adverum Advancing Wet AMD Gene Therapy into Phase 3...

Foundation Fighting Blindness ·

2025/02/28

In earlier clinical trials, the emerging gene therapy greatly reduced the treatment burden associated with injections of approved anti-VEGF therapies.

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00:03:03

LCA4 Gene Therapy Restores Meaningful Vision for...

Foundation Fighting Blindness ·

2025/02/24

MeiraGTx hopes to apply for marketing approval in the UK for the gene therapy.

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00:49:15

Eye on the Cure Podcast | Episode 81: Ricky Enger

Foundation Fighting Blindness ·

2025/02/20

February 21, 2025. Ricky Enger, the Director of Practical Help for Hadley, talks with host Ben Shaberman about her personal and professional journeys as someone born completely blind and the many assistive and accommodative technologies that are helpful to people with low vision. At Hadley, Ricky develops technology workshops and other community initiatives for older adults new to vision loss.

en

00:02:07

RD Fund Invests in Perceive Pharma for Development of...

Foundation Fighting Blindness ·

2025/02/18

Perceive Pharma is a spin out of Perceive Biotherapeutics.

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242 results

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