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PODCAST

Daily Value

Dr. William Wallace

Daily Value brings science out of the lab and into daily life. Hosted by Dr. William Wallace, each short, research-driven episode explores how nutrients, supplements, and metabolism influence how we think, move, and age. It’s evidence-based, concise, and designed to make you smarter about what fuels you.

health & fitness alternative health

All Episodes

10:06

Energy Drink Ingredient Linked to Cancer? The Taurine...

Daily Value ·

2025/05/30

In this episode of Daily Value, we look at the recent controversy surrounding taurine and its alleged role in accelerating leukemia (cancer) growth. We take a look at the science behind the recent sensationalist headlines generated by well-known mainstream media outlets, based on a study by the Wilmot Cancer Institute using animal and cell models, which suggested taurine might fuel leukemia progression. We clarify the context of this research, contrasting it with taurine's established safety ...

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12:45

B12: When Normal Isn't Enough

Daily Value ·

2025/05/28

In this episode of Daily Value, we look at recent research suggesting that the B12 levels we’ve always accepted as "normal" might silently be failing our brains. New data reveals that standard B12 thresholds may not adequately shield us from subtle neurological decline. Are current diagnostics overlooking hidden deficiencies? We go into how B12 truly supports your nervous system, the overlooked significance of active B12, and why traditional treatments might need reconsideration, particularly...

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8:24

The Nutrient Duo That Could Save Your Mind

Daily Value ·

2025/05/26

In this episode of Daily Value, we look into the synergistic relationship between two nutrient classes in supporting brain health and mitigating cognitive decline. Drawing on evidence from past clinical evidence suggesting these two nutrient classes work in tandem to support brain function and health. Discussion Points: -Homocysteine’s role in disrupting fatty acid incorporation into cell membranes and amyloid-beta clearance. -Findings from one study, where some 70-year-old participants exper...

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13:48

NAD Wars: NMN vs NR in the Aging Battle

Daily Value ·

2025/05/23

In this episode of Daily Value, we look inside the NAD+ wars - breaking down the science, the hype, and the controversy surrounding Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN). These two molecules have been promoted as keys to longevity, but the story is far more complex. We’ll look at the biochemistry of NAD+ metabolism, compare what the research really says about NR and NMN, and dig into the regulatory drama that’s shaped their (NMN’s) availability. Most importantly, we...

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20:06

The Vitamin D-ilemma: Are the New Guidelines Missing...

Daily Value ·

2025/05/21

Vitamin D recommendations in 1941 began this debate. Over the years, updated guidelines have continued to spark controversy and debate in the field of vitamin D research. In this episode of Daily Value, we look at the recent “Vitamin D-ilemma” reinvigorated by the Endocrine Society's updated 2024 guidelines. These new recommendations have dialed back routine testing and supplementation targets, igniting pushback from leading researchers who argue we might be overlooking significant health ben...

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11:34

Creatine Chronicles: Examining Safety and Dispelling...

Daily Value ·

2025/05/19

Debunking Myths: The safety and side effects of creatine supplementation. In this episode of Daily Value we look into the safety concerns surrounding creatine supplementation. Creatine, a well-researched dietary supplement known for its muscle-building and performance-enhancing benefits, has sparked numerous myths about its effects on kidneys, hair loss, and dehydration. We will evaluate recent studies and scientific evidence to address these myths. Topics include creatine's impact on water r...

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8:06

The Most Neuroprotective Compound You've Never Heard Of

Daily Value ·

2025/05/16

In this episode of Daily Value, we look at a forgotten compound found in common vegetables such as kale, spinach, and broccoli. Discovered in the 1930s and initially thought to be a vitamin (dubbed “Vitamin P”), this compound has recently demonstrated significant potential in neuroprotection. This compound may soon become an essential component in neuroprotective and longevity formulations. 00:00 Introduction to Brain Health Molecules 00:19 The Forgotten Flavonoid 01:08 Historical Background ...

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9:06

The Melatonin Mystery: Are Guidelines Wrong?

Daily Value ·

2025/02/19

In this episode of Daily Value, we look at newer research on melatonin that challenges conventional wisdom. A recent meta‐analysis questions current clinical guidelines on melatonin use for sleep, suggesting there may be a dual (Dose X Time effect) secret to optimizing its effects. We’ll break down the scientific clues behind optimal dosing, timing, and formulation, leaving you to wonder if you've been taking melatonin all wrong. Discussion Points: The clinical recommendations for melatonin m...

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9:59

B Vitamins & Neuropsychiatric Disorders—A Causal...

Daily Value ·

2025/02/17

In this episode of Daily Value, we look at the latest research on B vitamins and their in neuropsychiatric disorders. A newly published meta-analysis suggests a causal relationship between B vitamin deficiencies and neuropsychiatric disorders. We will break down the scientific findings on B6, B12, and folate, shedding light on their roles in conditions like Parkinson’s disease. Discussion Points: How recent genetic studies support a causal link between B vitamin deficiencies and mental health...

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10:57

The Forgotten Vitamin for Brain Health

Daily Value ·

2025/02/12

In today’s episode of Daily Value, we explore the possibly underappreciated role of vitamin K in brain health and neuroprotection. Recent research (doi: 10.3389/fnut.2024.1396707) reveals a connection between dietary vitamin K intake and reduced levels of neurofilament light chain, a potential biomarker for neurodegeneration, particularly in middle-aged and older adults. We’ll discuss how vitamin K supports neuronal function, what specific forms of vitamin K are most important, and how ...

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9:40

Beyond the Gym: Creatine’s Role in Women’s Health

Daily Value ·

2025/02/10

In this episode of Daily Value, we look at the emerging research on creatine supplementation in women’s health—beyond its well-established role in exercise performance. With evidence mounting on creatine’s impact across menstruation, pregnancy, postpartum recovery, and menopause, we discuss how it supports cognition, mood stabilization, and bone health throughout a woman’s lifespan. Discussion Points: Creatine & Hormonal Fluctuations: How estrogen and progesterone influence creatine uptak...

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14:59

B12 Deficiency: Uncovering the Silent Threat to...

Daily Value ·

2025/02/05

In today’s episode of Daily Value, we take a closer look at a commonly overlooked but essential nutrient: vitamin B12. Known as cobalamin, vitamin B12 deficiency can lead to severe neurological, hematological, and cognitive issues if left unchecked. We’ll cover the causes behind this growing issue, from dietary intake to malabsorption. Episode Talking Points: The role of B12 in nervous system function and red blood cell production.Causes of B12 deficiency, including dietary factors, autoimmun...

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8:12

How Male Alcohol Consumption Can Shape Offspring...

Daily Value ·

2025/02/03

In this episode of Daily Value, we look at how paternal alcohol consumption before conception could influence offspring health, longevity, and even accelerate aging. Referencing studies from Andrology (PMID: 38044754) and Aging and Disease (PMID: 39122451), we examine how sperm RNA modifications and mitochondrial dysfunction may persist long after alcohol cessation—potentially programming offspring for metabolic disorders, reduced NAD+ levels, and faster cellular aging. Discussion Points: Spe...

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9:05

Can Nutritional Psychiatry Offer New Solutions for...

Daily Value ·

2025/01/31

In this episode of Daily Value, we explore the potential of omega-3 fatty acids, particularly EPA and DHA, as an adjunctive therapy for reducing anxiety symptoms. A recent meta-analysis (PMID: 38890670) reviewed 23 randomized controlled trials involving over 2,100 participants, revealing that a certain amount of omega-3s per day can significantly reduce anxiety symptoms, especially when combined with traditional treatments like antidepressants.Talking points:Anxiety disorders: what are they a...

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8:29

Why 20 Grams of Olive Oil Could Be a Daily Health Habit

Daily Value ·

2025/01/29

In this episode of Daily Value, we look at how extra virgin olive oil and its polyphenols—including hydroxytyrosol—could impact your health and longevity. Referencing evidence from the Moli-Sani Study and other meta-analyses (PMID: 38704428), we uncover how these bioactives are suggested to reduce risks for cancer, cardiovascular disease, and all-cause mortality.Discussion Points:Bioactive Compounds: How hydroxytyrosol prevents LDL oxidation and reduces inflammation, key mechanisms for cardio...

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9:02

Brewed for Benefits: Coffee’s Impact on Fat and Muscle

Daily Value ·

2025/01/27

In this episode of Daily Value, we look at how the roasting style of coffee—light versus regular—might influence body composition. Examining evidence from a recent randomized controlled trial published in Nutrients (PMID: 39275165). Could your choice of coffee enhance fat loss and muscle mass?Discussion Points:Roasting and Polyphenols: How lightly roasted coffee, with higher chlorogenic acid content, outperformed regular roasts in reducing body fat (-1.4% vs. -1.0%) and increasing muscle mass...

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11:17

The Surprising Gut Health Benefits of B-Vitamins

Daily Value ·

2025/01/24

In this episode of Daily Value, we explore the recent findings on the role of B-group vitamins as potential prebiotic candidates and their effects on the human gut microbiome. The discussion is centered around some of the latest research, which highlights how these essential vitamins, traditionally known for their metabolic roles, are now being recognized for their ability to modulate the gut microbiome and how different bacterial species may also play key roles as B-vitamin Producers.Discuss...

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9:55

Your DNA on Caffeine

Daily Value ·

2025/01/22

In this episode of Daily Value, we look at the relationship between genetics, habitual caffeine intake, and cognitive performance, using insights from a recent study (PMID: 39648354) in the Journal of Psychopharmacology. Whether you’re a "fast" or "slow" caffeine metabolizer could significantly influence how caffeine impacts your brain.Discussion Points:Gene-Caffeine Interactions: how variants in CYP1A2 and ADORA2A genes modulate caffeine metabolism and sensitivity, leading to differential ef...

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8:19

Can Green Tea Preserve the Brain Better than Coffee?

Daily Value ·

2025/01/20

Does green tea protect the aging brain better than coffee? In this episode of Daily Value, we look at the evidence behind green tea's impact on brain aging, focusing on cerebral white matter lesions, Alzheimer’s risk, and brain atrophy. Drawing on studies like Shibata et al.'s recent publication in Science of Food (PMID: 39774601), we discuss how a certain threshold of green tea, but not coffee is associated with less white matter lesions in aged individuals.Discussion Points:MRI findin...

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8:13

Building Brains: B12 During Pregnancy & Childhood IQ

Daily Value ·

2025/01/17

In this episode of Daily Value, we look at the role of maternal Vitamin B12 intake during pregnancy and its impact on a child’s IQ. Drawing on findings from the ELSPAC study (PMID: 39674678), we discuss how Vitamin B12 supports critical neurodevelopmental processes and how deficiency may impact verbal IQ.Discussion Points:The role of Vitamin B12 in one-carbon metabolism, axon myelination, and DNA methylation, and their importance for fetal brain development.Findings from the ELSPAC study, whe...

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73 results

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