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PODCAST

Longevity by Design

Gil Blander PhD

Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan.In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scientific

health & fitness medicine

All Episodes

111:36

Precision Longevity Medicine with Dr. David Barzilai

Longevity by Design ·

2025/02/05

Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity physician and founder of Barzilai Longevity Consulting, to explore the science of extending healthspan through precision and innovation. Dr. Barzilai shares his journey into biogerontology and longevity science, unpacking key concepts like the hallmarks of aging, the potential of lifestyle inter...

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56:24

How Can a Nutrition AI Platform Help Us Live...

Longevity by Design ·

2025/01/22

On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition coaching platform. Dmitriy discusses his career path from astrophysics to the world of nutrition tracking. He explains how his company seeks to make healthy eating more accessible. Passio aims to achieve this through user-friendly technology like food scanning, voice logging, and personalized AI coaching.Dmitriy believes this technology will revolutioni...

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53:55

The Path to a 1,000-Year Lifespan with Dr. Aubrey de...

Longevity by Design ·

2025/01/08

In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey shares his work identifying and addressing the seven major categories of aging-related diseases. He discusses how targeted damage repair offers a promising alternative to traditional methods to slow aging, providing a path to longer, healthier lives.The conversation delves into the hallmarks of ...

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37:09

Dietary Changes to Reduce the Risk of Prostate Cancer...

Longevity by Design ·

2024/12/18

On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate cancer and the impact of diet on disease progression. John shares his personal connection to this disease and why he’s dedicated his research to understanding dietary interventions.John explains that prostate cancer is often slow-growing, with most men experiencing decades between early mutations and noticeable tumor growth. He stresses the importance of early detection through regular checkup...

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83:16

Unlocking Longevity: Dr. Jens Juul Holst on GLP-1’s...

Longevity by Design ·

2024/12/04

In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes.The conversation explores how GLP-1 receptor agonists, have e...

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47:57

Food Fermentation and Its Effect on Healthspan with...

Longevity by Design ·

2024/11/20

Episode highlights:Introduction: 00:00:00Why have you decided to become a scientist: 00:02:30What is fermentation: 00:07:45What microbes are involved in fermentation: 00:08:40How those microbes get into the fermented food: 00:09:35When the Humankind started to utilize fermentation: 00:11:20What is the difference between Probiotics and Live Cultures: 00:15:15What are the benefits of fermented food consumption: 00:17:43What foods are produced through lactic acid fermentation, and what are the b...

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61:46

Taste and Smell Preferences and Their Impact on...

Longevity by Design ·

2024/11/06

On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, personal preferences, and long-term health. Yanina's research shows our food environment significantly shapes cravings. This exposure starts as early as the womb, impacting future preferences.Yanina explains that bariatric surgery and GLP-1 medications are powerful tools for weight management. However,...

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22:39

Ask Me Anything (AMA): Nutrition Deep Dive with Dr....

Longevity by Design ·

2024/10/23

In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive Solution. After years of research and development, they share the journey of creating a food recognition platform that helps users track their food intake in real time. The goal is to provide users with personalized recommendations for better health and nutrition based on their dietary habits.Dr...

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46:23

Unlocking the Secrets of Longevity with Dr. David...

Longevity by Design ·

2024/10/09

In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse this process.He explains how lifestyle factors, such as diet and exercise, can greatly impact our longevity, and highlights the importance of regu...

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51:26

The Impact of Artificial Intelligence, Machine...

Longevity by Design ·

2024/09/25

In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness.Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how InsideTracker has developed a specialized LLM called Ask InsideTracker. This tool allows users to interact with a vast knowledge base of health and...

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68:34

The Surprising Link Between Space Travel and Aging...

Longevity by Design ·

2024/09/11

On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade inflammation can accelerate the aging process. Discover how David's team developed a new inflammatory age test, soon to be available from his company

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62:33

Improvements in Blood and Fitness Tracker Biomarkers...

Longevity by Design ·

2024/08/28

In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computational biology, emphasizing the importance of integrating large-scale biological data to develop high-resolution molecular models of diseases.Nimisha ...

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74:00

Parkinson's and Alzheimer's: The Gut-Brain Connection...

Longevity by Design ·

2024/08/15

In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches.Dr. And...

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75:29

The impact of ketones on performance and aging with...

Longevity by Design ·

2024/07/31

In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging.Dr. Stubbs discusses the science behind ketones, explaining how they serve as an alternative fuel for the brain and body, particularly during periods of low carbohydrate int...

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72:48

The impact of ultra-processed foods and fructose on...

Longevity by Design ·

2024/07/10

In this episode of Longevity by Design, host Dr. Gil Blander talks with Dr. Robert Lustig, an emeritus professor of pediatrics at UCSF and a renowned neuroendocrinologist. Dr. Lustig dives into the impact of ultra-processed foods and fructose on metabolism, emphasizing how these contribute to obesity and metabolic diseases. He also discusses his journey from academia to public health advocacy, aiming to reform the food industry and reduce chronic diseases.Episode highlights:Introduction: 00:0...

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29:55

Ask Me Anything (AMA): Optimizing Health & Longevity...

Longevity by Design ·

2024/06/26

In this Longevity by Design Ask Me Anything (AMA) episode with Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, the focus is on user questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health improvement. He explains how this model encourages users to maintain their health optimization practices consistently over time, enhancing the overall ...

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48:50

Understanding Aging to Extend Healthspan and...

Longevity by Design ·

2024/06/12

In this episode of Longevity by Design, hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander sit down with Dr. Gordon Lithgow, a Professor and Vice President for Academic Affairs at the Buck Institute for Research on Aging. Dr. Lithgow's research focuses on understanding the mechanisms of aging and identifying genes and small molecules that can prolong lifespan. With a background in genetics from the University of Glasgow and extensive experience in biotechnology and aging research, Dr. Lit...

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65:58

The Impact of Exercise & Nutrition on Muscle,...

Longevity by Design ·

2024/05/15

In this episode of Longevity By Design, co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander welcome renowned professor Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. During this episode, he shares his expertise on the critical role of exercise and nutrition for musculoskeletal health, longevity, and improving quality...

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78:22

The Impact of DNA Damage & Lifestyle on Aging &...

Longevity by Design ·

2024/05/01

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72:14

The Effects of Cellular Senescence and Senolytics on...

Longevity by Design ·

2024/04/17

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