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PODCAST

Stimulating Brains

Andreas Horn interviews experts in the field of deep brain stimulation, noninvasive neuromodulation, functional brain imaging and neuroanatomy. Join us on our quest to interact with the human brain and thank you for your interest in science! Andreas Horn, M.D., Ph.D., directs the institute for network stimulation and is a professor for computational neurology at University Cologne.

science natural sciences

All Episodes

02:11:15

#53: Mark Hallett – Putting Transcranial Magnetic...

Stimulating Brains ·

2024/04/30

Dr. Mark Hallett is arguably the person that put transcranial magnetic stimulation (TMS) on the map. Besides that, he is an authority in the field of movement disorders and motor control, with specific focus – spread throughout the years – on Parkinson's Disease, dystonia and functional movement disorders. In our conversation, Dr. Hallett shares anecdotes from the early time of the TMS field, his large number of mentors and even larger number of mentees, how he was able to treat the pianist Leon

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01:14:06

#52: Amaza Reitmeier – Changing lives at scale with...

Stimulating Brains ·

2024/04/18

In our ongoing exploration of the DBS ecosystem through the lens of key industry leaders, below is our conversaion with Amaza Reitmeier who is the Vice President and General Manager of Brain Modulation at Medtronic. We learn differences between life in academia and industry, with a key potential of industry work to get the ability to make change at scale.In this episode, we discuss what the future of brain modulation may offer, with some aspirational commentary on several potential opportunities

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01:45:40

#51: Alfonso Fasano & Benjamin Stecher – A Unique...

Stimulating Brains ·

2024/04/05

In this very special episode, we are thrilled to welcome back Ben Stecher, marking his remarkable third appearance on StimBrains (you can find him previously featured on episodes #12 and #14). Today’s discussion takes a profound turn as we delve into the unique collaboration between Ben and his neurologist Dr. Alfanso Fasano, who is a Professor in the Department of Medicine (Division of Neurology) at the University of Toronto.Together, they’ve co-authored ‘Reprogramming The Brain‘, a book that

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01:16:06

#50: Andreas Horn – Toward Connectomic Deep Brain...

Stimulating Brains ·

2024/03/19

When I interviewed Marwan Hariz for episode #4, he wrote in an email: "When you finish the series and all interviews, please let me know because then I should interview you as the Grand Finale of this series…". Throughout the recordings, I heard similar remarks from other guests but also, increasingly, from listeners of the show. After Nico Dosenbach suggested the same in #39, Mike Fox called me and offered to interview me for a round episode of the podcast. With this episode, Stimulating

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01:46:20

#49: Dora Hermes & Kai Miller – Discovering the...

Stimulating Brains ·

2024/03/16

Dora Hermes and Kai Miller are associate professors at Mayo Clinic, where they have become a powerhouse on neuroscience, due to their strong collaboration and work in neural signal processing and analysis. Dora has a mathematics background, while Kai studied physics, including a PhD in physics, before becoming a functional neurosurgeon. Last year, both of them last authored a paper each at Nature Neuroscience, each with remarkable and groundbreaking findings about pretty different topics. The first

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01:25:12

#48: Binith Cheeran: From Clinical Neurology to...

Stimulating Brains ·

2024/03/06

In our ongoing exploration of the DBS ecosystem throughout the podcast, we've engaged with leading voices in academia, clinical practice, and the patient community, each offering invaluable perspectives on the transformative impact of DBS. Yet, the journey from laboratory to bedside is a collaborative endeavor that requires another critical player: the industry. The symbiosis between innovative scientific research and robust industry support is crucial for the successful transition of

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02:14:41

#47: Marwan Hariz & Joachim Krauss – Toward a third...

Stimulating Brains ·

2024/02/23

Marwan Hariz and Joachim Krauss need no introduction. First, because they are famous, and second, because they have been on the show, before. In fact, Marwan Hariz is the first to have been on the podcast three times, first, as an early adopter and trustee in episode 3, second, together with Joachim Krauss and Christian Moll in episode 33, and now again with Joachim in the present episode. I met Joachim in Grenoble at a meeting celebrating the 30th year anniversary of STN-DBS. He mentioned that the

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01:30:13

#46: Todd Langevin – Establishing Deep Brain...

Stimulating Brains ·

2024/02/16

So far, in the podcast, I have been interviewing key opinion leaders from academia and clinical practice, and sometimes individual patients that graciously shared their insights after undergoing DBS. However, beyond patients and clinicians, there is a third component necessary for DBS to be successful, which are our partners in the industry. Without great industry leadership, it is hard if impossible to translate scientific findings into clinical practice. For instance, when the Grenoble team

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02:07:47

#45: Mac Shine and Paul Cisek - Exploring the...

Stimulating Brains ·

2023/12/07

In this special episode of Stimulating Brains, we dive deep into the intricacies of the human brain with two esteemed guests, Mac Shine from Sydney University and Paul Cisek from the University of Montreal. Building upon our earlier conversation with Mac in episode 9, this episode sees these brilliant minds sharing their insights on the basal ganglia, the role of dopamine, and the fascinating interplay between various brain regions. In addition, we explore the modulation of the thalamus by the basal

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01:58:43

#44 Jennifer Thomas & Michael Stanley - The creative...

Stimulating Brains ·

2023/11/24

In this conversation with Jennifer ('Niffy') Thomas and Dr. Michael Stanley, we talk about how Niffy became an artist after undergoing DBS surgery to treat her early onset Parkinson's Disease. Dr. Michael Stanley is a cognitive neurologist at the Brigham & Women's Hospital and has special interest in art and the brain: He studies how lesions or other neurological conditions can lead to cessation of artistic behavior or how they can change the artistic style of artists. When he

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01:28:45

#43 Vanessa Milanese - Bridging Anatomy and...

Stimulating Brains ·

2023/10/19

In this conversation with Dr. Vanessa Milanese, we cover the importance of anatomy in neurosurgery and explore her intriguing work in both fields – and how they cross-informed one another. Vanessa is a functional neurosurgeon at A Beneficencia Portuguesa Hospital in São Paulo, Brazil and holds an adjunct assistant professorship of neurosurgery at Mayo Clinic in Jacksonville, Florida. We talk about her stellar work in combining her neurosurgical activity with anatomical work – which involves

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01:14:45

#42: Kullervo Hynynen – A conversation with the...

Stimulating Brains ·

2023/10/13

In this episode, we sit down with Dr. Kullervo Hynynen, a key figure in biomedical ultrasound and image-guided therapeutics. Starting from his academic roots at the University of Aberdeen to his current roles at the Sunnybrook Research Institute and the University of Toronto, Dr. Hynynen has played an instrumental role in advancing medical imaging.He has been at the forefront of investigating the use of focused ultrasound for various medical procedures such as non-invasive surgery, vascular

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02:00:58

#41: Christelle Baunez – The role of the subthalamic...

Stimulating Brains ·

2023/10/07

In this intriguing dialogue with Dr. Christelle Baunez, a neurobiologist at Aix-Marseille University, we discuss a mysterious and small structure, the subthalamic nucleus. Christelle is known as the STN woman in France, due to her dedication to study this structure over the years. Christelle is a pioneer in the side effects related to STN stimulation in Parkinson Disease patients. Now, she is working towards understanding how STN stimulation can help people with addiction. We cover, with an

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01:55:20

#40: Casey Halpern – Novel indications and approaches...

Stimulating Brains ·

2023/09/22

In this engaging conversation with Casey Halpern, a functional neurosurgeon at Penn Medicine. Casey is a pioneer in both deep brain stimulation and focused ultrasound and with his lab has recently had some fantastic breakthroughs, especially, but not exclusively in the field of loss-of-control eating in severe obesity. We cover a lot of ground from optogenetics at Stanford, basic science research about the nucleus accumbens and translation of findings into patients, serendipitous discoveries in

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02:06:32

#39: Nico Dosenbach – A BOLD Challenge to Penfield’s...

Stimulating Brains ·

2023/09/18

In this engaging conversation with Dr. Nico Dosenbach, a clinician-scientist at Washington University, we dive into his personal journey from the Black Forest in Germany to his adventures in the US. Nico generously shared insights into his educational and career path, recounting his experiences studying biochemistry in New York City, making the decision to pursue an MD/PhD, and eventually specializing in pediatric neurology. The conversation delved into his early days as a researcher at Washington

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00:50:59

#38: Espen Dietrichs – about Carl Sem-Jacobsen, the...

Stimulating Brains ·

2023/09/10

In this conversation with Espen Dietrichs, we talk about the work of Carl Wilhelm Sem-Jacobsen, who almost certainly applied deep brain stimulation to the subthalamic nucleus chronically over weeks in 1958. Notably, this was ~40 years before the application of subthalamic DBS in Grenoble by the team of Alim Louis Benabid & Pierre Pollak (episode 4) following the pioneering animal work by Hagai Bergman (episode 17) and Abdelhamid Benazzouz who had demonstrated lesioning and DBS to the subthalamic

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01:50:41

#37: Jon Nelson – DBS for Depression saved my life:...

Stimulating Brains ·

2023/08/17

In this compelling episode we delve into the inspiring story of Jon Nelson, a remarkable individual who has braved the depths of mental illness and emerged as a beacon of resilience and hope. In a heartfelt conversation with Jon, he shares his lived experience with DBS device as a transformative treatment for mental illness. Against the backdrop of prevailing stigma surrounding mental health, Jon's journey unfolds as he not only navigates the challenges of his condition but also becomes an

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01:43:39

#36: Béchir Jarraya & Jordy Tasserie – Unlocking...

Stimulating Brains ·

2023/08/06

In this episode, we delve into the groundbreaking work of the Neuromodulation Lab at the NeuroSpin center, led by Dr. Béchir Jarraya. The lab’s mission is to evaluate brain modulation using pharmacological agents and electrical neurostimulation. Combining functional MRI with new neuromodulation techniques, they train awake macaques, with a unique mock-MRI process, to study consciousness-related domains. Their activities encompass MRI, electrophysiology, and 3-photon imaging to unlock the mysteries

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01:13:04

#35: Mark Richardson – Surfing the Frontiers of...

Stimulating Brains ·

2023/06/19

In this episode, we interviewed Dr. Mark Richardson, an expert in functional neurosurgery and the Director of the Brain Modulation Lab at MGH Neurosurgery. He shared insights into his career and the lab's focus on improving surgical treatments for epilepsy, movement disorders, and psychiatric diseases through a systems neuroscience approach. We discussed closed-loop deep brain stimulation in epilepsy, incision-less approaches like FUS and LITT, and the role of different nuclei in generalized

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01:11:21

#34: Charles Jennings – From Graduate School to...

Stimulating Brains ·

2023/05/09

We had the privilege of interviewing Dr. Charles Jennings, an accomplished scientist and leader in the field of neuroscience. As the Executive Director of the Program for Interdisciplinary Neuroscience and the Ann Romney Center for Neurologic Disease, Dr. Jennings oversees a vast network of researchers and clinicians who are dedicated to advancing our understanding of the brain and developing new treatments for neurological disorders. Dr. Jennings’ work is especially noteworthy for its collaborative

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