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PODCAST

Stimulating Brains

Andreas Horn interviews experts in the field of deep brain stimulation, noninvasive neuromodulation, functional brain imaging and neuroanatomy. Join us on our quest to interact with the human brain and thank you for your interest in science! Andreas Horn, M.D., Ph.D., directs the institute for network stimulation and is a professor for computational neurology at University Cologne.

science natural sciences

All Episodes

01:44:49

#73: Eyal Zadicario – Beyond the Scalpel: Towards an...

Stimulating Brains ·

2025/11/10

In this episode of Stimulating Brains, we sit down with Dr. Eyal Zadicario, Chief Operating Officer at Insightec, to explore the remarkable evolution of focused ultrasound – from its experimental origins to its transformative role in functional neurosurgery today.Dr. Zadicario shares insights from over two decades at the forefront of innovation, reflecting on the challenges of translating breakthroughs from academia to industry, designing clinician-friendly systems that prioritize the patient

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01:22:41

#72: John Rolston — Closed-Loop Stimulation, Seizure...

Stimulating Brains ·

2025/08/01

Today, we had the privilege of speaking with Dr. John Rolston, a leading voice at the intersection of neurosurgery, epilepsy, and brain stimulation.Dr. Rolston is an Associate Professor of Neurosurgery at Harvard Medical School and the Director of Epilepsy Surgery at Brigham and Women’s Hospital. His pioneering work bridges clinical neurosurgery and computational neuroscience, focusing on how electrical stimulation can modulate dysfunctional brain networks to treat epilepsy, movement disorders, and

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02:01:33

#71: Harold Sackeim - The founding editor of Brain...

Stimulating Brains ·

2025/04/24

Today we had the privilege of speaking with a true pioneer in the field of neuropsychiatry and brain stimulation— Dr. Harold Sackeim.Dr. Sackeim is perhaps best known for his extensive research on electroconvulsive therapy (ECT), but his contributions span a wide range of topics from treatment-resistant depression to the placebo effect in neurostimulation. As a founding figure in modern ECT research, he has played a central role in shaping both the science and the clinical practice of brain

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01:50:08

#70: Rees Cosgrove – When Neurosurgery Chooses You:...

Stimulating Brains ·

2025/04/22

In this episode, we journey through the remarkable career of Dr. Rees Cosgrove—a trailblazer in functional neurosurgery, Director of Epilepsy and Functional Neurosurgery at Brigham and Women’s Hospital, and Professor of Neurosurgery at Harvard Medical School.Dr. Cosgrove reflects on his formative years training in the very halls that were roamed by legends such as Wilder Penfield at the Montreal Neurological Institute, and takes us through pivotal chapters of his career leading programs at

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01:46:48

#69: Terrence Sanger – Pushing Boundaries in...

Stimulating Brains ·

2025/03/27

In this episode we will dive deep into the minds of leading researchers and clinicians in the field of neuromodulation. Today, we are thrilled to have Dr. Terry Sanger with us.Dr. Sanger is a renowned pediatric neurologist, engineer, and Chief Scientific Officer at CHOC, where he focuses on improving the lives of children with movement disorders—especially dystonia. He’s well known for combining deep computational approaches with cutting-edge neuromodulation techniques.In this episode, we’ll uncover

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01:41:05

#68: Todd Herrington – The Future of Neuromodulation:...

Stimulating Brains ·

2025/03/18

In this episode, we have the privilege of speaking with Dr. Todd Herrington, a leading neurologist and director of the Deep Brain Stimulation (DBS) program at Massachusetts General Hospital. Dr. Herrington specializes in movement disorders such as Parkinson’s disease, tremor, and dystonia, and his research focuses on the motor, cognitive, and psychiatric effects of DBS, leveraging intraoperative and noninvasive neurophysiology and neuroimaging to advance neuromodulation therapies.Today, we’ll

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01:25:10

#67: Jonathan Downar – TMS for Depression: Towards a...

Stimulating Brains ·

2025/03/03

In this episode, we’re joined by Dr. Jonathan Downar, a psychiatrist and neuroscientist based in Toronto, renowned for his pioneering research in transcranial magnetic stimulation (TMS) for depression. You may recognize him from his landmark work on the Three-D Trial, which helped establish intermittent theta-burst stimulation (iTBS) as a rapid and effective alternative to standard repetitive TMS.Recently, Jonathan has been pushing the boundaries of TMS with accelerated treatment protocols,

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01:26:54

#66: Roxanne Lofredi – Striatal recordings and the...

Stimulating Brains ·

2025/01/03

In this episode, we have a privilege to talk with Dr. Roxanne Lofredi, a prominent researcher investigating movement disorders and deep brain stimulation (DBS). Dr. Lofredi is based at Charité – Universitätsmedizin Berlin and is widely recognized for her groundbreaking contributions to understanding how basal ganglia networks drive motor symptoms in conditions such as dystonia and Parkinson’s disease.Today, we’ll explore two fascinating studies led by Dr. Lofredi. The first focuses on how

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01:15:08

#65: Jim McNasby - Transforming Lives with DBS and...

Stimulating Brains ·

2024/12/23

In this episode of Stimulating Brains, we're thrilled to have Jim McNasby join us. Jim is a deep brain stimulation (DBS) patient and the Chief Counsel at the Michael J. Fox Foundation. Jim has an inspiring story, not just as a DBS patient but also as a legal professional working at the forefront of Parkinson’s research advocacy. We’ll dive into his personal experience with DBS—how it has shaped his life since his diagnosis in 2000 and his surgery in 2019—and explore his crucial role at the Michael

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01:33:28

#64: Balint Varkuti – Making Use of Side-Effects:...

Stimulating Brains ·

2024/12/13

Today, we have the pleasure of speaking with Dr. Bálint Várkuti, a distinguished expert in the field of neuromodulation. Dr. Várkuti is the founder and CEO of CereGate, a pioneering company developing brain-computer interface technologies—referred to as computer-brain interface technologies—that aim to enhance neuromodulation therapies.Before founding CereGate, Dr. Várkuti made significant contributions to image-guided DBS programming solutions at Brainlab. With over a decade of experience in

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01:53:19

#63: Mark McAuley & Susan Boehnke – Patient-led...

Stimulating Brains ·

2024/11/20

In this episode, we have the pleasure of hosting Mark McAuley, a deep brain stimulation (DBS) patient and the CEO of Astronomy Australia Limited, and Dr. Susan Boehnke, an Associate Professor at Queen’s University in Canada and director of the Neurotech Microcredential Program and the Neurotech Discovery Lab. Together, they've been part of remarkable efforts that not only focus on the practical and ethical aspects of neurotechnology but also engage students in real-time research.Mark brings over

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01:49:02

#62: Daniela Popa & Clement Lena – Unlocking the...

Stimulating Brains ·

2024/11/11

In today’s episode, we dive deep into two groundbreaking studies led by Daniela and Clément. We explore their 2022 Nature Communications paper on using cerebellar stimulation to alleviate levodopa-induced dyskinesias in Parkinson’s disease and discuss their 2023 paper uncovering the cerebellum’s role in regulating fear extinction through its connections with the thalamo-prefrontal cortex pathway. Along the way, we discuss how these discoveries may open up exciting new possibilities for treating both

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01:12:17

#61: Shan Siddiqi – Bringing Human Brain Connectomics...

Stimulating Brains ·

2024/11/05

In this episode, I was able to talk to Dr. Shan Siddiqi, who is an Assistant Professor of Psychiatry at Harvard Medical School and a researcher at the Center for Brain Circuit Therapeutics at Brigham and Women’s Hospital, where he and his lab focuses on brain circuit therapeutics. Shan’s work bridges the gap between neuroimaging and causality, exploring the mechanisms of brain stimulation and lesions in neuropsychiatric disorders such as depression and post-traumatic stress disorder (PTSD). He’s

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00:54:13

#60: Dr. Nanthia Suthana – Pushing Boundaries: Memory...

Stimulating Brains ·

2024/11/01

In this episode, we’re joined by Dr. Suthana, a leading neuroscientist from UCLA's David Geffen School of Medicine and the Jane & Terry Semel Institute for Neuroscience & Human Behavior. Dr. Suthana’s career sits at the intersection of neuroscience, neural technology, and engineering, focusing on memory disorders and innovative brain technologies.We explore her groundbreaking research on memory enhancement through deep brain stimulation (DBS), focusing on a study where stimulation of the

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01:34:54

#59: Milad Girgis – 25 Years of Progress: Evolution...

Stimulating Brains ·

2024/08/14

As a fourth installment of this podcast into key industry leaders in neuromodulation, this is our conversation with Milad Girgis, who is the VP and General Manager of the Brain franchise at Boston Scientific.Milad has dedicated over 25 years to the Medical Device Industry, with two decades at Boston Scientific. Before diving into his impressive tenure at Boston Scientific, we explore the earlier phases of his career and identify key turning points that shaped his professional journey. Milad

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01:29:12

#58: Ali Rezai – Long lasting Effects of Focused...

Stimulating Brains ·

2024/08/02

In this episode, we have an insightful conversation with Dr. Ali Rezai, who is the Associate Dean of Neuroscience at West Virginia University (WVU) and Executive Chair and Director of its Rockefeller Neuroscience Institute (RNI). We take a deeper dive into Dr. Rezai’s career, which features his notable achievement of performing 900 neurostimulator implants by 2006.We highlight Dr. Rezai’s involvement in deep brain stimulation (DBS) and focused ultrasound (FUS), particularly in treating severe

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01:30:21

#57: Mallory Hacker & David Charles – Could DBS be...

Stimulating Brains ·

2024/07/26

Mallory Hacker is an Assistant Professor for Neurology in the team of David Charles, who is Professor of Neurology, Vice-Chair for Business Development and Strategy, as well as the Medical Director for Telehealth at Vanderbilt University Medical Center in Nashville, Tennessee. In 2006, after a stay at Alim Louis Benabids team in Grenoble, France, David started to investigate the question of whether subthalamic DBS could lead to slowing of motor progression in patients with early stages of

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02:00:04

#56: Harith Akram – Connectomic DBS, Sweetspots and...

Stimulating Brains ·

2024/07/09

Harith Akram is the consultant neurosurgeon at the National Hospital for Neurology and Neurosurgery (UCLH) and the Unit of Functional Neurosurgery (UCL) at Queen Square. We discuss Dr. Akram's hobbies beyond the lab and OR and delve into his fascinating journey which culminated in him training in the UK, with many stops along the way.Harith shares insights into his illustrious career, highlighting the key mentors who shaped his path, including Drs. Marwan Hariz and Ludvic Zrinzo. With many

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01:37:35

#55: Jens Volkmann – Image Guidance, Disease...

Stimulating Brains ·

2024/07/03

Jens Volkmann is a Professor and the chair of Neurology at University Hospital Würzburg in Germany and one of the key DBS experts in the field. I have intensely collaborated with Jens and his team and he has been a mentor for me since a long time. In fact, in this conversation, Jens reminded me of exactly when we first met, during a summer school in cortona, italy, where I was fortunate enough to listen to fantastic talks by exciting faculty including Jens about the future of Deep Brain Stimulation

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01:24:08

#54: Phil Starr – Using cortical signals to guide...

Stimulating Brains ·

2024/06/23

Phil Starr is a Professor of Neurological Surgery at University of California, San Francisco and a developer of implantable brain devices. At UCSF, he co-directs a multidisciplinary neurology/neurosurgery movement disorders clinic together with Dr. Jill Ostrem. I’ve been a long-time admirer of Phil’s work and in this conversation we blaze through quite a few of his numerous publications. One key breakthrough and invention of Phils work has been to include Ecog recordings – both intraoperatively

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73 results

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