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PODCAST

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade,Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -has redefined what’s possible for the human mind and body. After more than a thousand episodes ofBulletproof Radio, he’s taking it to the next level withThe Human Upgrade™- a masterclass inbiohacking, longevity, and performance optimization.Each episode explorescutting-edge science, advanced technology, and proven biohacksto help youupgrade your energy, focus, metabolism, and resilience.You’ll

health & fitness self-improvement

All Episodes

00:12:42

I Lost 100 Pounds By Fasting Like THIS (The Missing...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/28

This video reveals the hidden mistake most people make when fasting that causes muscle loss instead of fat loss.

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00:12:28

Biohacking News Weekly Update : 1388

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/26

This weekly rundown breaks down how drug pricing policy, smarter fasting strategies, cocoa bioactives, organ-specific aging clocks, and skin-focused longevity tech are reshaping what actually works in modern biohacking and prevention.

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01:12:51

How to Get and Stay Sober in 2026 (The Biohacker’s...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/25

This episode explores how addiction really works beneath the surface, and shows how long term sobriety is built by rewiring biology, nervous system patterns, and identity rather than relying on willpower alone.

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01:02:30

What it takes to be “Young Forever!” | Mark Hyman : 1385

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/23

This episode breaks down how aging is driven by modifiable biological systems like insulin signaling, mTOR, mitochondria, and inflammation, and shows how targeted biohacking, nutrition, and functional medicine can slow or even reverse biological age.

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00:13:06

I Tried $50 Brain Boosting Powder : 1384

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/21

This episode uncovers why muscle tone and cognitive power decline early in adulthood and shows how a simple, science-backed supplement can restore ATP production, sharpen memory, improve stress and sleep resilience, and slow age-related deterioration when used correctly.

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00:11:28

Biohacking News Weekly Update : 1383

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/19

This episode breaks down five cutting-edge findings in supplements, cardiac diagnostics, detox science, psychedelics and metabolic control, and mitochondrial aging to reveal how emerging research can translate into practical upgrades for your health and longevity.

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00:57:44

The Science of Erotic Altered States | Biohacking Sex...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/18

This episode explores how intimacy, desire, and erotic states function as powerful tools for healing, nervous system regulation, and personal transformation.You’lllearn why certain forms of conscious erotic play create genuine altered states of consciousness, not through substances or external compounds, but through the body’s own internal chemistry. This conversationreframessexuality as a core aspect of health, performance, and emotional resilience rather than somethingseparatefrom

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01:03:37

Biohacking Fertility for Men and Women at Any Age : 1381

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/16

This episode lays out the blueprint for having healthier children later in life by treatingpreconceptionas the most important window for human health.You’lllearn why fertility is not just about gettingpregnant, butabout building the biological foundation that shapes a child’s brain development, metabolism, immune function, andlong termresilience. This conversationreframesinfertility as a meaningful signal to pause, repair, and prepare, instead of something to override or rush past.Watch

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00:16:13

Your Brain Has A Sleep Switch (Do THIS To Turn It On)...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/14

Try TrueDark Glasses: https://truedark.com/?coupon-code=DAVETUBE&sc-page=shopKill your zombie cells with: http://www.qualialife.com/davenad Your brain has a built-in switch that controls deep sleep but for most people, it’s turned off. In this video, Dave Asprey exposes the hidden factors blocking your deep sleep. He shows how small changes to posture, meal timing, and lighting can reactivate your brain’s sleep control center so you sleep deeper, recover faster, and wake up refreshed,

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00:52:20

The One Thing Everyone Thinks They Can’t Afford…...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/12

This episode shows how entrepreneur Jonathan Swanson uses world class delegation and human plus AI support to reclaim time, reduce stress, and create the personal leverage needed for better health, clearer thinking, and a more ambitious life.

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00:47:34

How To Sculpt a Perfect Jawline WITHOUT Surgery : 1378

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/11

Your jaw influences far more than your face. This episode shows you how jaw strength shapes cognition, posture, airway health, sleep, metabolism, and overall human performance. You will learn how targeted jaw training increases cranial blood flow, improves neuromuscular coordination, strengthens airway stability, and stimulates facial muscles that modern diets no longer challenge.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave

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00:52:07

I Tried At-Home Ultrasound for My Brain : 1377

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/09

Most people stay locked in a constant sympathetic state without realizing it, which drains focus, sleep quality, emotional balance, and long-term resilience. This episode gives you a science backed path to retrain your nervous system, improve heart rate variability, and shift out of stress on command using focused ultrasound technology that targets the vagus nerve.Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPRHost Dave Asprey talks with

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00:12:08

What If You Stop Eating For 72 Hours? : 1375

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/07

Dave Asprey breaks down what really happens during a 72-hour fast, showing how deep cellular repair, autophagy, and mitochondrial rejuvenation activate only in the later stages of fasting and how to prepare, fast, and refeed safely for the strongest anti-aging results.

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00:57:18

The Real Reason Your Face Is Aging So Fast : 1376

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/05

Vitamin C, copper peptides, and glutathione behave very differently once you understand how skin absorbs nutrients at the cellular level. This episode shows you how to target collagen production, strengthen mitochondria, improve detox capacity, and upgrade skin density with pharmaceutical grade delivery systems that outperform conventional skincare. You learn why most topical antioxidants never reach their intended targets, how intracellular copper changes longevity pathways, why

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01:01:16

Feel 70 Percent Better… With Grapes? | Biohacking...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/04

If you care about longevity, mitochondria, cardiovascular health, or feeling sharper every day, this episode gives you a clear look at the breakthrough technology that could reshape how supplements are made. Host Dave Asprey talks with Ilan Sobel, CEO of BioHarvest Sciences, about a new way to produce plant compounds at industrial scale without ever growing the plant. Their Botanical Synthesis platform creates highly pure, clinically validated molecules that support blood flow, brain

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00:55:57

The Machine That Flicks on Your Brain in 30 Seconds |...

The Human Upgrade: Biohacking for Longevity &... ·

2025/12/02

This episode explores how Raffaele Gianfrancesco uses vibroacoustics, flickering light, and harmonic frequency technology to rapidly shift brain states, release stored trauma, and create deep coherence in the mind and body.

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00:22:36

How I Lost 100 Pounds By Drinking Butter Coffee : 1371

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/30

This episode tells the true story of how a burned out Silicon Valley millionaire discovered a simple Tibetan drink that transformed his energy, rewrote the science of fat and metabolism, and sparked a global movement that changed how the world eats and performs.

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00:45:05

Get a Full Body Workout in 10 Minutes by Doing...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/28

This episode reveals how whole body vibration unlocks rapid circulation, lymphatic drainage, balance, and nitric oxide activation, giving you many of the benefits of a full workout while you stand still.

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01:16:15

How to Stop Brain Fog After Anesthesia | Biohacker...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/27

In this episode, Dave Asprey and Dr. Cameron Chesnut reveal how cutting edge anesthesia protocols, regenerative fat transfer, metabolic prep, peptides, ketones, hyperbarics, and non opioid pain strategies can transform any surgical procedure into a safer, faster healing, brain protected experience with dramatically improved long term results.

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00:51:10

Why Breathwork Feels Like a Euphoric Drug | Biohacker...

The Human Upgrade: Biohacking for Longevity &... ·

2025/11/25

Breathwork is one of the most powerful tools in biohacking, yet most people only experience the surface level techniques. When you use it the right way, breathwork can upgrade your brain, strengthen your nervous system, improve sleep, and open awareness states that amplify longevity and human performance.This episode features Ishan Shivanand, a globally celebrated yogic scholar, mental health researcher, and bestselling author who was raised in the monasteries of India under Mahasiddha

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