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PODCAST

This Week in Startups

Jason Calacanis

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

technology

All Episodes

01:08:49

Coreweave IPO, AVRide & Digg is Back! | E2093

This Week in Startups ·

2025/03/05

This Week in Startups is brought to you by…Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistHoratio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up.Today’s show: Jason and Alex cover CoreWeave’s filing for a $35 billion IPO after

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00:19:58

AI Agents & the Future of Work with LangChain’s...

This Week in Startups ·

2025/03/04

In this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to AI-driven automation, the importance of human-in-the-loop systems, and the future of AI-powered assistants in business. Harrison shares insights on how companies like Replit, Klarna, and GitLab are leveraging AI agents to streamline operations, plus a look ahead at what's next for AI-driven

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00:59:00

US Crypto Reserve Bombshell, Ramp’s $13B Climb, &...

This Week in Startups ·

2025/03/04

Today’s show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means for crypto markets, regulation, and startups—plus the legal and political fallout. Is this a game-changer or just another pump-and-dump controversy?*Timestamps:(0:00) Alex and Jason kick of the show!(1:48) Trump's crypto policy and PR strategy(7:14) Analysis of Trump's proposed US

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01:14:49

Board Talk Empire with GRIN's Brandon Brown, Founder...

This Week in Startups ·

2025/03/01

Today’s show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump’s token? Plus, they dive into why venture debt can destroy startups, the rise of AI-driven companies, and how Tesla is gearing up to challenge Waymo in the self-driving car race. Then, Brandon Brown from GRIN joins the show to talk about scaling to 8-figure revenue, surviving brutal market corrections, and why he’s stepping down as CEO after a decade

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01:38:42

The Incredible Double Interview: Superhuman and...

This Week in Startups ·

2025/02/27

Today’s show: Jason interviews Rahul Vohra, CEO and founder of Superhuman, and Vlad Tenev, CEO and co-founder of Robinhood. This is a packed episode featuring founder tips, fun stories about how Superhuman and Robinhood got their start and much more!Timestamps:(0:00) Episode teaser(2:13) Product market fit and founder journeys(3:25) Jason's investment in Superhuman and market positioning(5:14) AI's role and features in Superhuman(10:25) Lemon.io. Get 15% off your first 4 weeks of developer

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01:07:57

Apple Drops $500B on AI while Google Gemini Eyes Your...

This Week in Startups ·

2025/02/25

Today’s show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th birthday explores his lasting impact, Apple’s massive $500 billion AI investment, and the future of US manufacturing. The conversation dives into Outlier’s role in AI training data, its effects on journalism, and broader job market implications. Jason also shares insights on autonomous vehicles,

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00:55:56

Castelion Hypersonic Missiles and Crunchbase’s AI...

This Week in Startups ·

2025/02/22

This Week in Startups is brought to you by…Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTLinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twistAdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign.Today’s show: Jason interviews Bryon Hargis, CEO of Castelion, about the United State’s hypersonic technology gap with China, how we’re catching up and what it

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01:06:41

EV Truck Startup Nikola Runs Out of Juice | E2087

This Week in Startups ·

2025/02/20

This Week in Startups is brought to you by…Gusto. Get three months free when you run your first payroll at http://gusto.com/twistLemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistAtlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.Today’s show: Jason and Lon Harris cover Nikola’s Chapter 11 and how founders can avoid the same mistake, Superhuman AI’s new features, Mira Murati’s Thinking Machines and

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01:10:08

Is $LIBRA the End of Memecoins? with Coffeezilla | E2086

This Week in Startups ·

2025/02/19

In today's episode: Jason and Alex break down one of the craziest crypto stories yet—a $100M meme coin meltdown, insider trading, and Argentina’s president caught in the middle. Coffeezilla joins the show to explain how meme coins are rigged, why Dave Portnoy got a $5M refund while everyone else got wrecked, and what really went down with the Libra token. Plus, we debate if crypto can be fixed or if the grift is too far gone.Timestamps:(0:00) Jason and Alex kick off the show.(2:17) Libra fiasco,

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01:20:10

IPO Shakeups, NVIDIA’s Big Bets & Must-Know Founder...

This Week in Startups ·

2025/02/15

Today’s show: IPO shakeups, big AI moves, and essential founder hacks—this episode covers it all. Jason breaks down Robinhood’s 6X stock surge and his strategy for $HOOD, plus the latest on tech IPOs as Turo pulls out and SailPoint surges. We dive into AI’s open-source battle, with X.ai chasing a $10B raise and DeepSeek challenging Hugging Face. And for founders, Jason shares the startup golden rule you should break for success—plus, a brand-new startup idea he’s willing to fund right

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01:04:47

Slow Ventures' Creators Fund and Helion Energy's...

This Week in Startups ·

2025/02/12

This Week in Startups is brought to you by…Vanta. Get $1000 off your SOC 2 athttps://www.vanta.com/twistNorthwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visitnorthwestregisteredagent.com/twist today!LinkedIn Ads. Get a $100 LinkedIn ad credit athttp://www.linkedin.com/thisweekinstartupsToday’s show: Jason and Alex cover…TBDTimestamps:(0:00) Episode Teaser(1:16) Welcome Alex Wilhelm & Sam Lessin; Slow

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01:05:18

Tech's Super Bowl, Huge Earnings Week, Lon Returns...

This Week in Startups ·

2025/02/11

Today on This Week in Startups: Lon Harris is back, and we’re diving into all things Super Bowl—especially the tech takeover in this year’s commercials. We break down the biggest ad moments, from Squarespace to Uber Eats, Instacart, and even Harrison Ford’s Jeep spot. Plus, we dig into Google Trends after the ChatGPT ad, the unexpected appeal ofThe Banshees of Inisherin, and Matthew McConaughey’s latest move with Salesforce. That’s not all—France is making bold AI moves, OpenAI is getting into chip

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01:02:46

Gas Stations in Space and Carried Interest on the...

This Week in Startups ·

2025/02/08

This Week in Startups is brought to you by…Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain athttps://www.Squarespace.com/TWISTAtlassian. Head tohttps://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months.AdQuick. Visithttps://adquick.com/twist and mention TWIST to get $1000 off your first campaign.Today’s show: Jason and Alex discuss the carried interest tax loophole being in Trump’s crosshairs, a great interview with

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00:57:37

Is Palantir's Surge Just Hype | E2081

This Week in Startups ·

2025/02/06

This Week in Startups is brought to you by…Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠ Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Palantir’s surge (is it all hype?), Temo and Shein and the de minimise loop hole, Uber’s earnings and the future of self-driving

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01:06:52

Lovable's Anton Osika on Revolutionizing Software...

This Week in Startups ·

2025/02/04

OpenAI dropped Deep Research—hilariously, the exact same name as Google’s existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev’s insane growth to $10M ARR in weeks, and test whether AI can really replace software engineers. Plus, they analyze Trump’s latest tariff chaos and what it means for startups, global trade, and the economy.* Timestamps: (0:00) Jason and Alex kick off the show. (1:09) Jason’s talk and case study at Stanford (2:38) Managing the chaotic news

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01:13:16

Is OpenAI Really Worth $300B? ElevenLabs’ Series C &...

This Week in Startups ·

2025/02/01

Today’s show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI’s sky-high valuation, the surprising rise of DeepSeek’s R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the latest on AI hardware, antitrust battles, and why the “No Buy 2025” trend could change how we think about consumer tech.* Timestamps: (0:00) Jason and

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01:02:33

Boom Supersonic's Milestones, OpenAI Ethics, and...

This Week in Startups ·

2025/01/29

This Week in Startups is brought to you by…Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://northwestregisteredagent.com/twist⁠ today. Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist Today’s show: Jason and Alex cover Jason’s unique sauna experience, leading them to discuss the value of niche communities and supporting small

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00:59:49

DeepSeek Rattles Markets + SailPoint's Going Public…...

This Week in Startups ·

2025/01/27

Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity’s “buy, fix, and flip” strategy? Don’t miss this deep dive into

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00:58:24

Twilio Bets Small, DeepSeek Scares & the GameOn Fraud...

This Week in Startups ·

2025/01/24

This Week in Startups is brought to you by…Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Twilio’s team size compression, DeepSeek’s scary good AI for only $6M and the GameOn fraud

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00:59:04

Created By Humans | Sila’s Battery Evolution | E2075

This Week in Startups ·

2025/01/23

This Week in Startups is brought to you by…Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Today’s show: Alex covers The Stargate Project, other hot news items, and two great interviews. Created By Humans’ Co-founder Trip Adler talks about the future

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1,268 results

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