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PODCAST

Dr RR Baliga"s "Got Knowledge Doc" Podkast

Dr RR Baliga, MD, MBA

"Got Knowledge Doc" Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Each

science natural sciences

All Episodes

04:05

🧬Genes, Clocks, and Global Gaps: UN Insights on Aging

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/20

We unpack the UN Scientific Advisory Board Brief on Aging—from telomeres and epigenetic clocks 🧫 to senolytics 💊 and AI-driven geroscience 🤖. Why does aging matter to every clinician? Because aging is the common soil of all chronic disease. 🌱 🔗 Listen now and join the longevity conversation! #Aging #UNBrief #Geroscience #Epigenetics #Healthspan #GotKnowledgeDoc

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04:02

🧠 Brains, Beating Hearts, and Bioethics: Human Cells...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/19

🚨 Game-changing breakthroughs in chimaera research! 🧬💓 From beating human hearts grown in pig embryos to human organoids integrating into mouse intestines and brains via amniotic injection—two bold advances are reshaping the future of organ transplantation and regenerative medicine. But with scientific promise comes ethical complexity. How far should we go in creating human–animal hybrids? What safeguards are needed? 👇 Join the conversation: Are we building miracles—or crossing lines?

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03:11

Vitamin D: Broad Hopes, Narrow Proof?

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/19

🌞 New Guidelines on Vitamin D Supplementation! 💊🧪 JAMA’s latest synopsis recommends empirical vitamin D dosing—without routine testing—for children, the elderly, pregnant women, and those with prediabetes. The evidence? Conditional, with wide confidence intervals—but the low cost and minimal harm may tip the scales. Let’s discuss: Is this the dawn of “test less, dose more” in preventive medicine? #VitaminD #PublicHealth #Endocrinology #JAMA #ClinicalGuidelines #PreventiveCare

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02:39

.📜 “The Brussels Declaration 🎯: Prevent the...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/18

🚨 One in five people carry a hidden cardiovascular risk—do you? The Brussels Declaration on Lipoprotein(a) calls for global, once-in-a-lifetime Lp(a) testing to prevent premature heart disease and stroke. With strong scientific backing and health equity at its core, this is a pivotal step toward personalized cardiovascular prevention. 🧬 Let’s test early. Act early. Save lives. #LipoproteinA #BrusselsDeclaration #CVDprevention #PrecisionMedicine #HeartHealth

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03:53

Switching Gears: From Fetal Hemoglobin to Gene Therapy

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/18

From baby blood to breakthrough cures — we explore how unlocking fetal hemoglobin through gene editing (exa-cel/Casgevy) is transforming treatment for sickle cell disease and β-thalassemia. 🧬✂️ Featuring the science of BCL11A, CRISPR therapies, and what the future holds for global access 🌍💉 🎧 Tune in: “Switching Gears: From Fetal Hemoglobin to Gene Therapy” #GeneTherapy #CRISPR #HbF #BCL11A #Casgevy #SickleCell #Thalassemia #Innovation #PrecisionMedicine

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03:47

Valve by Valve: Treat Early, Treat Right, Treat Once

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/17

Treat it Early. Treat it Right. Treat it Once. New Lancet comment calls for a paradigm shift in heart valve disease care—advocating early referral, multidisciplinary heart networks, and lifetime management strategies that prioritize durability over delay. Surgery isn’t the villain—delay is. #Cardiology #HeartValveDisease #PrecisionMedicine #SurgicalInnovation #Lancet2025 #LifetimeCare #MultidisciplinaryCare

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03:38

Dr RR Baliga's Philosophical Discourses: Vasubandhu...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/17

Vasubandhu was a 4th–5th century Indian Buddhist monk, philosopher, and co-founder of the Yogācāra school of Mahayana Buddhism. Renowned for his works on Abhidharma, he developed key philosophical concepts such as “consciousness-only” (vijñaptimātra) and authored texts on Buddhist metaphysics, logic, and meditation. His influential treatises, including Abhidharmakośa and Thirty Verses, significantly shaped Buddhist thought in India, Tibet, and East Asia.

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03:19

Shear Genius: Clot Control, Microstructure Mastery,...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/16

🧠💥 New spin on stroke care! The Milli-Spinner thrombectomy device shrinks clots by up to 95% using shear + compression — no rupture, no fragments. 🚑 Achieves revascularization in 90%+ cases, even when aspiration fails. #Stroke #Innovation #NeuroTech 🔄🩸🔬 📖 https://doi.org/10.1038/s41586-025-09049-0

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06:38

🔥 Age, Immune, Inflamming: Cracking the Code of Aging...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/16

🔥 Immunosenescence + Inflammaging = Aging’s hidden engines. 🧬 New studies link immune decline to frailty, dementia, and disease. 🥗💉 Sleep, diet, vaccines, and GLP-1s may slow the clock. #Healthspan > #Lifespan 💡👴🛡️ Derived from Dr. Eric Topol’s Ground Truths on Substack.

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02:45

Beyond the Blockage: Arrhythmias, Aging, and Aortic...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/15

Heart attacks & strokes are down, but guess what’s rising? ⚡ Atrial fibrillation, 🫀 valve disease, & 🩸 VTE are taking the lead! It’s time to rethink prevention: from plaque to pulse to prognosis. 🧠💊📊 #CardioTwitter #HeartHealth #TheLancet https://doi.org/10.1016/S0140-6736(25)00990-0

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03:35

Fructose, Anxiety, Fear, and the Brain 🍭😨🧠

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/15

🧠🍬 New study in Nature reveals: High-fructose exposure in early life impairs brain development by suppressing microglial phagocytosis via GLUT5 ➡️ HK2-driven metabolic rewiring. Result? 🐭 develop anxiety-like behavior. Cut the sweet talk. Think before you drink. #NeuroScience #FructoseFacts #MentalHealth 🧪🍼

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04:28

🏃‍♂️ Weight, Wellness, and the Weakening Heart

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/14

🚨 New 2025 ACC Statement! Obesity worsens heart failure—but weight loss changes the game. 🏃‍♂️ Lifestyle helps. 💊 Semaglutide & tirzepatide show promise in HFpEF. 🔬 Rethink BMI. ⚖️ Precision + empathy = better outcomes. 👇 Dive into key takeaways. #CardioTwitter #Obesity #HeartFailure

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04:01

Forks, Frailty, and Forgetfulness 🦷➡️🧠: Mapping...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/14

👵🍽️ Malnutrition in aging isn’t just about food — it’s frailty, forgetfulness, and function. The DoMAP model 🧠🔺 reveals how low intake, high needs, and poor absorption collide with social, physical & mental challenges. Let’s fix the hidden hunger. 🥣❤️ #Geriatrics #Malnutrition #HealthyAging

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04:30

💊 Ditch the Aspirin? 🔄 P2Y12 Prevails 🛡️ After PCI

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/13

🚨 New BMJ meta-analysis! After PCI & stopping DAPT, P2Y12 inhibitor monotherapy 💊 reduces MACCE 🧠❤️ (HR 0.77) vs aspirin — without more major bleeding 💉 🫀 MI & stroke ↓ 📊 16,117 pts, 5 trials 🧠 Smarter post-PCI strategy? #CardioTwitter #BMJ #PCI #P2Y12 #Aspirin 🚫

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04:09

💉 T Cells, TCF7, and Time ⏱️: The Immune Key to...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/13

🧬 New study in Aging Cell finds immune resilience—anchored by TCF7 expression—confers a 🚀 15.5-year survival advantage! 💥 SAS-1 high / MAS-1 low = 🔑 to longevity 👵 Midlife is the window. 🧠 Age is biology, but resilience is destiny. #Longevity #Aging #Immunology #TCF7

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03:19

🫀 Hearts, Hope, and Health for All: Lancet Editorial

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/12

🫀 Cardiovascular breakthroughs abound—yet millions still die needlessly. 🌍 Innovation without equity is like a heart without a pulse. 💡 From molecules to communities, it’s time to turn science into survival. #GlobalHealth #CardioCare #EquityMatters

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03:33

Migraines: “Prodrome, Precision, Prevention 💫🧠💊”

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/12

🚨New insights from the PRODROME trial! 💊 Ubrogepant 100mg, given before the migraine hits, reduced photophobia, fatigue & brain fog—within hours! 🧠 Targets the prodrome, not just the pain. 📈 A paradigm shift in migraine care? #Migraine #CGRP #NeuroTwitter N 🔗 https://doi.org/10.1038/s41591-025-03679-7

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03:22

Finerenone + Empagliflozin: Combo Wins 🥇

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/11

💊 Big win for kidneys! In the CONFIDENCE trial, combo therapy with #Finerenone + #Empagliflozin 📉 slashed albuminuria 29–32% more than either alone in CKD + T2D patients 🧪🛡️ Safe, fast, and promising! 👥⏱️✅ #Nephrology #CardioRenal #SGLT2i #NEJM 🧬🩺

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03:35

Blindness, Breakthroughs, Biotech 🧬 From Darkness to...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/11

👁️✨ Scientists have restored infrared vision using tellurium #nanowires implanted in the retina! 🧪 Mice and primates regained light sensitivity and behavioral vision. 🚀 A bold leap toward restoring sight without bulky tech. #VisionScience #NeuroTech #Retina #Innovation

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05:12

🥃 Alcohol and 🫀 Heart Disease: Dose, Debate, and...

Dr RR Baliga"s "Got Knowledge Doc" Podkast ·

2025/06/10

🍷 Is a glass of wine a heart helper or hidden hazard? The 2025 AHA Statement says: ⚠️ Moderate = uncertain 🚫 Heavy = harmful 🫀 Risks include AFib, stroke, CAD, HF & sudden death 📊 New genetic studies challenge old myths. 👇 Know your limits. Rethink the drink. #CardioTwitter #MedEd #AHA2025

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779 results

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