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PODCAST

Xtalks Life Science Podcast

This Life Science focused podcast brings together Xtalks editorial staff to share insights into the latest B2B industry news. Xtalks connects professionals in the life science, medical device, and food industries with useful content like webinars, job opening, articles and virtual meetings.

science life sciences

All Episodes

30:15

Driving Innovations in Rare Diseases with Takeda’s...

Xtalks Life Science Podcast ·

2025/02/26

In this episode, Ayesha spoke with Anthea Cherednichenko, MPH, MBA, Vice President, Hematology Franchise Head, Takeda, who discussed driving innovation in rare diseases through collaborations focused on better serving patients and their communities.Anthea has more than a decade of global experience serving the rare disease community, particularly those with blood and bleeding disorders, at Takeda. She is a global healthcare leader with over 20 years of industry experience across the US, Europe and

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32:41

Advancing Alzheimer’s Diagnostics: Insights from...

Xtalks Life Science Podcast ·

2025/02/19

In this episode, Ayesha spoke with Lee Honigberg, PhD, VP of Research & Development, ALZpath, a provider of diagnostic tools for Alzheimer’s disease. This includes a blood-based biomarker assay, called the ALZpathDx assay, which measures pTau217 in the blood. Prior to joining ALZpath, Dr. Honigberg was most recently Senior Director and Distinguished Scientist in Translational Medicine at Genentech, where he was leading a group responsible for biomarker development for programs in

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25:26

Advancing PTSD Treatment with Digital Brain...

Xtalks Life Science Podcast ·

2025/02/12

In this episode, Vera speaks with Oded Kraft, Co-Founder, CEO and President of GrayMatters Health, a company transforming mental health care through evidence-based digital brain biomarker technology.Oded shares insights into GrayMatters Health’s mission to improve patient outcomes for mental health disorders like PTSD by leveraging their proprietary EEG-fMRI-Pattern (EFP) biomarker. He discusses how this novel technology integrates functional MRI and EEG data to address critical gaps in mental

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39:52

Innovating Immune-Modulating Therapies in Autoimmune...

Xtalks Life Science Podcast ·

2025/02/05

In this episode, Ayesha spoke with Mario Marcondes, MD, PhD, VP Head of Clinical Development at Nektar Therapeutics, a company focused on the discovery and development of novel therapies for autoimmune disorders and cancer.Dr. Marcondes is a licensed and trained physician, specializing in oncology and immune oncology. He has more than 15 years of research and teaching experience in Bone Marrow Transplant (BMT)/Cellular Therapies and more than 10 years of industry experience. He was the Program Lead

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49:25

Advancing Digital Approaches in Alzheimer’s Research...

Xtalks Life Science Podcast ·

2025/01/29

In this episode, Ayesha spoke with Sarah Averill Lott, MPH, CPH, Research Lead at Digital Medicine Society (DiMe) and Diane Stephenson, PhD, Executive Director at the Critical Path for Parkinson (CPP) at the Critical Path Institute.DiMe is a global non-profit and a professional home for digital medicine that aims to drive the broad adoption of digital approaches to advance medicine and public health. DiMe convened a working group to identify barriers to greater utilization of digital measures in

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30:57

Transformative Neuropsychiatric Therapies ft. Dr....

Xtalks Life Science Podcast ·

2025/01/22

In this episode, Ayesha spoke with Amit Etkin, Founder, President and CEO of Alto Neuroscience, a company developing precision treatments for neuropsychiatric conditions.Alto Neuroscience is focused on designing candidates that target core brain processes in patient populations not adequately treated by currently available medications. Alto is currently pursuing candidates in major depressive disorder (MDD), bipolar depression and schizophrenia. Mental health disorders are a leading cause of

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22:05

Pioneering Cancer Treatment with Alpha Radiation...

Xtalks Life Science Podcast ·

2025/01/15

In this episode, Vera spoke with Dr. Robert Den, Chief Medical Officer (CMO) of Alpha Tau Medical, a company developing cancer treatment with its highly potent alpha radiation technology.Dr. Den shared his journey to becoming CMO at Alpha Tau Medical and discussed the company’s mission to bring innovative cancer therapies to patients worldwide. Learn how Alpha Tau’s technology differs from traditional radiation therapies, the types of cancers it has shown promise in treating and the impact this

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35:23

Innovations in Immunomodulators for Diseases of the...

Xtalks Life Science Podcast ·

2025/01/08

In this episode, Ayesha spoke with Judy Chou, PhD, CEO, President and Board member of AltruBio, a company developing first-in-class immunomodulators to target diseases of the immune system.AltruBio’s pipeline includes compounds being investigated for indications such as ulcerative colitis, psoriatic arthritis and acute graft vs. host disease. Prior to joining AltruBio, Dr. Chou headed the global Biotech organization at Bayer Pharmaceuticals overseeing the development, manufacturing and distribution

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48:06

Innovating Cell-Based Solutions for Type 1 Diabetes...

Xtalks Life Science Podcast ·

2024/12/18

In this episode, Ayesha spoke with Jonathan Rigby, MBA, CEO of Sernova, a Canadian biotech company developing innovative cell therapy-based approaches for the management of type 1 diabetes. The company’s lead innovation is an implantable bio-hybrid organ pouch, which is currently in an ongoing Phase I/II clinical trial. An estimated 537 million people are currently living with diabetes globally and this number is projected to reach 643 million by 2030, making it a pressing health issue in need of

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41:51

Immune-Based Intratumoral Cancer Therapies ft....

Xtalks Life Science Podcast ·

2024/12/12

In this episode, Ayesha had a conversation with Lewis Bender, MBA, Founder, Chairman and CEO of Intensity Therapeutics, a biotech company developing first-in-class immune-based intratumorally injected cancer therapies.Intensity’s lead product candidate, INT230-6, is currently in human clinical studies for the treatment of refractory solid tumors, including metastatic soft tissue sarcoma and breast cancer. Lewis Bender has almost three decades (28 years) of biopharmaceutical leadership experience

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27:59

Targeting Cancer Drug Resistance with Kairos Pharma’s...

Xtalks Life Science Podcast ·

2024/12/04

In this episode, Ayesha spoke with John Yu, MD, CEO of Kairos Pharma, a company advancing therapies to overcome challenges in cancer drug resistance and immune suppression.Kairos is developing therapeutics that reverse cancer drug resistance in cancers such as prostate and lung cancer. The company’s lead candidate, ENV105, is an antibody targeting CD105, which is implicated in cancer cell resistance to various treatments. By inhibiting CD105, ENV105 seeks to restore the effectiveness of standard

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46:19

Innovating Immunotherapeutics with Oncolytic Virus...

Xtalks Life Science Podcast ·

2024/11/27

In this episode, Ayesha spoke with Thomas Heineman, MD, PhD, Chief Medical Officer at Oncolytics Biotech, a company developing an oncolytic virus cancer therapeutic that is currently in clinical trials for indications including metastatic breast cancer and pancreatic cancer.Oncolytics is developing a first-in-class, nonpathogenic oncolytic virus administered intravenously that activates, recruits and trains immune cells to identify and destroy cancer cells. Simultaneously, it remodels the tumor

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45:01

Laser Vision: Pioneering Laser Innovations for...

Xtalks Life Science Podcast ·

2024/11/20

In this episode, Ayesha spoke with AnnMarie Hipsley, DPT, PhD, CEO and founder of Ace Vision Group, an ophthalmic laser device company that is bringing touchless eye laser therapy to patients with age-related vision loss. Dr. Hipsley is a vision scientist, inventor, entrepreneur, author and speaker on ocular biomechanics and the biomechanical rejuvenation of the aging eye. She invented an innovative touchless laser system and a laser microporation system for the treatment of presbyopia. Presbyopia

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00:36

Bringing the Tech Revolution to Medicine with Digital...

Xtalks Life Science Podcast ·

2024/11/13

In this episode, Ayesha spoke with Shaheen Lakhan, MD, PhD, Chief Medical and Scientific Officer, Click Therapeutics, a company focused on developing software as prescription medical treatments for people with unmet medical needs.Click Therapeutics is specifically developing Digital Therapeutics, which involve the delivery of prescription treatments to patient’s smartphones. These are being developed for indications in psychiatry, neurology, oncology, immunology and cardiometabolic diseases. In

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36:40

Inside the Latest Advances in Hearing Tech ft. Envoy...

Xtalks Life Science Podcast ·

2024/11/06

In this episode, Ayesha spoke with Brent Lucas, CEO of Envoy Medical. Envoy Medical is a medical device company focused on providing cutting-edge technologies across the hearing loss spectrum. According to the National Institute of Deafness and Other Communication Disorders, 13 percent of people in the US 12 years of age and older have hearing loss in both ears, underscoring the importance of developing solutions to help this population. Brent Lucas has been the CEO of Envoy Medical Corporation for

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20:23

Advances in Heart Failure Treatment ft. Dr. Robert...

Xtalks Life Science Podcast ·

2024/10/31

In this episode, Ayesha spoke with Robert Perkins, MD, Vice President, US Medical Affairs/Renal and Cardiovascular at Bayer who spoke about recent advancements in the heart failure (HF) treatment landscape.This includes new Phase III trial data for Kerendia (finerenone) in patients with heart failure that was presented recently at this year’s European Society of Cardiology (ESC) Congress 2024. At Bayer, Dr. Perkins leads a team of medical directors and field team members working to advance the care

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29:19

Transforming Clinical Research: A Conversation with...

Xtalks Life Science Podcast ·

2024/10/23

In this episode, Vera spoke with Morgan Hanger, Executive Director of the Clinical Trials Transformation Initiative (CTTI). CTTI is a public-private partnership dedicated to improving the quality and efficiency of clinical trials, aiming to transform the industry by 2030. Hanger shares her career journey, from her roles at PatientsLikeMe and Memorial Sloan Kettering Cancer Center, to leading CTTI. She explains how her patient-centered focus has shaped CTTI’s approach to its Transforming Trials 2030

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33:24

Innovative Approaches to Antiviral Drug Development

Xtalks Life Science Podcast ·

2024/10/16

In this episode, Vera spoke with Dr. Sam Lee, Co-Chief Executive Officer and President of Cocrystal Pharma, a clinical-stage biotech company focusing on antiviral drug development with a unique structure-based drug discovery platform. With over 25 years of experience in anti-infective drug discovery, Dr. Lee brings a wealth of knowledge to the discussion on the urgent need for innovative antiviral therapies. The conversation begins with Dr. Lee sharing insights on the mission of Cocrystal Pharma,

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32:19

A Unique Approach to in vivo CAR T Therapy and New...

Xtalks Life Science Podcast ·

2024/10/09

In this episode, Vera spoke with Tim Culp, PhD, Vice President of Research and Development at Interius BioTherapeutics, a Philadelphia-based biotech company.Their lead program focuses on an intravenous CAR therapy for B cell lymphomas. Additionally, the company is advancing a second program aimed at treating autoimmune diseases. Dr. Culp joined Interius following a distinguished 14-year career with Merck Research Laboratories where he supported vaccine and oncolytic virus program development as a

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32:33

The Promise of Epigenetic Therapeutics in...

Xtalks Life Science Podcast ·

2024/10/02

In this episode, Ayesha spoke with James E. Brown, DVM, co-founder, President and CEO of DURECT.DURECT is pioneering a therapeutic strategy by leveraging the potential of epigenetic modulation to alter the trajectory of severe and life-threatening conditions like acute organ injury and cancer. The company is specifically focused on the development of an epigenetic modulator, larsucosterol (DUR-928) for the treatment of alcohol-associated hepatitis (AH). The therapeutic has shown promising results

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237 results

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