Xtalks Life Science Podcast

26:09

Pinch It to Believe It: Skin Longevity with...

Xtalks Life Science Podcast ·

2026/09/30

In this week’s episode of the Xtalks Life Science Podcast, host Soumya Shashikumar speaks with Anne-Cécile Chevrier, Global Head, Injectable Aesthetics at Galderma, about the science of skin quality and why the field is increasingly looking at “skin longevity” — keeping skin healthier, more functional and resilient for longer.Anne-Cécile explains that skin quality is about how skin looks, feels and functions, including hydration, firmness, radiance and texture. She also discusses how menopause and

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12:32

Tackling Fluid Overload: Nuwellis CEO Mike McCormick...

Xtalks Life Science Podcast ·

2026/09/16

In this week’s episode of the Xtalks Life Science Podcast, host Dr. Mohammad Ali speaks with Mike McCormick, President and CEO of Nuwellis, about fluid overload, the heart-kidney connection and what happens when diuretics stop working as expected.Mike explains that fluid overload is “not simply a cosmetic swelling.” Persistent congestion can make breathing difficult, reduce appetite and even make it hard for patients to lie flat. He also describes the cardiorenal balancing act, where worsening

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27:42

Rethinking Acute Pain Management: The Next Frontier...

Xtalks Life Science Podcast ·

2026/09/02

In this week’s episode of the Xtalks Life Science Podcast, host Dr. Mohammad Ali speaks with James Hackworth, PhD, Cebranopadol Development Lead at Tris Pharma, about the clinical challenges of providing effective acute pain relief while limiting the treatment-related risks of traditional opioids.James explains that when severe pain is poorly treated, prolonged pain signaling can, in some cases, lead to lasting changes in the nervous system through neuroplasticity. He also describes how targeting

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23:36

Why Endometriosis Can Be So Difficult to Diagnose...

Xtalks Life Science Podcast ·

2026/08/19

In this week’s episode of the Xtalks Life Science Podcast, host Dr. Mohammad Ali, Life Science Writer and Knowledge Translation Specialist at Xtalks, spoke with Dr. Farideh Bischoff, Chief Medical Officer at HerAnova Lifesciences, about the challenges of diagnosing endometriosis and research into non-invasive testing.Dr. Bischoff explains that symptom severity does not always reflect disease extent, and symptoms can overlap with conditions such as irritable bowel syndrome and adenomyosis

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23:31

Why Gout Is Often Misunderstood: Treatment and...

Xtalks Life Science Podcast ·

2026/08/05

In this week’s episode of the Xtalks Life Science Podcast, host Soumya Shashikumar, Senior Life Sciences Journalist at Xtalks, spoke with James Mackay, CEO of Crystalys Therapeutics, about gout, persistent misconceptions surrounding the condition and current clinical research.Gout is often linked primarily to diet and alcohol. James explains that many patients instead have difficulty removing enough uric acid from the body, allowing crystals to accumulate in the joints and contribute to

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33:39

Addressing Neonatal Brain Injury: HIE Treatment...

Xtalks Life Science Podcast ·

2026/07/24

In this week’s episode of the Xtalks Life Science Podcast, host Soumya Shashikumar, Senior Life Sciences Journalist at Xtalks, spoke with Dr. Kia Motesharei, President and Chief Operating Officer of ReAlta Life Sciences, about hypoxic-ischemic encephalopathy (HIE) and efforts to develop treatments beyond therapeutic hypothermia.HIE is a serious neonatal brain injury caused by insufficient oxygen and blood flow to the brain around the time of birth. Therapeutic hypothermia, or controlled cooling,

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28:07

Why Endometriosis Needs New Treatment Approaches with...

Xtalks Life Science Podcast ·

2026/07/08

In this week’s episode of the Xtalks Life Science Podcast, host Vera Kovacevic, Editor-in-Chief at Xtalks, spoke with Dr. Tanya Petrossian, CEO and Founder of EndoCyclic Therapeutics, a biopharmaceutical company developing a non-hormonal therapeutic approach for endometriosis. Endometriosis affects many women, but it is still often difficult to diagnose, treat and fully understand. For many patients, available treatment options have historically centered on hormone-based therapies or surgery,

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25:43

Precision Oncology in Lung Cancer with Boehringer...

Xtalks Life Science Podcast ·

2026/06/24

In this week’s episode of the Xtalks Life Science Podcast, host Vera Kovacevic, Editor-in-Chief at Xtalks, spoke with two experts from Boehringer Ingelheim: Itziar Canamasas, PhD, Global Head of Oncology and Senior Vice President, and Volker Teichgräber, MD, Senior Vice President and Head of Global Experimental Medicine Oncology. The conversation focused on how precision oncology is changing the way advanced non-small cell lung cancer (NSCLC) is diagnosed, studied and treated. As molecular testing

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24:13

Sustainability in Asthma and COPD Drug Development...

Xtalks Life Science Podcast ·

2026/06/10

In this week’s episode of the Xtalks Life Science Podcast, host Vera Kovacevic, Editor-in-Chief at Xtalks, spoke with Diego Ardigò, Executive Vice President, Global R&D at Chiesi, a biopharma company focused on respiratory health, rare diseases and specialty care.Respiratory medicine presents unique drug development challenges because successful therapies depend not only on the drug itself, but also on the formulation and delivery device. As innovation continues across asthma and chronic

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26:00

What’s Next in Cardiometabolic Disease Drug...

Xtalks Life Science Podcast ·

2026/06/04

In this week’s episode of the Xtalks Life Science Podcast, host Vera Kovacevic, Editor-in-Chief at Xtalks, spoke with Hyung Heon Kim, CEO of MetaVia, a clinical-stage biotechnology company developing treatments for cardiometabolic diseases.Mr. Kim discusses the evolving cardiometabolic disease landscape, including the connections between obesity, diabetes, liver disease and cardiovascular risk. He shares his perspective on how obesity care has changed in recent years, where unmet needs remain and

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37:43

How Real-World Evidence Is Shaping Inclusive Clinical...

Xtalks Life Science Podcast ·

2026/05/27

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Awny Farajallah, MD, Chief Medical Officer at Takeda, about the growing role of real-world evidence in improving clinical trial inclusivity and diversity. Also hear Dr. Farajallah discuss innovations in diseases such as narcolepsy type 1 and polycythemia vera, and how new technologies are transforming healthcare data into actionable insights. With over two decades of

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38:09

Stem Cell Therapies for Degenerative Disc Disease and...

Xtalks Life Science Podcast ·

2026/05/20

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Lance Alstodt, CEO, BioRestorative & Francisco Silva, Chief Scientist & VP, R&D, BioRestorative Inc. (NASDAQ:BRTX), a regenerative medicine company developing stem cell-based therapies and products. The company’s clinical programs target critical healthcare needs, including degenerative disc disease and metabolic disorders.Lance Alstadt has over 25 years of

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30:48

New Blood Test for Early Alzheimer’s Detection with...

Xtalks Life Science Podcast ·

2026/05/13

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Alessio Travaglia, PhD, Neuroscientist and Director of Translational Science at the Foundation for the National Institutes of Health (FNIH).New findings from a study published in Nature Medicine suggest that a single blood test may be able to predict the onset of Alzheimer’s symptoms within a three- to four-year period. Dr. Travaglia discusses how the test works, what

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29:54

Targeting Ischemic Disease with DiaMedica CEO Rick Pauls

Xtalks Life Science Podcast ·

2026/05/06

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke Rick Pauls, President and CEO of DiaMedica Therapeutics (Nasdaq: DMAC), a company advancing multiple programs in challenging vascular conditions driven by ischemia, including preeclampsia (PE), fetal growth restriction (FGR) and acute ischemic stroke (AIS).DiaMedica’s therapeutic approach in ischemia-based diseases centers on a recombinant form of the KLK1 protein, which

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54:45

Why Copyright Matters in Life Sciences in the Age of...

Xtalks Life Science Podcast ·

2026/04/29

In this special episode of the Xtalks Life Science Podcast, part of our Breakthrough with Dr. Corey Stanton series, host Dr. Corey Stanton speaks with Neal Dunkinson, Sr. Director of Solution Sales at Copyright Clearance Center (CCC), about why copyright and licensing are becoming mission-critical in modern life sciences research, particularly in the era of AI. Life sciences teams both generate and consume vast amounts of scientific literature, clinical data and third-party content. As Neal

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42:16

Neuromodulation and Nerve Ablation for Chronic Pain...

Xtalks Life Science Podcast ·

2026/04/22

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Dave Rosa, CEO, NeuroOne Medical Technologies Corporation, a company developing minimally invasive diagnostic and therapeutic electrodes employed in nerve ablation as well as neuromodulation devices to treat conditions such as epilepsy and chronic pain and enable drug delivery into the brain.Mr. Rosa is an entrepreneur with three decades of experience in the medical

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37:02

Off the Shelf Cell Therapies for Bone Marrow...

Xtalks Life Science Podcast ·

2026/04/15

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Kevin Caldwell, CEO, Co-Founder & President of Ossium Health, a biotechnology company advancing the first off-the-shelf bone marrow therapy derived from deceased organ donors. The treatment is designed to address longstanding clinical and logistical challenges in allogeneic bone marrow transplantation.Kevin Caldwell has led Ossium Health in building more than 50

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28:30

Scalable Biologics Production Trends: Featuring Omar...

Xtalks Life Science Podcast ·

2026/04/08

In this episode of the Xtalks Life Science Podcast, part of the Breakthrough with Dr. Corey Stanton series, host Dr. Corey Stanton sits down with Dr. Omar Wahab, Vice President of Bioprocessing at Lonza, to explore the increasingly strategic role of cell culture media in enabling scalable biologics manufacturing.As biologics pipelines continue to expand across therapeutic areas such as oncology, immunology and advanced therapies, upstream development decisions are taking on new importance in

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40:04

Novel Therapeutic and Trial Approaches for Lysosomal...

Xtalks Life Science Podcast ·

2026/04/01

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Alex Yang, JD, LLM, CEO of Polaryx, a company focused on developing disease-modifying small molecule therapies for rare, pediatric lysosomal storage disorders.Alex is a biotech executive and investor with over 25 years of experience spanning law, private equity, cross-border fund formation and strategic leadership across the biopharmaceutical sector. He currently

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21:33

Psilocybin Treatments for Treatment-Resistant...

Xtalks Life Science Podcast ·

2026/03/25

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks, spoke with Steve Levine, MD, Chief Patient Officer at Compass Pathways, a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health.One of the areas that Compass Pathways is working in is the development of psilocybin-based treatments for treatment-resistant depression (TRD). Dr. Levine is a board-certified psychiatrist who has

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