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PODCAST

What"s Your Problem?

iHeartPodcasts and Pushkin Industries

Every week on What"s Your Problem?, former Planet Money host Jacob Goldstein talks withentrepreneurs and engineerstackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What"s Your Problem? learns from the thinkers and doers trying to make our future

technology entrepreneurship

All Episodes

37:18

Teaching Robots How to Do Everything

What"s Your Problem? ·

2025/06/05

AI is better than humans at a lot of things, but physical tasks – even seemingly simple ones like folding a shirt – routinely stump AI-powered robots. Chelsea Finn is a professor at Stanford and the co-founder of Physical Intelligence. Chelsea's problem is this: Can you build an AI model that can teach any robot to do any task, anywhere? Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can

en-US

38:19

Making a Universal Flu Vaccine

What"s Your Problem? ·

2025/05/29

Jacob Glanville is the founder and CEO of Centivax. Jacob’s problem is this: Can you create a vaccine that protects people against almost all strains of flu – even strains that haven’t evolved yet? Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin shows. Subscribe on Apple:

en-US

36:16

Teaching Computers to Smell

What"s Your Problem? ·

2025/05/22

Alex Wiltschko got obsessed with perfume when he was 12 years old. He grew up to be an AI researcher at Google. Then he started Osmo, a company that fused his job at Google with his childhood obsession: Osmo is using AI to teach computers to smell.The company is getting into the perfume business, and it plans eventually to use scent to diagnose disease and detect security risks. Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm

en-US

25:39

China’s Race to Dominate: Listen to Global Tech Wars

What"s Your Problem? ·

2025/05/01

For decades, China’s economic rise has been symbolized by its unstoppable force of low-cost manufacturing. Now, it’s the leading country in cutting-edge industries like artificial intelligence, electric vehicles, surveillance technology, and more. In Global Tech Wars, Financial Times’ veteran journalist James Kynge analyzes China’s rapid technological ascent and what it means for the future. Enjoy this preview of Global Tech Wars: China’s Race to Dominate. If you like

en-US

45:42

Can a Chatbot Treat Depression?

What"s Your Problem? ·

2025/04/24

Nick Jacobson and his team at Dartmouth medical school spent over 100,000 hours trying to build an AI chatbot that can serve as a safe, effective therapist. After a few false starts, they seem to be on to something.Note: This episode contains references to self harm. Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all

en-US

47:03

Will AI Radically Change the World by 2027?... from...

What"s Your Problem? ·

2025/04/23

This week, Nate and Maria discuss AI 2027, a new report from the AI Futures Project that lays out some pretty doom-y scenarios for our near-term AI future. They talk about how likely humans are to be misled by rogue AI, and whether current conflicts between the US and China will affect the way this all unfolds. Plus, Nate talks about the feedback he gave the AI 2027 writers after reading an early draft of their forecast, and reveals what he sees as the report’s central flaw. Enjoy this episode

en-US

41:17

Is the Future of Flight Supersonic?

What"s Your Problem? ·

2025/04/17

Blake Scholl is the founder and CEO of Boom Supersonic. Blake's problem is this: Can you build a commercial airplane that flies faster than the speed of sound – and that makes economic sense? Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin shows. Subscribe on Apple: apple.co/pushkinSubscribe on Pushkin:

en-US

25:20

The Secrets of Silk

What"s Your Problem? ·

2025/04/10

Fiorenzo Omenetto is a professor of biomedical engineering at Tufts University and the director of Silklab. Fiorenzo's problem is this: How do you turn a material people have been using for thousands of years into useful, cutting edge tools that improve everything from vaccine delivery to food waste? Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive

en-US

33:14

Infiltrating an International Ransomware Gang

What"s Your Problem? ·

2025/04/08

A few years ago, a ransomware gang called LockBit rose from obscurity to extort over $100 million from organizations around the world. A security strategist named Jon DiMaggio wanted to understand how the organization worked. So he used the techniques of World War II-era spycraft to make contact with the hackers.On today’s show, Jon tells the story of LockBit – from the way it borrowed techniques from mainstream companies to market itself and attract talent, to the response from

en-US

55:09

Preparing for the Future of War

What"s Your Problem? ·

2025/04/03

Christopher Kirchhoff helped launch a Defense Department office that aimed to bring Silicon Valley technology to the US military. Christopher’s problem is this: How can the giant bureaucracy that is the US military keep up with technological change? Get early, ad-free access to episodes of What's Your Problem? by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin

en-US

27:56

Stopping HIV Without a Vaccine

What"s Your Problem? ·

2025/03/13

Jared Baeten is senior vice president in virology at Gilead Sciences. Jared's problem is this: In a world without a vaccine, how do you make a medicine that people will actually take to help prevent HIV?There’s already a daily pill that reduces the risk of getting HIV, but a majority of people who are at high risk are unwilling or unable to take it.So Jared and his colleagues are developing a new drug, lenacapivir, designed to be given as a shot once every six months. Note: The views and

en-US

49:26

Harnessing the Heat Deep Beneath Our Feet

What"s Your Problem? ·

2025/03/06

Carlos Araque is the co-founder and CEO of Quaise Energy. Carlos' problem is this: How do you make drilling for geothermal energy as routine, widespread, and profitable as drilling for oil or gas? The answer involves digging deeper into the Earth than anyone has ever dug before.See omnystudio.com/listener for privacy information.

en-US

29:11

The Brain Implant That Could Change Medicine

What"s Your Problem? ·

2025/02/27

Ben Rapoport is the co-founder and CSO of Precision Neuroscience. Ben's problem is this: Can you build a device that allows a paralyzed person to use a computer with only their thoughts – without damaging their brain?See omnystudio.com/listener for privacy information.

en-US

45:24

Building a Mass Market Robot

What"s Your Problem? ·

2025/02/20

Jeff Cardenas is the co-founder and CEO of Apptronik. Jeff's problem is this: Can you make a safe, reliable humanoid robot – for less than $50,000? In the short term, Apptronik’s robots will work in factories. But Jeff’s long-term goal – based on the experience of his own grandparents – is to build robots that can help care for the elderly.See omnystudio.com/listener for privacy information.

en-US

43:35

Solving Solar’s Biggest Problem

What"s Your Problem? ·

2025/02/13

We need better, cheaper ways to store solar and wind energy when it’s dark out and the wind isn’t blowing. One option: Compressing air in underground caverns when energy is abundant, then blowing it back out to create energy when you need it. It’s an old idea, but it has some fundamental problems. Curtis van Wallingham, the co-founder and CEO of Hydrostor, thinks his company has solved those problems with a new approach. If he’s right, his firm will help fix the biggest

en-US

54:43

How Bubbles Power Breakthroughs

What"s Your Problem? ·

2025/02/06

There are moments in history when people make huge technological advances all of a sudden. Think of the Manhattan Project, the Apollo missions, or, more recently, generative AI. But what do these moments have in common? Is there some set of conditions that lead to massive technological leaps? Byrne Hobart is the author of a finance newsletter called The Diff, and the co-author of Boom: Bubbles and the End of Stagnation. In the book, Bryne makes the case for one thing that is really helpful if you

en-US

51:24

Teaching AI to Build Stuff in the Physical World

What"s Your Problem? ·

2025/01/30

AI works well in the virtual world. That’s partly because the internet provides so much data to train AI models. But there’s no analogous data set for the physical world – and as a result, AI doesn’t work as well there… yet. Edward Mehr is the co-founder and CEO of Machina Labs. Edward's problem is this: How can you use AI to turn robots from dumb, inflexible machines into skilled, versatile craftsmen?See omnystudio.com/listener for privacy information.

en-US

44:24

NVIDIA: At the Heart of the AI Boom

What"s Your Problem? ·

2025/01/23

In the past few years, NVIDIA has become one of the most valuable and important companies in the world by making GPUs, the chips powering the AI boom. But where did the company come from, and why are NVIDIA chips the ones that dominate AI? Tae Kim is the author of a new book called The Nvidia Way. In his book, he tells the story of how NVIDIA’s founder and CEO, Jensen Huang, set NVIDIA on the path to becoming what it is today.See omnystudio.com/listener for privacy information.

en-US

42:05

What Claude Shannon Figured Out

What"s Your Problem? ·

2025/01/16

Claude Shannon is a major figure in the history of technology. Known as the father of information theory, Shannon spent decades at Bell Labs and MIT. But what exactly did Claude Shannon figure out, and why is it so important?To answer that question, Jacob talked with David Tse, a professor of electrical engineering at Stanford who studied under one of Shannon’s students, and who teaches Shannon to his own students today. David used Shannon's work to make a breakthrough in wireless

en-US

30:30

Measles: The Cancer Killer?... from Incubation

What"s Your Problem? ·

2024/12/19

We thought we knew everything there was to know about measles. But in recent years, new research has revealed that the virus attacks the immune system and creates effects far more dramatic than a rash and fever. For this episode we’re joined by Michael Mina, a former Harvard epidemiologist now at eMed, who helped discover how measles was causing “immune amnesia.” Our second guest is Stephen Russell, a former Mayo Clinic researcher who co-founded a company called Vyriad. Russell is

en-US

197 results

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