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PODCAST

Mendelspod Podcast

Offering a front row seat to the Century of Biology, veteran podcast host Theral Timpson interviews the who"s who in genomics and genomic medicine. www.mendelspod.com

science & medicine natural sciences

All Episodes

23:47

Erica Ramos on Her Pioneering Role as Genetic...

Mendelspod Podcast ·

2016/09/14

For the next installment of our series on genetic counseling, we’re joined by Erica Ramos. She’s the president-elect of the National Society of Genetic Counselors and was the second genetic counselor hired at Illumina where she’s been for four years. Illumina now has 15 genetic counselors.Erica has been a trail blazer throughout her career. Before joining Illumina, she was the first ‘cancer counselor’ in the city of Las Vegas, Nevada. Her time at Illumina has been a prime example of the evolving

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17:36

August 2016 with Nathan and Laura

Mendelspod Podcast ·

2016/09/01

It’s the end of summer and end of another month. Joining us to discuss the genomics headlines of August are Laura Hercher and Nathan Pearson.A recent study demonstrating that breast cancer patients with low genomic risk may not need chemotherapy is just what precision medicine is all about, isn’t it? Theral and Laura think the study is a big deal. Nathan’s not so sure.Nathan is convinced though that Eurocentric studies have implicit racism. Laura agrees, saying the lack of racial diversity in

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24:34

A Maniacal Commitment to Science: Peering into...

Mendelspod Podcast ·

2016/08/18

Today we feature a pharma company that has been around for some time but recently getting more media coverage for the impressive scale of their new genetic center. Regeneron Pharmaceuticals, insiders joke, has been an overnight success that took 25 years.One might think every big pharma company has their own genetic center for internal R & D. But today’s guest, Jeff Reid, Executive Director of Genome Informatics at the Regeneron Genetic Center (RGC), says that actually deep genetic research is

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17:08

The Days of Miracle and Wonder: Laura Hercher on...

Mendelspod Podcast ·

2016/07/30

We often hear at conferences that there are too few genetic counselors. And that this bottleneck is constraining the delivery and promise of genomic medicine. Is this true?It is 100% true, says Laura Hercher of Sarah Lawrence College in the second part of our interview on genetic counseling.“We graduate just under 300 genetic counselors a year. And last year at our annual meeting [National Society of Genetic Counselors], there were posted over 600 jobs. We’re producing jobs at a much greater

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21:35

The Days of Miracle and Wonder: Laura Hercher on...

Mendelspod Podcast ·

2016/07/30

They’ve been called the “unsung heroes” of our age. They are primarily women. And when the trend for most of us is to become specialists, they have been generalists.Today we begin a special series on genetic counselors. Our first guest, a genetic counselor herself, is a name familiar to our audience. Laura Hercher is one of our regular month-in-reviewers, and today it’s all about her. She is on the faculty at Sarah Lawrence College where the first genetic counseling program was begun in 1969

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20:59

A Precision Medicine Platform Comes of Age: Jonathan...

Mendelspod Podcast ·

2016/07/21

Today’s show with Jonathan Hirsch, the President and co-founder of Syapse begins a couple years ago. We first featured him on the program in January of 2014 with the headline, Is this the Omics-to-Clinic Site We’ve All Been Waiting For? This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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15:40

FDA’s Liz Mansfield on New NGS Guidances

Mendelspod Podcast ·

2016/07/19

On July 6th, as part of the President’s Precision Medicine Initiative, the FDA issued two new draft guidances for the oversight of next gen sequencing (NGS) tests. The first guidance is for using NGS testing to diagnose germline diseases. In the second, the FDA lists guidelines for building and using genetic variant databases.To help us understand just what the guidance is and what led to its release, we’re joined by Liz Mansfield, the Deputy Office Director for Personalized Medicine at the FDA

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20:08

How Is the Brexit Impacting Genomics? with Clare...

Mendelspod Podcast ·

2016/07/12

Today's guests have been separately on the program recently. And we've asked them, both Brits, to come back on for a discussion of the Brexit. Clare Turnbull is Clinical Lead for the 100K Genomes Project Cancer Program at Genomics England. Hadyn Parry is the CEO at Oxitec, a company based in Oxford which is already selling their genetically engineered mosquitos into Brazil to deal with viral diseases like Zika and Dengue Fever. This is a public episode. If you'd like to discuss this with other

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19:52

It’s Not Really Bulls and Bears: John Carroll on His...

Mendelspod Podcast ·

2016/07/07

John Carroll has been the editor-in-chief at Fierce Biotech for thirteen years. Now he's moved to a new gig. Two weeks ago, he and a former colleague launched a new and independent life science media site, Endpoints. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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23:42

June 2016 with Nathan and Laura: GMO Labeling,...

Mendelspod Podcast ·

2016/07/05

Today's show was recorded July 1st, the first day that Vermont’s GMO labeling law went into effect. Just how big a win was this for the anti-GMO crowd, we ask our two commentators, Nathan Pearson and Laura Hercher. They have a surprisingly optimistic take, suggesting that the GMO labeling could become a positive marketing tool. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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35:31

Know Then Thyself: Kari Stefansson, deCODE genetics

Mendelspod Podcast ·

2016/06/30

Kari Stefansson is a name well known in the field of human genetics. His founding of deCODE genetics in his native Iceland in 1996 took our field into a new frontier with the unique opportunity to work with not only a homogenous population but also to integrate with a large centralized healthcare database. It also surfaced a huge ethical debate about genomic privacy. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit

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19:12

Sequenom Patent Loss a Threat to Personalized...

Mendelspod Podcast ·

2016/06/29

It’s a non-decision with big implications. On Monday, the Supreme Court turned down an appeal by Sequenom in their patent case with Ariosa. The rebuff by the highest court kills Sequenom’s prenatal screening test patent for good. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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18:51

Bringing Home Some Diagnostics Gold: Brad Gray,...

Mendelspod Podcast ·

2016/06/24

You hear it everywhere. And it’s getting old. That "diagnostics is a tough slog.” That it’s the “redheaded stepchild of healthcare.”And today’s guest doesn’t disappoint, repeating both these phrases. But Brad Gray and NanoString can claim some big “slogging" success. They’re coming out on top in diagnostics through some clever business strategy built on a solid platform. Made CEO at just 33 years of age, Brad has taken NanoString public and overseen a successful expansion from the research

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21:56

Mukherjee Mess-up, the Secret Harvard Meeting, and...

Mendelspod Podcast ·

2016/06/06

Today we look back on the genomics headlines over the past month (and a few days). To do this we’re joined by our regular commentators, Nathan Pearson and Laura Hercher.First we take on the science journalism kerfuffle of the year. When Pulitzer Prize winning author, Siddhartha Mukerjee, got epigenetics wrong in his New Yorker piece, scientists came out en masse to denounce it. Nathan reassures us that scientists aren’t afraid of writers. This is a public episode. If you'd like to discuss this

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23:35

When Do We Move to Population Based Cancer Screening...

Mendelspod Podcast ·

2016/05/24

Last year when we were promised a soon-to-be-on-the-market, pan cancer, genetic based screening test, many of us were taken aback at the hubris. Not only does the science have a ways to go, there are deep ethical conflicts to work through. However, cancer screening based on a patient’s genetics is already being done in certain niche areas. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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25:29

The Solid Future of Liquid Biopsies with Michael...

Mendelspod Podcast ·

2016/05/19

There’s been lots in the news this past year about liquid biopsies—those non-invasive tests which locate biomarkers in a vial of blood. Much of that press (perhaps too much) has been about using these blood tests for cancer screening: predictive tests that could be available to consumers some time in the future. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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25:05

Genomics Is Oversubscribed, Says Creator of BLAST

Mendelspod Podcast ·

2016/05/12

One of the original Celera team that worked on the Human Genome Project, Gene Myers is now setting up the new Center for Systems Biology at the Max Planck Institute of Molecular Cell Biology and Genetics.However, unlike many others such centers, the main focus of this institute will not be genomics. Rather Myers is going for microscopy.“Genomics is only about 20% of it,” he says in today’s interview from his office in Dresden, Germany This is a public episode. If you'd like to discuss this with

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28:32

With 10K Genomes Sequenced, Genomics England in High...

Mendelspod Podcast ·

2016/05/05

We’ve heard on the program over the past few years that genomic medicine will probably take off first in a country with a centralized health service. And when the U.K. announced their 100K Genomes Project at the end of 2012 with the creation of Genomics England in 2013, it was certainly a bold visionary move to do just that—to put the entire country on a progressive path toward precision medicine for all.So with 10K genomes sequenced, how is the project going? This is a public episode. If you'd

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22:08

April 2016 with Nathan and Laura: Big Money, More...

Mendelspod Podcast ·

2016/05/02

This month we saw Big Money being infused into genomics and other life science research projects. There’s no question that science is big business, but do we see improved healthcare as a result?Was the NIH too hasty in it’s ban on gene editing of human embryos?Superheroes are lurking among us everywhere . . . or so the mainstream media would have us believe in their take on a new study from the Icahn School of Medicine. This is a public episode. If you'd like to discuss this with other subscribers

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33:05

A Sneak Peek into the Future of Clinical Genomics...

Mendelspod Podcast ·

2016/04/28

We hear from some that soon each baby's genome will be sequenced at birth. This vast amount of genomic information will be stored in a person's medical record for life and be referenced for personalized healthcare, be it for a diagnostic, a prognostic, or a prediction. But others say that it is still way too early to be generating so much information on each person when we know so little about the genome. This camp argues that we should deal with patients on a case by case basis using a more

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563 results

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