Mendelspod Podcast

19:07

Cancer Researcher Tim Triche on the Staying Power of...

Mendelspod Podcast ·

2015/07/14

In the second part of our interview with Tim Triche, Director of the Personalized Medicine Center at Children’s Hospital Los Angeles, Tim says that micro arrays are still a vital technology for today’s cancer researcher. Making use of both next-gen sequencing and arrays for his research, Tim confirms that arrays still have advantages in the clinic as well, such as quicker turn around time. Tim also weighs in on some ongoing questions about whether poor biospecimen quality is hampering research

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24:45

Want Answers? Look to the Non-Coding Region of the...

Mendelspod Podcast ·

2015/07/09

Listen to Tim Triche from Children's Hospital Los Angeles for very long and you’ll get excited again about cancer research. I couldn’t stop listening. Which is why his interview is being published in two parts.Now sure, like other guests we’ve had on the show, Tim calls this the “absolute golden age of biomedical research.” But Tim has a unique story. He has been, and is still - though less so now, he says - an outlier in cancer genomics. Whereas most cancer researchers talk about genes, Tim is more

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32:56

Ivan Oransky on Today's Retraction Boom

Mendelspod Podcast ·

2015/07/07

When science journalist Ivan Oransky co-founded Retraction Watch, a blog with the express purpose of making scientific retractions more public, he didn’t think he would be posting much.“Adam Marcus, my co-founder, was quoted as saying, ‘yeah, we figured we’d post periodically, our mothers would read it, they’d be very happy, nobody would read it other than them.’ Obviously that hasn’t been the case,” says Oransky in this first of a series of podcasts on scientific integrity. This is a public

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5:36

Genomics-Palooza, Diagnostics Fraud, and Biblical...

Mendelspod Podcast ·

2015/06/26

What a week for Americans . . . What a week for genomics!The Supreme Court rulings that Americans can keep their Obamacare and can all get married - no matter what state they live in - added the final good news to a week of genomics festivities around the country.But it's not all positive news this week. The New York Times featured a diagnostics company under review by Medicare for fraud. Allegedly, the New Orleans based Renaissance Rx has been paying doctors to sign up patients for a huge trial of

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29:12

Ethical Issues around Editing Human Germline for the...

Mendelspod Podcast ·

2015/06/24

Art Caplan is a prodigious writer on the topic of medical ethics. How prodigious? How about thirty-two books and over 700 peer reviewed papers on ethical conundrums ranging from organ donation to end of life care. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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6:23

We Got Research, PCSK9 Inhibitors, and Clinical...

Mendelspod Podcast ·

2015/06/19

The international BIO convention is all about seduction. All fifty states sent representatives to Philly this week to make the case that their state was the best for biotech. Seventy countries were there touting their awesome awesomeness. Does all this seduction really work?A new class of drugs for cardiovascular disease was reviewed recently at the FDA. Will they become blockbusters like Pfizer’s Lipitor? This is a public episode. If you'd like to discuss this with other subscribers or get

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27:03

The Multi-Platform Approach to Clinical Sequencing...

Mendelspod Podcast ·

2015/06/15

Before Bobby Sebra became the Director of Technology Development at the Icahn School of Medicine at Mt Sinai in New York he worked at Pacific Biosciences, helping to develop their single molecule, long read (SMRT) sequencing technology. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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5:32

So That Happened, The Mad Genius, and Selling SynBio

Mendelspod Podcast ·

2015/06/12

It’s a week of finding out again what we already knew. First that a nobel laureate can also be a total ***hole. And second that creative people really are crazy.It’s also been a week for going into the future. This week Team Mendelspod attended IndieBio’s Demo Day. Twelve, mostly very young, founder/geeks pitched their new ideas for making the world a better place to a room of investors in downtown San Francisco. We saw some amazing technology, but the real question seems to be, how will they

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5:10

Summer Genomics Festival, the Other Sports Genes, and...

Mendelspod Podcast ·

2015/06/05

Gene and Tonic for June 5, 2015What does genomics have to do with a hippie rock music event? A few things. Find out in today’s humorous preview of the Festival of Genomics, happening later this month in Boston. Yes, there are the sports genes everyone knows about. But what about those less studied that might affect your career in sports? Do you know what is written on the sports page of your genome?And what has Ben Carson considering brain surgery? Tune in to this week’s wrap of genomics news

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22:32

The Sports Genes with Jeremy Koenig, Athletigen

Mendelspod Podcast ·

2015/06/04

Jeremy Koenig is a molecular biologist and an athlete. His interest in both led him to found a new direct-to-consumer genetic testing company called Athletigen. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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18:12

Woodstock for Genomics? Richard Lumb and Carl Smith...

Mendelspod Podcast ·

2015/06/02

If you haven’t already, check out the inaugural Festival of Genomics being held in Boston later this month. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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5:23

Geneticists Anonymous, the Sad State of Science...

Mendelspod Podcast ·

2015/05/29

Gene and Tonic: May 29, 2015Did you hear? The Age of Genomics has come to an end. According to science journalist, David Dobbs, after 110 years of studying genomics, we have come up with almost nothing to improve human health, or as Dobbs put it so elegantly, we ain't got "diddly-squat." What will all of our geneticist friends do? They don't want to be known as "diddlly-squaticists." This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes,

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31:02

The 9 Billion People Problem: Rod Wing on Plant Genomics

Mendelspod Podcast ·

2015/05/27

By 2050, there will be 9 billion people on the planet. What will they eat?This is the question that led Rod Wing, Director of the Arizona Genomics Institute, into the field of plant genomics. What has been accomplished so far in the mission to come up with some super green crops? And how does Rod see anti-GMO sentiment and the recent trend toward gluten free diets factoring in? This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit

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26:02

Should We Hold Back the Reins on Biotechnology? with...

Mendelspod Podcast ·

2015/05/22

A very unique biotechnology event took place this week.BEINGS 2015, or the Biotech and the Ethical Imagination Global Summit, was held at The Tabernacle, a former church turned concert hall in Atlanta, Georgia. The venue was not the only unusual thing for a summit about science. Speakers at the meeting included a well known linguist, a famous Canadian novelist, and Catholic rector along with professors of bioethics, law, and, of course, biology. This is a public episode. If you'd like to discuss

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21:44

Are We Ready to Trust Liquid Biopsies? with Milena...

Mendelspod Podcast ·

2015/05/19

If you followed the news from the recent show of the American Association for Cancer Research (AACR), no doubt you heard about the exciting potential of liquid biopsies. These new blood-based tests, made possible by better tools and analysis techniques, offer a non-invasive way of understanding various cancers. Traditionally, with non-hematological cancers, solid tumor biopsies are obtained through surgical recession or an invasive needle. This is a public episode. If you'd like to discuss this

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5:52

Gene and Tonic: Boxing for Cancer, Dubious...

Mendelspod Podcast ·

2015/05/15

In a keynote talk this week for the online Genetics and Genomics conference, computational biology whiz, John Quackenbush, listed some pretty wild correlations found by a Harvard Business School student when he mixed some large data sets. For example, U.S. spending on science, space, and technology corresponds directly with suicides by hanging, strangulation and suffocation. We never would have guessed it without the help of big data. This is a public episode. If you'd like to discuss this with

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17:00

New Patient Focused Genome Magazine Signing up Many...

Mendelspod Podcast ·

2015/05/12

Just as biomedical research is experiencing a surge of translation into clinical application, so too must the stories of this research and its impact in the lives of patients be translated to a larger audience. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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6:02

Gene and Tonic: The Decline of Pseudoscience, An...

Mendelspod Podcast ·

2015/05/08

The New Republic argued in a pice entitled, "The Decline of Pseudoscience," this week that now that the so called "natural" living industry has gone mainstream, "it's days are numbered." Surely Oprah's dumping of Dr. Oz backs this up. But other events this week show a different story. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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5:41

Gene and Tonic: Sexism in Science, How to Spend an...

Mendelspod Podcast ·

2015/05/01

Janitors have had a terribly busy time this week cleaning up all those jaws that were dropped on floors of research labs everywhere around the country.Have you heard about this latest sexism scandal?Two female co-authors of a scientific paper submitted their work to PLOS -- you know, the open access journal. You won’t believe what they heard back from the lone peer reviewer. They were told to go find “one or two male biologists” to be co-authors on the paper to increase its chances of being

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26:55

Participation in Genomics Research a 21st Century...

Mendelspod Podcast ·

2015/04/15

Pharma companies have always had their chief medical officers (CMOs). Now, as the diagnostics industry grows, many kinds of life science companies are filling this important position as well. Sequencing tool makers, direct-to-consumer firms, bioinformatics companies—they’re all appointing CMOs. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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